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PLoS Genetics

PLOS Genetics is a genetics journal published by PLOS that features research articles and opinion content and highlights current issues, recently published articles, editorial board updates, and manuscript submission links.

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Subject Genetics & Heredity
Impact Factor 3.7
Quartile Q2
Open Access Type Open
ISSN 1553-7404
eISSN 1553-7404
Invitation Only Yes
Cost Range Publication fees apply; a full list of publication fees, funding initiatives, and fee assistance information is provided by PLOS.

Submission Instructions

PLoS Genetics is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Reviews

Cover Letter A cover letter must be uploaded as a separate file. The cover letter must explain why the manuscript is suitable for publication in PLOS Genetics and why it will inspire the field and drive research forward.
Abstract An abstract is required. Abstract must not exceed 300 words. The abstract must be unstructured. Background, Methodology/Principal Findings, and Conclusions/Significance headings must not be used.
Manuscript Reviews should aim for approximately 3,000 words. Reviews must be organized as Title, Authors, Affiliations, Abstract, Introduction, Main Text, Conclusions, Acknowledgments, and References, with the Main Text broken into subsections as appropriate. Reviews should include an overview of the existing literature in broader context, emphasize future directions, and highlight critical new advances, open questions, and standing controversies or paradoxes.
References Reviews should include a concise list of the most relevant references. References must use Vancouver style. References must be numbered in order of appearance, cited in square brackets, and formatted with the first six authors followed by et al.
Figures & Tables Reviews should include two or three display items, including boxes and conceptual figures. Figure captions, tables, and boxes should be inserted immediately after the first paragraph in which they are cited in the article file.
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Recent Publications

Multi-omics analysis of high-grade serous ovarian cancers reveals heterogeneity and distinct immunological patterns based upon clinico-genomic status

Jing Qian, Rania Bassiouni, Yuxin Jin, Seeta Rajpara, Monica Neuman, Varun U. Khetan, Bodour Salhia, David W. Craig, Joseph W. Carlson, Lynda D. Roman, John D. Carpten

10.1371/journal.pgen.1012355
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The role of gene regulatory evolution in weapon diversification: Insights from comparative genomics, chromatin profiling, and functional analyses of BMP signaling in horned beetles

Phillip L. Davidson, Isabel G. Manley, Armin P. Moczek

10.1371/journal.pgen.1012338
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Meta-analysis of over 8,000 individuals from Hawai‘i and Samoa for genetic associations to cardiometabolic phenotypes

Bryan L. Dinh, Xinran Wang, Xin Sheng, Peggy Wan, Amit Kumar Srivastava, Take Naseri, Satupa‘itea Viali, Lynne Wilkens, Loïc Le Marchand, Christopher Haiman, Daniel E. Weeks, Charleston W. K. Chiang, Jenna C. Carlson

10.1371/journal.pgen.1012342
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Revisiting the impact of synthetic ORF sequences on engineered LINE-1 retrotransposition

Dorothy Chan, Stephanie Workman, Nathan Smits, Alexander L. Carleton, Patricia Gerdes, Jeffrey S. Han, Jef D. Boeke, Geoffrey J. Faulkner, Sandra R. Richardson

10.1371/journal.pgen.1012340
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NLGN3 autism variants have distinct functional impact on synapses and sleep behavior in Drosophila

Rebekah E. Townsley, Jonathan C. Andrews, Saurabh Srivastav, Sharayu V. Jangam, Shabab B. Hannan, Oguz Kanca, Paul C. Marcogliese, Shinya Yamamoto, Michael F. Wangler

10.1371/journal.pgen.1012341
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Frequently asked questions

How long does it take to publish?

Articles are published online as soon as they are ready, with continuous publication occurring as often as daily.

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Is a cover letter required?

A cover letter must be uploaded as a separate file in the online system. It should explain why the manuscript is suitable for publication in PLOS Genetics and why the study will inspire the field and drive research forward. If the Materials and Methods section is placed before the Results or Discussion sections, the cover letter should explain the reason.

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What are the publication costs?

Publication fees apply; PLOS provides publication fees, funding initiatives, and fee assistance information.

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Research Topics

Genomics and Chromatin Dynamics DNA Repair Mechanisms RNA Research and Splicing Genetics, Aging, and Longevity in Model Organisms Chromosomal and Genetic Variations CRISPR and Genetic Engineering Genetic Associations and Epidemiology Epigenetics and DNA Methylation RNA modifications and cancer Plant Molecular Biology Research RNA and protein synthesis mechanisms Fungal and yeast genetics research Genetic Mapping and Diversity in Plants and Animals Genomics and Phylogenetic Studies Bacterial Genetics and Biotechnology Neurobiology and Insect Physiology Research Evolution and Genetic Dynamics Microtubule and mitosis dynamics Mitochondrial Function and Pathology Developmental Biology and Gene Regulation Genetic and phenotypic traits in livestock Genetic diversity and population structure Circadian rhythm and melatonin Photosynthetic Processes and Mechanisms Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

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