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Circulation-genomic And Precision Medicine

Circulation: Genomic and Precision Medicine publishes investigations of clinical genetics and the novel application of precision medicine to drive cardiovascular diagnosis and disease management.

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Impact Factor 5.5
Quartile Q1
Open Access Type Hybrid
ISSN 2574-8300
eISSN 2574-8300
Invitation Only No

Submission Instructions

Circulation-genomic And Precision Medicine accepts the following article types. Click on an article type to view submission instructions.

Human Phenotype-Genotype Association Or Linkage Studies

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must report gene and SNP selection, Hardy-Weinberg statistics or p-values with calculation method, genotyping methods, clearly defined heritable phenotypes with reproducibility data or references for quantitative phenotypes, specifics of the primary models tested, clinically relevant confounders in multivariable models or residuals, plausible candidate genes under the linkage peak, follow-up fine mapping and/or candidate gene genotyping, and replication data from another sample.
References References requirements are not specified.
Figures & Tables Authors are strongly encouraged to limit the number of panels per figure to 6. For initial review, each figure and its corresponding legend should be presented together on its own page within the manuscript PDF. Figure legends must provide a short title, sufficient explanatory detail, definitions of symbols and abbreviations, and disclosure of image acquisition tools, processing software, and any nonlinear adjustments.
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Recent Publications

Long-Term Efficacy and Safety of GLP-1R Agonist and SGLT2 Inhibitor Therapy in the General Population: A Mendelian Randomization Study

Subbaramireddy Remala, Liming Liang, Amil M. Shah, Leo F. Buckley

10.1161/circgen.125.005535
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Biobank-Scale Plasma Proteomics Identifies Novel Biomarkers in Hypertrophic Cardiomyopathy

Jonathan H. Chan, Christopher Grace, Mohsen Mazidi, Robert Clarke, Carolyn Y. Ho, Stefan Neubauer, Christopher M. Kramer, Hugh Watkins, Anuj Goel, William Weintraub, Raymond Kwong, Milind Desai, John DiMarc, Paul Kolm, Patrice Desvigne-Nickens, Nancy Geller, Dong-Yun Kim, John DiMarco, Mark Link, Gary Francis, Barry Greenberg, Milind Desai, Masliza Mahmod, Betty Raman, Daniel Jacoby, Lauren Baldassarre, Jeanette Schulz-Menger, James White, Amedeo Chiribiri, Adam Helms, Lubna Choudhury, Michelle Michels, William Bradlow, Michael Salerno, Michael Salerno, Steven Heitner, Ahmad Masri, Sanjay Prasad, Saidi Mohiddin, Sven Plein, Martin Maron, Christopher Madias, Heiko Mahrholdt, Chiara Bucciarelli-Ducci, Angus Nightingale, Jonathan Weinsaft, Han Kim, Gerry P. McCann, Albert van Rossum, Tjeerd Germans, Eric Williamson, Jeff Geske, Andrew Flett, Dana Dawson, F. Pierre Mongeon, Iacopo Olivotto, Andrew Crean, Anna Woo, Anjali Owens, Lisa Anderson, Sanjay Sharma, Elena Biagini, David Newby, Florian Andre, Colin Berry, Bette Kim, Eric Larose, Theodore Abraham, Allison Hays, Mark Sherrid, Evan Appelbaum, Eli Gelfand, Sherif Nagueh, Ornella Rimoldi, Eleanor Elstein, Matthias Friedrich, Camillo Autore

10.1161/circgen.125.005325
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Scalable System-Wide CYP2C19 Pharmacogenomic Testing Reveals 38% Excess Incidence of Adverse Events in Metabolizers Receiving Inappropriate Prescriptions

Natalie Telis, Douglas Stoller, Christopher N. Chapman, C. Anwar A. Chahal, Daniel P. Judge, Douglas A. Olson, Joseph J. Grzymski, Catherine Hajek, Teresa Kruisselbrink, Nicole L. Washington, Elizabeth T. Cirulli

10.1161/circgen.125.005363
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Rare KDR Variants Define a Distinct Genetic Contribution to Congenital Heart Disease

Feria A. Ladha, Paul Avillach, Alexander R. Opotowsky, Aldweib Nael, Martina Brueckner, Wendy K. Chung, James F. Cnota, Bruce D. Gelb, Matthew Lewis, Cong Liu, Amy E. Roberts, Christine E. Seidman, J.G. Seidman, Martin Tristani-Firouzi, Michael Wagner, Jane W. Newburger, Yuri Kim, Sarah U. Morton

10.1161/circgen.125.005659
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Genome-Wide Association Study of Chronic Venous Insufficiency and Lymphedema in the Million Veteran Program

Gina M. Peloso, Nimish Adhikari, Melissa M. Young, Kelly Cho, Scott Kinlay, Sumitra Muralidhar, Jennifer Moser, Jennifer E. Deen, Philip S. Tsao, Sumitra Muralidhar, J. Michael Gaziano, Elizabeth Hauser, Amy Kilbourne, Michael Matheny, Dave Oslin, Deepak Voora, J. Michael Gaziano, Philip S. Tsao, Jessica V. Brewer, Mary T. Brophy, Lori Churby, Scott L. DuVall, Saiju Pyarajan, Robert Ringer, Luis E. Selva, Shahpoor (Alex) Shayan, Brady Stephens, Stacey B. Whitbourne

10.1161/circgen.125.005442
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Research Topics

Cardiomyopathy and Myosin Studies Genetic Associations and Epidemiology Cardiac electrophysiology and arrhythmias Congenital heart defects research Cardiovascular Effects of Exercise Lipoproteins and Cardiovascular Health Cardiovascular Function and Risk Factors Genomics and Rare Diseases RNA modifications and cancer Viral Infections and Immunology Research Congenital Heart Disease Studies Ion channel regulation and function RNA Research and Splicing Cardiac Arrhythmias and Treatments Cardiac Valve Diseases and Treatments Cardiac pacing and defibrillation studies Cardiac Structural Anomalies and Repair Williams Syndrome Research Health Systems, Economic Evaluations, Quality of Life Connective tissue disorders research Birth, Development, and Health Atherosclerosis and Cardiovascular Diseases Diabetes, Cardiovascular Risks, and Lipoproteins Bioinformatics and Genomic Networks Atrial Fibrillation Management and Outcomes