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Drug Discovery Today

Drug Discovery Today delivers informed and highly current reviews for the discovery community. The journal covers scientific developments in drug discovery technologies as well as management, commercial, and regulatory issues affecting R&D, including novel therapeutic strategies, high-throughput screening, therapeutic targets, combinatorial chemistry, drug delivery, ADME/Tox, genomics, proteomics, automation, virtual chemistry, informatics, business strategy, and clinical trials.

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Impact Factor 7.5
Quartile Q1
Open Access Type Hybrid
ISSN 1359-6446
eISSN 1878-5832
Invitation Only Yes
Cost Range USD 4480 APC for open access articles; no open access publication fee for subscription articles.

Submission Instructions

Drug Discovery Today is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Short Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for Short Reviews. The abstract must be 100 words.
Manuscript Short Reviews must be 3500 words. The manuscript must include a 25–30-word teaser, 4 or 5 highlight statements of no more than 85 characters including spaces, 1 to 7 keywords in English, and a generative AI declaration section before the references if AI was used in manuscript preparation.
References Short Reviews must not exceed 60 references. References must be cited with superscript Arabic numerals in order of appearance and listed numerically, giving all authors’ names and initials unless there are more than 6 authors, in which case the first author should be followed by et al.
Figures & Tables Short Reviews must not exceed 4 figures, boxes, or tables. Figures must be uploaded separately from the manuscript, and tables must be submitted as editable text. Tables must be editable text with captions, and each figure or table must be cited and numbered consecutively in the text.
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Keynote Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must be 100 words.
Manuscript Manuscript must be 6000-7000 words. Manuscript must be divided into clearly defined sections using headings. Manuscript must include a 25-30-word teaser, 4 or 5 highlight statements of no more than 85 characters including spaces, a generative AI declaration section before the references if applicable, and 100-word author biographies with author photographs for up to three authors.
References References must not exceed 100. References must be cited in the text using superscript Arabic numerals in order of appearance, listed in the reference list in the same order, and give all authors’ names followed by initials without punctuation unless there are more than 6 authors, in which case the first author should be followed by et al.
Figures & Tables Figures, boxes, and tables must not exceed 7 in total. Figures must be uploaded separately from the manuscript, and tables must be submitted as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and include captions.
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Foundation Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must be 100 words.
Manuscript Manuscript must be 6000–7000 words. Manuscript must include a 25–30-word teaser, 4 or 5 highlight statements of no more than 85 characters including spaces, a generative AI declaration section before the references if AI was used, and 100-word author biographies with author photographs for up to three authors.
References References must not exceed 100. References must be cited in the text with superscript Arabic numerals in order of appearance, listed in the reference list in the same order, and show all authors unless there are more than 6 authors, in which case the first author is followed by et al.
Figures & Tables Figures, boxes, and tables must not exceed 7 in total. Figures must be uploaded separately from the manuscript, and tables must be submitted as editable text.
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Recent Publications

Microbial dysbiosis in metabolic disorders: linking epigenomic regulation and pathological mechanisms

Arun K Sharma, Md Sayeed Akhtar, Khalid Orayj, Sadaf Farooqui, Abida Khan, Gunjan Sharma

10.1016/j.drudis.2026.104698
View Publication

Advances in siRNA and synbiotic therapies for colorectal cancer: a molecular and microbiota perspective

Monika Vishwakarma, K. Anitha, Sumel Ashique, Neeraj Mishra

10.1016/j.drudis.2026.104697
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A statewide multi-institutional model that de-risks academic drug discovery

Suzanne Tomlinson-Mathis, Autumn Marsden, Zhiqiang An, Peter Davies, Dong Liang, Qingyun Liu, Tom Luby, Michael Mancini, Jennifer Maynard, Stanton McHardy, Margie Moczygemba, Clifford Stephan

10.1016/j.drudis.2026.104685
View Publication

Health and Medical Research in Australia II: A Golden Egg Opportunity Too Valuable to Underfund

Levon M. Khachigian

10.1016/j.drudis.2026.104693
View Publication

Artificial protein scaffolds for human therapeutics: drug discovery and delivery strategies

Amol D. Gholap, Pankaj Khuspe, Abdelwahab Omri

10.1016/j.drudis.2026.104689
View Publication

Frequently asked questions

How long does it take to publish?

4 days from submission to first decision; 38 days from submission to decision after review; 90 days from submission to acceptance; 5 days from acceptance to online publication.

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Is a cover letter required?

Submission is by invitation only. Prospective authors should first send a proposal with a brief 100-200 word description of the main theme, the article type, and if possible some key references.

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What are the publication costs?

Open access APC: USD 4480 excluding taxes for all article types. Subscription publication has no open access publication fee.

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Research Topics

Computational Drug Discovery Methods Biotechnology and Related Fields Pharmaceutical Economics and Policy Monoclonal and Polyclonal Antibodies Research RNA Interference and Gene Delivery Human auditory perception and evaluation Diverse Scientific and Economic Studies Pharmacogenetics and Drug Metabolism Chemical Synthesis and Analysis Biosimilars and Bioanalytical Methods Advanced biosensing and bioanalysis techniques Genetics, Bioinformatics, and Biomedical Research Click Chemistry and Applications Nanoparticle-Based Drug Delivery Science, Research, and Medicine Health Systems, Economic Evaluations, Quality of Life Receptor Mechanisms and Signaling Bioinformatics and Genomic Networks Analytical Chemistry and Chromatography 3D Printing in Biomedical Research CRISPR and Genetic Engineering Innovative Microfluidic and Catalytic Techniques Innovation RNA and protein synthesis mechanisms Protein Degradation and Inhibitors Protein Structure and Dynamics