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Current Opinion in Toxicology

Current Opinion in Toxicology is a review-focused toxicology journal affiliated with the International Union of Toxicology. It publishes polished, concise, and timely reviews and opinions intended to stimulate scientifically grounded, interdisciplinary, multi-scale debate, with emphasis on recent literature and expert evaluation of important papers. The journal is organized into seven themed sections and accepts invited submissions as well as direct submissions to the General Toxicology section; original research papers and systematic reviews are not considered.

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Subject Toxicology
Impact Factor 3.6
Quartile Q2
Open Access Type Hybrid
ISSN 2468-2020
eISSN 2468-2020
Invitation Only No
Cost Range Open access APC: USD 4200 excluding taxes; subscription publication: no open access publication fee.

Submission Instructions

Current Opinion in Toxicology accepts the following article types. Click on an article type to view submission instructions.

Short Reviews

Cover Letter Cover letter is required for direct submissions of Short Reviews. For direct submission, the cover letter must demonstrate the corresponding author's expertise and track record, describe their scientific background and contributions, list relevant peer-reviewed publications, explain the review's scientific need and timeliness, and state how it differs from and advances beyond closely related recent reviews.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Short Reviews should be approximately 2500–4000 words excluding abstract, references, and figure captions. Short Reviews must be opinion-type review articles that provide short annotations to selected important papers and include the text "References and recommended reading" under the reference section followed by the statements identifying * and ** highlighted papers. Short Reviews must include 1 to 7 keywords in English, at least one figure summarizing the main concepts, and a generative AI declaration at the end of the manuscript before the references if AI tools were used in manuscript preparation.
References Short Reviews are limited to 50 references, with at least 10% selected and annotated references from the past 2 years. References must use a numbered square-bracket citation style consistent with Vancouver numbering. References must be listed in order of appearance, use the first 6 authors followed by "et al." when there are more than 6 authors, and include brief annotations marking selected recent papers as * or ** with their significance described.
Figures & Tables Short Reviews must include no more than 4 tables or figures in total and at least one figure. Figures must be supplied as separate files, while tables are submitted within the manuscript as editable text. All figures and tables must be cited in the text, numbered in order of appearance, and accompanied by captions.
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Editorial Overview

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must provide a short overview at the beginning of the section to introduce the reviews and highlight particularly interesting developments. Manuscript must include 1 to 7 keywords in English, and if generative AI tools were used in manuscript preparation, a declaration statement must be placed at the end of the manuscript before the references list.
References References must be cited by number in square brackets and listed in numerical order of appearance. For references with more than 6 authors, list the first 6 authors followed by 'et al.', and abbreviate journal names according to LTWA.
Figures & Tables Figures and other artwork must be uploaded as separate files, and tables must be submitted as editable text rather than images. All tables and figures must be cited in the text, numbered consecutively in order of appearance, and provided with captions.
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Recent Publications

Effect of cannabidiol on traumatic brain injury–related neuronal damage pathways

Ayse Basak Engin, Atilla Engin

10.1016/j.cotox.2026.100575
View Publication

Risk assessment of endocrine disruptors: Does unresolved uncertainties require extra precaution?

Marie Louise Holmer, Marta Axelstad, Anna Beronius, Cecile Michel-Caillet, Terje Svingen

10.1016/j.cotox.2026.100576
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Organ-on-chip systems in micro- and nanoplastic toxicology: A selective revolution for human health

Gurusamy Kutralam-Muniasamy, V.C. Shruti, Fermín Pérez-Guevara, Ricardo Cuenca Alvarez

10.1016/j.cotox.2026.100577
View Publication

Regulating controlled substances to advance research and protect public health

Amy Inselman, Fang Liu

10.1016/j.cotox.2026.100587
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Emerging therapeutics and safety: Transdisciplinary science to address unique safety challenges of cannabis and psychedelics

Maxwell.C.K. Leung, Benjamin W. Hatten, Linda G. Roberts, William Slikker, Jr.

10.1016/j.cotox.2026.100590
View Publication

Frequently asked questions

How long does it take to publish?

26 days from submission to first decision; 74 days from submission to decision after review; 125 days from submission to acceptance; 6 days from acceptance to online publication.

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Is a cover letter required?

A cover letter is required for direct submissions. It must demonstrate the corresponding author's expertise and track record in the subject area, include relevant peer-reviewed publications, explain the scientific need and timeliness of the proposed review, and clarify how the submission advances beyond closely related recent reviews, perspectives, or viewpoints.

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What are the publication costs?

Open access APC: USD 4200 excluding taxes. Subscription publication has no open access publication fee.

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Research Topics

Effects and risks of endocrine disrupting chemicals Animal testing and alternatives Carcinogens and Genotoxicity Assessment Toxic Organic Pollutants Impact Diverse Scientific and Economic Studies Human auditory perception and evaluation Educational Robotics and Engineering Computational Drug Discovery Methods Genomics, phytochemicals, and oxidative stress Heavy Metal Exposure and Toxicity Immunotoxicology and immune responses Epigenetics and DNA Methylation Air Quality and Health Impacts Environmental Toxicology and Ecotoxicology Pesticide Exposure and Toxicity Microplastics and Plastic Pollution Health, Environment, Cognitive Aging Pharmacogenetics and Drug Metabolism Single-cell and spatial transcriptomics Cannabis and Cannabinoid Research 3D Printing in Biomedical Research Metabolomics and Mass Spectrometry Studies Trace Elements in Health Drug-Induced Hepatotoxicity and Protection Birth, Development, and Health