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Comparative Biochemistry And Physiology C-toxicology & Pharmacology

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology publishes papers in comparative, environmental and evolutionary physiology, with a focus on toxicological mechanisms at different levels of organization, including chemical and drug action, biotransformation of xenobiotics, endocrine disruptors, nanoparticles, pharmaceuticals, and natural products chemistry. Studies commonly use molecular approaches together with observations at higher levels of organization to assess how xenobiotics affect physiology.

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Subject Endocrinology & Metabolism, Toxicology
Impact Factor 4.3
Quartile Q2
Open Access Type Hybrid
ISSN 1532-0456
eISSN 1878-1659
Invitation Only No
Cost Range USD 3220 APC for all article types published open access, excluding taxes

Submission Instructions

Comparative Biochemistry And Physiology C-toxicology & Pharmacology accepts the following article types. Click on an article type to view submission instructions.

Research Paper

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Research Papers should typically be 4,000-8,000 words excluding references. Research Papers are normally subdivided into Abstract, Introduction, Materials and Methods, Results, Discussion, and References, with Results and Discussion permitted to be combined. Manuscript must include 1 to 7 English keywords, 3 to 5 highlights submitted as a separate editable file, a graphical abstract submitted separately, and an AI declaration section before the references when AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets and numbered in the order of appearance, with journal names abbreviated according to LTWA.
Figures & Tables Research Papers must include at least 2 figures and/or tables. Figures must be uploaded as separate files, while tables must be provided as editable text. All figures and tables must be cited in the text, numbered in order of appearance, and accompanied by captions.
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Invited Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Invited Reviews should typically be 6,000–10,000 words. Invited Reviews must begin with "Invited Review:" followed by the title, and the manuscript must be divided into clearly defined sections using headings. Manuscript must include 1 to 7 English keywords, required highlights as a separate editable file with 3 to 5 bullet points of no more than 85 characters each, a graphical abstract submitted separately, and an AI declaration section before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance and journal names must be abbreviated according to the LTWA.
Figures & Tables Invited Reviews must include 2 or more figures and/or tables. Figures must be uploaded as separate files and tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively, and provided with captions, and tables must include notes below the table body.
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Graphical Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Graphical Review Articles. Abstract must be no more than 250 words.
Manuscript Body text must be no more than 2,000 words, excluding figure legends. Highlights are required and must be submitted as a separate editable file containing 3 to 5 bullet points, and an abstract of up to 250 words plus 1 to 7 English keywords must be included.
References Graphical Review Articles must include no more than 25 key references. References must be cited in the text using numbers in square brackets and listed in the order they appear in the article.
Figures & Tables Graphical Review Articles must include 3 to 5 color schemes or figures. Figures must be supplied as separate files along with the manuscript, while tables must be submitted as editable text. Each figure must be self-explanatory with sufficient annotations, and figure legends must be concise while adding detail that deepens the figure’s message.
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Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Review Articles should typically be 6,000–10,000 words. Review Articles must begin with "Review:" followed by the title and must not be subdivided into sections. Manuscript must include 1 to 7 English keywords, required highlights of 3 to 5 bullet points submitted as a separate editable file, a required graphical abstract submitted separately, and an AI declaration section before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets and numbered in the order of appearance.
Figures & Tables Review Articles must include 2 to 4 figures or tables. Figures must be uploaded as separate files, while tables must be submitted as editable text. All figures and tables must be cited in the text, numbered in order of appearance, and provided with captions.
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Short Communication

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be unstructured.
Manuscript Manuscript must be less than 3,000 words. Manuscript must begin with "Short Communication:" followed by the title and must not be subdivided into sections. Authors must provide 1 to 7 keywords in English, submit 3 to 5 highlights as a separate editable file, include a graphical abstract, and add an AI declaration statement before the references if AI tools were used in manuscript preparation.
References References must be cited in the text using numbers in square brackets and numbered in the order of appearance.
Figures & Tables Short Communications must have no more than 2 figures and/or tables in total. Figures must be uploaded as separate files, and tables must be submitted as editable text. All figures and tables must be cited in the text, numbered according to order of appearance, and provided with captions.
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Recent Publications

Beyond direct toxicity: Cross-system regulation and the gut-retina axis in pollutant-induced visual dysfunction in fish

Yiqun Wu, Yiwei Liu, Tengzhou Li, Ling Liu, Ping Li, Zhi-Hua Li

10.1016/j.cbpc.2026.110585
View Publication

Neurodevelopmental and behavioral effects of early-life esketamine hydrochloride exposure in zebrafish (Danio rerio)

Shukai Zheng, Taifeng Du, Kusheng Wu, Wenlong Huang

10.1016/j.cbpc.2026.110583
View Publication

Integrated transcriptomic and metabolomic analysis of the toxic effects of PE microplastics on the Kumamoto oyster (Crassostrea sikamea)

Jiangnan Qiu, Xiang Guo, Guiming Fan, Hongqiang Xu, Xuelin Zhao, Jilin Xu

10.1016/j.cbpc.2026.110586
View Publication

Molecular mechanisms underlying metamifop-induced chronic toxicity in Daphnia magna: Insights from metabolic detoxification, oxidative stress, and endocrine disruption

Donglin Yuan, Bangjun Zhang

10.1016/j.cbpc.2026.110584
View Publication

Differential anti-microbial properties between the burying beetle Nicrophorus quadripunctatus and the short sexton beetle Necrodes littoralis

Jong Hyeok Lee, Woo-Jin Kim, Yue Gao, Neung-Ho Ahn, Won-Jae Chi, Si Hyeock Lee, Kyungjae Andrew Yoon

10.1016/j.cbpc.2026.110582
View Publication

Frequently asked questions

How long does it take to publish?

3 days submission to first decision; 47 days submission to decision after review; 99 days submission to acceptance; 3 days acceptance to online publication

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What are the publication costs?

Open access APC: USD 3220 excluding taxes for all article types. Subscription publishing has no open access publication fee.

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Research Topics

Environmental Toxicology and Ecotoxicology Aquaculture Nutrition and Growth Physiological and biochemical adaptations Reproductive biology and impacts on aquatic species Aquaculture disease management and microbiota Pharmaceutical and Antibiotic Environmental Impacts Human auditory perception and evaluation Diverse Scientific and Economic Studies Educational Robotics and Engineering Heavy Metal Exposure and Toxicity Effects and risks of endocrine disrupting chemicals Trace Elements in Health Toxic Organic Pollutants Impact Mercury impact and mitigation studies Zebrafish Biomedical Research Applications Marine Biology and Environmental Chemistry Microplastics and Plastic Pollution Insect and Pesticide Research Nanoparticles: synthesis and applications Pesticide Exposure and Toxicity Fish Ecology and Management Studies Venomous Animal Envenomation and Studies Neurobiology and Insect Physiology Research Invertebrate Immune Response Mechanisms Heavy metals in environment

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