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Translational Lung Cancer Research

Translational Lung Cancer Research is an international, peer-reviewed, open-access journal indexed by Science Citation Index Expanded (SCIE) and PubMed/PubMed Central, focusing on cutting-edge development on the transition from preclinical to clinical research, including but not limited to multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention, and technical advances related to lung cancer and relevant thoracic diseases.

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Subject Oncology, Respiratory System
Impact Factor 3.5
Quartile Q2
Open Access Type Open
ISSN 2218-6751
eISSN 2226-4477
Invitation Only No

Submission Instructions

Translational Lung Cancer Research accepts the following article types. Click on an article type to view submission instructions.

Original Article

Cover Letter Any use of AI tools must be disclosed in the cover letter, including the prompts used, the time and date of queries, and the AI tool and version.
Abstract A structured abstract is required for Original Articles. Abstract must be 200–450 words. Abstract must be structured. Abstract must use the headings Background, Methods, Results, and Conclusions.
Manuscript Original Articles have no fixed word limit, but the main text word count excluding the abstract, references, tables, boxes, or figures must be provided at submission. Main text must be organized as Introduction, Methods, Results, Discussion, and Conclusions. Manuscript must include 3–5 keywords, a highlight box of no more than 250 words with the sections Key findings, What is known and what is new?, and What is the implication, and what should change now?, a Contributions section unless there is only one author using the specified contribution headings, and disclosure of any AI tool use in the Materials and Methods and Acknowledgment.
References References must follow Vancouver style. Citations must use numbers in round brackets in consecutive order of first appearance, journal titles must be abbreviated in Index Medicus style, and references with more than three authors must list the first three followed by “et al.”.
Figures & Tables Figures must be provided in separate files, and tables are recommended to be provided in separate files. Tables must be numbered consecutively and be editable rather than images, and figures must be cited in order and accompanied by figure legends including the figure title, abbreviation expansions, and symbol descriptions.
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Review Article

Cover Letter Cover letter must disclose any use of AI tools in manuscript writing, image or graphical production, or data collection and analysis. AI disclosure in the cover letter must include all prompts used, the full prompt used to generate results, the time and date of the query, and the AI tool and version.
Abstract Review Articles must include an abstract. Abstract must be 200–350 words. Abstract structure is not specified.
Manuscript Review Articles must not exceed 6,000 words including the abstract but excluding references, tables, and figures. Manuscript must include Introduction, main body, and Conclusions. Review Articles must include 3–5 keywords, the main body must discuss the main strengths and limitations, and a Contributions section should be included with the headings Conception and design; Administrative support; Provision of study materials or patients; Collection and assembly of data; Data analysis and interpretation; Manuscript writing: All authors; Final approval of manuscript: All authors.
References References must follow Vancouver style. References must be cited as numbers in round brackets in consecutive order of first appearance, journal titles must use Index Medicus abbreviations, and the reference list must list all authors for up to three authors or the first three followed by “et al.” for more than three.
Figures & Tables Figures must be provided in separate files, and tables are recommended to be provided in separate files. Tables must be editable and numbered consecutively, and figures must be cited in order and accompanied by figure legends including the figure title, abbreviation definitions, symbol explanations, and separate descriptions for each part of combination figures.
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Systematic Reviews Without Meta-Analysis

Cover Letter Any use of AI tools must be disclosed in the cover letter, including the prompts used, the time and date of queries, and the AI tool name and version.
Abstract A structured abstract is required. Abstract must be 200–350 words. Abstract must be structured. Abstract must use the headings Background, Methods, Results, and Conclusions.
Manuscript Manuscript must not exceed 6,000 words. Main text must be organized as Introduction, Methods, Results, Discussion, and Conclusions. Manuscript must include 3–5 keywords and a highlight box of no more than 250 words with the sections Key findings; What is known and what is new?; What is the implication, and what should change now?
References References must follow Vancouver style. Citations must use numbers in round brackets in consecutive order of first appearance, and the reference list must abbreviate journal titles in Index Medicus style and list up to three authors or the first three followed by “et al.”
Figures & Tables Tables are recommended in separate files and figures must be provided in separate files.
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Narrative Review (Also Called Literature Review)

Cover Letter Cover letter is required only to disclose any use of AI tools in manuscript writing, image or graphical production, or data collection and analysis. Any AI-use disclosure in the cover letter must report the prompts used, the full prompt used to generate results, the time and date of the query, and the AI tool and version.
Abstract Structured abstract is required. Abstract must be 200–350 words. Abstract must be structured. Abstract headings must be Background and Objective, Methods, Key Content and Findings, and Conclusions.
Manuscript Manuscript must not exceed 6,000 words. Main text must be organized as Introduction, Methods, main body, and Conclusions. Manuscript must include 3–5 keywords, a completed search strategy summary table in the Methods section covering search date, sources, terms, timeframe, inclusion and exclusion criteria, and selection process, and the statement “We present this article in accordance with the narrative review reporting checklist” at the end of the Introduction.
References References must follow Vancouver style. Citations must use numbers in round brackets in consecutive order of first appearance, and the reference list must abbreviate journal titles per Index Medicus and list all authors for up to three authors or the first three followed by “et al.” for more than three authors.
Figures & Tables Tables and figures must be provided in separate files. The Methods section must include a completed search strategy summary table reporting the search date, databases and other sources, search terms, timeframe, inclusion and exclusion criteria, and selection process.
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Scoping Review

Cover Letter Cover letter is required only if it is used to disclose any AI tool use in manuscript writing, image or graphical production, or data collection and analysis. Cover letter must disclose any AI tool use and include all prompts used, the full prompt used to generate research results, the time and date of each query, and the AI tool name and version.
Abstract Structured abstract is required. Abstract must be 200–350 words. Abstract must be structured. Abstract must use the headings Background, Methods, Results, and Conclusions.
Manuscript Manuscript must not exceed 6,000 words. Main text must be organized as Introduction, Methods, Results, Discussion, and Conclusions. Manuscript must include 3–5 keywords, a highlight box of no more than 250 words with the sections Key findings; What is known and what is new?; What is the implication, and what should change now?, and the statement “We present this article in accordance with the PRISMA-ScR reporting checklist” at the end of the Introduction.
References References must follow Vancouver style. Citations must be numbered in round brackets in order of first appearance, journal titles must use Index Medicus abbreviations, and reference lists must name up to three authors or the first three followed by “et al.” for more than three authors.
Figures & Tables Tables are recommended to be provided in separate files and figures must be provided in separate files. Tables must be numbered consecutively and be editable rather than images, and figures must be cited in order and accompanied by figure legends that include the figure title, abbreviations, symbols, and descriptions of each part for combination figures.
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Clinical Practice Review

Cover Letter Cover letter is required for AI-use disclosure and for attaching permission letters for reproduced figures. Cover letter must disclose any use of AI tools and include the tool and version, all prompts used, and the time and date of each query.
Abstract Abstract is required and must be unstructured. Abstract must be 200–350 words. Abstract must be unstructured. No mandatory abstract headings are specified.
Manuscript Manuscript must not exceed 6,000 words. Manuscript must include Introduction, main body, and Conclusions. Manuscript must include 3–5 keywords, and any use of AI tools must be disclosed in the Materials and Methods and Acknowledgment sections.
References References must follow Vancouver style. References must be numbered consecutively in order of first citation using numbers in round brackets, journal titles must follow Index Medicus abbreviations, and lists with more than three authors must show the first three followed by et al.
Figures & Tables Tables are recommended in separate files and figures must be provided in separate files. Tables must be editable and numbered consecutively, and figures must be cited in order and accompanied by figure legends.
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Mini-Review

Cover Letter Cover letter is required to disclose any use of AI tools in manuscript writing, image or graphical production, or data collection and analysis. Cover letter must disclose any AI tool use and include all prompts used, the full prompt used to generate results, the time and date of each query, and the AI tool name and version.
Abstract Abstract is required. Abstract must be 200–350 words. Abstract must be unstructured. No mandatory abstract headings are specified.
Manuscript Manuscript must not exceed 3,000 words excluding abstract, references, tables, and figures. Main text must be unstructured, and a separate Discussion section is not required. Manuscript must include 3–5 keywords and disclose any AI tool use in the manuscript.
References References must not exceed 30. References must follow Vancouver style. References must be cited with numbers in round brackets in consecutive order, list all authors when there are up to three, list the first three authors followed by “et al.” when there are more than three, and use Index Medicus journal abbreviations.
Figures & Tables Figures and tables must not exceed 3 in total. Tables and figures must be provided in separate files. Tables must be editable and not submitted as images, and figure legends are required for all figures.
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Clinical Practice Guideline

Cover Letter AI tool use must be disclosed in the cover letter. The cover letter must disclose any use of AI tools and include all prompts used, the time and date of each query, and the AI tool name and version.
Abstract A structured abstract is required. The abstract must be 200–350 words. The abstract must be structured. The abstract must use the headings Background, Methods, Results, and Conclusions.
Manuscript There is no fixed word limit, but the main text word count excluding the abstract, references, tables, boxes, or figures must be provided at submission. The main text must be organized as Introduction, Methods, main body containing clear recommendations and discussions, and Conclusions. The manuscript must include 3–5 keywords, a highlight box of no more than 300 words using the sections Key recommendations, What was recommended and what is new?, and What is the implication, and what should change now?, and a Contributions section with the specified author-contribution headings.
References References must follow Vancouver style. Citations must use numbers in round brackets in consecutive order of first appearance, and the reference list must abbreviate journal titles per Index Medicus and list up to three authors in full or the first three followed by “et al.” for more than three authors.
Figures & Tables Tables are recommended to be provided in separate files, and figures must be provided in separate files. Figure legends are required for figures, and tables must be editable and not inserted as images.
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Expert Consensus

Cover Letter Cover letter must disclose any use of AI tools in manuscript writing, image or graphic production, or data collection and analysis. AI disclosure in the cover letter must include all prompts used, the full prompt used to generate research results, the time and date of the query, and the AI tool name and version.
Abstract A structured abstract is required. Abstract must be 200–350 words. Abstract must be structured. Abstract headings must be Background, Methods, Results, and Conclusions.
Manuscript There is no fixed word limit, but the main text word count excluding the abstract, references, tables, boxes, and figures must be provided at submission. Main text must be organized as Introduction, Methods, a main body with clear recommendations and discussions, and Conclusions. Manuscript must include 3–5 keywords, a highlight box of no more than 300 words using the headings Key recommendations, What was recommended and what is new?, and What is the implication, and what should change now?, and a Contributions section with the specified role headings unless there is only one author.
References References must follow Vancouver style. References must be cited as numbers in round brackets in consecutive order of first appearance, with journal titles abbreviated in Index Medicus style and author names listed as all authors up to three or the first three followed by et al. for more than three.
Figures & Tables Tables are recommended to be provided in separate files, and figures must be provided in separate files. Figure legends are required, and tables must be editable rather than inserted as images.
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Case Series

Cover Letter Cover letter must disclose any use of AI tools in manuscript writing, image or graphical production, or data collection and analysis. Cover letter AI disclosures must include all prompts used, the full prompt used to generate research results, the time and date of each query, and the AI tool name and version.
Abstract Abstract is required. Structured abstract must be 200–350 words. Abstract must be structured. Abstract must use the headings Background, Case Description, and Conclusions.
Manuscript Main text must not exceed 2,500 words excluding references, tables, and figures. Main text must be organized as Introduction, Case Presentation, Discussion, and Conclusions. Manuscript must include 3–5 keywords, a highlight box of no more than 250 words with the sections Key findings, What is known and what is new?, and What is the implication, and what should change now?, and a Contributions section unless there is only one author.
References References must not exceed 35. References must follow Vancouver style. References must be cited as numbers in round brackets in consecutive order, with journal titles abbreviated per Index Medicus and up to three authors listed in full or the first three followed by et al. for more than three authors.
Figures & Tables Figures and tables must not exceed 8 in total. Tables are recommended to be provided in separate files and figures must be provided in separate files. Tables must be editable and numbered consecutively, and figures must be cited in order with accompanying figure legends.
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Case Report

Cover Letter Any use of AI tools must be disclosed in the cover letter, including the prompts used, the time and date of queries, and the AI tool name and version.
Abstract A structured abstract is required. Abstract must be 200–350 words. Abstract must be structured. Abstract headings must be Background, Case Description, and Conclusions.
Manuscript Manuscript must not exceed 2,500 words excluding references, tables, and figures. Main text must be organized as Introduction, Case Presentation, Discussion, and Conclusions. Manuscript must include 3–5 keywords, a highlight box of no more than 250 words using the sections Key findings, What is known and what is new?, and What is the implication, and what should change now?, and a Contributions section unless there is only one author with the specified contribution headings.
References References must not exceed 35. References must follow Vancouver style. References must be cited as numbers in round brackets in consecutive order of first appearance, with up to three authors listed in full and more than three listed as the first three followed by “et al.”
Figures & Tables Figures and tables must not exceed 8 combined. Tables and figures must be provided in separate files. Figures must include legends, and tables must be editable and not submitted as images.
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Brief Report

Cover Letter Cover letter is required only to disclose any use of AI tools in manuscript writing, image or graphical production, or data collection and analysis. Cover letter must disclose any AI tool use and include all prompts used, the full prompt used to generate research results, the time and date of the query, and the AI tool name and version.
Abstract Abstract is required. Abstract must be 200–350 words. Abstract must be unstructured and contain no subheadings. Abstract must not use headings, and 3–5 keywords must be included.
Manuscript Manuscript must not exceed 2,500 words excluding references, tables, and figures. Main text must be unstructured. Manuscript must include 3–5 keywords and an ethical statement indicating whether written consent has been obtained from the subject or parent or guardian.
References References must not exceed 35. References must follow Vancouver style. References must be cited as consecutive numbers in round brackets in order of first appearance, with journal titles abbreviated per Index Medicus and author lists showing all authors if there are up to three or the first three followed by et al. if there are more than three.
Figures & Tables Figures and tables must not exceed 8 in total. Figures must be provided in separate files, and tables are recommended to be provided in separate files. Figure legends are required for figures, and tables must be numbered consecutively and provided in editable tabular format rather than as images.
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Letter To The Editor

Cover Letter Any use of AI tools in manuscript writing, image or graphical production, or data collection and analysis must be disclosed in the cover letter with the prompts, query time and date, and tool name and version.
Abstract Abstract is not required.
Manuscript Manuscript must not exceed 1,000 words excluding references, tables, and figures. Main text must be unstructured. No abstract or keywords are required.
References References must not exceed 10. References must follow Vancouver style. Citations must be numbered in round brackets in order of first appearance, with up to three authors listed in full and more than three listed as the first three followed by “et al.”.
Figures & Tables No more than 1 figure or table is allowed. Figures must be provided in separate files and tables are recommended to be provided in separate files. Figures and tables must be numbered consecutively in the order they are first mentioned in the text.
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Recent Publications

B cell-driven refractory hemocytopenia in immune checkpoint inhibitor therapy: a report of two cases

Feng Li, Chunyan Wang, Guohua Yao, Shaotong Zhang, Qian Hu, Zhenyu Ju, Wenhua Liang

10.21037/tlcr-2025-939
View Publication

Integrated management of immunotherapy and radiotherapy for patients with metastatic non-small cell lung cancer: a narrative review of current landscape and future directions

Xinquan Liang, Fengxue Li, Yingying Zhang, Pingping Hu, Tiantian Tian, Yan Zhang, Ning Liang, Guodong Deng, Fangjie Ding, Xin Liu, Lili Qiao, Jiandong Zhang

10.21037/tlcr-2026-1-0018
View Publication

Adjuvant chemotherapy for completely resected stage IB–IIA non-small cell lung cancer according to the AJCC 8th edition staging system: a real-world retrospective cohort study based on the SEER database

Zewen Sun, Changtai Zhao, Kexin Feng, Geyun Chang, Jingwei Zhang, Yan Ju, Fan Yang, Xiang Yan, Xiao Li

10.21037/tlcr-2025-1-1403
View Publication

Effect of cold ischemia time and storage temperature on anaplastic lymphoma kinase (ALK) expression in surgically resected lung cancer specimens

Ryuichi Yoshimura, Naoki Yanagawa, Noriyuki Yamada, Makoto Tomoyasu, Wataru Shigeeda, Yuka Kaneko, Ryotaro Endo, Hironaga Kanno, Hiroyuki Deguchi, Hajime Saito

10.21037/tlcr-2025-1-1338
View Publication

A radiomics nomogram integrated with radiological features for preoperative prediction of lung nodule invasiveness: comparison with Lung-RADS

Siwei Miao, Zhaojie Han, Fei Wang, Shengwei Liu, Ying Li, Kun Li, Hongqian Wang, Shuaixiang Gao, Xiaolin Xiong, Hao Luo, Chencui Huang, Yang Qiu, Peng Wang, Haidong Wang

10.21037/tlcr-2025-1083
View Publication

Frequently asked questions

How long does it take to publish?

In-house review takes 1-3 weeks. External peer review takes 1-3 months. Publication ahead of print occurs within 1 month after acceptance with APC payment received. Formal publication occurs within 1-3 months after acceptance with APC payment received. Original Articles are listed as priority.

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Is a cover letter required?

Authors must disclose any use of AI tools in the cover letter, Materials and Methods, and Acknowledgment.

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What are the publication costs?

Research Topics

Lung Cancer Treatments and Mutations Lung Cancer Diagnosis and Treatment Lung Cancer Research Studies Cancer Immunotherapy and Biomarkers Radiomics and Machine Learning in Medical Imaging Cancer Genomics and Diagnostics Neuroendocrine Tumor Research Advances RNA modifications and cancer Pleural and Pulmonary Diseases Colorectal Cancer Treatments and Studies Medical Imaging and Pathology Studies Occupational and environmental lung diseases Peptidase Inhibition and Analysis Advanced Radiotherapy Techniques Tracheal and airway disorders Immunotherapy and Immune Responses Gastric Cancer Management and Outcomes Brain Metastases and Treatment Ferroptosis and cancer prognosis Cancer therapeutics and mechanisms Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Cancer Cells and Metastasis Medical Imaging Techniques and Applications Cancer-related molecular mechanisms research HER2/EGFR in Cancer Research

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