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Clinical & Experimental Immunology

Clinical and Experimental Immunology is the official journal of the British Society for Immunology, published by Oxford University Press. The journal covers immunology and immune-mediated disease research, with content including original research, reviews, special series, virtual issues, and editorially curated articles.

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Subject Immunology
Impact Factor 3.8
Quartile Q2
Open Access Type Hybrid
ISSN 0009-9104
eISSN 1365-2249
Invitation Only No
Cost Range Hybrid journals offer authors the option of gold open access publishing and authors usually pay an Article Processing Charge (APC) to make research articles available immediately upon publication.

Submission Instructions

Clinical & Experimental Immunology accepts the following article types. Click on an article type to view submission instructions.

Research Article

Cover Letter The cover letter must disclose any use of AI to help generate content or images, write code, process data, or translate.
Abstract required No more than 250 words. unstructured
Manuscript No more than 8,000 words. The main text must use the sections Introduction, Materials & Methods, Results, and Discussion. The manuscript must include a data availability statement, a conflict of interest statement, a funding statement, ethics and consent statements, acknowledgements, a patient consent statement, permission to reproduce material from other sources, and CRediT contributor roles.
References No more than 75 references. Publicly available datasets must be fully referenced with an accession number or unique identifier such as a DOI.
Figures & Tables No more than 10 figures and no more than 10 tables. Tables must be placed at the end of the main text, and figures may be included in the manuscript or submitted separately at first submission. Figures and tables must be numbered and referenced in the text, figure legends must be included in the manuscript file, figures must have alt text in the manuscript, and tables must be editable and not embedded as image files.
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Review

Cover Letter Use of AI to help generate content or images, write code, process data, or for translation must be disclosed in the cover letter.
Abstract required No more than 250 words. unstructured
Manuscript 3,500-5,000 words. The main text must be unstructured, with sub-headings recommended. The manuscript must include no more than 6 keywords and must disclose AI use in the Methods or Acknowledgements section.
References No more than 100 references.
Figures & Tables No more than 10 figures and no more than 10 tables. Figures may be included in the manuscript or submitted as separate files at first submission, and tables must be placed at the end of the main text. Figures and tables must be numbered and referenced in the text, tables must be editable and not embedded as image files, and figures require titles, legends, and alt text in the manuscript file.
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Mini Review

Cover Letter AI use must be disclosed in the cover letter.
Abstract Required. Abstract must not exceed 250 words. Unstructured.
Manuscript Mini Reviews must not exceed 3,000 words. The main text must be unstructured and sub-headings are recommended. The manuscript must include up to 6 keywords, a graphical abstract with a short text summary, and an AI use disclosure in the Methods or Acknowledgements section when applicable.
References Mini Reviews must include no more than 50 references.
Figures & Tables Mini Reviews may include a maximum of 3 figures and 3 tables. Figures may be included in the manuscript or submitted as separate files at first submission. All figures and tables must be numbered and referenced in the text, tables must be editable and placed at the end of the main text, and figures must include titles, legends, and alt text in the manuscript file.
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Short Report

Cover Letter AI use must be disclosed in the cover letter.
Abstract required No more than 250 words.
Manuscript No more than 2,500 words. A graphical abstract is required, and the manuscript must include funding, ethics approval, patient consent, permissions to reproduce material, acknowledgements, and disclosure of AI use where applicable.
References Publicly available datasets must be fully referenced with an accession number or unique identifier such as a DOI, and data citations should include authors, year, title, publisher, and identifier.
Figures & Tables Tables must be placed at the end of the main text, and figures may be included in the manuscript or submitted as separate files at first submission. Tables must be editable and not embedded as image files, figures must have titles and legends in the manuscript file, alt text is required for all images, and graphical abstracts must be submitted as a separate file for peer review.
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Letters To The Editors

Cover Letter A cover letter is required. The cover letter must disclose use of AI to help generate content or images, write code, process data, or for translation, and should mention if authors do not have an institutional or affiliation-linked email address.
Abstract An abstract is required. The abstract must not exceed 250 words. Unstructured.
Manuscript The manuscript must not exceed 1,500 words. The main text must be unstructured. The manuscript must include no more than 6 keywords and must include a graphical abstract with a text summary of no more than three sentences.
References No more than 15 references are allowed. All publicly available datasets must be fully referenced in the reference list with an accession number or unique identifier such as a DOI.
Figures & Tables No more than 2 figures and no more than 2 tables are allowed. At first submission, figures may be included in the manuscript or submitted as separate files. Tables must be numbered and referenced in the text, placed at the end of the main text, editable, and not embedded as image files, and figure titles and legends must be included in the manuscript file.
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Recent Publications

Dysregulated complement activation in COVID-19: The Role of Soluble Complement Inhibitors

Stef van der Meulen, Haiyu Wang, Saskia Nugteren, Frederique Ponchel, Anna H E Roukens, Cilia R Pothast, Mirjam H M Heemskerk, Kyra A Gelderman, Jeroen C J Eikenboom, Bernard M van den Berg, Wendy Stam, Coert Margadant, Simone A Joosten, M S Arbous, S Cannegieter, C M Cobbaert, A van der Does, J J M van Dongen, M C M Feltkamp, A Geluk, J J Goeman, M Giera, T Hankemeier, P S Hiemstra, C H Hokke, J J Janse, S P Jochems, M Kikkert, L Lamont, J Manniën, T H M Ottenhoff, M R del Prado, N Queralt Rosinach, M Roestenberg, M Roos, H H Smits, E J Snijder, F J T Staal, R Tsonaka, A Verhoeven, L G Visser, J J C de Vries, D J van Westerloo, J Wigbers, H J van der Wijk, R C van Wissen, M Wuhrer, M Yazdanbakhsh, M Zlei, Leendert A Trouw

10.1093/cei/uxag064
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Diagnosing primary immunodeficiencies using protein-based screening assays

M Ferro, M Selby, M Davis, K Gilmour

10.1093/cei/uxag062
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Precision targeting and alternative effector cells: Revolutionizing CAR-based therapy for T-cell malignancies

Yingtong Chen, Shuang Gao, Shuozi Liu, Ping Yang, Hongmei Jing

10.1093/cei/uxag060
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Selinexor potentiates NK cell activation against multiple myeloma

Daniel T Harding, Lara V Graham, Laura G Bartlett, Nancy Gudgeon, Jack G Fisher, Christopher J Walker, Trinayan Kashyap, Charlotte E Brookes, Aidan Haslam, Graham McIlroy, Guy Pratt, Ben M Amram, Georgia Francis, Mark S Cragg, Salim I Khakoo, Sarah Dimeloe, Matthew D Blunt

10.1093/cei/uxag059
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Nucleotide-binding oligomerization domain 2-independent colonization by Turicimonas muris induced by high-fat diet protects against dextran sodium sulfate-induced colitis

Hajime Honjo, Tomohiro Watanabe, Yasuo Otsuka, Yasuhiro Masuta, Sho Masaki, Ken Kamata, Kosuke Minaga, Seiichi Omura, Ah-Mee Park, Masatoshi Kudo

10.1093/cei/uxag057
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Frequently asked questions

How long does it take to publish?

2025 median days from submission to first decision: 8 days; 2025 median days from submission to final decision: 8 days.

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Is a cover letter required?

A cover letter is required to explain any authors lacking an institutional or affiliation-linked email address. AI use must also be disclosed in the cover letter.

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What are the publication costs?

Hybrid journals usually require an APC for gold open access publication.

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Research Topics

Immune Cell Function and Interaction T-cell and B-cell Immunology Immune Response and Inflammation Immunotherapy and Immune Responses Monoclonal and Polyclonal Antibodies Research Immunodeficiency and Autoimmune Disorders Systemic Lupus Erythematosus Research Cell Adhesion Molecules Research Diabetes and associated disorders Complement system in diseases HIV Research and Treatment Asthma and respiratory diseases Platelet Disorders and Treatments Vasculitis and related conditions Neutrophil, Myeloperoxidase and Oxidative Mechanisms Cytomegalovirus and herpesvirus research Renal Diseases and Glomerulopathies Reproductive System and Pregnancy Tuberculosis Research and Epidemiology Mycobacterium research and diagnosis Cytokine Signaling Pathways and Interactions IL-33, ST2, and ILC Pathways Blood groups and transfusion Rheumatoid Arthritis Research and Therapies Dermatology and Skin Diseases

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