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WIREs Mechanisms Of Disease

WIREs Mechanisms of Disease publishes invited, peer-reviewed review articles by experts in genetics/genomics/epigenetics, molecular and cellular physiology, stem cells and development, environmental factors, biomedical engineering, and computational models. The journal is indexed in MEDLINE/PubMed, the Web of Science, Chemical Abstracts Service, and Scopus.

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Impact Factor 4.9
Quartile Q1
Open Access Type Hybrid
ISSN 2692-9368
eISSN 2692-9368
Invitation Only Yes
Cost Range $4,880 USD / £3,330 GBP / €4,040 EUR APC for Open Access articles if accepted and published

Submission Instructions

WIREs Mechanisms Of Disease is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Overview

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must be limited to 8,000 words and 15 pages. A full-color graphical or visual abstract must be included under the text abstract and in the online Table of Contents, and any AI tool use in developing the manuscript must be transparently described in the Methods or Acknowledgements section.
References References and citations must use APA style. In-text citations must include the author surname or surnames and year of publication, and the reference list must be ordered alphabetically by author surname.
Figures & Tables No more than 12 figures may be included.
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Advanced Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must be limited to 6,000 words and 10 pages. A full-color graphical or visual abstract must be included under the text abstract and in the online Table of Contents, and any use of AI to develop part of the manuscript must be described in detail in the Methods or Acknowledgements section.
References References and citations must use APA style. In-text citations must include author surname or surnames and year of publication, and the reference list must be ordered alphabetically by author surname.
Figures & Tables No more than 8 figures may be included. Figures must be optimized for color-blind and visually impaired readers, use a color-blind-safe high-contrast palette, replace red with magenta in fluorescent red-green images, and captions must explain figures sufficiently for screen readers.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must be limited to 6,000 words and 10 pages. A full-color graphical or visual abstract must be included under the text abstract and in the online Table of Contents, and any AI tool use in developing the manuscript must be transparently described in the Methods or Acknowledgements section.
References References and citations must use APA style. In-text citations must include author surname or surnames and year of publication, and the reference list must be ordered alphabetically by author surname.
Figures & Tables No more than 8 figures may be included. Figures must be optimized for color-blind and visually impaired readers, including captions that support screen readers and use of a color-blind safe, high-contrast palette.
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Focus Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must be limited to 4,000 words and 6 pages. A full-color graphical or visual abstract must be included under the text abstract and in the online Table of Contents, and any AI use in developing the manuscript must be disclosed in the Methods or Acknowledgements section.
References References and citations must use APA style. In-text citations must include author surname or surnames and year of publication, and the reference list must be ordered alphabetically by author surname.
Figures & Tables No more than 6 figures may be included. Figures must be optimized for accessibility, including use of a color-blind-safe high-contrast palette, replacing red with magenta in fluorescent red-green images, and providing captions that can be understood by screen readers.
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Perspective

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must be limited to 3,000 words and 5 pages. If AI tools were used to develop any portion of the manuscript, their use must be described transparently and in detail in the Methods or Acknowledgements section.
References References and citations must use APA style. In-text citations must include author surname or surnames and year, and the reference list must be ordered alphabetically by author surname.
Figures & Tables No more than 4 figures may be included.
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Primer

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must be limited to 3,000 words and 4 pages. A full-color graphical or visual abstract must be included under the text abstract and in the online Table of Contents, and any AI tool use in developing the manuscript must be transparently described in the Methods or Acknowledgements section.
References References and citations must use APA style. In-text citations must include author surname or surnames and year of publication, and the reference list must be ordered alphabetically by author surname.
Figures & Tables No more than 3 figures may be included. Figures must be optimized for accessibility using a color-blind-safe high-contrast palette, with red replaced by magenta in fluorescent red-green images, and captions must explain the figures sufficiently for screen readers.
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Recent Publications

Issue Information

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10.1002/wsbm.70006
View Publication

Nager Syndrome Revisited: Integrating In Vivo and In Vitro Models to Decipher SF3B4 ‐Dependent Tissue Coordination

Jingru Qin, Zulvikar Syambani Ulhaq, William Ka Fai Tse

10.1002/wsbm.70007
View Publication

Issue Information

-

10.1002/wsbm.1652
View Publication

SARS ‐ CoV ‐2: A Liver Brief

Youness Limami, Hicham Wahnou, Martin Ndayambaje, Soufyane Hba, Oumaima Chgari, Mounia Ammara, Riad El Kebbaj, Abdallah Naya, Mounia Oudghiri, Raphaël Emmanuel Duval

10.1002/wsbm.70005
View Publication

Anna Karenina Principle, Immune‐Oncology‐Microbiome Trio and Cancer Microbiome Therapy

Zhanshan (Sam) Ma

10.1002/wsbm.70004
View Publication

Frequently asked questions

How long does it take to publish?

Median submission to first decision: 135 days; median submission to acceptance: 191 days; median acceptance to publication: 19 days.

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What are the publication costs?

Open Access option: APC of $4,880 USD / £3,330 GBP / €4,040 EUR if accepted and published.

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Research Topics

Diverse Scientific and Economic Studies Human auditory perception and evaluation Educational Robotics and Engineering Mast cells and histamine T-cell and B-cell Immunology Gut microbiota and health Neurogenesis and neuroplasticity mechanisms Pluripotent Stem Cells Research Immune Cell Function and Interaction 3D Printing in Biomedical Research Neuroinflammation and Neurodegeneration Mechanisms Reproductive Biology and Fertility RNA Research and Splicing Bioinformatics and Genomic Networks Epigenetics and DNA Methylation Cancer Cells and Metastasis Gastrointestinal motility and disorders Cellular Mechanics and Interactions Ovarian function and disorders Angiogenesis and VEGF in Cancer Nerve injury and regeneration Gene Regulatory Network Analysis CRISPR and Genetic Engineering Single-cell and spatial transcriptomics Immune cells in cancer