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Nature Reviews Bioengineering

Nature Reviews Bioengineering publishes Reviews, Analysis, Comments, Editorials and related content across bioengineering, including topics such as digital twins, cell engineering, organoids, microrobots, drug delivery, biomarkers and neuromodulation.

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Subject Engineering, Biomedical, Materials Science, Biomaterials
Impact Factor 37.6
Quartile Q1
Open Access Type Closed
eISSN 2731-6092
Invitation Only Yes
Cost Range Subscription publication route; immediate gold open access is not offered.

Submission Instructions

Nature Reviews Bioengineering is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review

Cover Letter Cover Letter requirements are not specified.
Abstract A 200-word abstract is required for the proposal synopsis. The proposal synopsis abstract must be 200 words. The manuscript abstract must be unstructured.
Manuscript Review articles are approximately 6,000 words long. The article should open with an introductory section without subheadings and end with a brief summary section without subheadings. The manuscript must include 4–6 key point bullets of no more than 30 words each and a statement of responsibility specifying each author's contribution, and glossary terms are not allowed.
References Review articles may contain up to 150 references. References must use Nature Reviews style. References must be cited as superscript numbers in sequential order and list only the first author followed by 'et al.' when there are six or more authors.
Figures & Tables Review articles typically include 5–7 display items in total, including figures, tables, and boxes. Tables must be provided as part of the article document, except tables containing graphical content, which must be provided as separate image files. Display items must be cited in the main text in order, and figures, tables, and boxes must each have a short title.
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Perspective

Cover Letter Cover Letter requirements are not specified.
Abstract Perspective articles must include an unstructured abstract. Abstract should ideally be a maximum of 200 words. Abstract must be unstructured.
Manuscript Perspective articles are approximately 5,000 words long. Manuscript must include an introductory section without subheadings, may use up to three levels of headings, and must end with a brief concluding section without subheadings. Manuscript must include 4–6 brief key points of 30 words or fewer each, a competing interests statement, a statement of responsibility specifying every author's contribution, documentation of any LLM use in the Methods section or another suitable section, and no glossary terms.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. Citations must be superscript numbers cited sequentially with the reference list ordered by main text, tables, figures, and then boxes, and references with six or more authors must list only the first author followed by 'et al.'.
Figures & Tables Perspective articles may include no more than 5 display items, including tables, figures, and boxes. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title, no legend, entries in all cells, defined abbreviations, and at least three columns of data, while figures must be fully labelled and include a short title and brief concise legend defining abbreviations.
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Comment

Cover Letter Cover Letter requirements are not specified.
Abstract A 200-word abstract is required for the proposal synopsis. The proposal synopsis abstract must be 200 words. The abstract must be unstructured.
Manuscript Comment articles are approximately 1,200 words long. Comment articles must include a standfirst of no more than 50 words and may use only one level of heading. The manuscript must include competing interests within the text, a statement of responsibility specifying each author's contribution, and documentation of any LLM use in the Methods section or another suitable part of the manuscript if no Methods section is available.
References Comment articles contain 10 references. References must use Nature Reviews style. References must be cited as superscript numbers in sequential order of main text, tables, figures, and then boxes, and references with six or more authors must list only the first author followed by 'et al.'.
Figures & Tables Comment articles are limited to one simple and concise display item or one image. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Display items should ideally occupy no more than one-quarter of an A4 page and may occupy a maximum of half a page, tables must have a short title and no legend, and figures must be fully labelled with a short title and concise legend.
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Down To Business

Cover Letter Cover Letter requirements are not specified.
Abstract A 200-word abstract is required for the proposal synopsis. The proposal synopsis abstract must be 200 words. The abstract must be unstructured.
Manuscript The proposal must be submitted as a synopsis that includes a brief description of the main article sections. The manuscript must include a statement of responsibility specifying the contribution of every author, and glossary terms are not allowed.
References References must use Nature Reviews style. References must be cited as superscript numbers in sequential order, with six or more authors shortened to the first author followed by 'et al.', and the numbered reference list placed at the end of the article.
Figures & Tables Display items are limited to 7 total, including tables, figures, and boxes. Tables must be provided as part of the article document. Display items must be cited in the main text in order, and tables, figures, and boxes must each have a short title.
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Recent Publications

Wild bat targeted vaccines

Tonie E. Rocke

10.1038/s44222-026-00450-6
View Publication

Bioengineering the path to clinical xenotransplantation

-

10.1038/s44222-026-00443-5
View Publication

Thinking is not only writing

Brian D. Earp, Anne-Sophie Guernon, Sebastian Porsdam Mann

10.1038/s44222-026-00447-1
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Endocrine effects in cell culture

Alison Marieann Veintimilla, Erika Moore

10.1038/s44222-026-00452-4
View Publication

Organoids as platforms for infectious disease research

Kuan Liu, Yilan Zhao, Erika M. Joloya, Benedetta Artegiani, Sina Bartfeld, Young Ki Choi, Yuling Han, Delilah Hendriks, Martin J. Hoogduijn, James E. Hudson, Luc J. W. van der Laan, Cun Li, Valeria V. Orlova, Jianhua Qin, Karine Raymond, Lisa E. Wagar, Jie Zhou, Mart M. Lamers, Qiuwei Pan

10.1038/s44222-026-00445-3
View Publication

Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 3 days. Median time from submission to acceptance is 203 days.

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Is a cover letter required?

Nature Portfolio journals do not require all authors of a research paper to sign the letter of submission. The corresponding author is responsible for manuscript submission and must provide written permission for mention of unpublished material and for re-use of previously published material at submission.

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What are the publication costs?

Subscription publication route; immediate gold open access is not offered.

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Research Topics

3D Printing in Biomedical Research Neuroscience and Neural Engineering Biomedical and Engineering Education Advanced Sensor and Energy Harvesting Materials CRISPR and Genetic Engineering RNA Interference and Gene Delivery Nanoplatforms for cancer theranostics Pluripotent Stem Cells Research Nanoparticle-Based Drug Delivery Advanced biosensing and bioanalysis techniques Cellular Mechanics and Interactions Micro and Nano Robotics CAR-T cell therapy research EEG and Brain-Computer Interfaces Additive Manufacturing and 3D Printing Technologies Biosensors and Analytical Detection Artificial Intelligence in Healthcare and Education Tissue Engineering and Regenerative Medicine Modular Robots and Swarm Intelligence Extracellular vesicles in disease Microbial Metabolic Engineering and Bioproduction Microfluidic and Bio-sensing Technologies Innovative Microfluidic and Catalytic Techniques Innovation Viral Infectious Diseases and Gene Expression in Insects Photoreceptor and optogenetics research

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