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Frontiers in Aging Neuroscience

Frontiers in Aging Neuroscience publishes research on the mechanisms of central nervous system aging and age-related neural disease, with a focus on aging neuroscience and related areas in geriatrics and gerontology.

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Subject Geriatrics & Gerontology, Neurosciences
Impact Factor 4.5
Quartile Q1
Open Access Type Open
ISSN 1663-4365
eISSN 1663-4365
Invitation Only No
Cost Range A-Type Articles: CHF 3,150; B-Type Articles: CHF 2,500; C-Type Articles:

Submission Instructions

Frontiers in Aging Neuroscience accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion. Manuscript must include at least five keywords and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure every in-text citation appears in the reference list and vice versa.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. Figures and tables must be cited in numerical order in the text, and all figures or images must include alternative text.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Systematic Review must clearly define the research question in terms of population, interventions, comparators, outcomes, and study designs (PICOS). Manuscript must include funding information and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the name, version, model, and source of the technology.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, include only published or accepted articles, and exclude unpublished material, submitted manuscripts, and personal communications.
Figures & Tables Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must be a structured single paragraph. The manuscript format requires an Abstract section.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. The manuscript must include at least five keywords, indicate the manuscript word count and number of figures and tables on the first page, and acknowledge any use of generative AI in the acknowledgements section and in Methods if applicable with the tool name, version, model, and source.
References References and citations must follow either Harvard or Vancouver style. References must include all in-text citations and vice versa, list the first six authors followed by et al. with authors’ given names abbreviated to initials, include the DOI when available, and must not include unpublished material or personal communications.
Figures & Tables Figures must be submitted individually and tables must be inserted at the end of the manuscript in editable format. Figure captions must be placed at the end of the manuscript, tables must not be submitted as figures, and all figures or images must include alternative text.
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion, and it must discuss different schools of thought or controversies, current research gaps, and potential future developments in the field. At least five keywords are required, and any use of generative AI for written or visual content must be disclosed in the acknowledgments section and in the methods section if applicable with the tool name, version, model, and source.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al. with authors’ given names abbreviated to initials and DOI included when available, and Mini Reviews must not cite unpublished material, including submitted manuscripts or personal communications.
Figures & Tables Mini Review articles may include no more than 2 figures and tables in total. Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Alternative text is required for all figures or images.
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Data Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following the IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must be organized as Introduction, methods used to collect the data including the data collection period, filters applied, and guidance on interpreting and reusing the dataset, some analysis of the data, and relevant subsections, and it must not include Results or Discussion sections. Manuscript must include the dataset name, the database or repository where the dataset was submitted, the confidential peer-review link to the dataset that will be updated to the public link before publication, at least five keywords, and an acknowledgment describing any generative AI use with the tool name, version, model, and source.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al. when applicable, abbreviate given names to initials, include the DOI when available, and ensure every in-text, figure, or table citation appears in the reference list and vice versa.
Figures & Tables Manuscript may contain no more than 2 figures and/or tables. Figures must be submitted individually and captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph.
Manuscript Manuscript must not exceed 4,000 words. Manuscript must be organized as Abstract, Introduction, Method, Results, and Discussion. Manuscript must include at least five keywords and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the tool name, version, model, and source.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure every in-text citation appears in the reference list and vice versa.
Figures & Tables Brief Research Report articles may include no more than 4 figures and tables in total. Figures must be submitted individually and captions placed at the end of the manuscript, while tables must be inserted at the end of the manuscript in editable format. All figures and images must include alternative text and each figure or table must be cited in numerical order in the text.
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Technology And Code

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured and included as part of the required article format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract; Introduction; Method including any code description; Results including examples of use and limitations; and Discussion including scalability and limitations. Manuscript must include a project link, the operating system, the programming language, any restrictions for non-academic use, and acknowledgment details for any generative AI use in the acknowledgements section and methods section if applicable.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables should be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
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Fair² Data

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized by headings and subheadings. At least five keywords are required, the first page must state the manuscript word count and number of figures and tables, and any use of generative AI for written or visual content must be acknowledged in the acknowledgements section and in the methods section if applicable with the tool name, version, model, and source.
References References and citations must follow either Harvard or Vancouver style. References must list the first six authors followed by et al. when applicable, abbreviate given names to initials, include the DOI when available, and ensure every in-text citation appears in the reference list and vice versa.
Figures & Tables A maximum of 15 figures or tables is permitted. Figures must be submitted individually and figure captions and tables must be placed at the end of the manuscript, with tables inserted in editable format. All figures or images must include alternative text, each figure and table must be cited in numerical order in the text, multi-panel figures must use labels such as (A), (B), (C), and individual figures must not exceed one page in length.
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Recent Publications

Microbial metabolites as modulators of gut–brain communication in neurodegeneration: from intestinal sensing to disease initiation and progression

Xi Liu, Sirui Wang, Wei Long, Xinyue Tan, Wanlin Li, LiChen Gao

10.3389/fnagi.2026.1926883
View Publication

Increased LINE-1 expression is associated with neuronal gene network downregulation in the aged mouse prefrontal cortex

Shinya Fujii, Chu Guo, Yutaka Nakachi, Mohammad Mustakim Billah, Yuko Imamura, Emi Kiyota, Miki Bundo, Kazuya Iwamoto

10.3389/fnagi.2026.1961301
View Publication

Editorial: The role of neurotransmitters: from normal aging to age-related diseases, volume II

Yan Zhou, Xiaodan Pan, Yitong Cao, Xuntao Yin

10.3389/fnagi.2026.2015252
View Publication

Editorial: Decoding the gut-brain axis: implications for neurodegenerative disease therapies

R. M. Damian Holsinger

10.3389/fnagi.2026.2015896
View Publication

Systems biology prioritizes drug candidates for an interferonresponse-high monocyte state in idiopathic normal pressure hydrocephalus

Md. Masudul Haque, Jongwan Bae, Irin Sultana Nila, Kyunghun Kang, Janghyeok Yoon, Sohee Kim, Ki-Su Park

10.3389/fnagi.2026.1971059
View Publication

Frequently asked questions

How long does it take to publish?

Average of 90 days from submission to acceptance and 12 days from acceptance to the final typeset document.

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Is a cover letter required?

A traditional cover letter is not permitted. Authors must prepare a 200-word contribution-to-the-field statement during submission.

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What are the publication costs?

Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles. APCs apply to articles that pass peer review and are accepted for publication. Full or partial institutional support and discounts for eligible authors may be available.

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Research Topics

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Functional Brain Connectivity Studies Parkinson's Disease Mechanisms and Treatments Neuroinflammation and Neurodegeneration Mechanisms Neurological Disease Mechanisms and Treatments Advanced Neuroimaging Techniques and Applications Neurological disorders and treatments Balance, Gait, and Falls Prevention EEG and Brain-Computer Interfaces Transcranial Magnetic Stimulation Studies Neuroscience and Neuropharmacology Research Tryptophan and brain disorders Neural and Behavioral Psychology Studies Intensive Care Unit Cognitive Disorders Neural dynamics and brain function Stroke Rehabilitation and Recovery Advanced MRI Techniques and Applications Memory and Neural Mechanisms Acute Ischemic Stroke Management Hearing Loss and Rehabilitation Intracerebral and Subarachnoid Hemorrhage Research Vestibular and auditory disorders Mitochondrial Function and Pathology Nuclear Receptors and Signaling

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