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Nature Reviews Clinical Oncology

Nature Reviews Clinical Oncology is a review journal covering clinical oncology and related advances in cancer diagnosis, management, therapeutics, epidemiology and precision medicine, publishing content such as Review Articles, Comments, Research Highlights and News & Views.

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Subject Oncology
Impact Factor 82.2
Quartile Q1
Open Access Type Hybrid
ISSN 1759-4774
eISSN 1759-4782
Invitation Only Yes
Cost Range No fee for publication.

Submission Instructions

Nature Reviews Clinical Oncology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review-Type

Cover Letter Cover Letter requirements are not specified.
Abstract A proposal synopsis must include an abstract. The abstract in the proposal synopsis must be 200 words.
Manuscript The proposal synopsis must include a brief description of the main article sections. The proposal synopsis must include a list of key references and the list of authors and their affiliations, and any use of an LLM must be documented in the Methods section or a suitable alternative section if no Methods section is available.
References References requirements are not specified.
Figures & Tables Figures & Tables requirements are not specified.
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Perspective

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required for Perspective manuscripts. The abstract should ideally be no more than 200 words. The abstract must be unstructured.
Manuscript The manuscript must include an introductory section without subheadings and end with a brief summary section without subheadings. The manuscript must include competing interests, document any LLM use in the Methods section or another suitable section if no Methods section exists, and key points are optional but if included must contain 4–6 bullet points of no more than 30 words each.
References References must use Nature Reviews style. References must be cited as sequential superscript numbers, listed in the order main text, tables, figures, and then boxes, and for works with six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables Perspective articles may include no more than 5 display items in total. Tables must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. All figures must have a brief legend and tables must have a short title.
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Consensus Statement

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured.
Manuscript Manuscript must begin with an introduction without subheadings, may use up to three levels of headings, include a brief Methods section describing methodology and relevant search strategy, decision-making process, inclusion and/or exclusion criteria, and stakeholder details, and end with a brief concluding summary section without subheadings. Use of an LLM must be documented in the Methods section or another suitable part of the manuscript, and competing interests must be declared within the text of the article.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as superscript numbers sequentially in the order of appearance in the main text, tables, figures, and then boxes, and works with six or more authors must list only the first author followed by 'et al.'.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Tables must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Display items must be cited in the main text in order as (FIG. 1), tables and boxes must have short titles, figures must be fully labelled with a short title and concise legend defining abbreviations, and all abbreviations in tables must be defined.
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Evidence-Based Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract An unstructured abstract is required. Abstract should ideally be no more than 200 words. Abstract must be unstructured. Abstract must not contain headings, references, or display item citations and must contain minimal specialist details with all abstracted information addressed in the main article.
Manuscript Manuscript must include an introduction without subheadings, a Methods section describing methodology and stakeholders, and a brief concluding summary section without subheadings, with up to three levels of headings allowed. Use of an LLM must be documented in the Methods section or, if no Methods section is available, in a suitable alternative part of the manuscript.
References References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers in the order of main text, tables, figures, and then boxes, and references with six or more authors must list only the first author followed by 'et al.'.
Figures & Tables No more than 7 display items, including tables, figures, and boxes, are allowed. Tables must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Display items must be cited in the main text in order as (FIG. 1), tables and boxes must have a short title, figures must be fully labelled with a short title and concise legend defining abbreviations, and all abbreviations in tables must be defined.
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Recent Publications

Liquid biopsy to inform adjuvant decisions during neoadjuvant chemotherapy — a full-circle moment for nasopharyngeal cancer

W. K. Jacky Lam, Brigette B. Y. Ma

10.1038/s41571-026-01157-8
View Publication

The transformative role of SBRT in the management of spinal metastases

K. Liang Zeng, Pejman Jabehdar Maralani, Michael Hardisty, Hanbo Chen, Jay Detsky, Deepak Dinakaran, Hany Soliman, Chia-Lin Tseng, Jeremie Larouche, Jetan Badhiwala, Elizabeth David, Katarzyna J. Jerzak, Amit Singnurkar, Chris Heyn, Cari Whyne, Mark Ruschin, Arjun Sahgal

10.1038/s41571-026-01152-z
View Publication

Synergistic integration of regional and systemic therapies in uveal melanoma

Shaheer A. Khan, Richard D. Carvajal

10.1038/s41571-026-01155-w
View Publication

The clinical landscape of HIF2α inhibitors in oncology

Eddy Saad, Marc Machaalani, David F. McDermott, Toni K. Choueiri

10.1038/s41571-026-01145-y
View Publication

Emerging trends in the global burden of colorectal cancer

David J. Lee, Aparna Parikh, Bhawna Sirohi, Yin Cao, Andrew T. Chan

10.1038/s41571-026-01149-8
View Publication

Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 4 days. Median time from submission to acceptance is 122 days.

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What are the publication costs?

Articles are published via the subscription route with no immediate gold open access option. No publication fee is charged.

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Research Topics

Cancer Genomics and Diagnostics Lung Cancer Treatments and Mutations Cancer Immunotherapy and Biomarkers CAR-T cell therapy research Colorectal Cancer Treatments and Studies Chronic Lymphocytic Leukemia Research Lymphoma Diagnosis and Treatment HER2/EGFR in Cancer Research Cancer Treatment and Pharmacology Pancreatic and Hepatic Oncology Research Lung Cancer Research Studies Hepatocellular Carcinoma Treatment and Prognosis Radiomics and Machine Learning in Medical Imaging Gastric Cancer Management and Outcomes Prostate Cancer Treatment and Research Immunotherapy and Immune Responses Multiple Myeloma Research and Treatments Glioma Diagnosis and Treatment Breast Cancer Treatment Studies Health Systems, Economic Evaluations, Quality of Life Genetic factors in colorectal cancer Immune Cell Function and Interaction Chronic Myeloid Leukemia Treatments Protein Degradation and Inhibitors Economic and Financial Impacts of Cancer