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Translational Neurodegeneration

Translational Neurodegeneration is an open access, peer-reviewed journal that covers research, therapeutics and education for all aspects of neurodegenerative diseases. It creates an interface between basic, translational, and clinical research and is affiliated with Ruijin Hospital.

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Subject Neurosciences
Impact Factor 15.2
Quartile Q1
Open Access Type Open
ISSN 2047-9158
eISSN 2047-9158
Invitation Only Yes
Cost Range APC: £2290.00 GBP / $3090.00 USD / €2690.00 EUR; Research Highlight or Correspondence APC: £1590.00 GBP / $2180.00 USD / €1890.00 EUR.

Submission Instructions

Translational Neurodegeneration is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Research

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any journal policy issues, declare any potential competing interests, confirm all authors approved submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Methods, Results, Conclusions, and Trial registration.
Manuscript Manuscript must include Background, Methods, Results, Discussion, Conclusions, and a Declarations section. Manuscript must include three to ten keywords, include all prescribed Declarations subsections with 'Not applicable' where irrelevant, and document any use of a Large Language Model in the Methods section or another suitable section if no Methods section is available.
References References must follow Vancouver style. Only published or in-press articles, clinical trial registration records, abstracts, and public preprints may be cited, unpublished abstracts/data and personal communications must be excluded from the reference list, and web links or URLs must be numbered and included in the reference list in full with site title, URL, and access date.
Figures & Tables Tables shorter than one page may be placed within the manuscript, tables longer than one page may be placed at the end of the text file with callouts in the text, and figure titles and legends must appear in the main manuscript while figure files are uploaded separately. Figures must be numbered in text order and multipart figures submitted as single composite files, while tables must be numbered in sequence and created using the word processor's table function rather than embedded as figures or spreadsheet files.
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Review

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include Background, Main Body, and a short Conclusion.
Manuscript Manuscript must include Background, Main text, Conclusions, and a Declarations section with all required subheadings. Review must include three to ten keywords and all Declarations subheadings must be present with 'Not applicable' used where a section is not relevant.
References References must follow Vancouver style. Web links and URLs must be cited with a reference number and included in the reference list, and unpublished abstracts, unpublished data, and personal communications must not appear in the reference list.
Figures & Tables Tables shorter than one page may be placed in the manuscript at the appropriate location, tables longer than one page may be placed at the end of the document, and figures must be uploaded separately in the order cited. Multi-panel figures must be submitted as a single composite file, figure titles and legends must be provided in the manuscript rather than the graphic files, and tables must not be embedded as figures or spreadsheet files.
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Correspondence

Cover Letter Cover letter is required. Cover letter must explain why the manuscript should be published, explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, and confirm the content has not been published or submitted elsewhere.
Abstract Abstract is not required.
Manuscript Correspondence must not exceed 1500 words including references, figures and tables. Correspondence must have no abstract and must include a Declarations section. Declarations must include the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information (optional), with 'Not applicable' used when a subsection is not relevant.
References References must follow Vancouver style. Web links and URLs must be assigned a reference number and included in the reference list rather than in the text.
Figures & Tables Correspondence must have no more than 1 display item (figure or table). Tables shorter than one page may be placed within the manuscript, while larger tables may be placed at the end of the document, and figures must be uploaded separately. Multi-panel figures must be submitted as a single composite file, and figure titles and legends must be provided in the main manuscript rather than in the graphic file.
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Research Highlight

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, confirm the content has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract Abstract must not be included.
Manuscript Main text must be no more than 1000 words, excluding the title and references. Manuscript does not require subsections and must include a title page with the title, all authors’ full names and institutional addresses, and the corresponding author indicated. Manuscript must include a Declarations section with the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and optionally Authors' information, with 'Not applicable' used for any non-relevant section, and must provide a list of abbreviations if abbreviations are used.
References References must not exceed 10. References must use Vancouver style. Web links and URLs must be cited with a reference number and included in the reference list in full with the site title, URL, and access date, and unpublished abstracts, unpublished data, and personal communications must not be included in the reference list.
Figures & Tables Manuscript may include one figure. Tables shorter than one page may be placed within the manuscript, while tables longer than one page may be placed at the end of the document and must be cited in the text where they should appear. Figures must be numbered in order of first mention and uploaded in that order, with titles and legends provided in the main manuscript rather than in the graphic file.
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Recent Publications

PCSK9 inhibitors in neurodegenerative disorders: mechanisms, therapeutic potential, and clinical implications

Jia Dong James Wang, Andrea York Tiang Teo, Bin Xiao, Yinxia Chao, Zhi Dong Zhou, Brendan Jen-Wei Tan, Ling-Ling Chan, Elvira Rosalie, Eng-King Tan

10.1186/s40035-026-00568-y
View Publication

The mitophagy-inflammasome axis: a shared pathological hub in Alzheimer’s and Parkinson’s diseases

Wei Long, Mengqin Yuan, Sirui Wang, Xinyue Tan, Li-Chen Gao

10.1186/s40035-026-00578-w
View Publication

Cholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington’s disease

Monica Favagrossa, Alice Passoni, Marta Valenza, Daria Di Prisco, Giulia Birolini, Michela Villa, Andrea Scolz, Laura Pasetto, Valentina Bonetto, Chiara Zuccato, Caterina Mariotti, Renzo Bagnati, Elena Cattaneo, Laura Colombo, Mario Salmona

10.1186/s40035-026-00569-x
View Publication

Brain insulin resistance as a driver of proteinopathy in neurodegeneration: from cell-type-specific mechanisms to targeted therapeutics

Man Xiang, Si-Yu Cao, Xue-Heng Sun, Jing-Wen Hu, Ming-Zhe Lv, Jia-Yi Li, Wen Li

10.1186/s40035-026-00573-1
View Publication

Neuroinflammation in Alzheimer’s and Parkinson’s diseases: pathogenic mechanisms and therapeutic strategies

Qin-qin Wang, Qing-qing Sun, Yong-shun Guo, Shu Yin, Jia-wei Zhou

10.1186/s40035-026-00571-3
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 11 days.

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Is a cover letter required?

A cover letter is required. It should explain why the manuscript should be published in Translational Neurodegeneration, address any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the submission, confirm that the manuscript has not been published or submitted elsewhere, and name the special issue if applicable. Authors may also suggest preferred and non-preferred peer reviewers in the cover letter.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £2290.00 GBP / $3090.00 USD / €2690.00 EUR. The APC for a Research Highlight or Correspondence is £1590.00 GBP / $2180.00 USD / €1890.00 EUR.

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Research Topics

Parkinson's Disease Mechanisms and Treatments Alzheimer's disease research and treatments Neurological disorders and treatments Amyotrophic Lateral Sclerosis Research Neuroinflammation and Neurodegeneration Mechanisms Dementia and Cognitive Impairment Research Genetic Neurodegenerative Diseases Mitochondrial Function and Pathology Neurogenesis and neuroplasticity mechanisms Neurological diseases and metabolism Nerve injury and regeneration Tryptophan and brain disorders Neurogenetic and Muscular Disorders Research Autophagy in Disease and Therapy Nuclear Receptors and Signaling Neuroscience and Neuropharmacology Research Cellular transport and secretion Cholinesterase and Neurodegenerative Diseases Extracellular vesicles in disease Pluripotent Stem Cells Research Olfactory and Sensory Function Studies RNA regulation and disease Functional Brain Connectivity Studies Lysosomal Storage Disorders Research Transcranial Magnetic Stimulation Studies

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