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Cancer Cell International

Cancer Cell International publishes articles on all aspects of cancer cell biology originating from work using laboratory experimentation. The journal focuses on novel cancer studies reporting data from biological experiments performed on cells grown in vitro, in two- or three-dimensional systems, and/or in vivo (animal experiments).

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Subject Oncology
Impact Factor 6
Quartile Q1
Open Access Type Open
eISSN 1475-2867
Invitation Only No
Cost Range APC: £2490.00 GBP / $3290.00 USD / €2790.00 EUR, plus VAT or local taxes where applicable.

Submission Instructions

Cancer Cell International accepts the following article types. Click on an article type to view submission instructions.

Research

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, and confirm the content has not been published or submitted elsewhere.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Methods, Results, and Conclusions, and if reporting a health care intervention on human participants it must also include a Trial registration section with registration number and date and state 'retrospectively registered' if applicable.
Manuscript Manuscript must include a Methods section covering the aim, design and setting of the study, participant characteristics or materials, and all processes, interventions and comparisons, and must include a 'Declarations' section with all required subheadings. Manuscript must include three to ten keywords, a list of abbreviations if abbreviations are used, documentation of any Large Language Model use in the Methods or another suitable section, and under 'Declarations' the subheadings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and optional Authors' information, using 'Not applicable' where a section is not relevant.
References Only published articles, clinical trial registration records, and publicly available abstracts or e-prints/preprints may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web links or URLs must be assigned a reference number and included in the reference list in full with title, URL, and access date.
Figures & Tables Figure titles and legends must be included in the main manuscript rather than the graphic file; tables under one page may be placed within the manuscript and larger tables may be placed at the end of the document; and supplemental data must be cited in the main text. Figures must be numbered in order of first mention, multi-panel figures submitted as single composite files, source data included for any tumour-growth figures, and tables must be numbered in sequence and created with the word processor's table function rather than embedded as figures or spreadsheet files.
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Review

Cover Letter A cover letter is required. The cover letter must explain why the manuscript should be published, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved submission, and confirm the content has not been published or submitted elsewhere.
Abstract An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include Background, Main body of the abstract, and short Conclusion.
Manuscript Reviews should be approximately 3000 words. The manuscript must include Background, Main text, Conclusions, and a Declarations section. Review manuscripts must include three to ten keywords, a list of abbreviations if abbreviations are used, a Declarations section with the specified subheadings including 'Not applicable' where relevant, an Availability of data and materials statement, and documentation of any Large Language Model use in the Methods section or another suitable section if no Methods section is available.
References References must follow Vancouver reference style. Only published, in-press, or publicly available preprint articles, clinical trial registration records, and abstracts may be cited; unpublished abstracts, unpublished data, and personal communications must not appear in the reference list; journal abbreviations must follow Index Medicus/MEDLINE; and web links must be assigned a reference number and included in the reference list in full.
Figures & Tables Tables less than one page may be placed within the manuscript, tables larger than one page may be placed at the end of the document with their intended location indicated in the text, figure titles and legends must appear in the main manuscript, and figures must be uploaded separately in the order first cited. Multi-panel figures must be submitted as a single composite file, tables must be created using the table function rather than embedded as figures or spreadsheet files, and footnotes must not contain figures or tables.
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Comment

Cover Letter A cover letter is required. Cover letter must explain why the manuscript should be published, address any journal policy issues, declare any potential competing interests, and confirm that all authors approved the submission and that the content is not published or under consideration elsewhere.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include Background, Main body of the abstract, and short Conclusion.
Manuscript Manuscript must include a title page, a Main text section with Background and Conclusions sections, and a Declarations section. Manuscript must include 3 to 10 keywords and a Declarations section containing the headings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information, with 'Not applicable' used where a section is not relevant.
References References must follow Vancouver style. References must not be cited in the abstract.
Figures & Tables Tables shorter than one page may be placed in the manuscript near their citation, while tables longer than one page may be placed at the end of the document and figures must be uploaded separately. Figure titles and legends must be included in the manuscript rather than the figure file, and footnotes must not contain figures or tables.
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Recent Publications

Celastrol induces apoptosis of myelodysplastic syndrome cells through a ROS-dependent pro-apoptotic endoplasmic-reticulum stress pathway

Fuxiang Zheng, Wenjun Shao, Li Liu, Chaoying Yang, Dingyu Hu, Xiaoling Su, Xuan Li, Pengfei Cao, Jing Liu, Yunlong Xu, Long Liang, Jun He, Ji Zhang

10.1186/s12935-026-04344-w
View Publication

The anti-leukemic effects of vitamin K4 by modulating the JAK/STAT signaling pathway

Xiuyu Li, Pengcheng Zhu, Shaowen Hu, Qing Huang, Yilin Qin, Huifang Zhu

10.1186/s12935-026-04356-6
View Publication

DNA damage response signature-based prognostic genes for intrahepatic cholangiocarcinoma: a combined analysis of machine learning and biological experiments

Kai Lu, Hanqi Li, Yinying Wu, Xuyuan Dong, Danfeng Dong, Yangwei Fan, Enxiao Li, Liankang Sun, Yu Shi

10.1186/s12935-026-04355-7
View Publication

Machine learning for postoperative complication prediction and early recurrence risk assessment across cancer types: a systematic review and meta-analysis

Wen Chen, Xinliang Liu, Zhenheng Wu, Haifen Tan, Fuqian Yu, Dongmei Wang, Hengyi Gao, Zhigang Chen

10.1186/s12935-025-03912-w
View Publication

ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma

Ping Yan, Yunhai Luo, Dadi Peng, Tong Mou, Dengliang Lei, Shanshan Li, Huarong Yu, Zuotian Huang, Zhongjun Wu

10.1186/s12935-025-03940-6
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 38 days.

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Is a cover letter required?

A cover letter is required. It should explain why the manuscript should be published in Cancer Cell International, address any issues relating to journal policies, declare any potential competing interests, confirm all authors approved the submission, confirm the work has not been published or submitted elsewhere, and identify the special issue name if applicable. Authors may also suggest preferred or non-preferred reviewers in the cover letter.

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What are the publication costs?

An article processing charge applies for each accepted article. The current APC is £2490.00 GBP / $3290.00 USD / €2790.00 EUR, plus VAT or local taxes where applicable.

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Research Topics

Cancer-related molecular mechanisms research MicroRNA in disease regulation RNA modifications and cancer Circular RNAs in diseases Ferroptosis and cancer prognosis Epigenetics and DNA Methylation Cancer Cells and Metastasis Cancer, Hypoxia, and Metabolism RNA Research and Splicing Cancer Immunotherapy and Biomarkers Cancer-related gene regulation Cancer, Lipids, and Metabolism Cancer-related Molecular Pathways Ubiquitin and proteasome pathways Immunotherapy and Immune Responses Cancer Mechanisms and Therapy Cancer Genomics and Diagnostics Immune cells in cancer Autophagy in Disease and Therapy Extracellular vesicles in disease Peptidase Inhibition and Analysis Pancreatic and Hepatic Oncology Research Cancer Research and Treatments Immune Cell Function and Interaction CAR-T cell therapy research

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