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The AAPS Journal

The AAPS Journal is an official journal of the American Association of Pharmaceutical Scientists, publishing innovative research impacting human and veterinary therapeutics. It is a premier journal among pharmaceutical scientists for disseminating high-quality content, has an average first decision time of 25 days, offers international readership with over 364,000 downloads per year, and does not levy submission or publication charges unless choosing Open Choice.

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Subject Pharmacology & Pharmacy
Impact Factor 3.7
Quartile Q2
Open Access Type Hybrid
ISSN 1550-7416
eISSN 1550-7416
Invitation Only No
Cost Range Open access publication requires an APC of £3190.00 GBP / $5090.00 USD / €3990.00 EUR. Subscription publishing has no APC charges.

Submission Instructions

The AAPS Journal accepts the following article types. Click on an article type to view submission instructions.

Reviews

Cover Letter A cover letter is required. It must state documented review and approval for studies involving people, medical records, or human tissues, compliance with local, national, ethical, and regulatory principles for animal studies, and trial registration information for controlled clinical trials.
Abstract An abstract is required. The abstract must be 250 words or fewer. Unstructured.
Manuscript The recommended manuscript length is 5000 words. An Introduction section is required. The manuscript must include no more than 5 keywords and a conclusion that is a brief paragraph of 3 to 4 sentences.
References No more than 100 references. Vancouver. References must be numbered consecutively in the order cited in the text and cited with Arabic numerals in parentheses.
Figures & Tables The suggested maximum combined count of tables and figures is 10. Figures and tables must be submitted as separate files rather than embedded in the manuscript body. Figures must be numbered in one consecutive series of Arabic numerals, and tables must be numbered with Roman numerals.
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Mini-Reviews

Cover Letter A cover letter is required. The cover letter must state documented review and approval for studies involving people, medical records, or human tissues, trial registration information for controlled clinical trials, and compliance with local, national, ethical, and regulatory principles for experimental animal studies.
Abstract An abstract is required. Abstract must be 250 words or less. Unstructured.
Manuscript Recommended length is 2500 words. An Introduction section is required. Provide no more than 5 keywords, and use a brief conclusion paragraph of 3 to 4 sentences summarizing the findings.
References Mini-Reviews may include a maximum of 50 references. Vancouver. References must be numbered consecutively in the order cited in the text and cited with Arabic numerals in parentheses.
Figures & Tables The combined total of tables and figures must not exceed 6. Figures and tables are submitted separately rather than embedded in the manuscript body. Figures must be numbered consecutively in Arabic numerals and table data must be placed in separate cells.
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Original Research Papers

Cover Letter A cover letter is required. It must include trial registration information for controlled clinical trials, statements of review board approval for studies involving people, medical records, or human tissues, and statements of compliance for investigations using experimental animals.
Abstract An abstract is required. 250 words or less. Unstructured paragraph form. Introduction, Methods and Materials, Results and Discussion, and Conclusion.
Manuscript Recommended length is 5000 words. Introduction, Materials and Methods, Results, Discussion, and Conclusion. An Introduction section is required, and up to 5 keywords must be provided.
References No more than 100 references. Vancouver. References must be numbered consecutively in the order cited in the text and cited with Arabic numerals in parentheses.
Figures & Tables A maximum combined total of 10 tables and figures is allowed. Figures and tables must be submitted separately rather than embedded in the manuscript body. Tables must be numbered with Roman numerals, figures with consecutive Arabic numerals, and figure captions must be collected in a separate 'Legend to Figures' section.
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Brief Technical Notes

Cover Letter A cover letter is required. It must indicate whether supplementary files should be evaluated by reviewers only or included for review and published with the article if accepted.
Abstract Abstract requirements are not specified.
Manuscript The main text is recommended to be 1200 words. The main text must be organized as Introduction, Materials and Methods, Results, Discussion, and Conclusion. The manuscript should include no more than 5 keywords, use continuous line numbers, and use a conclusion consisting of a brief 3 to 4 sentence paragraph.
References No more than 20 references may be used. Vancouver. References must be numbered consecutively in the order cited in the text and cited with Arabic numerals in parentheses.
Figures & Tables The combined total of tables and figures must not exceed 6. Figures and tables must be uploaded separately rather than embedded in the manuscript. Tables must be numbered with Roman numerals, figures must be numbered consecutively with Arabic numerals, and figure captions must be provided in a separate 'Legend to Figures' section.
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Rapid Communications

Cover Letter A cover letter is required. The cover letter must state the justification for rapid communication.
Abstract An abstract is required. The abstract must be 250 words or less. Unstructured.
Manuscript The recommended word count is 1200 words. The main text must be organized as Introduction, Materials and Methods, Results, Discussion, and Conclusion. Provide up to 5 keywords, include a brief conclusion of 3 to 4 sentences, and document any use of a large language model in the Methods section or another suitable part if there is no Methods section.
References No more than 20 references may be included. Vancouver style. References must be numbered consecutively in the order cited, cited in the text with Arabic numerals in parentheses, and journal abbreviations must conform to Vancouver style.
Figures & Tables The combined total of tables and figures must not exceed 6. Figures and tables are submitted separately as individual files rather than embedded in the manuscript body. Tables must be numbered with Roman numerals and figures with consecutive Arabic numerals, with figure captions placed in a separate 'Legend to Figures' section.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript The title page must be submitted as a separate file and include the article title, author names with full first names and no degrees, each author’s affiliation, a running head of fewer than 50 characters, and the corresponding author’s complete mailing address, telephone number, fax number, and e-mail address.
References Vancouver style. References must be numbered consecutively in the order cited in the text and cited with Arabic numerals in parentheses.
Figures & Tables Electronic artwork must be submitted online via Editorial Manager, and tables must be created in Microsoft Word table format. Tables must be numbered with Roman numerals, have titles centered above them, and use superscript lowercase letters for footnotes, while figures must be numbered consecutively in Arabic numerals and have captions collected in a separate 'Legend to Figures' section.
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Recent Publications

Guiding the Molnupiravir Tablet Formulation Using Physiologically Based Biopharmaceutics Modeling and Successfully Establishing Dissolution Safe Space

Thomas Morrow, Nicole Jarvi, Madeline Halota, Cheng Sun, Prapti Kafle, Rachel King, Grace Okoh, Sanjaykumar Patel, Tycho Heimbach

10.1208/s12248-026-01249-4
View Publication

Correction: Nanotechnology-enhanced Natural Products for Cancer Chemoprevention: Molecular Mechanisms and Clinical Translation

Rajat Nath, Sibashish Kityania, Deepa Nath, Jayanta Kumar Patra, Emran Habibi, Satyajit D. Sarker, Anupam Das Talukdar, Lutfun Nahar

10.1208/s12248-026-01266-3
View Publication

Quantitative Estimation of Clinical Intrasubject Variability of a Pharmacokinetic Parameter

Hao-Jui Hsu, Katrina Casteel, Samuel Yang, Vivek Purohit, Vu Le, Kazuko Sagawa

10.1208/s12248-026-01264-5
View Publication

Targeting Pyruvate Kinase M2: Signal Transduction Pathways and Exploration of Cancer Therapeutic Strategies

Jiaxing Wang, Wenyu Zhang, Nana Shen, Pan Li, Wentao Xie, Shuya Wang, Ye Cheng, Lin Zhao, Yang Yang, Huadong Zhao

10.1208/s12248-026-01261-8
View Publication

Context-of-use–Guided Development and Validation of a Transthyretin Immunoassay: A Framework for Biomarker Assay Design

Tanya Watanabe, John Canfield, Erin Anderson, Leighla Tayefeh, John L. Allinson, Nicholas J. Viney, Joel A. Mathews

10.1208/s12248-026-01262-7
View Publication

Frequently asked questions

How long does it take to publish?

Published online first after receipt of author corrections to page proofs. Meeting Notices should be submitted two to three months prior to the meeting.

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Is a cover letter required?

A cover letter is recommended, but not required. A cover letter is required for Rapid Communications. Trial registration information and human or animal ethics statements are required in the cover letter for applicable studies.

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What are the publication costs?

Open access publication requires an APC of £3190.00 GBP / $5090.00 USD / €3990.00 EUR. Subscription publishing has no APC charges.

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Research Topics

Biosimilars and Bioanalytical Methods Monoclonal and Polyclonal Antibodies Research Drug Solubulity and Delivery Systems Statistical Methods in Clinical Trials Drug Transport and Resistance Mechanisms Pharmacogenetics and Drug Metabolism Protein purification and stability Pharmaceutical studies and practices Computational Drug Discovery Methods Advanced Drug Delivery Systems RNA Interference and Gene Delivery Receptor Mechanisms and Signaling Inhalation and Respiratory Drug Delivery Analytical Chemistry and Chromatography Crystallization and Solubility Studies Pharmacological Effects and Toxicity Studies Nanoparticle-Based Drug Delivery Antibiotics Pharmacokinetics and Efficacy Analytical Methods in Pharmaceuticals CAR-T cell therapy research Advanced Biosensing Techniques and Applications Health Systems, Economic Evaluations, Quality of Life Viral Infectious Diseases and Gene Expression in Insects Pharmaceutical Economics and Policy Advancements in Transdermal Drug Delivery

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