CG

Cancer Gene Therapy

Cancer Gene Therapy is a journal focused on gene and cellular therapy for cancer researchers and clinicians.

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Subject Genetics & Heredity, Medicine, Research & Experimental, Oncology
Impact Factor 5
Quartile Q1
Open Access Type Hybrid
ISSN 0929-1903
eISSN 1476-5500
Invitation Only No
Cost Range Open access APC: £2,990 / $4,290 / €3,490, plus VAT or local taxes where applicable.

Submission Instructions

Cancer Gene Therapy accepts the following article types. Click on an article type to view submission instructions.

Article

Cover Letter A cover letter is required. Cover letter must include the corresponding author’s affiliation and contact information, briefly explain the importance of the work and its suitability for the journal readership, confirm originality and exclusive submission, include previous reviewer comments if the manuscript was previously considered by another journal, note competing interests, and bear the corresponding author’s signature.
Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured.
Manuscript Main body text must not exceed 12,000 words, excluding tables, figures, and references. Manuscript must contain a title page, abstract, introduction, materials or subjects and methods, results, discussion including conclusion, references, acknowledgments, author contributions, competing interests, figure legends, tables, and figures. Manuscript must include an Author Contributions section, a funding section, one to four unique subject terms, and disclosure of any large language model use in the Methods section or another suitable section if no Methods section is available.
References References must not exceed 60. References must follow Vancouver format. In-text citations must be numbered consecutively from 1, references must be listed in numerical order of citation, list all authors when there are up to six and the first six followed by et al. when there are more than six, use Index Medicus journal title abbreviations, and provide first and last page numbers.
Figures & Tables A maximum of 7 tables or figures is allowed. Figures must not be embedded in the text and must be uploaded as separate files, and each table must be uploaded separately. Composite figures containing more than three individual figures count as two figures, tables must be editable, and all figures and tables must be labelled sequentially and cited in the text.
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Review Article

Cover Letter A cover letter is required. The cover letter must provide the corresponding author's affiliation, contact information, and signature, briefly explain the importance of the work and its suitability for the journal readership, and confirm that the submission is original, unpublished, and not under consideration elsewhere.
Abstract An abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured.
Manuscript The main body text must not exceed 4,000 words, excluding the abstract, tables, figures, and references. The manuscript must include a title page, abstract, introduction, materials or subjects and methods, results, discussion including conclusion, references, acknowledgments, author contributions, figure legends, tables, and figures. The manuscript must include one to four unique subject terms and document any use of a large language model in the Methods section or another suitable section if no Methods section is available.
References The manuscript may include a maximum of 120 references. References must follow Vancouver format. References must be cited in the text as numbered citations starting at one and listed in numerical order, with all authors named for works with up to six authors and the first six followed by et al. for works with more than six authors.
Figures & Tables The manuscript may include a maximum of 7 tables or figures. Figures must not be embedded within the text and must be uploaded as separate files, and each table must be uploaded as a separate file. Tables must be editable and labelled sequentially with a title or caption, and figures must be labelled sequentially and cited in the text.
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Brief Communication

Cover Letter A cover letter is required. The cover letter must provide the corresponding author's affiliation and contact information, explain the importance of the work and its suitability for the journal readership, confirm originality and exclusive submission, include previous reviewer comments if the manuscript was considered by another journal, note competing interests, and bear the corresponding author's signature.
Abstract An abstract is required. The abstract must be unstructured and no more than 200 words. The abstract must be unstructured.
Manuscript The main body text must not exceed 2 pages, excluding the abstract, tables, figures, and references. The manuscript must include a title page, abstract, introduction, materials or subjects and methods, results, discussion including conclusion, references, acknowledgments, author contributions, competing interests, figure legends, tables, and figures. The manuscript must include an Author Contributions section, a funding section, at least one and no more than four unique subject terms, and documentation of any large language model use in the Methods section or another suitable section if no Methods section is available.
References The submission may include a maximum of 10 references. References must follow the Vancouver format. In-text citations must be numbered consecutively, references must be listed in numerical order, up to six authors must be listed in full and more than six must list the first six followed by et al., medical journal titles must use Index Medicus abbreviations, and each reference must include first and last page numbers.
Figures & Tables The submission may include a maximum of one table or figure. Figures must not be embedded in the text and must be uploaded as separate files, and each table must be uploaded as a separate file. Tables must be editable and clearly labeled sequentially, figures and images must be labeled sequentially and cited in the text, and figure legends must be provided on a separate page after the references.
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Correspondence

Cover Letter A cover letter is required. Cover letter must include the corresponding author's affiliation and contact information, briefly explain the importance of the work and its suitability for the journal readership, confirm originality and exclusive submission, include any previous reviewer comments if the manuscript was previously considered by another journal, note competing interests, and bear the corresponding author's signature.
Abstract Abstract is not required for Correspondence submissions.
Manuscript Manuscript must contain a title page, introduction, materials or subjects and methods, results, discussion including conclusion, references, acknowledgments, author contributions, competing interests, figure legends, tables, and figures. Manuscript must include an Author Contributions section, a funding section, a statement confirming that more than one author directly accessed and verified the reported data, at least one and no more than four unique subject terms, and documentation of any large language model use in the Methods section or another suitable section if no Methods section is available.
References References must follow Vancouver format. References must be cited in the text as numbered citations starting at 1 and listed in numerical order, with all authors listed for up to six authors, the first six followed by et al. for more than six authors, medical journal titles abbreviated according to Index Medicus, and first and last page numbers provided.
Figures & Tables Composite figures containing more than three individual figures count as two figures. Figures must not be embedded within the text and must be uploaded as separate files, and each table must be uploaded as a separate file. Tables must be editable and clearly labelled sequentially with a title or caption, and figures must be labelled sequentially and cited in the text.
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Perspective

Cover Letter A cover letter is required. Cover letter must include the corresponding author's affiliation and contact information, briefly explain the importance of the work and its suitability for the journal readership, confirm originality and exclusive submission, include previous reviewer comments if the manuscript was previously considered elsewhere, note competing interests, and bear the corresponding author's signature.
Abstract Abstract is not required for Perspective submissions.
Manuscript Main body text must not exceed 2,000 words, excluding tables, figures, and references. The manuscript must document any use of a large language model in the Methods section or, if no Methods section is available, in a suitable alternative part of the manuscript, and it must include one to four unique subject terms.
References References are limited to a maximum of 25. References must follow Vancouver format. In-text citations must be numbered consecutively from 1, references must be listed in numerical order of citation, all authors must be listed for references with up to six authors, and references with more than six authors must list the first six authors followed by et al.
Figures & Tables A maximum of 4 tables and/or figures is permitted. Figures must not be embedded in the text and must be uploaded as separate files, and each table must be uploaded as a separate file. Composite figures containing more than three individual figures count as two figures.
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Recent Publications

HOXC11 promotes head and neck squamous cell carcinomas (HNSCC) progression by regulating SPHK1 through the Wnt signaling pathway

Jing Zhang, Qionghui Wu, Jingyuan Liu, Shisheng Li

10.1038/s41417-026-01062-3
View Publication

Glypican-3-targeted therapy in hepatocellular carcinoma: biological insights and therapeutic strategies

Na Li, Shurong Li, Peng Cao, Mengfan Tang, Junfeng Zhang, Wei Zhang, Jinfeng Liu, Chunping Ye, Dan Wu, Xixi Li, Li Dai, Xianglin Zuo

10.1038/s41417-026-01058-z
View Publication

Target therapeutic exploitation of engineered exosome-mediated delivery of ncRNAs in cancer

Fatemeh Chaharlang, Nafiseh Mahdipour, Sana Alizadeh Rami, Parichehr Angouti, Alireza Ahmadi, Mohammad Khalaj-Kondori

10.1038/s41417-026-01059-y
View Publication

Targeting RAB27A-mediated small extracellular vesicle secretion via CRISPR-Cas9 negatively affects proliferation and metastasis in both in vitro and in vivo SCLC models

Onur Tokgün, Kubilay İnci, Aziz Gültekin, Büşra Çelikkaya, Nesrin İrep, Hakan Akça, Pervin Elvan Tokgün

10.1038/s41417-026-01063-2
View Publication

CagA promotes gastric cancer stemness and metastasis via DNMT1-mediated epigenetic silencing of BEX1

Yan Wang, Dajun Chen, Shuai Qian, Fengping Wang, Huibin Weng

10.1038/s41417-026-01057-0
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first editorial decision: 5 median days. Submission to acceptance: 138 median days.

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Is a cover letter required?

A cover letter on institutional letterhead is required at first submission.

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What are the publication costs?

Standard publication is behind a paywall. Gold open access is available with an APC of £2,990 / $4,290 / €3,490, plus VAT or local taxes where applicable.

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Research Topics

Virus-based gene therapy research RNA Interference and Gene Delivery CAR-T cell therapy research Immunotherapy and Immune Responses Cancer Research and Treatments Cancer-related molecular mechanisms research MicroRNA in disease regulation RNA modifications and cancer Viral Infectious Diseases and Gene Expression in Insects Immune Cell Function and Interaction Herpesvirus Infections and Treatments Circular RNAs in diseases Cancer-related Molecular Pathways Cancer, Hypoxia, and Metabolism CRISPR and Genetic Engineering Cell death mechanisms and regulation Epigenetics and DNA Methylation Ubiquitin and proteasome pathways Cancer Immunotherapy and Biomarkers RNA Research and Splicing Advanced biosensing and bioanalysis techniques Animal Virus Infections Studies Cancer Cells and Metastasis interferon and immune responses Cancer-related gene regulation

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