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Journal of Pharmacokinetics and Pharmacodynamics

Journal of Pharmacokinetics and Pharmacodynamics is a comprehensive resource covering all aspects of pharmacokinetics, pharmacodynamics, and the application of pharmacometrics to drug development and clinical care. It publishes on topics related to pharmacometrics, including population pharmacokinetics, physiologically based pharmacokinetics, systems pharmacology, and machine learning, and includes both theoretical and experimental papers with applications to real-world observations.

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Subject Pharmacology & Pharmacy
Impact Factor 2.8
Quartile Q2
Open Access Type Hybrid
ISSN 1567-567X
eISSN 1573-8744
Invitation Only No
Cost Range Open access APC: £3090.00 GBP / $4690.00 USD / €3890.00 EUR; subscription publishing: no APC.

Submission Instructions

Journal of Pharmacokinetics and Pharmacodynamics accepts the following article types. Click on an article type to view submission instructions.

Original Paper

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must be 150 to 250 words. Abstract must be unstructured within the manuscript order specified for Original Papers.
Manuscript Original Paper submissions must be organized into unnumbered sections in this order: Abstract, Keywords, Introduction, Theoretical, Methods, Results, Discussion, Conclusions, Acknowledgments, Appendices, References, Tables with legends, Figures with legends, Supplementary Files. Manuscript must include 4 to 6 keywords, a disclosure statement, a Data Availability Statement explaining access to supporting data with links or citations to archived datasets and access terms, a Declarations section before the references, author contribution statements, and documentation of any Large Language Model use in the Methods section or a suitable alternative part of the manuscript.
References References must use numbered citations in square brackets. Reference entries must be numbered consecutively, include only works cited in the text that are published or accepted for publication, and include full DOI links where available.
Figures & Tables Figures should be submitted within the body of the text, with large figures submitted separately only if file size causes upload problems, and the manuscript order for Original Papers places tables with legends and figures with legends after the references. Tables and figures must be numbered consecutively in Arabic numerals, cited in text in numerical order, and accompanied by legends or concise captions, with figure captions included in the manuscript text file rather than within the figure files.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be 150 to 250 words.
Manuscript Review articles must include a disclosure statement, a statement of responsibility specifying each author's contribution, and a statement identifying who conceived the article, performed the literature search and data analysis, and drafted and/or critically revised the work.
References Citations must use numbered references in square brackets. Reference list entries must be numbered consecutively and include only works cited in the text that have been published or accepted for publication, with DOIs given as full links when available.
Figures & Tables Figures should be submitted within the body of the text, but large figures may be submitted separately if file size causes upload problems. Tables and figures must be numbered with Arabic numerals, cited in consecutive numerical order, and accompanied by captions, with figure captions included in the manuscript text file rather than in the figure files.
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Recent Publications

A missed synthesis from the 1930s: Teorell, Mayneord, and the origins of physiological PK–TGI modelling

Hitesh B. Mistry

10.1007/s10928-026-10032-z
View Publication

Multi-objective optimization in population pharmacokinetic model selection and optimization: application of NSGA-II in pyDarwin

Xinnong Li, Mark Sale, James Craig, Keith Nieforth, Alex Mazur, Robert R Bies

10.1007/s10928-026-10036-9
View Publication

Development of a novel rabeprazole modified release formulation to reduce the dosing frequency: A trial and triumph with physiologically based biopharmaceutics modeling

Harika Maddukuri, Rajkumar Boddu, Sangmesh Mallikarjun Chaudhari, Anup Avijit Choudhury, Veena Kambam, Sohel Mohammed Khan, Venkat Ramana Naidu, Sanjay Kumar Singh, Anuj Kumar Saini, Sivacharan Kollipara

10.1007/s10928-026-10035-w
View Publication

Adaptive PK/PD model optimization: a comparative analysis of bounded optimization methods for individual BIS prediction

Zheyan Tu, Sean Jeffries, Eric Pelletier, Oliver Cafferty, Joshua Morse, Avinash Sinha, Thomas Hemmerling

10.1007/s10928-026-10033-y
View Publication

Personalized prophylactic therapy optimization in hemophilia A using a hybrid PK-PD-TTE model and deep RL

Mahdi Rabbani, S. Ehsan Razavi, Masoud Goharimanesh, S. Ehsan Razavi

10.1007/s10928-026-10041-y
View Publication

Frequently asked questions

How long does it take to publish?

Articles are published online after receipt of the corrected proofs.

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Is a cover letter required?

A submission letter may be used when suggesting reviewers, and unpublished material included in the manuscript should be mentioned in a cover letter to the Editor.

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What are the publication costs?

Open access APC is £3090.00 GBP / $4690.00 USD / €3890.00 EUR. Subscription publishing has no APC. Both options are offered after acceptance.

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Research Topics

Statistical Methods in Clinical Trials Pharmacogenetics and Drug Metabolism Statistical Methods and Bayesian Inference Computational Drug Discovery Methods Monoclonal and Polyclonal Antibodies Research Receptor Mechanisms and Signaling Antibiotics Pharmacokinetics and Efficacy Drug Transport and Resistance Mechanisms Optimal Experimental Design Methods Analytical Chemistry and Chromatography Statistical Methods and Inference Protein purification and stability Cardiac electrophysiology and arrhythmias Pharmaceutical studies and practices Health Systems, Economic Evaluations, Quality of Life Gene Regulatory Network Analysis Biosimilars and Bioanalytical Methods Anesthesia and Sedative Agents Mathematical Biology Tumor Growth HER2/EGFR in Cancer Research Advanced Causal Inference Techniques Pharmacological Effects and Toxicity Studies Cancer Treatment and Pharmacology Analytical Methods in Pharmaceuticals Drug Solubulity and Delivery Systems

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