G&

Genes & Diseases

Genes & Diseases is a journal for molecular and translational medicine that focuses on investigations on the molecular bases and experimental therapeutics of human diseases. It publishes rigorously peer-reviewed original articles and authoritative reviews in basic and translational biomedical research, including molecular biology, molecular genetics, cell biology, cancer biology, immunity and infection, neuroscience, gene and cell-based therapies, and regenerative medicine.

Looking to publish in Genes & Diseases? Livewrite integrates seamlessly with Word to help you write, edit, and format faster.

Try Livewrite Now
Subject Genetics & Heredity
Impact Factor 9.4
Quartile Q1
Open Access Type Open
ISSN 2352-4820
eISSN 2352-3042
Invitation Only No
Cost Range Article Publishing Charge (APC): USD 3,000 (excluding taxes).

Submission Instructions

Genes & Diseases accepts the following article types. Click on an article type to view submission instructions.

Enabling And Emerging Technologies

Cover Letter A one-page cover letter is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, briefly explain the conceptual advance and broad significance of the findings, state that the work is not under consideration by any other primary scientific journals, and confirm that all authors have read and concurred with the manuscript.
Abstract An abstract is required. Abstract must be unstructured and must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 6,000 words excluding abstract, references, figures, and tables. Manuscript must be structured as Abstract, Introduction, Material and Methods, Results, Discussion, Author contributions, Conflict of Interests, Funding, Acknowledgements, Appendix if applicable, and References. Manuscript must include at least five relevant keywords in alphabetical order and the sections Author contributions, Conflict of Interests, Funding, and Acknowledgements.
References Manuscript may include a maximum of 80 references. References must be cited using consecutive superscript Arabic numerals in the order of appearance and listed in the same numerical order.
Figures & Tables Manuscript may include a maximum of 8 tables and figures. Figures must be submitted as separate files and figure captions must be provided separately. Tables must be numbered consecutively in citation order and figures must be numbered according to their sequence in the text.
Reformat to Genes & Diseases using Livewrite Premium

Clinical And Translational Investigation

Cover Letter A one-page cover letter from the corresponding author is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and significance to a broad readership, a statement that the work is not under consideration by another primary scientific journal, and a statement that all authors have read and concurred with the manuscript content.
Abstract An abstract is required. Abstract must be unstructured and must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 6,000 words excluding abstract, references, figures, and tables. Manuscript must be structured as Abstract, Introduction, Material and Methods, Results, Discussion, Author contributions, Conflict of Interests, Funding, Acknowledgements, Appendix if applicable, and References. At least five relevant keywords in alphabetical order must be provided below the abstract, and the manuscript must include Author contributions, Conflict of Interests, Funding, and Acknowledgements sections.
References Manuscript may include a maximum of 80 references. References must be cited by consecutive superscript Arabic numerals in the order of appearance, and the reference list must be numbered in that same order.
Figures & Tables Manuscript may include a maximum of 8 tables and figures. Figure captions must be supplied separately, each illustration must be submitted as a separate file, and source files are required whether or not figures are embedded in the text. Tables must be numbered consecutively with concise, self-explanatory headings, and all symbols and abbreviations used in figures must be explained.
Reformat to Genes & Diseases using Livewrite Premium

Review Article

Cover Letter A one-page cover letter is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and significance to a broad readership, a statement that the work is not under consideration by any other primary scientific journals, and a statement that all authors have read and concurred with the manuscript content.
Abstract An abstract is required. Abstract must be unstructured and no more than 250 words. Abstract must be unstructured.
Manuscript Manuscript should usually be less than 8,000 words excluding abstract, references, figures, and tables. Manuscript must be structured as Abstract, Introduction, main text subheadings, Conclusions, Author contributions, Conflict of Interests, Funding, Acknowledgements, Appendix if applicable, and References. At least five relevant keywords in alphabetical order must be provided below the abstract, and the manuscript must include Author contributions, Conflict of Interests, Funding, and Acknowledgements sections.
References Manuscript should usually include fewer than 300 references. References must be cited by consecutive superscript Arabic numerals in the order of appearance and listed in the same numerical order.
Figures & Tables Manuscript may include a maximum of 6 tables and figures. Captions for figures must be supplied separately and each illustration must be submitted as a separate file. Tables must be numbered consecutively with concise, self-explanatory headings, and figures must be numbered according to their sequence in the text with captions including a brief title and description.
Reformat to Genes & Diseases using Livewrite Premium

Full Length Article

Cover Letter A one-page cover letter from the corresponding author is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and significance to a broad readership, a statement that the work has not been under consideration by any other primary scientific journals, and a statement that all authors have read and concurred with the manuscript content.
Abstract An abstract is required. Abstract must be unstructured and must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 6,000 words excluding abstract, references, figures, and tables. Text must be structured as Abstract, Introduction, Material and Methods, Results, Discussion, Author contributions, Conflict of Interests, Funding, Acknowledgements, Appendix if applicable, and References. At least five relevant keywords in alphabetical order must be provided below the abstract, and the manuscript must include Author contributions, Conflict of Interests, Funding, and Acknowledgements sections.
References Manuscript may include a maximum of 80 references. References must be cited by consecutive superscript Arabic numerals in the order they appear in the text, and the reference list must be numbered in that same order.
Figures & Tables Manuscript may include a maximum of 8 tables and figures. Each illustration must be submitted as a separate file and figure captions must be supplied separately. Tables must be numbered consecutively in citation order and illustrations must be numbered according to their sequence in the text.
Reformat to Genes & Diseases using Livewrite Premium

Research Paper

Cover Letter A one-page cover letter is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and significance to a broad readership, a statement that the work has not been under consideration by any other primary scientific journals, and a statement that all authors have read and concurred with the manuscript content.
Abstract An abstract is required. Abstract must be less than 250 words. Abstract must be unstructured.
Manuscript Article must include a title page, at least 5 relevant keywords in alphabetical order, main text, and where applicable acknowledgments, tables, figure captions, and figure files. A summary declaration of interest statement must be included in the title page file if double anonymized or in the manuscript file if single anonymized, author contribution descriptions must be provided, and at least 5 relevant keywords in alphabetical order must appear below the abstract.
References References must use a numbered citation style with consecutive superscript Arabic numerals in order of appearance. Reference numerals must appear outside periods and commas and inside colons and semicolons, the reference list must be numbered in order of appearance, DOIs must be added when supplied, and all listed references must be cited in the text, tables, or figures and vice versa.
Figures & Tables Each illustration must be submitted as a separate file and figure captions must be supplied separately. Tables must be numbered consecutively in citation order with concise, self-explanatory headings, and illustrations must be numbered according to their sequence in the text with all symbols and abbreviations explained.
Reformat to Genes & Diseases using Livewrite Premium

Review Paper(Unsolicited)

Cover Letter A one-page cover letter from the corresponding author is required. The cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and significance to a broad readership, a statement that the work is not under consideration by any other primary scientific journals, and a statement that all authors have read and concurred with the manuscript content.
Abstract An abstract is required. Abstract must be less than 250 words. Abstract must be unstructured.
Manuscript The article must include a title page, title, author names and affiliations, main text, and acknowledgments where applicable. At least five relevant keywords in alphabetical order must be provided below the abstract, and an authorship contribution description using the listed contribution categories must be included.
References References must use a numbered citation style with consecutive superscript Arabic numerals. References must be numbered in the order of first appearance in the text, listed in the same order, include DOIs when supplied, and every listed reference must be cited in the text, tables, or figures and vice versa.
Figures & Tables Figure captions must be supplied separately and each illustration must be submitted as a separate file, while all tables must be included in the article where applicable. Tables must be numbered consecutively with concise, self-explanatory headings, and figures must be numbered according to their sequence in the text with captions that include a brief title and explanation of symbols and abbreviations.
Reformat to Genes & Diseases using Livewrite Premium

Rapid Communication

Cover Letter A one-page cover letter is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, briefly explain the conceptual advance and significance to a broad readership, and state that the work is not under consideration by any other primary scientific journals and that all authors have read and concurred with the manuscript.
Abstract Abstract is not required.
Manuscript Manuscript must not exceed 1,200 words excluding references, figures, and tables. Manuscript may optionally begin with the salutation 'To the Editor---'. At least 5 relevant keywords in alphabetical order must be provided below the abstract, and the article must include a title page.
References Manuscript may include a maximum of 5 references. References must be cited using consecutive superscript Arabic numerals in the order of appearance, and the reference list must be numbered in that same order.
Figures & Tables Manuscript may include a maximum of 1 table or figure. Figure captions must be supplied separately and each illustration must be submitted as a separate file.
Reformat to Genes & Diseases using Livewrite Premium

Letters

Cover Letter A one-page cover letter is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and broad significance of the findings, a statement that the work is not under consideration by any other primary scientific journals, and a statement that all authors have read and concurred with the manuscript content.
Abstract An abstract is not required.
Manuscript Manuscript must not exceed 1,200 words excluding references, figure, and table. Manuscript must begin with the salutation 'Dear Editor:'. At least 5 relevant keywords in alphabetical order must be included below the abstract or with the article.
References Manuscript may include a maximum of 5 references. References must be cited by consecutive superscript Arabic numerals in the order of appearance and listed in the same numerical order.
Figures & Tables Manuscript may include a maximum of 1 table or figure. Each illustration must be submitted as a separate file, figure captions must be supplied separately, and source files of figures and tables are required whether or not they are embedded in the text. Tables must be numbered consecutively and have a concise, self-explanatory heading, and figures must be numbered according to their sequence in the text with captions that include a brief title and description.
Reformat to Genes & Diseases using Livewrite Premium

Correspondence

Cover Letter A one-page cover letter from the corresponding author is required. Cover letter must include the corresponding author's full postal address, telephone number, and e-mail address, a brief explanation of the conceptual advance and significance to a broad readership, a statement that the work is not under consideration by any other primary scientific journals, and confirmation that all authors have read and concurred with the manuscript.
Abstract Abstract is not required.
Manuscript Manuscript must not exceed 1,000 words excluding references. At least 5 relevant keywords in alphabetical order must be provided.
References Manuscript may include a maximum of 5 references. References must be cited by consecutive superscript Arabic numerals in the order they appear, and the reference list must be numbered in that same order.
Figures & Tables Manuscript may include a maximum of 1 table or figure. Figure captions must be supplied separately and each illustration must be submitted as a separate file.
Reformat to Genes & Diseases using Livewrite Premium

Recent Publications

Dual-signal in situ programming of CD14+ monocytes enables rapid endothelialization and vascular regeneration

Sicheng Chen, Qiying Wu, Zeguo Chen, Chao Xie, Liang Yi, Chao Deng, Wei Jiang, Ting Lu, Can Huang, Yuhong Liu, Zhongshi Wu

10.1016/j.gendis.2026.102209
View Publication

Patient-specific iPSCs-derived neuronal models of spinocerebellar ataxia type 1 as a platform for studying calcium mishandling

Dmitriy Grekhnev, Egor Volovikov, Olga Lebedeva, Anton Skopin, Konstantin Gusev, Sergey Klyushnikov, Alexandra Bogomazova, Guanghui Wang, Elena Zerkalenkova, Sergey Illarioshkin, Maria Lagarkova, Elena Kaznacheyeva, Vladimir Vigont

10.1016/j.gendis.2026.102215
View Publication

Maternal high-fat diet intake ameliorates the progression of nephritis in male lupus-prone offspring via mTOR/NFκB/arachidonic acid signaling cascade

Shuang Liu, Imai Matome, Yasuyuki Suzuki, Takashi Sugiyama, Masaki Mogi

10.1016/j.gendis.2026.102216
View Publication

Non-invasive malignancy assessment of glioma and meningioma via a cfDNA fragmentomics-based ensemble model

Ye Cheng, Liguo Ye, Huiyu Yang, Xin Guan, Xiaolei Zhang, Tao Zeng, Yiming Zhang, Menglu Xue, Cuicui Liu, Jiani C. Yin, Xiaoying Wu, Na Bai, Guoguang Zhao, Xinru Xiao

10.1016/j.gendis.2026.102197
View Publication

Impact of microRNAs on tumor-associated factors and signaling pathways: Mechanisms and perspectives

Safir Ullah Khan, Munir Ullah Khan, Mohammed Alissa, Ali G. Alkhathami, Ghada M. Alnafesah, Muhammad Suleman, Erika Rimondi, Elisabetta Melloni, Paola Secchiero, Annalisa Marcuzzi, Sergio Crovella

10.1016/j.gendis.2026.102196
View Publication

Frequently asked questions

How long does it take to publish?

20 days submission to first decision; 67 days submission to decision after review; 173 days submission to acceptance; 37 days from acceptance to first online publication.

Reformat to Genes & Diseases using Livewrite Premium

Is a cover letter required?

A one-page cover letter from the corresponding author is required. It must include the full postal address, telephone number, and e-mail address, explain the conceptual advance and significance of the findings, and state that the work is not under consideration elsewhere and that all authors have read and concurred with the manuscript.

Reformat to Genes & Diseases using Livewrite Premium

What are the publication costs?

Article Publishing Charge (APC): USD 3,000 (excluding taxes).

Reformat to Genes & Diseases using Livewrite Premium

Research Topics

RNA modifications and cancer Cancer-related molecular mechanisms research Epigenetics and DNA Methylation MicroRNA in disease regulation Ferroptosis and cancer prognosis Circular RNAs in diseases Cancer, Hypoxia, and Metabolism Cancer-related gene regulation Ubiquitin and proteasome pathways RNA Research and Splicing Cancer Immunotherapy and Biomarkers Autophagy in Disease and Therapy Cancer Cells and Metastasis Mitochondrial Function and Pathology Cancer Genomics and Diagnostics Cancer-related Molecular Pathways CRISPR and Genetic Engineering Immune cells in cancer Liver Disease Diagnosis and Treatment Extracellular vesicles in disease Immune Cell Function and Interaction Cancer, Lipids, and Metabolism interferon and immune responses RNA regulation and disease Endoplasmic Reticulum Stress and Disease

Related Journals

RP
Respiratory Physiology & Neurobiology Elsevier BV
PE
Parasite Epidemiology And Control Elsevier BV
JO
Journal Of Genetics And Genomics Elsevier BV
TI
Trends In Anaesthesia And Critical Care Elsevier BV
JO
Journal Of The American Society Of Echocardiography Elsevier BV
IJ
International Journal Of Mycobacteriology Elsevier BV