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The CRISPR Journal

The CRISPR Journal is a peer-reviewed journal dedicated to the science and applications of gene editing, publishing international original research along with review articles, perspectives, profiles, and commentary.

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Subject Genetics & Heredity
Impact Factor 4
Quartile Q1
Open Access Type Hybrid
ISSN 2573-1599
eISSN 2573-1602
Invitation Only No
Cost Range Article processing charges apply for hybrid open access, and institutional agreements, prepaid accounts, or discounts may help cover APCs.

Submission Instructions

The CRISPR Journal accepts the following article types. Click on an article type to view submission instructions.

Original Research Articles

Cover Letter Cover letter is required only if third-party writing or editing assistance was used or if the submission was made on behalf of the authors by someone not listed as an author. Cover letter must disclose any third-party writing or editing assistance and state if the submission was made on behalf of the authors by someone not listed as an author.
Abstract Original Research Articles must include an abstract. Abstract must be unstructured and must not exceed 150 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 5,000 words, excluding the abstract, disclosure statements, author contribution statements, funding information, acknowledgments, tables, figure legends, and references. Manuscript must be organized as Introduction, Materials and Methods, Results, Discussion, and Conclusions. Manuscript must include at least 4 keywords after the abstract, an Author Contributions section after the Acknowledgements, and a Statements and Declarations section at the end with each required subheading included even when marked 'Not applicable'.
References Original Research Articles may include a maximum of 100 references. References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.
Figures & Tables Original Research Articles may include a maximum total of 10 figures and tables. Figures, charts, and tables created in Word must be included in the main text, while figures and other files created outside Word must be submitted separately with a placeholder note in the text. Figures must be numbered consecutively in the order cited, and tables must be labeled as tables with a number and title and be editable within Word rather than included as images.
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Review Articles

Cover Letter Cover letter is required only if writing or editing assistance from a third party must be disclosed or if the submission is made on behalf of the authors by someone not listed as an author. Cover letter must disclose any third-party writing or editing assistance and state if the submission was made on behalf of the authors by someone not listed as an author.
Abstract An unstructured abstract is required. Abstract must not exceed 150 words. Abstract must be unstructured.
Manuscript Manuscript must not exceed 5,000 words. Manuscript must be organized as Introduction, Materials and Methods, Results, Discussion, and Conclusions. Manuscript must include at least 4 keywords after the abstract, an Author Contributions heading after the Acknowledgements section, a Statements and Declarations section at the end of the article, and any AI use disclosure in the Acknowledgements or Methodology section if applicable.
References Review Articles may include a maximum of 150 references. References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in both places.
Figures & Tables Review Articles may include a maximum combined total of 10 figures and tables. Figures, charts, and tables created in Word must be included in the main text, while figures and other files created outside Word must be uploaded separately with a placeholder note in the text for separately submitted figures. Figures must be numbered consecutively in the order cited, and tables must be labeled as tables with a number and title and include a header row and/or column.
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Correspondence

Cover Letter Cover letter must disclose any third-party writing or editing assistance and state if the submission was made on behalf of the authors by someone not listed as an author.
Abstract Abstract requirements are not specified.
Manuscript Correspondence must not exceed 800 words. Include a minimum of 4 keywords after the abstract, an Author Contributions heading after the Acknowledgements section, and a Statements and Declarations section with all required subheadings, including 'Not applicable' where relevant.
References Correspondence may include a maximum of 10 references. References must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and each reference list entry must have a corresponding in-text citation.
Figures & Tables Correspondence may include 1 figure or 1 table. Figures, charts, and tables created in Word must be included in the main text, while figures created outside Word must be submitted separately with a placeholder note in the text. Figures must be numbered consecutively in the order they appear in the text, and tables must include a number and title.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must not exceed 500 words. Article must include a section headed 'Statements and Declarations' at the end of the article, and a minimum of 4 keywords after the abstract.
References References should not exceed 5. References and citations must follow Sage Vancouver style. Every in-text citation must have a corresponding reference list entry and vice versa, with identical spelling and year in corresponding citations.
Figures & Tables Article may include 1 figure or 1 table. Figures, charts, and tables created in Word must be included in the main text, while figures and other files created outside Word must be submitted separately with a placeholder note in the text. Figures must be numbered consecutively in the order cited, and tables must include a number and title.
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Recent Publications

Hidden Outcomes of CRISPR-Cas9 Genome Editing Revealed by Targeted Sequencing in Isogenic Human iPSC Clones

Maria Tubalova, Galina Koksharova, Silvia Souza da Costa, Ana Cristina Victorino Krepischi, Veniamin Fishman, Maria Gridina

10.1177/25731599261492640
View Publication

PARP1 Constrains Insertional Prime Editing in a Context-Dependent Manner

Iryna Vykhlyantseva, Haribaskar Ramachandran, David Alejandro Morales-Juarez, Andrea Rossi, Jacob Corn, Zacharias Kontarakis

10.1177/25731599261491273
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Addressing the Blind Spots of Deaminase Base Editors with CRISPR-Cas Glycosylase-Based Editors

Jian Zhou

10.1177/25731599261475668
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Comparison of CRISPR-Cas-Based Knockdown of Endogenous mRNA in Sensory Neurons

Andrea Meulenberg, Macarena Pavez, Emma K. Gowing, David Mayo-Muñoz, Nils Birkholz, Graceallah Suhono, Peter C. Fineran, Robert D. Fagerlund, Laura F. Gumy

10.1177/25731599261489437
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Genomic Benchmarking Reveals Reduced and Context-Dependent Transferability of AI-Engineered Bxb1 Recombinases for Large-Fragment Genome Writing

Yi-Dan Sun, Li-Jun Song, Bin Liu, Chong-Yan Cheng, Li-Ming Zhang, Jian-Ping Zhang, Xiao-Bing Zhang

10.1177/25731599261470587
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Frequently asked questions

How long does it take to publish?

OnlineFirst publication enables final articles to be published online immediately after finalization, without waiting for assignment to a future issue.

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Is a cover letter required?

A covering letter is required when third-party writing or editing assistance is involved and when a submission is made on behalf of the authors by a non-author.

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What are the publication costs?

Article processing charges apply for hybrid open access, and institutional agreements, prepaid accounts, or discounts may help cover APCs.

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Research Topics

CRISPR and Genetic Engineering RNA and protein synthesis mechanisms Advanced biosensing and bioanalysis techniques Innovation and Socioeconomic Development Insect symbiosis and bacterial influences Pluripotent Stem Cells Research Biomedical Ethics and Regulation Virus-based gene therapy research RNA regulation and disease Animal Genetics and Reproduction Genetics, Aging, and Longevity in Model Organisms Genetically Modified Organisms Research Mosquito-borne diseases and control RNA Interference and Gene Delivery CAR-T cell therapy research Chromosomal and Genetic Variations Biotechnology and Related Fields Plant Virus Research Studies Intellectual Property and Patents Bacteriophages and microbial interactions Insect Resistance and Genetics Viral Infections and Immunology Research Viral Infectious Diseases and Gene Expression in Insects Evolution and Genetic Dynamics Neuroethics, Human Enhancement, Biomedical Innovations

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