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NAR Cancer

NAR Cancer is a fully open access journal publishing original research and review articles at the intersection of the nucleic acids and cancer fields. The journal emphasizes rapid publication, a transparent and fair editorial process, and Open Science.

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Subject Oncology
Impact Factor 3.2
Quartile Q2
Open Access Type Hybrid
ISSN 2632-8674
eISSN 2632-8674
Invitation Only No
Cost Range Open access charge example shown: 3625 USD for a book review charge; corresponding authors in Low and Middle Income countries and regions may receive a waiver or discount of the APC.

Submission Instructions

NAR Cancer accepts the following article types. Click on an article type to view submission instructions.

Standard Articles

Cover Letter A cover letter is required for submission, and resubmissions must also be accompanied by a cover letter. The cover letter must briefly list the main conclusions, explain the significance of the work, include details and manuscript numbers of any previous related submissions to the journal or Nucleic Acids Research, disclose any AI use, and include any relevant personal communication or related-manuscript information.
Abstract A text abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured as a single paragraph without subheadings.
Manuscript The manuscript must follow the journal’s required article structure. The manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the contents and significance of the paper at submission, disclosure of any AI use in the Methods or Acknowledgements section, and the statement ‘Supplementary Data are available at NAR Online’ if supplementary material is included for publication.
References References must follow the Nucleic Acids Research style. References must be cited in the text by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations, give full article titles, and list only the first three authors followed by et al. when there are four or more authors.
Figures & Tables For initial submission, figures and tables should be embedded in the manuscript text, either inline or in a separate section at the end. Tables and figures must be numbered consecutively with captions or legends, tables must be editable rather than images if submitted separately, multipanel figures must be submitted as one composite image, and alt text must be provided for all images in the main manuscript file directly under the relevant figure legend.
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Review Articles

Cover Letter A cover letter is required, and resubmissions must be accompanied by one. Cover letter must briefly list the manuscript’s main conclusions, explain its significance, include details and manuscript numbers of any previous submission of the work, disclose any use of AI, and provide any cited personal communications with confirmation of permission.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured and written as a single paragraph. Abstract must not include subheadings.
Manuscript Manuscript structure is not explicitly specified for Review Articles beyond following the journal’s required article structure. Manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance at submission, a graphical abstract, and disclosure of any AI use in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance and listed numerically, with journal names abbreviated in Chemical Abstracts style, full article titles included, and for four or more authors only the first three listed followed by et al.
Figures & Tables For initial submission, all figures and tables should be embedded in the text within a single PDF file, while high-resolution individual figure files must be uploaded separately at revision. Tables must be editable and numbered with captions, and figures must be numbered with detailed captions and submitted as composite images for multipanel figures.
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Critical Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 200 words. Abstract must be unstructured and presented as a single paragraph without subheadings.
Manuscript Manuscript must include an Author Contributions statement and disclose any use of AI in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance and listed numerically, with journal names abbreviated in Chemical Abstracts style and only the first three authors listed before et al. when there are four or more authors.
Figures & Tables Figures and tables should be embedded in the text at initial submission. All figures and tables must have captions or legends, be numbered consecutively, and include alt text for all images in the main manuscript file directly under the relevant figure legend.
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Short Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 200 words. Abstract must be unstructured and presented as a single paragraph. Abstract must not include subheadings.
Manuscript Short Reviews generally occupy 4 printed pages or less. Manuscript must include an Author Contributions statement and disclose any use of AI in the Methods or Acknowledgements section.
References Short Reviews must include no more than 50 references. References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations, and list the first three authors followed by et al. when there are four or more authors.
Figures & Tables Short Reviews generally include 1–2 display items. Figures and tables should be embedded in the text at initial submission. Alt text must be provided for all figures and tables must have captions embedded in the text.
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Cancer Data Resource Articles

Cover Letter A cover letter is required. Cover letter must briefly list the manuscript’s main conclusions, explain its significance, include details and manuscript numbers of any previous submission of the work to the journal or to Nucleic Acids Research, disclose any AI use, and note any cited personal communications with confirmation of permission.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured as a single paragraph without subheadings. Abstract must include the resource URL if applicable.
Manuscript Manuscript must include a brief description of the resource and focus on factual content and methods by which the information can be accessed and retrieved. Manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance at submission, a graphical abstract, and disclosure of any AI use in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations, and list only the first three authors followed by et al. when there are four or more authors.
Figures & Tables Figures and tables should be embedded in the manuscript text at initial submission. All figures and tables must have captions or legends and alt text must be provided for all figures in the main manuscript file directly below the relevant figure legend.
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Critical Reviews And Perspectives

Cover Letter A cover letter is required. Cover letter must briefly list the main conclusions, explain the significance of the work, disclose any AI use, and include details and manuscript numbers for any previous submission of the work.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured and presented as a single paragraph. Abstract must not include subheadings.
Manuscript Critical Reviews and Perspectives typically occupy about 15 printed pages. Manuscript must include an Author Contributions statement and disclose any AI use in the Methods or Acknowledgements section.
References Critical Reviews and Perspectives typically include 100–150 references. References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations, and list only the first three authors followed by et al. when there are four or more authors.
Figures & Tables Critical Reviews and Perspectives typically include 4–6 display items. Figures and tables should be embedded in the text at initial submission. All figures and tables must include captions or legends and be cited in the text.
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Cancer Computational Biology

Cover Letter A cover letter is required and must briefly list the manuscript’s main conclusions, explain its significance, include details and manuscript numbers of any previous submission of the work to this journal or Nucleic Acids Research, and disclose any use of AI. The cover letter must briefly list the main conclusions, explain the significance of the work, provide details and manuscript numbers of any previous submission of the work to this journal or Nucleic Acids Research, and disclose any use of AI.
Abstract A text abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured as a single paragraph without subheadings.
Manuscript The manuscript must follow the journal’s required article structure, and articles should include a Data Availability Statement following the Discussion. The manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance, a mandatory graphical abstract, and disclosure of any AI use in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations, give full article titles, and list only the first three authors followed by et al. when there are four or more authors.
Figures & Tables For initial submission, figures and tables should be embedded in the manuscript text, and supplementary data must be uploaded as separate files. Tables and figures must be numbered consecutively with captions or legends, tables must be editable rather than image files, multipanel figures must be submitted as one composite image, and alt text must be provided under each figure legend.
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Cancer Genomics

Cover Letter A cover letter is required. Cover letter must briefly list the manuscript’s main conclusions, explain its significance, include details and manuscript numbers of any previous submission of the work to this journal or Nucleic Acids Research, disclose any AI use, and provide details of any personal communications and related manuscripts under consideration that could affect interpretation.
Abstract A text abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured in a single paragraph. Abstract must not include subheadings.
Manuscript Manuscript must follow the journal’s required article structure, and articles should include a Data Availability Statement following the Discussion. Manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance at submission, a graphical abstract, and AI use disclosures in the Methods or Acknowledgements section if applicable.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance and listed numerically, with journal names abbreviated in Chemical Abstracts style, full article titles provided, and for references with four or more authors only the first three listed followed by et al.
Figures & Tables At initial submission, all figures and tables should be embedded in the text, while supplementary data must be uploaded separately. Figures and tables must be numbered consecutively and include captions or legends, and figures must also have alt text provided directly under the relevant figure legend in the main manuscript file.
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Dna Damage, Sensing And Repair

Cover Letter A cover letter is required. The cover letter must briefly list the manuscript’s main conclusions, explain its significance, include details and manuscript numbers of any previous submission of the work to the journal or Nucleic Acids Research, disclose AI use, and note any personal communications or related manuscripts under consideration that could affect interpretation.
Abstract An abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured in a single paragraph.
Manuscript The manuscript should follow the journal’s required article structure. The manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance, a graphical abstract at initial submission, and disclosure of any AI use in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance and listed numerically, with journal names abbreviated in Chemical Abstracts style and only the first three authors given before et al. when there are four or more authors.
Figures & Tables At initial submission, figures and tables should be embedded in the manuscript text, and supplementary data must be uploaded separately. Tables and figures must be numbered consecutively with captions or legends, figure captions must be detailed, multipanel figures must be submitted as one composite image, and alt text must be provided under each figure legend in the manuscript.
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Cancer Gene Regulation, Chromatin And Epigenetics

Cover Letter A cover letter is required. Cover letter must briefly list the manuscript’s main conclusions, explain the work’s significance, include details and manuscript numbers of any previous submission of the work to the journal or to Nucleic Acids Research, include details of any cited personal communications with confirmation of permission, and disclose any use of AI to help generate content or images, write code, process data, or provide translation.
Abstract A text abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured and presented as a single paragraph. Abstract must not include subheadings.
Manuscript Manuscript should follow the journal’s required article structure. Manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the contents and significance of the paper, a graphical abstract, and disclosure of any AI use in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance and listed numerically, journal names must be abbreviated in Chemical Abstracts style, full article titles must be given, and references with four or more authors must list the first three followed by et al.
Figures & Tables At initial submission, all figures and tables should be embedded in the text, either in line with the Results section or in a separate section at the end. Figures and tables must be numbered consecutively with captions or legends embedded in the manuscript, and alt text must be provided for all images directly under the relevant figure legend.
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Cancer-Specific Rnas And Rna Processing

Cover Letter A cover letter is required. The cover letter must briefly list the manuscript’s main conclusions, explain its significance, disclose any previous submission of the work with manuscript numbers, include any personal communication details and permissions if applicable, disclose related manuscripts under consideration elsewhere, and disclose any use of AI.
Abstract An abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured as a single paragraph without subheadings.
Manuscript The manuscript must follow the journal’s required article structure, and articles should include a Data Availability Statement following the Discussion. The manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance at submission, a mandatory graphical abstract, AI disclosures in the Methods or Acknowledgements section if applicable, and the statement ‘Supplementary Data are available at NAR Online’ if supplementary material is included.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance and listed numerically, journal names must be abbreviated in Chemical Abstracts style, full article titles must be given, and references with four or more authors must list the first three followed by et al.
Figures & Tables For initial submission, figures and tables should be embedded in the manuscript text, while supplementary data must be uploaded separately. Tables and figures must be numbered consecutively with captions or legends, tables must be editable rather than image files if needed, multipanel figures must be submitted as one composite image, and alt text must be provided for all images directly under the relevant figure legend.
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Nucleic Acid-Based Cancer Therapeutics

Cover Letter A cover letter is required with submission, and resubmissions must also include one. The cover letter must briefly list the manuscript’s main conclusions and significance, include details and manuscript numbers of any previous submissions of the work, and disclose any use of AI to help generate content or images, write code, process data, or provide translation.
Abstract A text abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured and presented as a single paragraph. The abstract must not include subheadings.
Manuscript The manuscript must follow the journal’s required article structure. The manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the contents and significance, a graphical abstract, and disclosure of any AI use in the Methods or Acknowledgements section.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations, and list only the first three authors followed by et al. when there are four or more authors.
Figures & Tables At initial submission, figures and tables should be embedded in the manuscript text, while at revision individual high-resolution figure files must be uploaded separately. Tables must be editable and captioned, figures must include detailed captions and alt text in the manuscript, and multipanel figures must be submitted as one composite image.
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Cancer Data Resources

Cover Letter A cover letter is required. Cover letter must briefly list the manuscript’s main conclusions, explain its significance, include details and manuscript numbers for any prior submission of the work to this journal or Nucleic Acids Research, note any cited personal communications with permission confirmation, disclose AI use, and explain how the submission differs from related manuscripts.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured as a single paragraph without subheadings. The resource URL, if applicable, must appear in the abstract.
Manuscript Manuscript must follow the journal’s required article structure, and the resource name should be featured in the article title. Manuscript must include an Author Contributions statement, approximately three one-sentence bullet points summarizing the paper’s contents and significance at submission, a graphical abstract, an AI-use disclosure in the Methods or Acknowledgements section if applicable, and the statement 'Supplementary Data are available at NAR Online' if supplementary material is included.
References References must follow the Nucleic Acids Research style. References must be cited by sequential number in order of appearance, listed numerically, use Chemical Abstracts journal abbreviations and full article titles, and list only the first three authors followed by et al. when there are four or more authors.
Figures & Tables Figures and tables should be embedded in the manuscript text at initial submission, and individual high-resolution figure files must be uploaded separately at revision. Tables must be editable and numbered consecutively with captions, while figures must be numbered consecutively with captions and alt text included directly under the relevant legend in the main manuscript file.
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Recent Publications

MYC and AP-1 oncogenes cooperatively bind enhancers to rewire transcription

Reshma Kalyan Sundaram, Kshitiz Parihar, Stephanie Monson, Ravi Radhakrishnan, Bomyi Lim

10.1093/narcan/zcag010
View Publication

Efficient gene disruption with CRISPR–Cas3 in human T cells

Tomoaki Fujii, Yukimi Sakoda, Kazuto Yoshimi, Kohei Takeshita, Shoji Watanabe, Ryuya Iida, Tsubasa Obo, Kazumasa Yokoyama, Koji Tamada, Tomoji Mashimo

10.1093/narcan/zcag009
View Publication

Uncovering novel germline variants associated with testicular germ cell tumors by exome sequencing

Berenice Cuevas-Estrada, Juan A Ríos-Rodríguez, José A García-Pacheco, Talia Wegman-Ostrosky, Alejandra Cervera, Nicolas Alcaraz, Michel Montalvo-Casimiro, Alejandra Barrón-Hernández, Clementina Castro-Hernández, Miguel A Jiménez-Ríos, Nora Sobrevilla-Moreno, Cristian Arriaga-Canon, Luis A Herrera, Rodrigo González-Barrios

10.1093/narcan/zcag007
View Publication

Sensitive detection of somatic mutations in GC-rich cancer gene promoters

Meifang Qi, Preshita Sanjay Dave, Nicole Francis, Matthew DeFelice, Sam Pollock, Holly Corbitt, Irene Rin Mitsiades, Gengchao Wang, Paul Frere, Alan Fox, Gregory Khitrov, Caroline Petersen, Katie Larkin, Susanna Hamilton, Leif W Ellisen, Doga C Gulhan, Alfredo Hidalgo-Miranda, Niall Lennon, Carrie Cibulskis, Esther Rheinbay

10.1093/narcan/zcag011
View Publication

Disruption of the structural maintenance of chromosomes 5/6 complex enables tumor mutagenesis

Thi Tran, Jiayi Fan, Xiaolan Zhao, Abby M Green

10.1093/narcan/zcag012
View Publication

Frequently asked questions

How long does it take to publish?

Papers are published in the currently open issue after copyediting and review of the final proof. Authors are encouraged to submit revisions within 30–60 days, extensions up to six months may be requested, and proofs should be corrected within 48 hours.

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Is a cover letter required?

A cover letter should be uploaded at submission. It should briefly list the main conclusions, explain the significance of the work, disclose previous submissions, related manuscripts under consideration elsewhere, and any personal communications or AI use as required. Cover letters are required for resubmissions and may be used to request exclusion of specific reviewers.

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What are the publication costs?

Articles in hybrid journals may be published open access upon payment of an Article Processing Charge (APC). An example open access charge shown is 3625 USD for a book review. Corresponding authors in Low and Middle Income countries and regions may receive a waiver or discount of the APC.

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Research Topics

DNA Repair Mechanisms RNA modifications and cancer Cancer Genomics and Diagnostics RNA Research and Splicing PARP inhibition in cancer therapy CRISPR and Genetic Engineering Epigenetics and DNA Methylation Cancer-related molecular mechanisms research Genomics and Chromatin Dynamics RNA and protein synthesis mechanisms Cancer-related gene regulation Genetic factors in colorectal cancer DNA and Nucleic Acid Chemistry Cancer-related Molecular Pathways Advanced biosensing and bioanalysis techniques RNA Interference and Gene Delivery Cancer therapeutics and mechanisms MicroRNA in disease regulation Prostate Cancer Treatment and Research Ubiquitin and proteasome pathways Single-cell and spatial transcriptomics Ferroptosis and cancer prognosis Circular RNAs in diseases Chromatin Remodeling and Cancer Protein Degradation and Inhibitors

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