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Current Gene Therapy

Current Gene Therapy is a journal in gene therapy with ISSN 1566-5232 (print) and 1875-5631 (online). It has an Impact Factor of 3.3, is indexed in Scopus, SCI Expanded, and MEDLINE/PubMed, and publishes Volume 26 in 2026. The journal offers online manuscript submission and includes both subscription content and open access articles.

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Subject Genetics & Heredity
Impact Factor 3.3
Quartile Q2
Open Access Type Hybrid
ISSN 1566-5232
eISSN 1875-5631
Invitation Only No
Cost Range Publication charges are US $690 for research articles, US $190 for short communications/letters, and US $290 for review articles. Optional Gold Open Access costs US $3633 per article for general submissions and US $1900 for thematic issues. Optional Quick Track costs US $4845 per article.

Submission Instructions

Current Gene Therapy accepts the following article types. Click on an article type to view submission instructions.

Review Articles

Cover Letter A signed copyright letter must be submitted with the manuscript.
Abstract A structured abstract is required for Review Articles. Abstract must not exceed 250 words. Abstract must be structured.
Manuscript Review Articles must be 6000-10000 words, excluding figures, structures, photographs, schemes, and tables. Review Articles must be divided into a title page, abstract, and main text, followed by List of Abbreviations, Conflict of Interest, Acknowledgements, and References. Review Articles must include a Graphical Abstract, Keywords, Conclusion, List of Abbreviations, Consent for Publication, Availability of Data and Materials, Funding, Conflict of Interest, Acknowledgements, References, Appendices, Figures/Illustrations, Chemical Structures, Tables, and Supportive/Supplementary Material.
References Review Articles must contain 100 or more references. References should preferably be in ACS or Vancouver style. Reference numbers must be given in square brackets in the text.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and tables must be embedded in the text, although figures and illustrations must also be provided as separate electronic files for online submission. Figures must be numbered consecutively in the order of appearance, and tables must be numbered in Arabic numerals sequentially in order of citation.
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Mini-Reviews

Cover Letter A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors. The corresponding author must confirm approval from all listed authors for the submission and publication of all versions of the manuscript, and all co-authors must sign a declaration accepting full responsibility for the manuscript content.
Abstract An abstract is required. Abstract must not exceed 250 words. The abstract should be structured. The abstract should include the study purpose, participant details, measurements, methods, main findings, and conclusion.
Manuscript Mini-Reviews must be 3000-6000 words, excluding figures, structures, photographs, schemes, and tables. The main text must begin on a separate page with numbered section headings and numbered italicized sub-section headings. The manuscript must include 6 to 8 keywords, a conflict of interest statement, an Authors' Contribution paragraph, a CRediT author statement, and disclosure of any significant AI tool use.
References Mini-Reviews must contain 75 or more references. References must be submitted preferably in ACS or Vancouver style. References must be complete and fully formatted before submission, cited in the text with numbers in square brackets, and must not include abstracts, unpublished data, or personal communications.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and tables must be embedded in the text at their appropriate placement, while figure files must also be provided separately for online submission. Figures and tables must be numbered consecutively in the order of appearance and cited in the text, each figure must contain a single illustration, and each table must include a self-explanatory title or caption.
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Systematic Reviews

Cover Letter A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors. The corresponding author must have approval from all listed authors for the submission and publication of all versions of the manuscript.
Abstract A structured abstract is required for Systematic Reviews. Abstract must not exceed 250 words. The abstract must be structured. The structured abstract must include Introduction/Objective, Methods, Results, Discussion, and Conclusion.
Manuscript Systematic Reviews must be 4000-6000 words, excluding figures, structures, photographs, schemes, and tables. Systematic Reviews are required to address the methods used for selecting, locating, extracting, and synthesizing data. Registered systematic reviews must include the registration number as the last line of the abstract, and the manuscript must include an Authors' Contribution paragraph, a CRediT author statement, conflict of interest and funding declarations, and disclosure of any significant AI tool use.
References Systematic Reviews must contain 100 or more references. References must be submitted preferably in ACS or Vancouver style. Reference numbers must be given in square brackets in the text, and abstracts, unpublished data, and personal communications must not be included in the references section.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and tables must be embedded in the text file at their appropriate placement, although figures and illustrations must also be provided as separate files for online submission. Figures must be numbered consecutively in the order of appearance and each table must be numbered in Arabic numerals sequentially in order of citation.
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Meta-Analyses

Cover Letter A signed copyright letter must be submitted by the corresponding author on behalf of all co-authors. The corresponding author must confirm approval from all listed authors for submission and publication of all versions of the manuscript in the copyright letter.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. The structured abstract must include Introduction/Objective, Methods, Results, Discussion, and Conclusion.
Manuscript The manuscript must include 6 to 8 keywords, a conflict of interest statement, an Authors' Contribution paragraph, a CRediT author statement, and disclosure of any significant AI tool use.
References References must be submitted preferably in ACS or Vancouver style. References must be cited in the text using square-bracketed numbers and the bibliography must be fully formatted before submission.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and chemical structures must be uploaded as separate files, while figures and tables must also be embedded in the manuscript at their appropriate placement. Figures must be numbered consecutively and each figure must contain a single illustration, while tables must be numbered sequentially and include a self-explanatory title or caption.
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Research Articles

Cover Letter A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors. The corresponding author must include confirmation in the copyright letter that all listed authors approved the submission and publication of all versions of the manuscript.
Abstract A structured abstract is required for Research Articles. The abstract must not exceed 250 words. The abstract must be structured. The structured abstract must include the subheadings Introduction/Objective, Methods, Results, Discussion, and Conclusion.
Manuscript Research Articles must be 4000-6000 words excluding figures, structures, photographs, schemes, and tables. Research Articles must begin with the title page and abstract followed by the main text and be structured into Introduction, Materials and Methods, Results, Discussion, and Conclusion. Research Articles must include a Graphical Abstract, 6 to 8 keywords, a List of Abbreviations, Funding, Conflict of Interest, Acknowledgements, References, Appendices, Figures/Illustrations, Chemical Structures, Tables, Supportive/Supplementary Material, and disclosure of any significant AI tool use in the manuscript.
References Research Articles must contain 75 or more references. References must be submitted preferably in ACS or Vancouver style. References must be numbered in square brackets in the text and listed as complete and fully formatted entries, with abstracts, unpublished data, and personal communications excluded from the reference list.
Figures & Tables There is no restriction on the number of figures or tables that can be included online with each article. Figures and tables must be embedded in the text at their appropriate placement, although figures and illustrations must also be provided as separate files for online submission. Figures and tables must be numbered consecutively in the order of citation, each figure must include only a single illustration with legends or captions provided, and each table must include a self-explanatory title or caption.
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Randomized Drug Clinical Trial Studies

Cover Letter A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors.
Abstract Abstract must not exceed 250 words. Abstract should be structured.
Manuscript Manuscript must be 4000-6000 words excluding figures, structures, photographs, schemes, and tables. Manuscript must clearly state the objective or hypothesis, design and methods, essential features of interventions, main outcome measures, main results, a comment section addressing the published literature and study limitations, and the conclusions, and it must include a “Randomization and Masking” section within the Methods section. Manuscript must include 6 to 8 keywords and disclose any significant use of AI tools, including naming the tool used for image or graphical production or for data collection and analysis in the Materials and Methods or similar section.
References References must number 50 or more. References must be submitted preferably in ACS or Vancouver style. Reference numbers must be cited in square brackets in the text, and abstracts, unpublished data, and personal communications must not be included in the reference list.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and tables must be embedded in the text, although figures and illustrations must also be provided as separate files for online submission. Figures must be numbered consecutively and cited in sequence in the text, and each table must include a self-explanatory title or caption and be numbered sequentially in Arabic numerals.
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Short Communications

Cover Letter A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors. The copyright letter must include approval from all listed authors for submission and publication, and all co-authors must sign a declaration accepting full responsibility for the manuscript content regardless of any AI use.
Abstract An abstract is required. Abstract must not exceed 250 words. The abstract should be structured. The structured abstract should include the study purpose, participant details, measurements, methods, main findings, and conclusion.
Manuscript Short Communications must be 2000-3000 words excluding figures, structures, photographs, schemes, and tables. The main text must begin on a separate page and use sequentially numbered section and subsection headings. The manuscript must include 6 to 8 keywords, a conflict of interest statement, an Authors' Contribution paragraph, a CRediT author statement, and disclosure of any significant AI tool use.
References Short Communications must contain 25 or more references. References must be submitted preferably in ACS or Vancouver style. References must be complete and fully formatted before submission, numbered in square brackets in the text, and must not include abstracts, unpublished data, or personal communications.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and tables must be embedded in the text at their appropriate placement, although figures and illustrations must also be provided as separate electronic files for online submission. Figures and tables must be numbered consecutively in order of appearance and citation, each figure must contain only a single illustration, and each table must include a self-explanatory title or caption.
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Letters

Cover Letter A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors.
Abstract An abstract is required for Letters. Abstract must not exceed 250 words. Abstract must be structured.
Manuscript Letters must be 3000-4000 words, excluding figures, structures, photographs, schemes, and tables. Letters must begin with the title page and abstract followed by sections for Introduction, Materials and Methods, Results, Discussion, Conclusion, Acknowledgements, and References. Manuscripts must include 6 to 8 keywords and disclose any significant use of AI tools in the work.
References Letters must contain 40 or more references. References must be submitted preferably in ACS or Vancouver style. Reference numbers must be cited in square brackets in the text and the bibliography must be fully formatted before submission.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included with each article online. Figures and tables must be embedded in the text, and figures and illustrations must also be provided as separate files for online submission. Figures and tables must be numbered consecutively in the order of appearance and each must be cited in the text.
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Case Reports

Cover Letter A signed copyright letter must be submitted with the manuscript.
Abstract Abstract must not exceed 250 words. Abstract should be structured.
Manuscript Case Reports must be 1500–2500 words excluding figures, structures, photographs, schemes, and tables. Authors must provide 6 to 8 keywords, include a conflict of interest statement, an Authors' Contribution paragraph, a CRediT author statement, and disclose any significant use of AI tools in the work.
References Case Reports must include 40 or more references. References should preferably follow ACS or Vancouver style. References must be complete and accurate, fully formatted before submission, and cited in the text with square-bracketed numbers.
Figures & Tables There is no restriction on the number of figures, tables, or additional files that can be included online. Figures and tables must be embedded in the text at their appropriate placement, although figure files must also be provided separately for online submission. Figures must be numbered consecutively with legends and captions, and tables must be numbered sequentially and include a self-explanatory title or caption.
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Recent Publications

Efficacy and Safety of Immune Checkpoint Inhibitors for Recurrent or Metastatic Cervical Cancer: A Systematic Review and Meta-Analysis

Yuanyuan Li, Songyi Wang, Yirui Mai, Zhixi You, Yu Wang, Jiake Wang, Ye Lei

10.2174/0115665232459323260803060556
View Publication

Targeting FUNDC1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma by Suppressing Mitochondrial Function

Weinan Yao, Dong Guo, Xueyuan Zhang, Xingyu Du, Wenbin Shen, Shuchai Zhu

10.2174/0115665232502208260729114754
View Publication

The TRH-TRHR Axis Acts as a Metabolic Checkpoint for Ammonia Tolerance in AML: Therapeutic Targeting via Imiquimod and Itraconazole

Yan Wang, Xinhui Qiu, Weiwei Liu, Zhixiang Lei, Zheying Wang, Xiaoyu Zhang, Hongxing Wang, Hongchun Wang

10.2174/0115665232513251260729055334
View Publication

ZBTB33/RBM15 Axis Upregulates MACC1 to Promote the Malignant Progression of Colorectal Cancer

Lichun Wang, Bin Guo, Xueping Jiao, Quanmao Zhang, Sheng Gao

10.2174/0115665232510920260717033443
View Publication

Integration of Single-Cell Transcriptomics and Network-Based Machine Learning Identifies Bone Marrow Mesenchymal Stem Cell-Associated Candidate Biomarkers and Exploratory Immune Correlates in Osteoarthritis

Hanyu Wang, Zhikang Chen, Shikai Chen, Honglin Pi, Qianqian Liang, Li Wang

10.2174/0115665232502221260728112834
View Publication

Frequently asked questions

How long does it take to publish?

Quick Track allows online publication within 2 weeks of receipt of the final approved galley proofs and 10 weeks from first receipt of the manuscript to online publication, subject to acceptance and author revisions within one week. Revised papers are usually requested within 15 days, with revision time varying from 1 to 4 weeks. Proofs should be returned within 48 hours.

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Is a cover letter required?

A signed copyright letter must be submitted with the manuscript by the corresponding author on behalf of all co-authors.

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What are the publication costs?

Publication charges are US $690 for research articles, US $190 for short communications/letters, and US $290 for review articles. Optional Gold Open Access costs US $3633 per article for general submissions and US $1900 for thematic issues.

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Research Topics

Virus-based gene therapy research RNA Interference and Gene Delivery CRISPR and Genetic Engineering Viral Infectious Diseases and Gene Expression in Insects Cancer Research and Treatments CAR-T cell therapy research Animal Genetics and Reproduction Pluripotent Stem Cells Research MicroRNA in disease regulation Advanced biosensing and bioanalysis techniques Diverse Scientific and Economic Studies Mesenchymal stem cell research Retinal Development and Disorders Herpesvirus Infections and Treatments Biomedical Ethics and Regulation Viral gastroenteritis research and epidemiology Human auditory perception and evaluation Immunotherapy and Immune Responses Muscle Physiology and Disorders Ferroptosis and cancer prognosis Microbial Inactivation Methods Circular RNAs in diseases Nerve injury and regeneration Cancer-related molecular mechanisms research Bacteriophages and microbial interactions

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