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CNS Neuroscience & Therapeutics

CNS Neuroscience & Therapeutics is an open access journal publishing research related to the central nervous system, clinical pharmacology, drug development and novel methodologies for drug evaluation. The journal focuses on neurological and psychiatric diseases such as stroke, Parkinson’s disease, Alzheimer’s disease, depression, schizophrenia, epilepsy, and drug abuse.

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Impact Factor 5
Quartile Q1
Open Access Type Open
ISSN 1755-5930
eISSN 1755-5949
Invitation Only No
Cost Range $4,550 USD / £3,450 GBP / €3,900 EUR APC for accepted and published articles; waived for Editorial Commentary and Clinical Guidelines.

Submission Instructions

CNS Neuroscience & Therapeutics accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter A cover letter is required. Cover letter must state that all authors contributed significantly and agree with the manuscript content and its submission to the journal.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must use the headings Aims, Methods, Results, and Conclusion.
Manuscript Manuscript must not exceed 4000 words including the abstract but excluding references, tables, and figures. Main text must be organized as Introduction, Methods, Results, Conclusion, Acknowledgment, Disclosure, and References. Manuscript must include four to eight key words and a disclosure statement under the heading 'Disclosure' after 'Acknowledgement' and before 'References'.
References References may include up to 60 entries. References must follow Vancouver style. References must be numbered consecutively in order of appearance, cited with Arabic superscript numerals, and list the first 3 authors followed by et al when there are more than 6 authors.
Figures & Tables A maximum of 6 figures and tables combined is allowed. Figures must be supplied as separate files, and tables must appear on separate pages with figure legends provided as a complete list in the text. Figures and tables must be numbered consecutively in Arabic numerals and accompanied by concise, comprehensive legends.
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Reviews

Cover Letter A cover letter is required. Cover letter must confirm that all authors contributed significantly, agree with the manuscript content, and agree to submission.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 4000 words including the abstract but excluding references, tables, and figures. Manuscript must be arranged as title page, abstract and key words, text, acknowledgments, disclosure, references, tables, and figure legends, with the main body formatted as Introduction, Methods, Results, Conclusion, Acknowledgment, Disclosure, References, and when relevant Supplementary Material. Manuscript must include four to eight key words and a disclosure statement in the body under the heading 'Disclosure' placed after 'Acknowledgement' and before 'References'.
References Reviews may include up to 150 references. References must follow Vancouver style. References must be numbered consecutively in order of appearance with Arabic superscript in-text citations, and if a reference has more than six authors only the first three should be listed followed by 'et al.'
Figures & Tables Reviews must include at least 1 and no more than 3 figures and tables. Figures must be supplied as separate files, while tables and figure legends must be included in the manuscript. Figures and tables must be numbered consecutively in Arabic numerals and each must have a legend.
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Meta-Analyses

Cover Letter A cover letter is required. Cover letter must state that all authors contributed significantly, agree with the manuscript content, and agree to submission to the journal.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must state the main problem, methods, results, and conclusions.
Manuscript Manuscript must not exceed 4000 words including the abstract but excluding references, tables, and figures. Main text must be formatted as Introduction, Methods, Results, Conclusion, Acknowledgment, Disclosure, References, and when relevant Supplementary Material. Manuscript must include four to eight key words and a disclosure statement in the body under the heading 'Disclosure'.
References There is no maximum reference limit. References must follow Vancouver style. References must be numbered consecutively in order of appearance with Arabic superscript in-text citations, and if a reference has more than 6 authors only the first 3 should be listed followed by 'et al'.
Figures & Tables Figures must be supplied as separate files, and tables must be placed on separate pages with legends above. Figures and tables must have concise, comprehensive legends, and figures must be numbered in Arabic numerals and cited consecutively in the text.
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Clinical Guidelines

Cover Letter A cover letter must be included with the submission. The cover letter must confirm that all authors contributed significantly and approve the manuscript content and its submission.
Abstract An abstract is required. The abstract must not exceed 250 words.
Manuscript The manuscript must not exceed 5000 words including the abstract but excluding references, tables, and figures. The manuscript must be presented in the order title page, abstract and key words, text, acknowledgments, disclosure, references, tables, and figure legends. The manuscript must include four to eight key words and a disclosure statement in the body under the heading 'Disclosure' placed after 'Acknowledgement' and before 'References'.
References There is no maximum reference limit. References must follow Vancouver style. References must be numbered consecutively in order of appearance, cited in the text with Arabic superscript numerals, and if there are more than six authors only the first three names should be listed followed by 'et al'.
Figures & Tables Figures must be supplied as separate files, and tables must be placed on separate pages with their legends above. Figures and tables must have legends, figure legends must be provided as a complete list in the text, and figures and tables must be numbered consecutively in Arabic numerals.
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Letters To The Editor

Cover Letter A cover letter must be included with the submission. The cover letter must confirm that all authors contributed significantly and agree with the manuscript content and its submission.
Abstract Abstract is not required for Letters To The Editor.
Manuscript Letters To The Editor must not exceed 1000 words. Letters To The Editor must offer perspective on content published in the journal or information critical to a certain area and must reference the original source.
References Letters To The Editor may include up to 10 references. References must follow Vancouver style. References must be numbered consecutively in order of appearance using Arabic superscript numerals, and if there are more than 6 authors only the first 3 should be listed followed by et al.
Figures & Tables Letters To The Editor may include up to 2 figures and tables. Figures must be supplied as separate files. Figure and table legends are required.
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Letter To The Journal

Cover Letter A cover letter is required in the submission system. Cover letter must state that all authors contributed significantly and agree with the manuscript content and its submission.
Abstract An abstract is not required.
Manuscript Manuscript must not exceed 1000 words.
References References may include up to 10 entries. References must follow Vancouver style. References must be numbered consecutively in order of appearance with Arabic superscript numerals in the text, and if there are more than 6 authors list the first 3 followed by et al.
Figures & Tables A maximum of 2 figures and tables may be included. Figures must be supplied as separate files. Figures and tables must have legends.
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Recent Publications

Admission Phenotype Clarifies the Apparent Prognostic Contrast Between TOAST Etiologic Subtypes in Large‐Core Anterior‐Circulation Large‐Vessel Occlusion

Chengsong Yue, Shihai Yang, Xiongxiong Hou, Jingfu Ma, Xu Xu, Xiaolei Shi, Linyu Li, Jie Yang, Changwei Guo, Jiaxing Song, Wenjie Zi, Rongzong Li

10.1002/cns.71029
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Metabolic Signatures and Diagnostic Strategies for Different Types of Encephalitis

Yue Cui, Haitian Nan, Zhen Wang, Daiquan Gao, Hong Ye, Yunzhou Zhang, Junjie Li, Weibi Chen, Lin Wang, Jing Zhang, Liyong Wu

10.1002/cns.71014
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Oral Lysozyme Attenuates Neuroinflammation and Brain Injury After Traumatic Brain Injury Through Gut Microbiota‐Dependent Reprogramming of Tryptophan Metabolism

Zhuoying Du, Haijun Yao, Caihua Xi, Qiang Yuan, Pengfei Fu, Jin Hu, Gang Wu, Weijian Yang

10.1002/cns.71025
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Personality Traits and Their Association With Medication Non‐Adherence in Patients With Multiple Sclerosis

Pegah Mashhadiakbar, Michael Hecker, Niklas Frahm, Julia Baldt, Bassel Barhoum, Katja Burian, Silvan Elias Langhorst, Janina Meißner, Barbara Streckenbach, Avinash Mohnish Suntah, Jörg Richter, Felicita Heidler, Uwe Klaus Zettl

10.1002/cns.71020
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Supraspinal Circuit Mechanisms Underlying Itch Processing

Yuncheng Luo, Hao‐Di Tang, Ping Liao, Ruotian Jiang

10.1002/cns.71022
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Frequently asked questions

How long does it take to publish?

Median submission to first decision is 21 days, median submission to acceptance is 133 days, and median acceptance to publication is 16 days.

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Is a cover letter required?

A cover letter should be included in the Cover Letter field of the submission system. It must acknowledge that all authors contributed significantly and state that all authors agree with the manuscript content and its submission to CNS Neuroscience & Therapeutics.

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What are the publication costs?

APC: $4,550 USD / £3,450 GBP / €3,900 EUR for accepted and published articles. Editorial Commentary and Clinical Guidelines are waived.

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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms Neuroscience and Neuropharmacology Research Alzheimer's disease research and treatments Parkinson's Disease Mechanisms and Treatments Functional Brain Connectivity Studies Neurological disorders and treatments Neurogenesis and neuroplasticity mechanisms Neurological Disease Mechanisms and Treatments Epilepsy research and treatment Acute Ischemic Stroke Management Nerve injury and regeneration Intracerebral and Subarachnoid Hemorrhage Research Tryptophan and brain disorders Glioma Diagnosis and Treatment Transcranial Magnetic Stimulation Studies Dementia and Cognitive Impairment Research Neurotransmitter Receptor Influence on Behavior Traumatic Brain Injury and Neurovascular Disturbances Pain Mechanisms and Treatments Cholinesterase and Neurodegenerative Diseases Barrier Structure and Function Studies Intensive Care Unit Cognitive Disorders Anesthesia and Neurotoxicity Research Autophagy in Disease and Therapy Amyotrophic Lateral Sclerosis Research