JO

Journal of Clinical Epidemiology

Journal of Clinical Epidemiology aims to advance science that can improve health care decision-making and contribute to the evolving discipline of clinical epidemiology. It publishes methods-focused articles across the research ecosystem, including primary research, evidence syntheses, guidelines, implementation science, registered reports, protocols, and simulation studies, with an emphasis on inclusive research and health equity.

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Subject Health Care Sciences & Services, Public, Environmental & Occupational Health
Impact Factor 5.2
Quartile Q1
Open Access Type Hybrid
ISSN 0895-4356
eISSN 1878-5921
Invitation Only No
Cost Range Open Access APC: USD 4,370 (excluding taxes); subscription publication: no publication fee charged to authors.

Submission Instructions

Journal of Clinical Epidemiology accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter A cover letter is required. The cover letter must state that the material has not been published or submitted elsewhere, explain how the paper relates to methods research in clinical epidemiology, include a preprint link if applicable, and include a reprint or manuscript for any preliminary publication other than an abstract of 400 words or fewer.
Abstract An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must use Introduction or background, Methods, Results, and Discussion headings, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript Original Research articles must not exceed 3,000 words. Articles must be divided into clearly defined and numbered sections, and the abstract must not be included within the section numbering. The manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a 'What is new' box of up to 5 points below the abstract, and an AI use declaration section before the references if generative AI was used in manuscript preparation.
References Original Research articles must not exceed 100 references. References must be cited using numbered superscript Arabic numerals in order of appearance. The reference list must be numbered in citation order and include applicable bibliographic details, with journal names abbreviated according to LTWA.
Figures & Tables Original Research articles must not exceed 5 figures and 5 tables. Tables must be placed next to the relevant text or on separate pages at the end of the article, and figures must be supplied as separate files. Tables must be submitted as editable text rather than images and both tables and figures must be cited in the text, numbered consecutively, and accompanied by captions.
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Living Reviews

Cover Letter Cover letter is required. Cover letter must state that the material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include any preprint link, and be accompanied by a reprint or manuscript if there has been preliminary publication other than an abstract of not more than 400 words.
Abstract Abstract is required. Abstract must not exceed 350 words. Abstract must be structured using appropriate headings. Structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript Manuscript must not exceed 3,000 words. Articles must be divided into clearly defined and numbered sections, and Living Reviews must include the schedule and criteria for further updates. Manuscript submission must include 1 to 7 English keywords, article highlights of 3 to 5 bullet points, a "What is new" box of up to 5 points below the abstract, CRediT author contribution acknowledgement, declarations including competing interests and funding, and an AI-use declaration in a new section before the references if generative AI was used in manuscript preparation.
References References must not exceed 100. References must be cited using superscript Arabic numerals in numerical order. Reference list entries must be numbered in the order cited and include applicable bibliographic details, with journal names abbreviated according to LTWA.
Figures & Tables Living Reviews must not exceed 5 figures and 5 tables. Figures must be uploaded as separate files, while tables must be placed next to the relevant text or on separate pages at the end of the article. Tables must be editable text with captions and all figures and tables must be cited and numbered consecutively in the manuscript.
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Living Guidelines

Cover Letter A cover letter is required. The cover letter must state that the material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include any preprint link, and be accompanied by a reprint or manuscript for any preliminary publication other than an abstract of 400 words or fewer.
Abstract Abstract must not exceed 350 words. Abstract must be structured. The structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript Manuscript must not exceed 3,000 words. Articles must be divided into clearly defined and numbered sections, and Living Guidelines must include the schedule and criteria for further updates. The manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a 'What is new' box of up to 5 points placed below the abstract before the introduction, declarations including funding and competing interests, and an AI-use declaration in a new section before the references if generative AI was used in manuscript preparation.
References References must not exceed 100. References must be cited by superscript Arabic numerals in order of appearance and listed in the same order.
Figures & Tables Living Guidelines must not exceed 5 figures and 5 tables. Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be submitted as editable text rather than images and both figures and tables must be cited in the manuscript text and numbered consecutively.
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Registered Reports

Cover Letter Cover letter is required. Cover letter must state that the material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include a link to any preprint, and include a reprint or manuscript if there has been preliminary publication other than an abstract of no more than 400 words.
Abstract Abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript Registered Reports must be submitted as article type “Registered Report Stage I” to pre-register the research and “Registered Report Stage II” for the completed study. Manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a "What is new" box with up to 5 points below the abstract before the introduction, numbered sections, acknowledgements before the references, a declaration of generative AI use in a new section before the references if applicable, and CRediT author contribution statements.
References References may be in any consistent style or format at submission. References must be cited in the text with superscript Arabic numerals in order of appearance and listed numerically in that same order.
Figures & Tables Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be editable text with captions and figures must be cited, numbered in sequence, submitted as separate files, and accompanied by captions.
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Letters

Cover Letter Cover letter is required. Cover letter must state that the material has not been published or submitted elsewhere, explain how the paper relates to methods research in clinical epidemiology, include any preprint link, and include a reprint or manuscript for any preliminary publication other than an abstract of no more than 400 words.
Abstract Abstract must not exceed 350 words. Abstract must be structured. Structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in the Introduction or background and the conclusion in the Discussion.
Manuscript Letter must not exceed 500 words. Articles must be divided into clearly defined and numbered sections, and the abstract must not be included within the section numbering. Manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a 'What is new' box of up to 5 points below the abstract, required declarations including competing interests and funding, and an AI-use declaration in a new section before the references if generative AI was used in manuscript preparation.
References References must be cited using superscript Arabic numerals in the text and numbered in the reference list in order of appearance. References may be in any consistent style at submission, but must include core bibliographic details where applicable and journal titles must be abbreviated according to LTWA.
Figures & Tables Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be editable text with captions and figures must each be cited, numbered, and accompanied by a caption.
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Recent Publications

The suboptimal methodological quality of non-Cochrane reviews on hyoscine butylbromide to shorten labour duration raises concerns about their conclusions: a meta-research study

Loukia M. Spineli, Anna Bludau, Patricia Könneker, Anne C. Hallet, Anne Christine Manawa Nougho, Lotte Katrijn ten Brinke, Hanna Gehling, Mechthild M. Gross, Laura A. Zinsser

10.1016/j.jclinepi.2026.112355
View Publication

Area under the likelihood curve as a measure of evidential weight in nonsignificant meta-analyses: A meta-epidemiological study

Amin Sharifan, Curtis Harrod, Andreea Dobrescu, Gerald Gartlehner

10.1016/j.jclinepi.2026.112356
View Publication

Integrating Environmental Impacts into Economic Evaluation of Health Interventions: Moving Beyond Isolated Metrics

Mourgues Charline, Bourguignon Nathalie, Amakoué Yrkamba Bienvenu

10.1016/j.jclinepi.2026.112357
View Publication

Engaging policymakers in the development of clinical practice guidelines: a global survey of current practice in guideline development

Samantha Chakraborty, Viona Riskikallail, Anneliese Synnot, Grace Wangge, Tari Turner, Tanya Millard

10.1016/j.jclinepi.2026.112370
View Publication

Methodological innovation to support incorporation of environmental impacts in health research

Beatriz Goulao, Dwayne Boyers, Kristin Konnyu

10.1016/j.jclinepi.2026.112358
View Publication

Frequently asked questions

How long does it take to publish?

7 days from submission to first decision; 62 days from submission to decision after review; 128 days from submission to acceptance; 6 days from acceptance to first online publication.

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Is a cover letter required?

A cover letter is required. It must state that the submitted material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include a link to any publicly available preprint, and include a reprint or manuscript if there has been preliminary publication other than an abstract of not more than 400 words. Protocol submissions should clearly outline the purpose of publishing the protocol.

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What are the publication costs?

Open access APC is USD 4,370 excluding taxes. Subscription publication has no publication fee charged to authors.

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Research Topics

Meta-analysis and systematic reviews Health Systems, Economic Evaluations, Quality of Life Statistical Methods in Clinical Trials Diverse Scientific and Economic Studies Advanced Causal Inference Techniques Clinical practice guidelines implementation Delphi Technique in Research Health Policy Implementation Science Reliability and Agreement in Measurement Health disparities and outcomes Healthcare cost, quality, practices Ethics in Clinical Research Chronic Disease Management Strategies Human auditory perception and evaluation Health Sciences Research and Education Educational Robotics and Engineering Healthcare Policy and Management Statistical Methods and Bayesian Inference Primary Care and Health Outcomes Ferroelectric and Negative Capacitance Devices Big Data and Digital Economy Musculoskeletal pain and rehabilitation Global Cancer Incidence and Screening Blood Pressure and Hypertension Studies Health and Medical Research Impacts

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