Cy

Cytokine

Cytokine is an official journal of the International Cytokine & Interferon Society. It publishes studies on the molecular biology, signal transduction, genetics, biochemistry, immunology, genome-wide association, pathobiology, diagnostic, clinical, and therapeutic applications of cytokines, cytotoxins, interferons, chemokines, adipokines, matrikines, hematopoietic factors, and growth factors, including related signaling molecules and biological response modifiers involved in inflammation, immunity, host defenses, and immune responses.

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Subject Immunology
Impact Factor 3.7
Quartile Q2
Open Access Type Hybrid
ISSN 1043-4666
eISSN 1096-0023
Invitation Only No
Cost Range Article Publishing Charge (APC): USD 3300 for all articles published open access, excluding taxes.

Submission Instructions

Cytokine accepts the following article types. Click on an article type to view submission instructions.

Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Unstructured.
Manuscript Subsections must be numbered, and section numbering must be used for cross-referencing. Article highlights must be submitted as a separate editable file with 3 to 5 bullet points, keywords must be provided, and a generative AI declaration must be added before the references if AI tools were used.
References Numbered citations in square brackets. References must be numbered in order of appearance, all cited references must appear in the list and vice versa, journal names must be abbreviated using LTWA, and web, data, and preprint references have specific required elements.
Figures & Tables Tables may be placed next to the relevant text or on separate pages at the end of the article, and figures and other artwork must be supplied as separate files along with the manuscript. Tables must be editable text and cited in the manuscript; all images must be cited and numbered in order, each artwork must have a caption, and graphical abstracts must be submitted separately as an image file.
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Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Unstructured.
Manuscript Sections and subsections must be numbered, and the introduction must clearly state the objectives of the work. Article highlights must be submitted as a separate editable file with 3 to 5 bullet points, keywords must be provided in English, and a generative AI declaration must be added in a new section before the references if AI tools were used.
References Numbered citation style. References must be cited in text by numbers in square brackets, numbered in the order they appear, and journal names must be abbreviated according to LTWA.
Figures & Tables Tables must be submitted as editable text and placed next to the relevant text or on separate pages at the end of the article, while figures and other artwork must be supplied as separate files. All tables and images must be cited and numbered in order, captions are required, and each image must be submitted as a separate file with minimal text.
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Short Communications

Cover Letter A cover letter is required. The cover letter must include the word count.
Abstract An abstract is required. The abstract must not exceed 250 words. Unstructured.
Manuscript The manuscript must not exceed 2000 words. Results and Discussion may be combined. Article highlights are required, and the manuscript must include a generative AI declaration section before the references if AI tools were used.
References No more than 15 references. Numbered citations. References must be cited in the text by numbers in square brackets and numbered in the order they appear in the article.
Figures & Tables No more than 2 figures and/or tables. Figures and tables must be uploaded separately, and tables may be placed next to the relevant text or on separate pages at the end of the article. Tables must be editable text and all figures and tables must be cited in the manuscript.
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Cytokine Stimulus

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Unstructured.
Manuscript Cytokine Stimulus manuscripts must not exceed 1500 words. Article highlights are required at submission, and if generative AI tools were used, a declaration statement must be added in a new section before the references list.
References References must be numbered in the order they appear in the article and cited in the text by numbers in square brackets.
Figures & Tables Tables may be placed next to the relevant text or on separate pages at the end of the article, and figures and other artwork must be supplied as separate files. Tables must be editable text and numbered consecutively, figures and tables must be cited in the manuscript text, and artwork must have captions.
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Recent Publications

Maternal and early-life longitudinal cytokine profiles in a South African birth cohort: the impact of HIV

Tusekile S. Kangwa, Catherine J. Wedderburn, Jenna F. Annandale, Kirsten A. Donald, Francesca Little, Heather J. Zar, Dan J. Stein, Petrus J.W. Naudé

10.1016/j.cyto.2026.157182
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Development of a cholera toxin B subunit-adjuvanted Helicobacter pylori multi-epitope vaccine and evaluation of its immunization effect in mice

Ke Liang, Shuang Wu, Sihang Dong, Baiqing Li, Zhongqing Qian, Xiaojing Wang, Hongtao Wang, Tao Xu

10.1016/j.cyto.2026.157191
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Adipose tissue macrophages in metabolic inflammation and disease: Insights from single-cell and multi-omics studies

Qining Huang, Jingwen Tang, Xiaozheng Shu, Zhaoliang Su, Yu Tian

10.1016/j.cyto.2026.157192
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Th1/Th2 cytokine imbalance with novel IL-17F elevation in Iraqi transfusion-dependent beta-thalassemia: a dual-platform diagnostic study

Suzan Sabbar Mutlag, Ghaith A. Al-Tameemi, Mohammed Abdul-Mounther Othman

10.1016/j.cyto.2026.157189
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The significance of vascular endothelial growth factor and systemic inflammatory reaction in bladder cancer patients

Zofia Strojny, Dominika Kanikowska, Alina Kanikowska, Zofia Tomczak, Wiesław Sikora, Maki Sato, Marcin Strojny, Joanna Żuraszek-Szymańska, Tomasz Deja, Andrzej Bręborowicz, Katarzyna Korybalska

10.1016/j.cyto.2026.157190
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Frequently asked questions

How long does it take to publish?

Proof corrections are requested within two days. The publication date can be delayed on request, but publication after the delay period is not guaranteed.

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Is a cover letter required?

A cover letter is required for Short Communications and must include the word count.

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What are the publication costs?

Open access publication requires an APC of USD 3300 for all articles, excluding taxes. Subscription publication has no open access publication fee.

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Research Topics

Immune Response and Inflammation Cytokine Signaling Pathways and Interactions Immune Cell Function and Interaction interferon and immune responses Chemokine receptors and signaling T-cell and B-cell Immunology Immunotherapy and Immune Responses Adipokines, Inflammation, and Metabolic Diseases IL-33, ST2, and ILC Pathways Psoriasis: Treatment and Pathogenesis Cell Adhesion Molecules Research NF-κB Signaling Pathways Immune cells in cancer Inflammasome and immune disorders Monoclonal and Polyclonal Antibodies Research Diverse Scientific and Economic Studies Human auditory perception and evaluation Asthma and respiratory diseases Educational Robotics and Engineering Reproductive System and Pregnancy Atherosclerosis and Cardiovascular Diseases Systemic Lupus Erythematosus Research Rheumatoid Arthritis Research and Therapies Dermatology and Skin Diseases Immunodeficiency and Autoimmune Disorders

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