JO

Journal of Biomedical Informatics

The Journal of Biomedical Informatics (JBI) is a methodology journal in biomedical informatics that publishes research on new methodologies and techniques with general applicability to real-world biomedical or clinical problems. The journal emphasizes novel informatics methods, comparison with current state-of-the-art approaches, and evaluation relevant to clinical practice, with topics including clinical decision support, patient safety, natural language processing, artificial intelligence and machine learning, knowledge representation for healthcare, translational bioinformatics, clinical research informatics, and clinical informatics.

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Subject Medical Informatics
Impact Factor 4.5
Quartile Q2
Open Access Type Hybrid
ISSN 1532-0464
eISSN 1532-0480
Invitation Only No
Cost Range USD 3530 APC for open access articles; no open access publication fee for subscription publication

Submission Instructions

Journal of Biomedical Informatics accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter A cover letter is required.
Abstract A structured abstract is required. Abstract must be 300 words or fewer. Abstract must be structured. Abstract headings must be Objective, Methods, Results, and Conclusion.
Manuscript Manuscript body must be 6000 words or fewer. Manuscript body must be organized as Introduction, Related Work, Methods, Results, Discussion, and Conclusion. Manuscript must include a graphical abstract, a Statement of Significance table at the end of the introduction with the headings Problem or Issue, What is Already Known, What this Paper Adds, and Who would benefit from the new knowledge in this paper in 150 words or fewer, keywords, a declaration of competing interest, and an AI declaration statement at the end of the manuscript immediately before the references if AI tools were used for manuscript preparation.
References References must be cited by number in square brackets. References must be numbered in the order of appearance and include author names, chapter or article titles, journal or book titles, year, and volume numbers, article numbers, or pagination where applicable.
Figures & Tables The combined total number of figures and tables must not exceed 8. Tables may be placed next to the relevant text or on separate pages at the end of the article, while figures and other artwork must be supplied as separate files. Tables must be editable text with captions and figures must have captions, and any generative AI-created image must be disclosed in the relevant image caption.
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Methodological Review

Cover Letter A cover letter is required.
Abstract A structured abstract is required. Abstract must be 300 words or fewer. Abstract must be structured. Abstract headings must be Objective, Methods, Results, and Conclusion.
Manuscript Manuscript body must be 6000 words or fewer. Manuscript must be structured as Introduction, Related Work, Methods, Results, Discussion, and Conclusion, and Methodological Reviews must specify the systematic methods including the exact search terms and the resources searched. The manuscript must include a graphical abstract, keywords, a declaration of competing interest, a Statement of Significance as a table at the end of the introduction using the headings Problem or Issue, What is Already Known, What this Paper Adds, and Who would benefit from the new knowledge in this paper in 150 words or fewer, and an AI declaration statement before the references if AI tools were used for manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance and include author names, journal or book titles, chapter or article titles, year, and volume numbers, article numbers, or pagination where applicable, with journal names abbreviated according to the List of Title Word Abbreviations.
Figures & Tables The total number of figures and tables must not exceed 8. Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures and other artwork must be supplied as separate files. The Statement of Significance must be presented as a table at the end of the introduction, all tables and figures must be cited in the text and numbered consecutively, tables must include captions, and figures must have captions with a brief title and description.
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Special Communication

Cover Letter A cover letter is required. The cover letter must specify that the manuscript is intended as a Special Communication.
Abstract A structured abstract is required. The abstract must be 300 words or fewer. The abstract must be structured. The abstract must use the headings Objective, Methods, Results, and Conclusion.
Manuscript The manuscript body must be 6000 words or fewer. The manuscript must be structured as Introduction, Related Work, Methods, Results, Discussion, and Conclusion. The manuscript must include a graphical abstract, keywords, a declaration of competing interest, a Statement of Significance table at the end of the introduction using the headings Problem or Issue, What is Already Known, What this Paper Adds, and Who would benefit from the new knowledge in this paper in 150 words or less, and an AI declaration statement at the end of the manuscript immediately before the references.
References References must be cited in the text using numbers in square brackets and listed in the order of appearance, with journal names abbreviated according to the List of Title Word Abbreviations.
Figures & Tables The total number of figures and tables must not exceed 8. Tables must be placed next to the relevant text or on separate pages at the end of the article, and figures must be supplied as separate files. Tables must be submitted as editable text rather than images and all figures and tables must be cited in the text and include captions.
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Letters To The Editor

Cover Letter A cover letter must be included with the submission.
Abstract Abstract must be 300 words or fewer. Abstract must be structured. Abstract must use the headings Objective, Methods, Results, and Conclusion.
Manuscript Manuscript body must be 6000 words or fewer. Manuscript must be organized as Introduction, Related Work, Methods, Results, Discussion, and Conclusion. The manuscript must include a graphical abstract, keywords, a Statement of Significance table at the end of the introduction with the headings Problem or Issue, What is Already Known, What this Paper Adds, and Who would benefit from the new knowledge in this paper in 150 words or fewer, a declaration of competing interest, and an AI declaration statement before the references if generative AI or AI-assisted technologies were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order they appear in the article and include author names, source title, article or chapter title where applicable, year, and volume, article number, or page range where applicable.
Figures & Tables The combined total number of figures and tables must not exceed 8. Tables must be placed next to the relevant text or on separate page or pages at the end of the article, and figures must be supplied as separate files. Tables must be submitted as editable text rather than images, and any generative AI-created images must be disclosed in each image caption.
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Recent Publications

GIN-CRC-Pareto: A graph-based pareto-optimized multi-task learning framework to identify miRNA-target interactions in colorectal cancer

Lin Li, Qiang Yang, Lu Li, Hongru Zhao, Jie Xu, Mingyi Xie, Rui Yin

10.1016/j.jbi.2026.105099
View Publication

Similarity-Adaptive interaction routing for Drug–Target affinity prediction

Ziyou Zhou, Min Chen, Wenjian Zhou, Qiong Xiao

10.1016/j.jbi.2026.105100
View Publication

TriFuse: A multi-signal three-stage data distillation framework for efficient medical model training

Ruilong Xu, Huan Fang

10.1016/j.jbi.2026.105094
View Publication

Evaluating teacher-supervised small medical language models for institution-constrained clinical QA

Gaoyuan Du, Dimitrios Dimitriadis, Xueping Li

10.1016/j.jbi.2026.105095
View Publication

PAC-Net: A physics-guided multimodal hybrid network for antibody-antigen interaction prediction

SongJian Wei, ChunYan Tang, Chen Yan, JinXiong Zhang, JiaYang Tan, Lilan Lv

10.1016/j.jbi.2026.105097
View Publication

Frequently asked questions

How long does it take to publish?

2 days from submission to first decision; 49 days from submission to decision after review; 142 days from submission to acceptance; 8 days from acceptance to online publication.

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Is a cover letter required?

A cover letter is required as part of the submission. For Special Communication and Commentary submissions, the cover letter should specify the manuscript type, and for Special Issue submissions it should indicate whether the article is an original research paper, methodological review, special communication, or commentary.

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What are the publication costs?

USD 3530 APC for open access articles; no open access publication fee for subscription publication

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Research Topics

Biomedical Text Mining and Ontologies Machine Learning in Healthcare Topic Modeling Electronic Health Records Systems Diverse Scientific and Economic Studies Semantic Web and Ontologies Bioinformatics and Genomic Networks Natural Language Processing Techniques Gene expression and cancer classification Legal and Regulatory Analysis Linguistic, Cultural, and Literary Studies Military Technology and Strategies Ferroelectric and Negative Capacitance Devices Artificial Intelligence in Healthcare Computational Drug Discovery Methods Human auditory perception and evaluation Educational Robotics and Engineering Data Quality and Management Artificial Intelligence in Healthcare and Education Mobile Health and mHealth Applications Scientific Computing and Data Management Spine and Intervertebral Disc Pathology Machine Learning in Bioinformatics Advanced Text Analysis Techniques AI in cancer detection

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