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Frontiers in Cardiovascular Medicine

Frontiers in Cardiovascular Medicine is a multidisciplinary journal publishing peer-reviewed research across basic, translational, and clinical cardiovascular medicine.

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Impact Factor 2.9
Quartile Q2
Open Access Type Open
ISSN 2297-055X
eISSN 2297-055X
Invitation Only No
Cost Range CHF 3,150 for A-Type Articles; CHF 2,500 for B-Type Articles.

Submission Instructions

Frontiers in Cardiovascular Medicine accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following IMRAD.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion, with the Introduction kept succinct and without subheadings. Manuscript must include at least five keywords, a contribution to the field statement, a 200-word scope statement for submission, and any use of generative AI must be acknowledged in the acknowledgements section and in the Methods section if applicable with the tool name, version, model, and source.
References References must include only published or accepted works, list the first six authors followed by et al. with authors’ given names abbreviated to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. Each figure and table must be cited in numerical order in the text, multi-panel figures must label panels as (A), (B), (C), etc., and tables must not be submitted as figures.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Methods, Results, and Discussion, with the specified systematic review content in the Methods, Results, and Discussion sections. Manuscript must include at least five keywords, funding information, a contribution to the field statement, and acknowledgment of any generative AI use in the acknowledgments and methods sections if applicable.
References References must follow the journal reference style, list the first six authors followed by et al. with authors’ given names abbreviated to initials and DOI when available, and must not include unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Figures should include alternative text and be cited in numerical order, with multi-panel figures labeled (A), (B), (C), etc.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. At least five keywords are required, and any written or visual content produced by or edited using generative AI technology must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source.
References References must follow the journal reference style, list the first six authors followed by et al. with authors’ given names abbreviated to initials, include the DOI when available, and must not include unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables should be inserted at the end of the manuscript in editable format. Each figure and table must be cited in numerical order in the text, multi-panel figures should label panels as (A), (B), (C), etc., and all figures or images should include alternative text.
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Policy And Practice Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured as a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, sections on assessment of policy/guidelines options and implications, Actionable Recommendations, and Discussion. Manuscript must include at least five keywords and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure all in-text citations appear in the reference list and vice versa.
Figures & Tables Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. Each figure and table must be cited in numerical order in the text, and multi-panel figures should label panels as (A), (B), (C), and so on.
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Clinical Trial

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured and presented as a single paragraph. Abstract must include the clinical trial registry number, unique identifier, and the URL of the publicly accessible trial registry website.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion. Manuscript must include at least five keywords, a funding section, acknowledgement of any generative AI use in the acknowledgements and methods section if applicable, and a contribution to the field statement.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Figures and tables must be cited in numerical order in the text, and multi-panel figures must use panel labels such as (A), (B), and (C).
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured as a single paragraph, for example following the IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should be organized as Abstract, Introduction, subject-relevant subsections, and Discussion, and should discuss different schools of thought or controversies, current research gaps, and potential future developments in the field. Manuscript must include at least five keywords and any use of written or visual generative AI content must be acknowledged in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References References must use the journal style, list the first six authors followed by et al. with authors’ given names abbreviated to initials, include DOIs when available, and Mini Review articles must not cite unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Mini Review articles may include no more than 2 figures and/or tables in total. Figures must be submitted individually with captions at the end of the manuscript, while tables should be inserted at the end of the manuscript in editable format. Figure panels should be labeled (A), (B), (C), etc., and each table and figure must be cited in numerical order in the text.
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Case Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should be organized as Abstract, Introduction, Case description, a figure or table presenting a timeline of the episode of care, Diagnostic assessment with details on the therapeutic intervention, follow-up and outcomes, Discussion, and Patient perspective. The title must be formatted as "Case Report: 'area of focus'", at least five keywords are required, the first page must state the manuscript word count and number of figures and tables, and any use of generative AI content must be disclosed in the acknowledgements and methods where applicable with the tool name, version, model, and source.
References References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure all in-text citations appear in the reference list and vice versa.
Figures & Tables Case Reports may include no more than 4 display items in total, including figures, tables, or videos. Figures must be submitted individually and captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. The manuscript should include a figure or table showing a timeline with relevant data from the episode of care.
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Community Case Study

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 5,000 words. Manuscript should be organized as Abstract, Introduction, Context, Detail to understand key programmatic elements, Discussion sharing practical implications and lessons learned for future applications, and Acknowledgment of any conceptual or methodological constraints. Manuscript must include at least five keywords and disclose any use of generative AI in the acknowledgements and, if applicable, the methods section, including the name, version, model, and source of the tool.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Manuscript may contain no more than 5 figures and tables in total. Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Each figure and table must be cited in numerical order in the text, and multi-panel figures must label panels as (A), (B), (C), and so on.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured as a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 4,000 words. Manuscript should follow the format Abstract, Introduction, Method, Results, Discussion. At least five keywords are required, and any use of generative AI content must be acknowledged in the acknowledgements section and in the Methods section if applicable with the tool name, version, model, and source.
References References must follow the journal reference style and list the first six authors followed by et al., with author given names abbreviated to initials and DOI included when available.
Figures & Tables No more than four figures and/or tables are permitted. Figures must be submitted individually with captions placed at the end of the manuscript, and tables should be inserted at the end of the manuscript in editable format. Each figure and table must be cited in numerical order in the text, and multi-panel figures should use panel labels such as (A), (B), and (C).
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Technology And Code

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured and presented as a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, Method including any code description, Results including examples of use and limitations, and Discussion including scalability and limitations. Manuscript must include the project link, operating system, programming language, any restrictions for non-academic use, and an acknowledgment section and methods section disclosure naming the generative AI tool, version, model, and source if such technology was used.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
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Fair² Data

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured, for example according to the IMRAD format, and presented as a single paragraph.
Manuscript Fair² Data articles must not exceed 12,000 words. Manuscript must be organized by headings and subheadings. At least five keywords are required, a 200-word scope statement and a contribution to the field statement must be provided, and any use of generative AI must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source listed.
References References must include the first six authors followed by et al., use author initials for given names, include the DOI when available, and ensure all in-text citations appear in the reference list and vice versa.
Figures & Tables Fair² Data articles may include up to 15 figures or tables. Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables should be inserted at the end of the manuscript in editable format. Figures or images must include alternative text, each figure and table must be mentioned in numerical order in the text, and multi-panel figures should label panels as (A), (B), (C), (D), etc.
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Recent Publications

Impact of anatomic complexity of congenital heart disease on growth retardation: a large retrospective cohort study

Xi Yang, Siyu Liang, Xin Tang, Yutong Liu, Linyao Wang, Shi Chen, Hanze Du, Zengren Zhao, Hui Pan, Huijuan Ma

10.3389/fcvm.2026.1907307
View Publication

Multiparametric CMR evaluation of myocardial remodeling in dystrophinopathy

Wenting Luo, Jia Liu, Jie Wang, Yun Yuan, Jianxiu Lian, Wei Li, Shouyi Wei, Xiaofeng Qin, Wei Ma, Jianxing Qiu

10.3389/fcvm.2026.1935273
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Clinical characteristics of gut microbiota translocation after acute myocardial infarction and its impact on prognosis

JunXiang Liu, DongLin Song, Yi Yuan, HaiYing Sun, GuoHong Yang

10.3389/fcvm.2026.1890161
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Label-efficient cross-population transfer learning for electrocardiographic risk stratification: evaluation across German, Chinese and US cohorts

Yan Wang, Yan Lu

10.3389/fcvm.2026.1928354
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Sex differences in leptin levels but not in the leptin response to sacubitril/valsartan in patients with heart failure with reduced ejection fraction

Zornitsa Shomanova, Bernhard Ohnewein, Dilvin Semo, Vera Paar, Tobias Fröhling, Jürgen R. Sindermann, Uta C. Hoppe, Michael Lichtenauer, Maciej Zechowicz, Lukas J. Motloch, Rudin Pistulli

10.3389/fcvm.2026.1922853
View Publication

Frequently asked questions

How long does it take to publish?

Average of 90 days from submission to acceptance and 12 days from acceptance until the final typeset document.

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Is a cover letter required?

A traditional cover letter is not accepted. Authors must instead provide a 200-word contribution-to-the-field statement during submission.

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What are the publication costs?

Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles. APCs are charged for articles that pass peer review and are accepted for publication.

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Research Topics

Cardiovascular Function and Risk Factors Cardiac Valve Diseases and Treatments Atrial Fibrillation Management and Outcomes Cardiac Imaging and Diagnostics Aortic Disease and Treatment Approaches Coronary Interventions and Diagnostics Cardiac Arrhythmias and Treatments Heart Failure Treatment and Management Acute Myocardial Infarction Research Cardiac electrophysiology and arrhythmias Cardiac Structural Anomalies and Repair Congenital Heart Disease Studies Cardiovascular Disease and Adiposity Cardiac pacing and defibrillation studies Cardiac Fibrosis and Remodeling Mechanical Circulatory Support Devices Infective Endocarditis Diagnosis and Management Aortic aneurysm repair treatments Atherosclerosis and Cardiovascular Diseases Cardiomyopathy and Myosin Studies Cardiac and Coronary Surgery Techniques Diabetes, Cardiovascular Risks, and Lipoproteins Cardiovascular Health and Disease Prevention Pulmonary Hypertension Research and Treatments Lipoproteins and Cardiovascular Health