Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Journal of Clinical Epidemiology aims to advance science that can improve health care decision-making and contribute to the evolving discipline of clinical epidemiology. It publishes methods-focused articles across the research ecosystem, including primary research, evidence syntheses, guidelines, implementation science, registered reports, protocols, and simulation studies, with an emphasis on inclusive research and health equity.
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Impact Factor
5.2
Quartile
Q1
Open Access Type
Hybrid
ISSN
0895-4356
eISSN
1878-5921
Invitation Only
No
Cost Range
Open Access APC: USD 4,370 (excluding taxes); subscription publication: no publication fee charged to authors.
Submission Instructions
Journal of Clinical Epidemiology accepts the following article types. Click on an article type to view submission instructions.
Original Research
Cover Letter
A cover letter is required. The cover letter must state that the material has not been published or submitted elsewhere, explain how the paper relates to methods research in clinical epidemiology, include a preprint link if applicable, and include a reprint or manuscript for any preliminary publication other than an abstract of 400 words or fewer.
Abstract
An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must use Introduction or background, Methods, Results, and Discussion headings, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript
Original Research articles must not exceed 3,000 words. Articles must be divided into clearly defined and numbered sections, and the abstract must not be included within the section numbering. The manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a 'What is new' box of up to 5 points below the abstract, and an AI use declaration section before the references if generative AI was used in manuscript preparation.
References
Original Research articles must not exceed 100 references. References must be cited using numbered superscript Arabic numerals in order of appearance. The reference list must be numbered in citation order and include applicable bibliographic details, with journal names abbreviated according to LTWA.
Figures & Tables
Original Research articles must not exceed 5 figures and 5 tables. Tables must be placed next to the relevant text or on separate pages at the end of the article, and figures must be supplied as separate files. Tables must be submitted as editable text rather than images and both tables and figures must be cited in the text, numbered consecutively, and accompanied by captions.
Living Reviews
Cover Letter
Cover letter is required. Cover letter must state that the material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include any preprint link, and be accompanied by a reprint or manuscript if there has been preliminary publication other than an abstract of not more than 400 words.
Abstract
Abstract is required. Abstract must not exceed 350 words. Abstract must be structured using appropriate headings. Structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript
Manuscript must not exceed 3,000 words. Articles must be divided into clearly defined and numbered sections, and Living Reviews must include the schedule and criteria for further updates. Manuscript submission must include 1 to 7 English keywords, article highlights of 3 to 5 bullet points, a "What is new" box of up to 5 points below the abstract, CRediT author contribution acknowledgement, declarations including competing interests and funding, and an AI-use declaration in a new section before the references if generative AI was used in manuscript preparation.
References
References must not exceed 100. References must be cited using superscript Arabic numerals in numerical order. Reference list entries must be numbered in the order cited and include applicable bibliographic details, with journal names abbreviated according to LTWA.
Figures & Tables
Living Reviews must not exceed 5 figures and 5 tables. Figures must be uploaded as separate files, while tables must be placed next to the relevant text or on separate pages at the end of the article. Tables must be editable text with captions and all figures and tables must be cited and numbered consecutively in the manuscript.
Living Guidelines
Cover Letter
A cover letter is required. The cover letter must state that the material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include any preprint link, and be accompanied by a reprint or manuscript for any preliminary publication other than an abstract of 400 words or fewer.
Abstract
Abstract must not exceed 350 words. Abstract must be structured. The structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript
Manuscript must not exceed 3,000 words. Articles must be divided into clearly defined and numbered sections, and Living Guidelines must include the schedule and criteria for further updates. The manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a 'What is new' box of up to 5 points placed below the abstract before the introduction, declarations including funding and competing interests, and an AI-use declaration in a new section before the references if generative AI was used in manuscript preparation.
References
References must not exceed 100. References must be cited by superscript Arabic numerals in order of appearance and listed in the same order.
Figures & Tables
Living Guidelines must not exceed 5 figures and 5 tables. Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be submitted as editable text rather than images and both figures and tables must be cited in the manuscript text and numbered consecutively.
Registered Reports
Cover Letter
Cover letter is required. Cover letter must state that the material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include a link to any preprint, and include a reprint or manuscript if there has been preliminary publication other than an abstract of no more than 400 words.
Abstract
Abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in Introduction or background and the conclusion in Discussion.
Manuscript
Registered Reports must be submitted as article type “Registered Report Stage I” to pre-register the research and “Registered Report Stage II” for the completed study. Manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a "What is new" box with up to 5 points below the abstract before the introduction, numbered sections, acknowledgements before the references, a declaration of generative AI use in a new section before the references if applicable, and CRediT author contribution statements.
References
References may be in any consistent style or format at submission. References must be cited in the text with superscript Arabic numerals in order of appearance and listed numerically in that same order.
Figures & Tables
Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be editable text with captions and figures must be cited, numbered in sequence, submitted as separate files, and accompanied by captions.
Letters
Cover Letter
Cover letter is required. Cover letter must state that the material has not been published or submitted elsewhere, explain how the paper relates to methods research in clinical epidemiology, include any preprint link, and include a reprint or manuscript for any preliminary publication other than an abstract of no more than 400 words.
Abstract
Abstract must not exceed 350 words. Abstract must be structured. Structured abstract must include Introduction or background, Methods, Results, and Discussion, with the objective in the Introduction or background and the conclusion in the Discussion.
Manuscript
Letter must not exceed 500 words. Articles must be divided into clearly defined and numbered sections, and the abstract must not be included within the section numbering. Manuscript must include 1 to 7 keywords, article highlights of 3 to 5 bullet points, a 'What is new' box of up to 5 points below the abstract, required declarations including competing interests and funding, and an AI-use declaration in a new section before the references if generative AI was used in manuscript preparation.
References
References must be cited using superscript Arabic numerals in the text and numbered in the reference list in order of appearance. References may be in any consistent style at submission, but must include core bibliographic details where applicable and journal titles must be abbreviated according to LTWA.
Figures & Tables
Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be editable text with captions and figures must each be cited, numbered, and accompanied by a caption.
Recent Publications
Corrigendum to SPICE-GRADE: simultaneous processing of indirect causal evidence in complex pathways using GRADE - an exploratory case study. [Journal of Clinical Epidemiology, 194C (2026) 112219]
Prashanti Eachempati, Gordon Guyatt, Per Olav Vandvik, Philippe J. Guerin, Prabin Dahal, Karen I. Barnes, Thomas Agoritsas
10.1016/j.jclinepi.2026.112369
View Publication
Prognostic Systematic Reviews: Challenges and Insights-An Example
Jana Khawandi, Daniel G. Rayner, Vinamratha Rao, Niveditha Grimaji, Muayad Azzam, Qais Hamarsha, Hassan Kawtharany, Ali Choaib, Alan S.L. Yu, Ronald D. Perrone, Farid Foroutan, Reem A. Mustafa
10.1016/j.jclinepi.2026.112427
View Publication
Comment on “Estimating diagnostic accuracy under uncertainty about disease status: a sepsis case study”
Werner Vach
10.1016/j.jclinepi.2026.112431
View Publication
Paper mills in evidence synthesis: reported involvement among retracted systematic reviews and meta-analyses
Emir Begagić, Faruk Skenderi, Semir Vranić
10.1016/j.jclinepi.2026.112429
View Publication
A preregistered simulation study provided evidence on the appropriate use of data-driven variable selection in descriptive multivariable regression modeling
Theresa Ullmann, Georg Heinze, Michael Kammer, Daniela Dunkler
10.1016/j.jclinepi.2026.112423
View Publication
Frequently asked questions
How long does it take to publish?
7 days from submission to first decision; 62 days from submission to decision after review; 128 days from submission to acceptance; 6 days from acceptance to first online publication.
Reformat to Journal of Clinical Epidemiology using Livewrite PremiumIs a cover letter required?
A cover letter is required. It must state that the submitted material has not been published and is not under consideration elsewhere, explain how the paper relates to methods research in clinical epidemiology, include a link to any publicly available preprint, and include a reprint or manuscript if there has been preliminary publication other than an abstract of not more than 400 words. Protocol submissions should clearly outline the purpose of publishing the protocol.
Reformat to Journal of Clinical Epidemiology using Livewrite PremiumWhat are the publication costs?
Open access APC is USD 4,370 excluding taxes. Subscription publication has no publication fee charged to authors.
Reformat to Journal of Clinical Epidemiology using Livewrite PremiumResearch Topics
Meta-analysis and systematic reviews
Health Systems, Economic Evaluations, Quality of Life
Statistical Methods in Clinical Trials
Diverse Scientific and Economic Studies
Advanced Causal Inference Techniques
Clinical practice guidelines implementation
Delphi Technique in Research
Health Policy Implementation Science
Reliability and Agreement in Measurement
Health disparities and outcomes
Healthcare cost, quality, practices
Ethics in Clinical Research
Chronic Disease Management Strategies
Human auditory perception and evaluation
Health Sciences Research and Education
Educational Robotics and Engineering
Healthcare Policy and Management
Statistical Methods and Bayesian Inference
Primary Care and Health Outcomes
Ferroelectric and Negative Capacitance Devices
Big Data and Digital Economy
Musculoskeletal pain and rehabilitation
Global Cancer Incidence and Screening
Blood Pressure and Hypertension Studies
Health and Medical Research Impacts