Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Human & Experimental Toxicology

Human and Experimental Toxicology (HET) is an open access international peer reviewed journal dedicated to publishing original research papers and in-depth reviews covering functional, biochemical and structural disorders in toxicology, with an emphasis on timely high impact hypothesis driven research.

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Subject Toxicology

Impact Factor 3.2

Quartile Q2

Open Access Type Hybrid

ISSN 0960-3271

eISSN 1477-0903

Invitation Only No

Cost Range Article processing charges apply for hybrid open access journals, with possible institutional coverage, prepaid accounts, or affiliation-based discounts.

Submission Instructions

Human & Experimental Toxicology accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter A cover letter is required. Cover letter must explain why the manuscript is suitable for publication and disclose any third-party writing or editing assistance or submission by a non-author, if applicable.

Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must concisely state the purpose of the research, major findings, and conclusions.

Manuscript Manuscript must be organized as Title page, Summary (abstract) and keywords, Introduction, Methods, Results, Discussion, Acknowledgements, and References. Manuscript must include at least 5 keywords after the abstract, an Author Contributions section after the Acknowledgements, and a 'Statements and Declarations' section at the end of the article with all required subheadings including 'Not applicable' where relevant.

References References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and every reference list entry must have a corresponding in-text citation.

Figures & Tables Figures, charts, and tables created in Word should be included in the main text, while figures and other files created outside Word must be submitted separately with a placeholder in the text. Figures must be numbered consecutively, and tables must be labeled as tables with a number and title and be editable text rather than images.

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Review Articles

Abstract A summary abstract is required. Abstract must not exceed 200 words. Abstract must be structured.

Manuscript Review article must contain a summary, an introduction to the topic, a careful review of the relevant and current literature, conclusions of the reviewed literature, and recommendations if applicable. Manuscript must include at least 5 keywords after the abstract, an Author Contributions heading after the Acknowledgements section, and a section headed 'Statements and Declarations' after the Acknowledgements and Author Contributions sections with all required subheadings included, using 'Not applicable' where needed.

Figures & Tables Figures, charts, and tables created in Word should be included in the main text, while figures and other files created outside Word must be submitted separately with a placeholder note in the text for separately submitted figures. Figures must be numbered consecutively in the order cited, and tables must be editable text in Word rather than images.

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Mini-Reviews

Cover Letter A cover letter is required. Cover letter must indicate why the manuscript is suitable for publication and disclose any third-party writing or editing assistance or submission by someone not listed as an author, if applicable.

Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured.

Manuscript Mini-Reviews should be about 10 typewritten, double-spaced pages, including figures, figure legends, tables, and references. Manuscript should be structured into Title page, Summary (abstract) and keywords, Introduction, Methods, Results, Discussion, Acknowledgements, and References. Manuscript must include at least 5 keywords after the abstract, an Author Contributions heading after the Acknowledgements section, and a section headed 'Statements and Declarations' after the Acknowledgements and Author Contributions sections.

References References must follow the Sage Vancouver reference style. Mini-Reviews should follow the reference system used for Original Research articles.

Figures & Tables Figures, charts, and tables created in Word should be included in the main text, while figures and other files created outside Word must be submitted separately with a placeholder note in the running text. Mini-Reviews should follow the figure, figure legend, and table system used for Original Research articles.

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Full-Length Reviews

Cover Letter A cover letter is required. Cover letter must explain why the manuscript is suitable for publication and disclose any third-party writing/editing assistance or submission by a non-author if applicable.

Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured.

Manuscript Manuscript must not exceed 50 typewritten, double-spaced pages, including figures, figure legends, tables, and references. Manuscript should be organized into Title page, Summary (abstract) and keywords, Introduction, Methods, Results, Discussion, Acknowledgements, and References. Manuscript must include at least 5 keywords after the abstract, an Author Contributions section after the Acknowledgements, and a 'Statements and Declarations' section with all required subheadings, using 'Not applicable' where needed.

References References must follow Sage Vancouver style. Full-Length Reviews should use the same reference system as Original Research articles, and every in-text citation must correspond to a reference list entry and vice versa.

Figures & Tables Figures, charts, and tables created in Word should be embedded in the main text, while figures and other files created outside Word must be submitted separately with placeholder notes in the text. Full-Length Reviews should use the same figure, figure legend, and table system as Original Research articles, and figures must be numbered consecutively.

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Recent Publications

Ascorbate and alpha-tocopherol attenuate hepatorenal injury and modulate CYP2E1 and Nrf2 expression in rats exposed to herbalised alcoholic beverage

Temidayo Daniel Adeniyi, Akinpelu Moronkeji, Godwin Olawoyin Adunmo, Adetokunbo Adedotun Okunnuga, Olayinka Joshua Ajala, Abiodun Oyeleke, Puritan Chinonso Umeboro, Oluwatimilehin Kemisola Thomas

10.1177/09603271261442765

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TFAP2A activates the OCT4-induced epithelial-mesenchymal transition (EMT) by repressing ATOH8 to promote esophageal squamous cell carcinoma progression

Qiqi Zhang, Jiabin Wang, Jinchun Wang, Zhengyuan Xu

10.1177/09603271261420420

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“YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis”

10.1177/09603271261452720

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Retraction: Ginsenoside re suppresses high glucose-induced apoptosis of placental trophoblasts through endoplasmic reticulum stress-related CHOP/GADD153

10.1177/09603271261453113

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A new 1,4-dihydropyridine-based L-/T-type calcium channel inhibitor, provides in- vivo and silico cardioprotective effects in doxorubicin toxicity in rats

Oluwafemi Ezekiel Kale, Miyase Gözde Gündüz, Ifabunmi Oduyemi Osonuga, Olufunsho Awodele, Martins Ekor

10.1177/09603271261446916

View Publication

Frequently asked questions

How long does it take to publish?

Accepted articles can appear online within an average of 30 days after APC processing.

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Is a cover letter required?

A cover letter is required and should explain why the manuscript is suitable for publication. If third-party writing or editing assistance was used, or if submission is made by someone not listed as an author, this must also be stated in the covering letter.

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What are the publication costs?

Article processing charges apply for hybrid open access journals, with possible institutional coverage, prepaid accounts, or affiliation-based discounts.

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Research Topics

Pesticide Exposure and Toxicity Carcinogens and Genotoxicity Assessment Poisoning and overdose treatments Heavy Metal Exposure and Toxicity Drug-Induced Hepatotoxicity and Protection Effects and risks of endocrine disrupting chemicals Animal testing and alternatives Toxic Organic Pollutants Impact Trace Elements in Health Air Quality and Health Impacts Immunotoxicology and immune responses Genomics, phytochemicals, and oxidative stress Effects of Radiation Exposure Chemotherapy-induced organ toxicity mitigation Heme Oxygenase-1 and Carbon Monoxide Pharmacogenetics and Drug Metabolism Drug Transport and Resistance Mechanisms Environmental Toxicology and Ecotoxicology Glutathione Transferases and Polymorphisms Neuroscience and Neuropharmacology Research Alcohol Consumption and Health Effects Paraquat toxicity studies and treatments Forensic Toxicology and Drug Analysis Insect and Pesticide Research Pharmacological Effects and Toxicity Studies

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