JO

Journal of Experimental & Clinical Cancer Research

Journal of Experimental & Clinical Cancer Research publishes multidisciplinary research on basic, clinical and translational oncology studies. It is ranked in the first quartile of the oncology category in Journal Citation Reports and operates on an open access platform.

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Subject Oncology
Impact Factor 12.8
Quartile Q1
Open Access Type Open
eISSN 1756-9966
Invitation Only No
Cost Range £3190.00 GBP / $4490.00 USD / €3790.00 EUR APC; subject to VAT or local taxes where applicable.

Submission Instructions

Journal of Experimental & Clinical Cancer Research accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter A cover letter is required. Cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the manuscript for submission, confirm the manuscript has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Methods, Results, and Conclusions, and for reports of health care interventions on human participants it must also include a Trial registration section with registration number and date, using the words 'retrospectively registered' if applicable.
Manuscript Manuscript must include Background, Methods, Results, Discussion, Conclusions, and a Declarations section, and the title page must include the title, full author names and institutional addresses, and the corresponding author. Manuscript must include three to ten keywords, a list of abbreviations if abbreviations are used, the required Declarations subsections with 'Not applicable' where a section is irrelevant, and any use of a Large Language Model must be documented in the Methods section or another suitable section if no Methods section is available.
References References must follow Vancouver style. Only published, in-press, or publicly available preprint articles, clinical trial registration records, and abstracts may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web references must include the site title, full URL, and access date.
Figures & Tables Tables shorter than one page may be placed in the manuscript at the appropriate location, longer tables may be placed at the end of the document with callouts in the text, and figure titles and legends must appear in the main manuscript while figure files are uploaded separately in citation order. Figures must be numbered in the order first mentioned and multi-panel figures submitted as a single composite file, while tables must be numbered and cited in sequence and created using the word processor's table function rather than embedded as figures or spreadsheet files.
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Review

Cover Letter A cover letter is required. The cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the submission, confirm that the manuscript has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include Background, Main body, and short Conclusion.
Manuscript The manuscript must include a title page, Background, Main text, Conclusions, and a Declarations section. The manuscript must include three to ten keywords, provide a list of abbreviations if abbreviations are used, and document any use of a Large Language Model in the Methods section or another suitable section if no Methods section is available.
References References must use Vancouver style. Web links and URLs must be assigned a reference number and included in the reference list in full with the site title, full URL, and access date.
Figures & Tables Tables shorter than one page may be placed within the manuscript, tables longer than one page may be placed at the end of the document, and figure titles and legends must be included in the main manuscript rather than in the graphic file. Figures and tables must be numbered in the order first cited in the text, multi-panel figures must be submitted as a single composite file, and tables must be created with the word processor's table function rather than embedded as figures.
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Commentary

Cover Letter A cover letter is required. Cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the submission, confirm that the manuscript has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. Abstract should not exceed 350 words. Abstract must be structured. Abstract must include Background, Main body, and short Conclusion.
Manuscript Commentary manuscripts should be a maximum of 1,500 words. Commentary manuscripts must include a title page, Background, Main text, Conclusions, and a Declarations section with all required subheadings. Commentary manuscripts must include three to ten keywords, a list of abbreviations if abbreviations are used, and all Declarations subheadings even if some are marked 'Not applicable'.
References Commentaries should have no more than 15 references. References must follow Vancouver style. Only published or in-press articles, trial registration records, abstracts, and public preprints may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and web links must be assigned a reference number and included in the reference list in full with access date.
Figures & Tables Commentaries should have no more than 2 figures and tables in total. Tables shorter than one page may be embedded in the manuscript, tables longer than one page may be placed at the end of the document, and figure titles and legends must be provided in the main manuscript while figures are uploaded separately. Figures and tables must be numbered in the order first cited, multi-panel figures must be submitted as a single composite file, and tables must be created using the word processor's Table object rather than embedded as figures or spreadsheet files.
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Meeting Report

Cover Letter A cover letter is required. The cover letter must explain any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the manuscript has not been published or submitted elsewhere, and name the special issue if applicable.
Abstract An abstract is required. The abstract must not exceed 250 words. The abstract is unstructured. The abstract must briefly summarize the aim, findings, or purpose of the article.
Manuscript The manuscript must include a title page, an abstract, three to ten keywords, the main text, and a Declarations section with the required subheadings, and the main text may be divided into short informative subsections. The manuscript must include three to ten keywords, define abbreviations at first use with a list of abbreviations if any are used, and include a Declarations section with the headings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information, using 'Not applicable' where a subsection is not relevant.
References References must follow Vancouver style. Only published articles, clinical trial registration records, and published or publicly available abstracts may be cited in the reference list, unpublished abstracts, unpublished data, and personal communications must be excluded, journal abbreviations must follow Index Medicus/MEDLINE, and web references must include the site title, full URL, and access date.
Figures & Tables Figure titles and legends must appear in the main manuscript rather than the image file, tables shorter than one page may be placed in the manuscript and longer tables may be placed at the end of the document with their intended placement indicated in the text. Figures and tables must be numbered in the order first cited in the text, multi-panel figures must be submitted as a single composite file, and tables must be created using the word processor's table function rather than embedded as figures or spreadsheet files.
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Recent Publications

Ferroptosis-based therapeutic strategy targeting iron metabolism and SLC7A11 overcomes oxaliplatin resistance in patient-derived pancreatic cancer organoids

Jin Ho Choi, Kyung Min Lee, Minsik Oh, Janghyun Noh, Yooyeon Kim, Eunhye Hwang, In Rae Cho, Woo Hyun Paik, Ji Kon Ryu, Ja-lok Ku, Sang Hyub Lee

10.1186/s13046-026-03745-z
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DCLK1 regulates stemness and IL-6/STAT3–dependent metastatic niche formation in chemoresistant ovarian cancer

Samrita Dogra, Sugantha Priya Elayapillai, Cole Hladik, Ameera Hasan, Maitreyee Das, Laura F. Mortan, Dongfeng Qu, Courtney W. Houchen, Bethany N. Hannafon

10.1186/s13046-026-03739-x
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Correction: The KLF16/MYC feedback loop is a therapeutic target in bladder cancer

Lisi Zheng, Jingxuan Wang, Shan Han, Li Zhong, Zefu Liu, Bin Li, Ruhua Zhang, Liwen Zhou, Xianchong Zheng, Zhenhua Liu, Cuiling Zeng, Ruonan Li, Yezi Zou, Liqin Wang, Yuanzhong Wu, Tiebang Kang

10.1186/s13046-026-03744-0
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Vaccine-expanded plasmablast-like B cells are associated with response to dendritic cell therapy in metastatic melanoma

Marcella Tazzari, Silvia Carloni, Jenny Bulgarelli, Sara Pignatta, Martine Bocchini, Claudia Piccinini, Davide Angeli, Michela Tebaldi, Irene Azzali, Maria Maddalena Tumedei, Filippo Piccinini, Francesca Tauceri, Francesco Limarzi, Fabio Nicolini, Maria Teresa Bochicchio, Milena Urbini, Giovanni Foschi, Nicola Romanini, Francesco de Rosa, Anna Maria Granato, Elena Pancisi, Massimiliano Petrini, Laura Ridolfi

10.1186/s13046-026-03731-5
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Extracellular vesicles from chemotherapy-induced senescent tumor cells reprogram hepatic phospholipid metabolism to promote pancreatic cancer liver metastasis

Bai’an Tao, Yecheng Xu, Wenteng Miao, Zhenmei Chen, Jichun Gu, Yujie Guo, Linjie Chen, Yang Di, Hang He, Chen Jin, Ji Li, Deliang Fu

10.1186/s13046-026-03741-3
View Publication

Frequently asked questions

How long does it take to publish?

First decision after submission within 30 days. Submission to first decision (median): 3 days.

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Is a cover letter required?

A cover letter is required. It should explain why the manuscript should be published in the journal, address any issues relating to journal policies, declare any potential competing interests, confirm that all authors approved the submission, confirm that the content has not been published or submitted elsewhere, and name the special issue if applicable. Authors may also suggest preferred or non-preferred peer reviewers in the cover letter.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £3190.00 GBP / $4490.00 USD / €3790.00 EUR, subject to VAT or local taxes where applicable.

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Research Topics

Cancer-related molecular mechanisms research MicroRNA in disease regulation Cancer Cells and Metastasis Circular RNAs in diseases Cancer, Hypoxia, and Metabolism Ferroptosis and cancer prognosis Immune cells in cancer Cancer Immunotherapy and Biomarkers RNA modifications and cancer Epigenetics and DNA Methylation Autophagy in Disease and Therapy Wnt/β-catenin signaling in development and cancer Extracellular vesicles in disease Hippo pathway signaling and YAP/TAZ Cancer-related Molecular Pathways Immunotherapy and Immune Responses Cancer Research and Treatments Cell death mechanisms and regulation Cancer Mechanisms and Therapy RNA Research and Splicing Cancer, Lipids, and Metabolism Angiogenesis and VEGF in Cancer Ubiquitin and proteasome pathways Glioma Diagnosis and Treatment Cancer-related gene regulation

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