Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Epigenetics & Chromatin

Epigenetics & Chromatin publishes research and reviews that provide novel insights into epigenetic inheritance and chromatin-based interactions, with a focus on how gene and chromosomal elements are regulated and how their activities are maintained during cell division, differentiation, and environmental alteration. The journal is affiliated with the International Society for Molecular and Clinical Epigenetics and states that peer review is led by experienced editors.

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Subject Genetics & Heredity

Impact Factor 3.5

Quartile Q2

Open Access Type Open

eISSN 1756-8935

Invitation Only No

Cost Range The current APC is £2490.00 GBP / $3290.00 USD / €2790.00 EUR, subject to VAT or local taxes where applicable.

Submission Instructions

Epigenetics & Chromatin accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published in Epigenetics & Chromatin, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, and confirm the content has not been published or submitted elsewhere.

Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Results, and Conclusions.

Manuscript Manuscript must include a title page and the sections Background, Methods, Results, Discussion, Conclusions, and Declarations. Manuscript must include three to ten keywords, include all required subsections under Declarations with 'Not applicable' where relevant, and document any use of a Large Language Model in the Methods section or another suitable section if Methods is unavailable.

References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and publicly available preprints may be cited, unpublished abstracts/data and personal communications must be excluded from the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and web references must be numbered and listed in full with site title, URL, and access date.

Figures & Tables Figure titles and legends must appear in the main manuscript rather than in graphic files, tables shorter than one page may be placed within the manuscript, and tables longer than one page may be placed at the end with an in-text callout. Figures must be numbered in text order and uploaded in that order with multipanel figures as single composite files, while tables must be numbered and cited sequentially in Arabic numerals and must be created with the word processor's table function rather than embedded as figures or spreadsheet files.

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Review

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published in Epigenetics & Chromatin, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.

Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include Background, Main body of the abstract, and short Conclusion.

Manuscript Manuscript must include a title page, abstract, Background section, Main text section, Conclusions section, and a Declarations section. Manuscript must include three to ten keywords, a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, and Acknowledgements, use 'Not applicable' for irrelevant Declarations sections, provide a list of abbreviations if abbreviations are used, and document any use of a Large Language Model in the Methods section or another suitable section if no Methods section is available.

References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and publicly available e-prints or preprints may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web links and URLs must be assigned a reference number and included in the reference list with the site title, full URL, and access date.

Figures & Tables Figure titles and legends must be provided in the main manuscript, tables shorter than one page can be placed within the manuscript, and tables longer than one page can be placed at the end of the document with their intended location cited in the text. Figures must be numbered in the order first mentioned and multi-panel figures submitted as a single composite file, while tables must be numbered and cited in sequence and created using the word processor's Table object rather than embedded as figures or spreadsheet files.

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Methodology

Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Results, and Conclusions.

Manuscript Manuscript should be organized with Background, Methods, Results, Discussion, Conclusions, and a Declarations section containing all required subheadings. Manuscript must include three to ten keywords, a Declarations section with all subheadings included and marked 'Not applicable' when irrelevant, and any use of a Large Language Model must be documented in the Methods section.

References References must use Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, or publicly available e-prints/preprints may be cited, unpublished abstracts/data and personal communications must be excluded from the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and web links or URLs must be numbered and listed as full references with site title, URL, and access date.

Figures & Tables Figure titles and legends must appear in the main manuscript rather than the image files, tables shorter than one page can be placed within the manuscript, and tables longer than one page can be placed at the end of the document with their position indicated in the text. Figures must be numbered in text order and multi-panel figures submitted as a single composite file, while tables must be numbered in sequence, created using the word processor's table function, and not embedded as figures or spreadsheet files.

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Comment

Cover Letter A cover letter is required. The cover letter must explain why the manuscript should be published in Epigenetics & Chromatin, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.

Abstract An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include Background, Main body of the abstract, and short Conclusion.

Manuscript Comments must include Background, Main text, and Conclusions sections, along with a Declarations section containing the required subheadings. Comments must include three to ten keywords, a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and optional Authors' information, and any use of a Large Language Model must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.

References Comments may include a maximum of ten references. References must follow Vancouver style. Only articles, clinical trial registration records, and abstracts that are published, in press, or available through public e-print or preprint servers may be cited, unpublished abstracts, unpublished data, and personal communications must be excluded from the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and dataset identifiers including DOIs must be given as full URLs.

Figures & Tables Tables shorter than one page may be placed within the manuscript, tables longer than one page may be placed at the end of the document, figure titles and legends must appear in the main manuscript rather than in the graphic file, and figures must be uploaded in the order first cited. Multi-panel figures must be submitted as a single composite file, tables must not be embedded as figures or spreadsheet files, and tables must be created using the word processor's Table object.

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Recent Publications

H1.3 depletion in AML cells prompts H1.2 redistribution, chromatin remodeling and cell cycle defects

Clara Tellez-Quijorna, Lia N’Guyen, Núria Serna-Pujol, Maeva Rodies, Pau Homs-Aguadé, Julien Vernerey, Albert Jordan, Estelle Duprez

10.1186/s13072-026-00679-w

View Publication

From two to one: spatiotemporal mapping of chromatin remodelling in the protamine-lacking early zygote of zebrafish

Pustovalova Eleonora, Franek Roman, Essaikiammal Sodalai Muthu Konar, Sanovec Ondrej, Frolikova Michaela, Psenicka Martin, Komrskova Katerina, Dedukh Dmitrij

10.1186/s13072-026-00670-5

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Host-cell dependent epigenetic profiles associated with survival outcomes in T. gondii infection

Loic Ciampossin, Arzu Ulu, Todd Lenz, Zehao Li, Steven Abel, Sandeep Srivastava, Michael White, Emma Wilson, Karine G. Le Roch

10.1186/s13072-026-00678-x

View Publication

Temporal stratification of promoter-proximal versus enhancer VDR binding directs vitamin D-responsive transcription

Priman Alfred Fau, Antonio Neme, Sabine Seuter, Carsten Carlberg

10.1186/s13072-026-00677-y

View Publication

Epigenetic deciphering of ovarian aging: multilayer interactive mechanisms and targeted reversal strategies

Ye Zhang, Yan Yang, Qianhui Liao, Xiyu Chen, Kang Wang, Ruyi Zhang, Jing Li, Huiping Liu

10.1186/s13072-026-00664-3

View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 2 days.

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Is a cover letter required?

A cover letter is required and should explain why the manuscript should be published in Epigenetics & Chromatin, address any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the submission, confirm that the manuscript has not been published or submitted elsewhere, and identify the special issue name when applicable. Authors may also use the cover letter to suggest preferred or non-preferred peer reviewers.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £2490.00 GBP / $3290.00 USD / €2790.00 EUR, subject to VAT or local taxes where applicable. Waivers and discounts may be available.

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Research Topics

Genomics and Chromatin Dynamics Epigenetics and DNA Methylation Chromosomal and Genetic Variations Cancer-related gene regulation Genetic Syndromes and Imprinting Developmental Biology and Gene Regulation RNA Research and Splicing RNA modifications and cancer Chromatin Remodeling and Cancer Pluripotent Stem Cells Research DNA Repair Mechanisms Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Diverse Scientific and Economic Studies Academic Publishing and Open Access Histone Deacetylase Inhibitors Research Protein Degradation and Inhibitors Ubiquitin and proteasome pathways Genetics and Neurodevelopmental Disorders Plant Molecular Biology Research Genomic variations and chromosomal abnormalities Genomics and Rare Diseases Reproductive Biology and Fertility CRISPR and Genetic Engineering Sperm and Testicular Function Cancer-related molecular mechanisms research

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