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Molecular Metabolism

Molecular Metabolism is an open access journal included in PubMed and PMC. It publishes hypothesis-driven interdisciplinary research on energy homeostasis and the etiology, development, treatment, and health consequences of metabolic disorders such as obesity, diabetes, cardiovascular disease, and cancer, with a focus on mechanistic understanding and transformative impact across approaches ranging from molecules to man throughout the lifespan.

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Impact Factor 6.6
Quartile Q1
Open Access Type Open
ISSN 2212-8778
eISSN 2212-8778
Invitation Only No
Cost Range Article Publishing Charge (APC): USD 4,560 (excluding taxes)

Submission Instructions

Molecular Metabolism accepts the following article types. Click on an article type to view submission instructions.

Full-Length Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words. Abstract may be structured using appropriate headings. Abstract must state the purpose of the research, outline basic procedures, include the main findings and principal conclusions, and emphasize new and important aspects of the study or observations.
Manuscript Main text should be around 8500 words. Article must be divided into clearly defined and numbered sections. Manuscript must include 1 to 7 English keywords, article highlights of 3 to 5 bullet points, a declaration of competing interests document, and an AI-use declaration section before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance and journal names must be abbreviated according to LTWA.
Figures & Tables There must be no more than 8 figures and/or tables in total. Figures must be uploaded as separate files, while tables must be submitted as editable text. Tables must include captions and be cited and numbered consecutively in the text, and figures must have captions and be cited and numbered according to their sequence in the article.
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Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words. Abstract may be structured using appropriate headings. Structured abstract should state the purpose of the research, basic procedures, main findings, and principal conclusions, emphasizing new and important aspects of the study or observations.
Manuscript Main text should be around 7500 words. Article must be divided into clearly defined and numbered sections. Manuscript must include 1 to 7 keywords in English, provide article highlights as 3 to 5 bullet points, complete the declarations tool with the resulting document uploaded, and include an AI-use declaration section before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance and journal names must be abbreviated according to LTWA.
Figures & Tables Review Articles must have no more than 5 figures. Figures must be uploaded as separate files, while tables are submitted as editable text. Tables must include captions and be cited consecutively in the text, and figures must each have a caption and be numbered in sequence.
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Brief Communication

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words. Structured abstracts should use appropriate headings.
Manuscript Main text should be around 3500 words. Article must be divided into clearly defined and numbered sections. Manuscript must include 1 to 7 keywords in English, provide article highlights as a separate editable file with 3 to 5 bullet points of no more than 85 characters each, and include an AI declaration section before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order they appear in the article, and journal names must be abbreviated according to LTWA.
Figures & Tables Brief Communications must have no more than 4 figures. Figures must be supplied as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively, and accompanied by captions.
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Recent Publications

Transition to dietary plant-based proteins requires functional liver GDH for proper control of ammonia and energy homeostasis.

Yan Zhou, Angela M. Ramos-Lobo, Tingting Fu, Hector Gallart-Ayala, Julijana Ivanisevic, Pierre Maechler

10.1016/j.molmet.2026.102435
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TRIM47, stabilized by YTHDF3-mediated m6A modification, promotes cardiac lipid accumulation and aggravates diabetic cardiomyopathy

WEIYAN WANG, LINGLI XIE, GUILAN CHEN, XIN ZUO, MEILING ZHONG, TONG YANG, WEIHUA WU

10.1016/j.molmet.2026.102437
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Beyond Weight Loss: Disentangling the Direct Effects of Semaglutide vs Equivalent Calorie Restriction on Reproductive Systems of Male and Female Rats

Morgan R. Sotzen, Suyeun Byun, Ngozi O. Ibadin, Mya A. Knappenberger, Madison T. Bento, Mohammed Asker, Sergei Koshkin, Francisco J. Diaz, Karolina P. Skibicka

10.1016/j.molmet.2026.102436
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Mitochondrial NCLX Couples Glucagon- and PDE2A-Dependent Signals to Regulate Hepatic Lipid Metabolism

Essam A. Assali, Mahmoud Taha, Ahmad Salhab, Johnny Amer, Karthickeyan Chella Krishnan, Marko Kostic, Michaela Veliova, Alexandra J. Brownstein, Orian S. Shirihai, Rifaat Safadi, Israel Sekler

10.1016/j.molmet.2026.102433
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Human Brown Fat Metabolism Associates with Systemic Branched-Chain Amino Acids Homeostasis

Mueez U-Din, Francisco M. Acosta, Teemu Saari, Vanessa D. de Mello Laaksonen, Birgitta W. van der Kolk, Milena Monfort-Pires, Mercedes Clemente-Postigo, Tarja Niemi, Markku Taittonen, Marjo Tuomainen, Tobias Fromme, Marko Lehtonen, Karsten Kristiansen, John W. Newman, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Eija Pirinen, Martin Klingenspor, Kati Hanhineva, Juho Raiko, Kirsi A. Virtanen

10.1016/j.molmet.2026.102434
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Frequently asked questions

How long does it take to publish?

2 days submission to first decision; 24 days submission to decision after review; 70 days submission to acceptance; 6 days from acceptance to first online publication.

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What are the publication costs?

Article Publishing Charge (APC): USD 4,560 (excluding taxes).

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Research Topics

Adipose Tissue and Metabolism Pancreatic function and diabetes Regulation of Appetite and Obesity Adipokines, Inflammation, and Metabolic Diseases Metabolism, Diabetes, and Cancer Diet and metabolism studies Liver Disease Diagnosis and Treatment Diabetes Treatment and Management Biochemical Analysis and Sensing Techniques Diabetes and associated disorders Diet, Metabolism, and Disease Mitochondrial Function and Pathology Diverse Scientific and Economic Studies Academic Publishing and Open Access Mathematics, Computing, and Information Processing Cancer, Hypoxia, and Metabolism Endoplasmic Reticulum Stress and Disease Lipid metabolism and biosynthesis Epigenetics and DNA Methylation Peroxisome Proliferator-Activated Receptors Dietary Effects on Health Circadian rhythm and melatonin Fibroblast Growth Factor Research Receptor Mechanisms and Signaling Birth, Development, and Health