Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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CP
Clinical Pharmacology & Therapeutics (CPT), the flagship journal of the American Society for Clinical Pharmacology and Therapeutics (ASCPT), is a cross-disciplinary journal in experimental and clinical medicine devoted to publishing advances in the nature, action, efficacy, and evaluation of therapeutics.
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Subject
Pharmacology & Pharmacy
Impact Factor
5.5
Quartile
Q1
Open Access Type
Hybrid
ISSN
0009-9236
eISSN
1532-6535
Invitation Only
No
Cost Range
Open Access APC: $4,630 USD / £3,530 GBP / €3,940 EUR; Society Members receive 17% off the full APC.
Submission Instructions
Clinical Pharmacology & Therapeutics accepts the following article types. Click on an article type to view submission instructions.
Article
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required for Article manuscripts. The abstract must not exceed 250 words. The abstract must be unstructured and must not include headers.
Manuscript
Article manuscripts must not exceed 4,000 words of text only. The manuscript should include Introduction, Materials and Methods, Results, Discussion, Study Highlights, Acknowledgements, Author Contributions statement, References, Tables, Figure Legends, and Supplementary Material titles if included. Study Highlights must appear after the Discussion and stay under 150 words excluding the questions, and an Author Contributions section must appear before the References listing only the roles wrote the manuscript, designed the research, performed the research, analyzed the data, and, if applicable, contributed new reagents/analytical tools.
References
Article manuscripts must not exceed 50 references. References must be listed in citation order, include article titles, and list all authors unless there are more than 6, in which case only the first author should be given followed by et al.
Figures & Tables
Article manuscripts must not exceed 7 figures and tables combined. Tables should be placed after the references in the main text file, and figures must be uploaded separately with figure legends appearing after the references. Tables and figures must be numbered consecutively in order of first citation, and multipart tables are not allowed.
Systematic Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required for Systematic Review and Meta-Analysis manuscripts. The abstract must not exceed 250 words. The abstract must be unstructured and must not include headers.
Manuscript
Systematic Review and Meta-Analysis manuscripts must not exceed 8,000 words of text only. The manuscript should include Introduction, Materials and Methods, Results, Discussion, Study Highlights, Acknowledgements, Author Contributions statement, References, Tables, Figure Legends, and Supplementary Material titles if included. A Study Highlights section under 150 words excluding the questions must appear after the Discussion, and an Author Contributions section listing only the allowed roles must appear before the References.
References
Systematic Review and Meta-Analysis manuscripts must not exceed 100 references. References must be listed in citation order, include article titles, and list all authors unless there are more than 6, in which case only the first author should be followed by et al.
Figures & Tables
Systematic Reviews and Meta-Analyses must not exceed 8 figures and tables combined. Tables must follow the references in the manuscript text, and figures must be uploaded separately as individual files with legends placed after the references. Tables must be numbered consecutively and may not use multipart labels such as Table 1a and 1b, and each table must have a brief title.
Meta-Analysis
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required for this article type. Abstract must not exceed 250 words. Abstract must be unstructured and must not include headers.
Manuscript
Manuscript text must not exceed 8,000 words, excluding the title, references, tables, and figures. Manuscript should include Introduction, Materials and Methods, Results, Discussion, Study Highlights, Acknowledgements, Author Contributions, References, Tables, Figure Legends, and Supplementary Material titles if included. Study Highlights must appear after the Discussion and answer four specified questions in under 250 words, and an Author Contributions section must appear before the References listing only the permitted contribution roles, while any AI use must be credited in the acknowledgements or methods section.
References
References must not exceed 100. References must be numbered in order of citation, include article titles, list all authors unless there are more than 6 in which case only the first author followed by et al. is given, and include only published works or manuscripts in press.
Figures & Tables
The combined total of figures and tables must not exceed 8. Tables must be placed after the references in the main text file, while figures must be uploaded separately and figure legends must appear after the references. Tables must be numbered consecutively and may not use multipart labels such as Table 1a and 1b, and each figure must be submitted as an individual file with multipanel figures combined into a single file.
Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured. Abstract must not include headers.
Manuscript
Manuscript text must not exceed 8,000 words, excluding the title, references, tables, and figures. Text may use headings chosen by the authors, followed by Acknowledgements, References, Tables, Figure Legends, and Supplementary Material titles if included. The main text file must include the title page, unstructured abstract, keywords, body text, references, tables, and figure legends, and any AI use must be credited in the acknowledgements or methods section.
References
References must not exceed 100. References must be listed in citation order and include article titles, with all authors listed unless there are more than 6, in which case only the first author should be given followed by et al.
Figures & Tables
The combined total of figures and tables must not exceed 8. Tables must appear after the references in the manuscript, while figures must be uploaded separately and figure legends must appear after the references in the manuscript text. Tables must be numbered consecutively, may not use multipart labels such as Table 1a and 1b, and each table must have a brief title.
State Of The Art Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
An unstructured abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured and contain no headers.
Manuscript
Manuscript text must not exceed 8,000 words, excluding the title, references, tables, and figures. The main text file must include the title page, unstructured abstract, keywords, body text, references, tables, and figure legends. Keywords must be included, and any use of artificial intelligence must be disclosed in the acknowledgements or methods section.
References
Reference list must not exceed 100 references, including citations appearing in tables and figures. References must be listed in citation order and include all authors up to 6, or the first author followed by et al when there are more than 6, with article titles included.
Figures & Tables
The combined total of figures and tables must not exceed 8. Tables must appear after the references in the manuscript, and figures must be uploaded separately as individual files with figure legends placed after the references. Tables must be numbered consecutively and may not use multipart labels such as Table 1a and 1b.
Brief Report
Cover Letter
Cover Letter requirements are not specified.
Abstract
Brief Reports must include an unstructured abstract. Abstract must not exceed 250 words. Abstract must be unstructured with no headers.
Manuscript
Brief Report manuscripts must not exceed 2,000 words of text only. Manuscript should include Introduction, Materials and Methods, Results, Discussion, Study Highlights, Acknowledgements, Author Contributions, References, Tables, Figure Legends, and Supplementary Material titles if included. Study Highlights must appear after the Discussion and answer four specified questions in under 150 words excluding the questions, and an Author Contributions section must appear before the References listing only the roles wrote the manuscript, designed the research, performed the research, analyzed the data, and contributed new reagents/analytical tools where applicable.
References
Brief Reports must not exceed 25 references. References must be listed in citation order and include all authors up to 6, or the first author followed by et al. if there are more than 6, and article titles are required.
Figures & Tables
Brief Reports must not exceed 2 figures/tables. Tables should be placed after the references in the manuscript, and figures must be uploaded separately with figure legends appearing after the references in the manuscript text. Tables must be numbered consecutively and not use multipart labels, and each figure must be provided as an individual file with multi-panel figures combined into one file.
Mini-Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is required and must be unstructured. Abstract must not exceed 250 words. Abstract must be unstructured and must not include headers.
Manuscript
Manuscript must be 2,000-3,000 words of text only. Main text file must include the title page, an unstructured abstract, keywords, body text, references, tables, and figure legends. Manuscript must include keywords, and any use of artificial intelligence must be credited in the acknowledgements or methods section.
References
References must not exceed 25. References must be listed in the order cited, include article titles, include all authors up to 6 then the first author followed by et al. for more than 6, and include only published works or manuscripts in press in the reference list.
Figures & Tables
Figures and tables must not exceed 4 in total. Tables must be placed after the references in the manuscript, and figures must be uploaded separately with figure legends appearing after the references in the manuscript text. Tables must be numbered consecutively and not labeled as multipart tables, and each figure must be uploaded as an individual file with multiple panels combined into a single file.
Letter To The Editor
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract is not required for Letters To The Editor.
Manuscript
Manuscript text must not exceed 400 words. Letters To The Editor do not require an introduction.
References
Letters To The Editor must not exceed 5 references. References must be listed in the order cited in the text, include article titles, and list all authors up to 6 or only the first author followed by et al. when there are more than 6.
Figures & Tables
Letters To The Editor must not exceed 1 figure or table. Tables should be placed after the references, and figures must be uploaded separately with legends appearing after the references in the manuscript. Tables must be numbered consecutively with brief titles and no multipart tables.
Recent Publications
Machine Learning Model Predicts Clinical Adverse Events of Small Molecule Kinase Inhibitors in Cancer Patients Using On‐/Off‐Target Engagement and Tissue Selectivity
Natalie M. Jusko, Albert Cao, Duxin Sun
10.1002/cpt.70343
View Publication
Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad
10.1002/cpt.70341
View Publication
Bemnifosbuvir: An HCV NS5B Inhibitor With Multiple Modes of Action
Carolin Zitzmann, Ruy M. Ribeiro, Aurélien Marc, Xiao‐Jian Zhou, Alan S. Perelson
10.1002/cpt.70342
View Publication
Cutaneous Adverse Drug Reactions Associated With BRAF and MEK Inhibitors: A Real‐World Analysis of WHO Pharmacovigilance Data
Natalia Sauer, Piotr Giedziun, Jacek Calik, Anna Wiela‐Hojeńska
10.1002/cpt.70326
View Publication
Anifrolumab Dose Regimen Selection for a Phase 3 Trial in Lupus Nephritis
Joachim Almquist, Yen Lin Chia, Raj Tummala, Lynn Bertagnolli, David Jayne, Weifeng Tang, Catharina Lindholm
10.1002/cpt.70307
View Publication
Frequently asked questions
How long does it take to publish?
Median 11 days from submission to first decision, 87 days from submission to acceptance, and 23 days from acceptance to publication.
Reformat to Clinical Pharmacology & Therapeutics using Livewrite PremiumIs a cover letter required?
A cover letter is part of the accepted file formats for submission. If there has been no IRB review of the study, this should be indicated in the cover letter. Video abstract attestations should be provided in a cover letter signed by the corresponding author.
Reformat to Clinical Pharmacology & Therapeutics using Livewrite PremiumWhat are the publication costs?
Open Access APC: $4,630 USD / £3,530 GBP / €3,940 EUR. Society Members receive 17% off the full APC.
Reformat to Clinical Pharmacology & Therapeutics using Livewrite PremiumResearch Topics
Pharmacogenetics and Drug Metabolism
Pharmaceutical studies and practices
Cancer Treatment and Pharmacology
Pharmacological Effects and Toxicity Studies
Drug Transport and Resistance Mechanisms
Antibiotics Pharmacokinetics and Efficacy
Health Systems, Economic Evaluations, Quality of Life
Statistical Methods in Clinical Trials
Analytical Methods in Pharmaceuticals
Chemical synthesis and alkaloids
Anesthesia and Sedative Agents
Cardiac electrophysiology and arrhythmias
Pharmaceutical Economics and Policy
Epilepsy research and treatment
Pharmacology and Obesity Treatment
Computational Drug Discovery Methods
Blood Pressure and Hypertension Studies
Plant-based Medicinal Research
Diverse Scientific and Economic Studies
Inflammatory mediators and NSAID effects
Biosimilars and Bioanalytical Methods
Human auditory perception and evaluation
HIV/AIDS drug development and treatment
Receptor Mechanisms and Signaling
Drug-Induced Hepatotoxicity and Protection