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ACS Chemical Neuroscience

ACS Chemical Neuroscience reports chemical, biological, biophysical, and bioengineering research on the nervous system and neurological disorders.

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Subject Neurosciences
Impact Factor 3.9
Quartile Q2
Open Access Type Hybrid
ISSN 1948-7193
eISSN 1948-7193
Invitation Only No
Cost Range Article publishing charges vary by journal and route; a zero-embargo green open access article development charge is a flat fee of $2,500 USD due after acceptance, and hybrid journals offer a $2,000 USD discount for 12-month embargo open access. Diamond open access is free for authors in selected journals.

Submission Instructions

ACS Chemical Neuroscience accepts the following article types. Click on an article type to view submission instructions.

Article

Cover Letter A cover letter is required and must include a short lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry. The cover letter must contain a short lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry.
Abstract An abstract is required for Articles. The abstract must be unreferenced and 250 words or less. The abstract must be unstructured and written in complete sentences without subheadings. No abstract headings are required.
Manuscript The introduction should be approximately 1000 words for an Article. Articles must include the headed sections Introduction, combined Results and Discussion, and Methods, with Methods placed at the end following Results and Discussion. The manuscript must include a graphical Table of Contents entry, six keywords below the abstract, and an AI-use disclosure in the manuscript when AI tools for text or image generation were used.
References Articles generally include approximately 50 references. References must be numbered with Arabic numerals in the order of first citation, cited in the text at the appropriate locations, include titles, and be compiled in a list at the end of the manuscript.
Figures & Tables Articles generally include 8–10 display items consisting of figures, tables, and schemes. Figures should be embedded in the text at the point of relevance. A graphical Table of Contents entry must be provided on the last page of the manuscript and labeled “For Table of Contents Only.”
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Letter

Cover Letter A cover letter is required with every submission. Cover letter should include a short lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry.
Abstract An unreferenced abstract is required for Letters. Abstract must be less than 150 words. Abstract must be unstructured and written in complete sentences without subheadings. Abstract must not contain any headings.
Manuscript Letter must be approximately 4500 words or less, including the abstract, body text, methods, references, and figure or scheme legends. Letter must include unheaded Introduction and combined Results and Discussion sections plus a headed Methods section at the end of the manuscript. Manuscript must include a graphical Table of Contents entry and six keywords below the abstract, and AI tool use should be disclosed in the Acknowledgments or Methods section as applicable.
References Letter should contain approximately 30 references. References must be listed together at the end of the manuscript and numbered with Arabic numerals in order of first citation in the text.
Figures & Tables Letter should contain 4–6 display items, including figures, tables, and schemes. Figures should be embedded in the text at the point of relevance. A graphical Table of Contents entry must be included and labeled “For Table of Contents Only” on the last page of the submitted manuscript.
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Review

Cover Letter A cover letter is required and must include a lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry. The cover letter must include a lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry.
Abstract An abstract is required for Reviews. The abstract must be unreferenced and 250 words or less. The abstract must be unstructured and written in complete sentences without subheadings.
Manuscript Reviews should contain fewer than 5000 words. Reviews must include a graphical Table of Contents entry, and authors should provide six keywords below the abstract.
References Reviews should contain approximately 100 references. References must be listed at the end of the manuscript, numbered with Arabic numerals in order of first citation, cited in the text by the corresponding numbers, and include titles.
Figures & Tables Reviews are strongly encouraged to use 3–5 figures to illustrate key concepts. Figures should be embedded in the text at the point of relevance. Reviews must include a graphical Table of Contents entry consisting of a colorful figure representing the topic of the review, and permission must be obtained for reproduced or adapted graphics.
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Perspective

Cover Letter A cover letter is required with every submission. The cover letter must include a short lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry.
Abstract Abstract requirements are not specified.
Manuscript Perspective articles are expected to occupy approximately 4–7 pages of printed text. The manuscript must include a graphical Table of Contents entry and six keywords displayed below the abstract.
References Perspective submissions may contain up to 60 references. References must be numbered with Arabic numerals in the order of first citation in the text and compiled in a list at the end of the manuscript.
Figures & Tables Perspective submissions may contain up to 7 figures. Figures should be embedded in the text at the point of relevance. A graphical Table of Contents entry is required, and permission must be obtained for graphics reproduced or adapted from other sources.
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Viewpoint

Cover Letter A cover letter is required with every submission and must include a short lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry. Cover letter must include a short lay summary of approximately 150 words describing the significance of the study for a broad audience at the level of an undergraduate in biochemistry.
Abstract An abstract is required for Viewpoints. Abstract should be brief at 1–3 sentences and ideally less than 200 words. Abstract must be unstructured and written in complete sentences without subheadings. Abstract must contain no headings and must not include any references.
Manuscript Viewpoint articles should occupy approximately 1200 words and must not exceed 3 printed pages. Viewpoints should begin with a brief abstract. Manuscript should include a graphical summary for the table of contents, six keywords below the abstract, and AI tool use disclosures in the Acknowledgments or Methods section when applicable.
References Viewpoint articles must be limited to five references. References must be numbered with Arabic numerals in order of first citation, cited at the appropriate locations in the text, and compiled in a list at the end of the manuscript.
Figures & Tables Viewpoints should include at least one figure and can usually accommodate two figures. Figures should be embedded in the text at the point of relevance, and the table-of-contents graphic should be provided on the last page of the manuscript. A graphical summary for the table of contents is required and must be labeled “For Table of Contents Only.”
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Recent Publications

Decreased Sphingosine 1-Phosphate Levels in the Prefrontal Cortex of Mice Susceptible to Repeated Social Defeat Stress

Katsuya Morito, Suzumi Kimura, Saki Fujisawa, Yuki Nishimura, Kentaro Takayama

10.1021/acschemneuro.6c00163
View Publication

Alzheimer’s Disease: A Review of Molecular Mechanisms and Interventions Targeting Aβ-Binding Receptors

Mengke Jia, Jinfei Mei, Yvning Guan, Zhi Wang, Hongqi Ai

10.1021/acschemneuro.6c00207
View Publication

5-HT 4 Receptor Ligand RS67333 Modulates Striatal Acetylcholine and Dopamine Release via the Inhibition of Acetylcholinesterase

Qinbo Qiao, Wenhui Wu, Stephanie J. Cragg

10.1021/acschemneuro.6c00342
View Publication

Microbes and Microbial Chemical Matter in the Seeding of Alzheimer’s Disease: Prospects for Orthogonal Therapies

Naveen Kumar, Venkateswarlu Yarlagadda

10.1021/acschemneuro.6c00255
View Publication

Emerging Promise of Sulforaphane in Autism: A Comprehensive Review of Its Therapeutic Potential and Mechanisms

Xinming Zhang, Qi He, Yuan yuan Zhu, George H. Lorimer, Hasan Bayram, Reza A. Ghiladi, Jun Wang

10.1021/acschemneuro.6c00282
View Publication

Frequently asked questions

How long does it take to publish?

Median 6.9 days from submission to first editorial decision, 35 days from submission to first decision with peer review, 83.1 days from submission to accept, and 10.2 days from accept to ASAP publication.

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Is a cover letter required?

A cover letter is expected to include a short approximately 150-word lay summary describing the significance of the study for a broad audience.

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What are the publication costs?

Immediate open access in ACS journals requires an article publishing charge. Zero-embargo green open access has a flat article development charge of $2,500 USD due after acceptance. Hybrid journals offer a $2,000 USD discount for 12-month embargo open access. Diamond open access is free for authors in selected journals.

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Research Topics

Alzheimer's disease research and treatments Neuroscience and Neuropharmacology Research Receptor Mechanisms and Signaling Cholinesterase and Neurodegenerative Diseases Neurotransmitter Receptor Influence on Behavior Parkinson's Disease Mechanisms and Treatments Computational Drug Discovery Methods History and advancements in chemistry Neuroinflammation and Neurodegeneration Mechanisms Nicotinic Acetylcholine Receptors Study Protein Structure and Dynamics Neuropeptides and Animal Physiology Pharmacological Receptor Mechanisms and Effects Tryptophan and brain disorders Ion channel regulation and function Academic Writing and Publishing Supramolecular Self-Assembly in Materials Photoreceptor and optogenetics research Lipid Membrane Structure and Behavior Pain Mechanisms and Treatments Prion Diseases and Protein Misfolding Electrochemical sensors and biosensors Neuroscience and Neural Engineering Mitochondrial Function and Pathology Neurological disorders and treatments

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