AJ

American Journal of Physiology-Renal Physiology

American Journal of Physiology-Renal Physiology is a journal focused on renal physiology and kidney-related research. The journal highlights current issues, articles in press, collections, calls for papers, and multiple article categories including research articles, reviews, editorials, and fast track submissions.

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Subject Urology & Nephrology
Impact Factor 3.4
Quartile Q1
Open Access Type Open
ISSN 1931-857X
eISSN 1522-1466
Invitation Only No
Cost Range Open access without APCs in participating journals under the Subscribe to Open program; a flat fee per article is also referenced for institutional participation.

Submission Instructions

American Journal of Physiology-Renal Physiology accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter Cover letter is required to disclose whether the manuscript has been posted to a preprint server and to identify the preprint server and associated DOI or DOIs. Cover letter must disclose any preprint posting and identify the preprint server and associated DOI or DOIs.
Abstract Abstract is required for Research Articles. Abstract must be limited to 250 words.
Manuscript No word limit applies. Manuscript must include an introduction, methods, results, and discussion. Manuscript must include a New & Noteworthy summary limited to 75 words, up to 5 keywords, author contributions, disclosures, a Data Availability Statement, and AI use disclosures in the Materials and Methods or Acknowledgments when applicable.
References No reference limit applies. References must follow Vancouver style. References must be listed in numerical order as cited in the text, include only published or accepted articles and preprints, and exclude unpublished observations and personal communications from the reference list.
Figures & Tables No figure or table limit applies. New submissions must include figures and tables with the manuscript, while tables must be provided in Word table format rather than as tabbed text or embedded images. A graphical abstract is required for AJP-Renal Physiology and must be submitted at revision using Template A and be unique from other figures.
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Mini-Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract A one-paragraph abstract is required. Abstract must be limited to 250 words. Abstract must be unstructured as a single paragraph.
Manuscript Mini-Reviews should be approximately 3,000 words excluding references. Manuscript may include up to 5 keywords.
References No reference limit applies. References must follow Vancouver style. References must be listed in numerical order as cited in the text, and only published, accepted, or preprint articles may appear in the reference list.
Figures & Tables Mini-Reviews may include 1–3 figures and/or tables. Previously published figures may be included only if permission is obtained from the copyright holder and the source is acknowledged.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A one-paragraph abstract is required. Abstract must be limited to 250 words. Abstract must be unstructured as a single paragraph.
Manuscript Manuscript must not exceed 6,000 words. Manuscript may include up to 5 keywords.
References No reference limit applies. References must follow Vancouver style. References must be listed in numerical order as cited in the text.
Figures & Tables Up to 6 figures are allowed.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract A one-paragraph abstract is required. Abstract must be limited to 250 words. Abstract must be unstructured as a single paragraph.
Manuscript No word limit applies. Title must identify the article as a systematic review or meta-analysis, and the manuscript must report study registration, search strategy, inclusion and exclusion criteria, extracted information characteristics, any meta-analysis methodology, and risk of bias and search or analysis limitations. Manuscript may include up to 5 keywords, and any use of AI in manuscript preparation must be disclosed in the Acknowledgments or in Materials and Methods if used in the research process.
References References must follow Vancouver style. References must be listed in numerical order as cited in the text, include only published or accepted articles and preprints in the reference list, and exclude unpublished observations and personal communications from the reference list.
Figures & Tables No figure or table limit applies. Tables must be submitted in Word table format rather than as tabbed text or embedded images.
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Short Reports

Cover Letter Cover Letter requirements are not specified.
Abstract A one-paragraph abstract is required. Abstract must be limited to 250 words. Abstract must be unstructured as a single paragraph.
Manuscript Manuscript must not exceed 4,000 words excluding references and figure legends. Manuscript must include New & Noteworthy.
References No reference limit applies. References must follow Vancouver style. References must be listed in numerical order as cited in the text, and only published or accepted articles may appear in the reference list.
Figures & Tables Manuscript may include up to 4 figures or tables. Short Reports supplemental material files must be uploaded to a repository and linked in the manuscript. A graphical abstract is required and must be unique from the other figures.
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Review: Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract A one-paragraph abstract is required. Abstract must be limited to 250 words. Abstract must be unstructured as a single paragraph.
Manuscript Manuscript must be 10,000 to 25,000 words. Manuscript may include up to 5 keywords, and any use of AI or AI-assisted tools in manuscript preparation must be disclosed in the Acknowledgments with the specified statement.
References References must follow Vancouver style. References must be listed in numerical order as cited in the text, include only published or accepted articles and preprints in the reference list, and exclude unpublished observations and personal communications from the reference list.
Figures & Tables No figure or table limit applies. Tables must be submitted in Word table format rather than as tabbed text, embedded images, or tables with shading, color highlights, or embedded graphics.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is not required.
Manuscript Letter must be limited to 1,000 words excluding references. Letter must respond to work previously published in the journal and have a clear, unique title that does not quote or reuse the original article's title.
References Letter may include no more than 10 references. References must follow Vancouver style. References must be listed in numerical order as cited in the text, and only published, accepted, or preprint articles may appear in the reference list.
Figures & Tables Figures and tables are not allowed.
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Replies

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be included.
Manuscript Manuscript must be limited to 1,000 words excluding references. Title must use the format "Reply to [Last Name] et al.". Replies may not include new or unpublished data.
References References may not exceed 10. References must follow Vancouver style. References must be listed in numerical order as cited in the text, and only published or accepted articles may appear in the reference list.
Figures & Tables Figures & Tables requirements are not specified.
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Recent Publications

Sex Differences in the Renal T Cell Profile in DOCA-Salt Hypertension are Independent of MR Activation and Increases in Blood Pressure

Riyaz Mohamed, Kasey M. Belanger, Desmond Moronge, Ahmed A. Elmarakby, Jennifer C. Sullivan

10.1152/ajprenal.00045.2026
View Publication

Mechanism of Impaired Potassium Transport in Pseudohypoaldosteronism (Type II)

Lucilia M A Lessa, Laxiang Wan, Qingshang Yan, Elizabeth Shen, Gerhard Malnic, Gerhard Giebisch, Tong Wang

10.1152/ajprenal.00046.2026
View Publication

Epigenetic Regulation of Nephrogenesis: From Waddington's Landscape to Adult Disease

G.G. Tortelote, S.S. El-Dahr

10.1152/ajprenal.00052.2026
View Publication

Diurnal and sex-specific renal responses to vasopressin receptor 2 agonism and antagonism in mice

Hung Nguyen, Nha V. Huynh, Kelly A. Hyndman

10.1152/ajprenal.00083.2026
View Publication

Arteriovenous fistula creation results in cardiac dysfunction and remodeling in a uremic pig model

Jamie Kane, Prabh Gurbaj Singh, Sreenivasulu Kilari, Gaurav Baranwal, Shreya Roy-Chowdhury, Atanu Naskar, Dan Montonye, Esther Lutgens, Ying Wang, Ahmed S. Negm, Jeremy D. Collins, Timmy Lee, Sanjay Misra

10.1152/ajprenal.00227.2025
View Publication

Frequently asked questions

How long does it take to publish?

Avg. time to first decision: 30 days; avg. time to ahead-of-print publication: 13.2 days; avg. time to final publication: 1.8 months.

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Is a cover letter required?

A cover letter is required for NPRC transfers and should state that the paper is an NPRC submission, describe the changes made, and include the name and manuscript ID of the original journal.

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What are the publication costs?

Open access without APCs in participating journals under the Subscribe to Open program; a flat fee per article is also referenced for institutional participation.

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Research Topics

Ion Transport and Channel Regulation Electrolyte and hormonal disorders Nitric Oxide and Endothelin Effects Renin-Angiotensin System Studies Chronic Kidney Disease and Diabetes Ion channel regulation and function Renal function and acid-base balance Hormonal Regulation and Hypertension Renal and related cancers Acute Kidney Injury Research Renal Diseases and Glomerulopathies Dialysis and Renal Disease Management Birth, Development, and Health Parathyroid Disorders and Treatments Drug Transport and Resistance Mechanisms Neuroendocrine regulation and behavior Receptor Mechanisms and Signaling Eicosanoids and Hypertension Pharmacology Urinary Bladder and Prostate Research Genetic and Kidney Cyst Diseases Biomedical Research and Pathophysiology Pancreatic function and diabetes Magnesium in Health and Disease Adenosine and Purinergic Signaling Neuroscience of respiration and sleep

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