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Blood Advances

Blood Advances is a journal published by the American Society of Hematology featuring current issues, latest articles, collections, and author guidance in hematology.

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Subject Hematology
Impact Factor 7.1
Quartile Q1
Open Access Type Open
ISSN 2473-9529
eISSN 2473-9537
Invitation Only No
Cost Range Publication fees vary by article type.

Submission Instructions

Blood Advances accepts the following article types. Click on an article type to view submission instructions.

Regular Article

Cover Letter A cover letter is required only to disclose any involvement of medical writers or researchers to the Editor-in-Chief. The cover letter must disclose any involvement of medical writers or researchers in writing the article.
Abstract An abstract is required. The abstract must not exceed 250 words. The abstract must be unstructured and written as a continuous narrative.
Manuscript Main text must not exceed 4,000 words, counting only the Introduction, Methods, Results, and Discussion. The manuscript should be ordered as Abstract, Key Points, Introduction, Methods, Results, Discussion, Acknowledgements, Authorship Contributions, Disclosure of Conflicts of Interest, References, Tables, Figure Legends, Figures, and Visual Abstract. The manuscript must include 1 to 2 Key Points of no more than 140 characters each, a Visual Abstract, and a subsection titled “Data Sharing Statement” on the title page that explains database access and provides a contact person for nonpublic data.
References Regular Articles are recommended to include no more than 100 references. References must follow AMA guidelines when no specific style guidance is provided and be formatted according to the Blood Advances Style Guide. References must be listed in numerical order at the end of the article according to first citation in the text, with text citations given as superscript numbers.
Figures & Tables Regular Articles are limited to 7 figures. Figures, tables, figure legends, and the Visual Abstract should appear after the references in the manuscript order, and supplemental data must be submitted with the original manuscript for peer review. The Visual Abstract must be submitted with the initial submission as a PPT file and must be clear, concise, original, minimally text-based, non-tabular, and free of trade names, logos, or trademarked images.
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Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract Review Articles must include an abstract. Abstract must not exceed 250 words. Abstract must be unstructured and written as a continuous narrative.
Manuscript Review Articles must not exceed 4,000 words. Manuscript must be organized as Title Page, Key Points, Abstract, Introduction, Methods, Results, Discussion, Acknowledgments, Authorship Contributions, Conflict of Interest Disclosures, References, Tables, Figure Legends, and Figures. Manuscript must include Key Points and sections for Acknowledgments, Authorship Contributions, and Conflict of Interest Disclosures.
References Review Articles are recommended to include no more than 100 references. References must follow AMA style and the Blood Advances Style Guide. References must be numbered in the order cited, listed in numerical order at the end of the article, and cited in the text with superscript numbers.
Figures & Tables Review Articles are limited to 7 figures. Sequences must be presented as figures rather than tables.
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Systematic Review

Cover Letter A cover letter is required if medical writers or researchers were involved in writing the Systematic Review. The cover letter must disclose any involvement of medical writers or researchers in writing the Systematic Review to the Editor-in-Chief.
Abstract An abstract is required for Systematic Reviews. The abstract must not exceed 250 words. The abstract must be written as a continuous narrative and must not be broken into subheadings.
Manuscript Main text must not exceed 4,000 words, counting only the Introduction, Methods, Results, and Discussion. The manuscript must be organized as Title Page, Key Points, Abstract, Introduction, Methods, Results, Discussion, Acknowledgments, Authorship Contributions, Conflict of Interest Disclosures, References, Tables, Figure Legends, and Figures. Any involvement of medical writers or researchers in writing the Systematic Review must be clearly defined and disclosed in the Authorship and/or Acknowledgments section, and a data sharing statement must be included.
References References must follow AMA guidelines when no specific style guidance is provided and be formatted according to the Blood Advances Style Guide. References must be listed in numerical order at the end of the article according to order of citation in the text, with citations shown as superscript numbers.
Figures & Tables Systematic Reviews are limited to 7 figures. Sequences must be prepared as figures rather than tables.
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Research Letter

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is not required because Research Letters have no abstract.
Manuscript Research Letters must not exceed 1,200 words of text. Research Letters must include a data sharing statement, and a Visual Abstract may be included with the submission.
References Research Letters may include no more than 25 references. References must follow AMA guidelines unless specific style guidance is provided, and they must be formatted according to the Blood Advances Style Guide. References must be listed in numerical order at the end of the article according to order of citation, with superscript numbers used for in-text citations.
Figures & Tables Research Letters may include up to 2 figures or tables.
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Clinical Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract Clinical Guidelines must include an abstract. Abstract must not exceed 250 words. Abstract must be written as an unstructured continuous narrative.
Manuscript Clinical Guidelines have no main text word limit. Manuscript must be organized as Title Page, Key Points, Abstract, Introduction, Methods, Results, Discussion, Acknowledgments, Authorship Contributions, Conflict of Interest Disclosures, References, Tables, Figure Legends, and Figures. Clinical Guidelines must include recommendations based on a high level of evidence and be relevant to patient care, and a Visual Abstract may be included.
References References must follow AMA guidelines when no specific style guidance is provided. References must be listed in numerical order according to first citation in the text, with superscript citation numbers in the manuscript.
Figures & Tables Clinical Guidelines have no figure limit.
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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is not required because Letters To The Editor have no abstract.
Manuscript Manuscript text must not exceed 300 words, excluding the title, references, and author signatures. Letter title must be no more than 60 characters including spaces.
References References must follow AMA guidelines and the Blood Advances Style Guide. References must be listed in numerical order by order of citation and cited in the text with superscript numbers.
Figures & Tables Submission may include up to 1 figure or table.
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Recent Publications

Lust H, Schultz LM, Kwon S, et al. Real-world outcomes for young adult patients receiving CD19 CAR T-cell therapy. Blood Adv. 2025;9(11):2763-2772.

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10.1182/bloodadvances.2026020554
View Publication

Outsmarting NK surveillance: engineering stealth CAR T cells

Ana Karen Nunez Cortes, Rafet Basar

10.1182/bloodadvances.2026020538
View Publication

Lights, camera, occlusion! watch sickle cells in real time

Umut A. Gurkan

10.1182/bloodadvances.2026020303
View Publication

Hockman A, Anuskiewicz S, Brennan E, et al. Efficacy of eculizumab discontinuation in atypical hemolytic uremic syndrome: a systematic review and meta-analysis. Blood Adv . 2025;9(23):6096-6107.

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10.1182/bloodadvances.2026020871
View Publication

Remission with residuals, but no cure

Othman Al-Sawaf

10.1182/bloodadvances.2026020308
View Publication

Frequently asked questions

How long does it take to publish?

Continuously published; new articles are added daily.

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Is a cover letter required?

Cover letter disclosures are required for certain article types when medical writers, researchers, or pharmaceutical or medical device company involvement applies. Advances Viewpoint and unsolicited Review Article submissions are expected to involve presubmission inquiry or prior contact with the Editor-in-Chief.

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What are the publication costs?

Publication fees apply and vary by article type.

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Research Topics

Acute Myeloid Leukemia Research Lymphoma Diagnosis and Treatment CAR-T cell therapy research Hematopoietic Stem Cell Transplantation Chronic Lymphocytic Leukemia Research Platelet Disorders and Treatments Acute Lymphoblastic Leukemia research Hemoglobinopathies and Related Disorders Immune Cell Function and Interaction Myeloproliferative Neoplasms: Diagnosis and Treatment Multiple Myeloma Research and Treatments Chronic Myeloid Leukemia Treatments Blood groups and transfusion Venous Thromboembolism Diagnosis and Management Viral-associated cancers and disorders Blood Coagulation and Thrombosis Mechanisms Iron Metabolism and Disorders T-cell and B-cell Immunology Erythrocyte Function and Pathophysiology Immunodeficiency and Autoimmune Disorders Protein Degradation and Inhibitors CNS Lymphoma Diagnosis and Treatment Hemophilia Treatment and Research Complement system in diseases Virus-based gene therapy research

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