Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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American Journal of Physiology-Lung Cellular and Molecular Physiology

American Journal of Physiology-Lung Cellular and Molecular Physiology publishes research on lung physiology, cellular and molecular mechanisms, and respiratory disease. The journal includes research articles, reviews, editorials, editorial focus content, and articles in press. It is published by the American Physiological Society.

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Subject Respiratory System

Impact Factor 3.5

Quartile Q1

Open Access Type Closed

ISSN 1040-0605

eISSN 1522-1504

Invitation Only No

Submission Instructions

American Journal of Physiology-Lung Cellular and Molecular Physiology accepts the following article types. Click on an article type to view submission instructions.

Research Article

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract is required. Abstract must not exceed 250 words.

Manuscript Manuscript must include Materials and Methods and Results sections. Manuscript must include a New & Noteworthy summary limited to 75 words, up to 5 keywords without abbreviations, and a Data Availability Statement.

References References must follow Vancouver style. References must be listed in numerical order as cited in the text, and only published, accepted, or preprint articles may appear in the reference list.

Figures & Tables Tables must be submitted in Word table format and not as tabbed text or embedded images.

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Review Article

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract is required. Abstract must not exceed 250 words.

Manuscript Review Articles must not exceed 6,000 words. Review Articles may include up to 5 keywords, and abbreviations must be avoided in keywords.

References References must follow Vancouver style. References must be listed in numerical order as cited in the text.

Figures & Tables Review Articles may include up to 6 figures. Tables must be submitted in Word table format and not as tabbed text or embedded images.

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Systematic Review

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract is required. Abstract must not exceed 250 words.

Manuscript Systematic Reviews must indicate in the title that they are a systematic review or meta-analysis of the literature and must report the search strategy, inclusion and exclusion criteria, extracted information characteristics, and risk of bias and limitations, with additional meta-analysis methods and consistency measures defined if applicable. Systematic Reviews may include up to 5 keywords, and keywords must avoid abbreviations.

Figures & Tables Tables must be submitted in Word table format and not as tabbed text or embedded images.

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Methods And Resources

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract is required. Abstract must not exceed 250 words.

Manuscript Methods And Resources manuscripts must describe the method in sufficient detail to enable others to implement or replicate it, and extensive technical details and mathematical derivations may be placed in an Appendix if needed.

References References must follow Vancouver style. References must be listed in numerical order as cited in the text.

Figures & Tables Tables must be submitted in Word table format and not as tabbed text or embedded images.

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Short Report

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract is required. Abstract must not exceed 250 words.

Manuscript Manuscript must not exceed 4,000 words excluding references and figure legends. Manuscript must include a title page. Manuscript may include up to 5 keywords, and keywords must avoid abbreviations.

References References must follow Vancouver style. References must be listed in numerical order as cited in the text.

Figures & Tables Short Reports may include up to 4 figures or tables, excluding additional online materials. Tables must be submitted in Word table format and not as tabbed text or embedded images.

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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract must not be included.

Manuscript Manuscript must not exceed 1,000 words, excluding references. Letter must respond to work previously published in the journal and must not include new or unpublished data. Title must be clear and unique and must not quote or reuse the original article title.

References Letter may include up to 10 references, including the highlighted article. References must follow Vancouver style. References must be listed in numerical order as cited in the text.

Figures & Tables Figures and tables must not be included.

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Education Research

Cover Letter Cover Letter requirements are not specified.

Abstract Abstract requirements are not specified.

Manuscript Manuscript must include a title page, Materials and Methods, Results, Acknowledgments, Grants, Disclosures, and author contributions, with a SUPPLEMENTAL MATERIAL section after the Discussion section if supplemental files are cited. Title page must include a title of no more than 160 characters, a running head of no more than 60 characters, full author names, affiliations, and the corresponding author's contact information.

References References must follow Vancouver style. References must be listed in numerical order as cited in the text, include only published or accepted articles and preprints, and exclude unpublished observations and personal communications from the reference list.

Figures & Tables Figure legends must clearly describe each figure, define all statistical symbols and abbreviations, include N values and applicable P values, and tables must be submitted in Word table format rather than as tabbed text or embedded images.

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Recent Publications

Increased lung cell susceptibility to injury due to autophagic overload after exposure to nanoparticles

Arnold Sipos, Kwang-Jin Kim, Juan R. Alvarez, Edward D. Crandall

10.1152/ajplung.00362.2025

View Publication

VCO ₂ : The Essential Underpinning to Homeostatic Control of Breathing

Jerome A. Dempsey, Donald R. McCrimmon

10.1152/ajplung.00141.2026

View Publication

Piecing Together the Alveolar–Capillary Unit: Arterial – Venous Capillary Polarization

Susan M. Majka, Terren K. Niethamer, Nunzia Caporarello, Hannah F. Thorndyke, Geremy Clair, James D. West, Harry Karmouty-Quintana, Cristina M. Alvira

10.1152/ajplung.00101.2026

View Publication

Correction for Wang et al., volume 301, 2011, p. L197–L206

10.1152/ajplung.00048.2011_cor

View Publication

Advances in Human Lung Disease Models: Stem Cell-based Platforms for Modeling Airway and Alveolar Disease.

Daniel J. Wallman, Sinem Koc-Gunel, Robert E Hynds, Amy L. Ryan, Ruth Olmer

10.1152/ajplung.00092.2026

View Publication

Frequently asked questions

How long does it take to publish?

44 days to first decision; 14.6 days to ahead-of-print publication; 2.1 months to final publication

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Is a cover letter required?

A pre-submission inquiry is encouraged for Review Articles; no cover letter requirement is stated for the other article types listed.

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Research Topics

Neonatal Respiratory Health Research Asthma and respiratory diseases Neuroscience of respiration and sleep Respiratory Support and Mechanisms Nitric Oxide and Endothelin Effects Pulmonary Hypertension Research and Treatments Immune Response and Inflammation Congenital Diaphragmatic Hernia Studies Chronic Obstructive Pulmonary Disease (COPD) Research Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Ion channel regulation and function Inhalation and Respiratory Drug Delivery Cystic Fibrosis Research Advances Ion Transport and Channel Regulation Receptor Mechanisms and Signaling Air Quality and Health Impacts Eicosanoids and Hypertension Pharmacology Cell Adhesion Molecules Research Neutrophil, Myeloperoxidase and Oxidative Mechanisms Respiratory and Cough-Related Research Neuropeptides and Animal Physiology Protease and Inhibitor Mechanisms Heme Oxygenase-1 and Carbon Monoxide Tracheal and airway disorders Cancer, Hypoxia, and Metabolism