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Frontiers In Toxicology

Frontiers in Toxicology is a multidisciplinary journal that explores the effects of toxicants from molecular to population level and presents research on the adverse effects of substances, particles and mixtures on living organisms.

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Subject Toxicology
Impact Factor 4.6
Quartile Q1
Open Access Type Open
eISSN 2673-3080
Invitation Only No
Cost Range A-Type Articles: CHF 2,695; B-Type Articles: CHF 2,195.

Submission Instructions

Frontiers In Toxicology accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Original Research articles must not exceed 12,000 words. Original Research articles should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion. Manuscripts must include 5 to 8 keywords, indicate the number of words and figures and tables on the first page, and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable with the name, version, model, and source.
References References must include only published or accepted works, list the first six authors followed by et al. with author given names abbreviated to initials and DOI when available, and ensure all in-text citations appear in the reference list and vice versa.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted at the end of the manuscript and not submitted as figures. Each figure and table must be cited in numerical order in the text, multi-panel figures must use labels such as (A), (B), (C), and all figures or images should include alternative text.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Systematic Reviews should clearly define the research question in terms of population, interventions, comparators, outcomes, and study designs (PICOS). Funding information must be included in the manuscript, and any use of generative AI must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source of the tool.
References References must provide the first six authors followed by et al. and include the DOI when available, and unpublished material including submitted manuscripts and personal communications must not be included.
Figures & Tables Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables must be directly inserted at the end of the manuscript. Each figure and table must be mentioned in the text in numerical order.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, subsections relevant to the subject, and Discussion. Manuscript must include 5 to 8 keywords, indicate the number of words and figures and tables on the first page, and acknowledge any generative AI use in the acknowledgements section and in the methods section if applicable with the name, version, model, and source.
References References must list the first six authors followed by et al. and include the DOI when available, and review articles must not cite unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be directly inserted at the end of the manuscript in editable format. Each figure and table must be mentioned in the text in numerical order, and multi-panel figures must use labels such as (A), (B), (C), and (D).
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. Manuscript should discuss different schools of thought or controversies, current research gaps, potential future developments, include 5 to 8 keywords, and acknowledge any generative AI use in the acknowledgements and methods if applicable.
References References must follow the journal's reference style, list the first six authors followed by et al. with DOI when available, and must not include unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Manuscript may contain no more than 2 figures and/or tables. Figures must be submitted individually and figure captions placed at the end of the manuscript, while tables must be directly inserted into the manuscript at the end. Figures must be cited in numerical order and multi-panel figures labeled (A), (B), (C), etc., while tables must be editable and not submitted as figures.
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Policy And Practice Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, sections on assessment of policy or guidelines options and implications, Actionable Recommendations, and Discussion. Manuscript must include 5 to 8 keywords, and any use of generative AI for written or visual content must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source of the tool.
References References must follow the journal's reference style, list the first six authors followed by et al. with authors' given names abbreviated to initials, include DOIs when available, and ensure every in-text citation appears in the reference list and vice versa.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted into the manuscript and placed at the end. Each figure and table must be cited in numerical order, multi-panel figures must use labels such as (A), (B), and large tables spanning several pages must be provided as supplementary material.
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Case Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Title must follow the format "Case Report: 'area of focus'" and the manuscript must be organized by headings and subheadings. Manuscript must include 5 to 8 keywords, and any use of generative AI technology must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source.
References References must follow the journal's reference style, list the first six authors followed by et al. when applicable, abbreviate given names to initials, include the DOI when available, and include only published or accepted works.
Figures & Tables Case Report articles may contain no more than 4 display items in total, including figures, tables, or videos. Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted directly into the manuscript at the end in editable format. Each figure and table must be cited in numerical order in the text, and multi-panel figures must use labeled panels such as (A), (B), and (C).
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Community Case Study

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be included as a single structured paragraph.
Manuscript Manuscript must not exceed 5,000 words. Manuscript should be organized as Abstract; Introduction describing the nature of the problem being addressed and rationale for the proposed innovation; Context setting and population in which the innovation occurs; Detail to understand key programmatic elements; Discussion sharing practical implications and lessons learned for future applications; and Acknowledgment of any conceptual or methodological constraints. Manuscript must include 5 to 8 keywords, indicate the number of words and figures/tables on the first page, and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable.
References References must follow the journal's reference style, list the first six authors followed by et al. with authors' given names abbreviated to initials, include DOIs when available, and include only published or accepted works in the reference list.
Figures & Tables Manuscript may contain no more than 5 figures and/or tables in total. Figures must be submitted individually with captions at the end of the manuscript, while tables must be directly inserted at the end of the manuscript and not submitted as figures. Each figure and table must be cited in numerical order in the text, and multi-panel figures must use labeled panels such as (A), (B), (C), and (D).
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Data Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should be organized as Introduction; Methods used to collect the data, including the data collection period, filters applied, and information on dataset interpretation and reuse; some analysis of the data without reporting results of any single study or group of studies; and relevant subsections, with no Results or Discussion sections. Manuscript must include the dataset name, the database or repository where the dataset has been submitted, the confidential peer review link to the dataset updated to a public link before publication, at least five and no more than eight keywords, and an acknowledgement of any generative AI use in the acknowledgements section and in the methods section if applicable including the name, version, model, and source.
References References must adhere to the journal's reference style, list the first six authors followed by et al. with authors' given names abbreviated to initials and DOI when available, include only works that are published or accepted, use 'in press' for accepted unpublished works, and ensure all in-text citations and reference-list entries correspond exactly.
Figures & Tables Manuscript may contain no more than 2 figures and tables in total. Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted at the end of the manuscript in editable format and not submitted as figures. Each figure and table must be cited in numerical order in the text, multipart figure panels must be labeled (A), (B), (C), etc., and all figures or images should include alternative text.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured.
Manuscript Manuscript must not exceed 4,000 words. Manuscript should be organized as Abstract, Introduction, Method, Results, and Discussion. Manuscript must include 5 to 8 keywords, and any use of generative AI must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source of the tool.
References References must follow the journal's reference style, list the first six authors followed by et al. when applicable, abbreviate given names to initials, include DOIs when available, and include only works that are published or accepted.
Figures & Tables Manuscript may contain no more than 4 figures and tables in total. Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be directly inserted into the manuscript at the end. Each figure and table must be cited in numerical order in the text, and multipanel figures must use labeled panels such as (A), (B), and (C).
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Technology And Code

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Method including any code description, Results including examples of use and limitations, and Discussion including scalability and limitations. Manuscript must include a project link, the operating system, the programming language, any restrictions for non-academic use, and an acknowledgement of generative AI use in the acknowledgements section and in the methods section if applicable.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually and tables must be directly inserted into the manuscript. Figure captions must be placed at the end of the manuscript and table captions must be placed immediately before the table.
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Fair² Data

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Fair² Data articles are capped at 12,000 words. Manuscripts must be organized by headings and subheadings. The manuscript must acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the name, version, model, and source of the technology.
References References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and ensure all in-text citations appear in the reference list and vice versa.
Figures & Tables Fair² Data articles may include up to 15 figures or tables. Figures must be submitted individually, while tables must be directly inserted into the manuscript. Figure captions must be placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in an editable format.
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Recent Publications

Advancing chemical mixture toxicity assessment using advanced in vitro NAMs: current status and future perspectives

Hyunwoo Kim, Donghyeon Kim, Jinhee Choi

10.3389/ftox.2026.1757928
View Publication

Hyperbaric oxygen therapy for ischemic encephalopathy following occupational exposure to high-concentration toxic gases: two Case Reports

Yang Pang, Jiaojiao Yuan, Xu Yuan, Xiaomin Chai, Si Li

10.3389/ftox.2026.1782213
View Publication

Toxicological impacts of environmentally equivalent microplastics and cadmium co-exposure in tropical freshwater crab Sartoriana spinigera

Ananya Chakraborty, Upayan Anam, Tanmoy Gupta, Md. Khalid Saifullah, Gourab Chowdhury, Md. Selim Reza, Mohammad Moniruzzaman, Petra Schneider, Mohammed Mahbub Iqbal, Mohammad Amzad Hossain

10.3389/ftox.2026.1804866
View Publication

Micro- and nanoplastic exposure as an emerging risk factor for depressive-like phenotypes across species: a systematic review

Donato Morena, Damiano Marchesini, Monica La Greca, Letizia Biso, Matteo Lippi, Matteo Scopetti, Emanuela Turillazzi, Vittorio Fineschi

10.3389/ftox.2026.1817678
View Publication

Impact of liquid dosing and associated cell ‘drowning’ in a 3D human bronchial epithelial model used for protease exposure studies

Georgina Hopkins, David Sheffield, Hugh Barlow, Anja Lalljie, Stella Cochrane, Lucy C Fairclough

10.3389/ftox.2026.1781231
View Publication

Frequently asked questions

How long does it take to publish?

Average of 90 days from submission to acceptance and 12 days from acceptance until the final typeset document.

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Is a cover letter required?

A traditional cover letter is not allowed. Authors must prepare a 200-word contribution-to-the-field statement during submission.

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What are the publication costs?

Article processing charges are CHF 2,695 for A-Type Articles and CHF 2,195 for B-Type Articles. Institutional partnerships and support programs may provide full, partial, or discounted APC coverage.

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Research Topics

Effects and risks of endocrine disrupting chemicals Animal testing and alternatives Nanoparticles: synthesis and applications Carcinogens and Genotoxicity Assessment Microplastics and Plastic Pollution Toxic Organic Pollutants Impact Computational Drug Discovery Methods Air Quality and Health Impacts Immunotoxicology and immune responses Environmental Toxicology and Ecotoxicology 3D Printing in Biomedical Research Per- and polyfluoroalkyl substances research Pesticide Exposure and Toxicity Health, Environment, Cognitive Aging Heavy Metal Exposure and Toxicity Contact Dermatitis and Allergies Birth, Development, and Health Pharmaceutical and Antibiotic Environmental Impacts Pesticide and Herbicide Environmental Studies Graphene and Nanomaterials Applications Smoking Behavior and Cessation Poisoning and overdose treatments Forensic Toxicology and Drug Analysis Zebrafish Biomedical Research Applications Cannabis and Cannabinoid Research

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