EO

Expert Opinion On Therapeutic Targets

Expert Opinion on Therapeutic Targets is a MEDLINE-indexed, peer-reviewed, international subscription-based journal publishing review articles and original papers on novel molecular targets, with expert opinion on future drug development and drug discovery. It evaluates molecules, signalling pathways, receptors, and other therapeutic targets, focusing on molecular-level research and early preclinical studies rather than clinical information, specific drugs, or clinical trials.

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Impact Factor 4.4
Quartile Q1
Open Access Type Closed
ISSN 1472-8222
eISSN 1744-7631
Invitation Only No
Cost Range Institutional subscription: USD 9,941.00 online only or USD 14,556.00 print and online; local tax added as applicable.

Submission Instructions

Expert Opinion On Therapeutic Targets accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Original Research submissions must include a covering letter. The covering letter must provide the corresponding author’s full contact details and include statements of originality, all-author approval, ethical approval body, financial or other declarable relationships, and any abstract, poster, or oral presentation details.
Abstract Original Research articles must include a structured abstract. The abstract must be no more than 200 words. The abstract must be structured. The abstract should use the headings Background, Research design and methods, Results, and Conclusions.
Manuscript Original Research articles must include the sections introduction, patients and methods, results, discussion, and conclusions. Original Research articles must include 4–6 keywords in alphabetical order as well as title page, acknowledgements, author contributions, disclosure form, and disclosure statement sections.
References References must follow the journal’s NLM reference guide. References must be full, comprehensive, accurate, up to date, and annotated with one or two asterisks plus a brief explanatory sentence for papers or patents identified as of interest.
Figures & Tables A maximum of five figures and five tables is permitted. Tables must present new information, be interpretable without reference to the text, and be supplied as editable files.
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Review Article

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract of no more than 200 words is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order.
Manuscript Manuscript should use headings, sub-headings, and title paragraphs with Arabic numerals to indicate the hierarchy of headings and sub-headings. Manuscript must include 5–8 keywords, funding details, and a disclosure statement.
References References must follow the journal's NLM reference guide. References identified as of interest or of considerable interest must be marked with one or two asterisks and annotated with a brief explanatory sentence.
Figures & Tables A maximum of five figures and five tables is permitted. Tables must present new information, be interpretable without reference to the text, and be supplied as editable files.
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Systematic Review And Meta-Analysis

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured with the headings Introduction, Methods, Results, and Conclusions. Introduction, Methods, Results, and Conclusions are mandatory abstract headings.
Manuscript Article body must include the sections Introduction, Methods, Results, and Discussion. The manuscript must include 4 to 10 keywords in alphabetical order and registration details, including registration numbers where applicable.
References Around 100 references are suggested for a full-length review. References must follow the journal's NLM reference guide. Important references must be marked with one or two asterisks and accompanied by a brief annotation explaining their significance.
Figures & Tables Up to 5 figures and up to 5 tables are permitted. For each outcome, results must be presented for every study with summary statistics, an effect estimate, and its precision using tables and or plots.
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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Structured abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order.
Manuscript Letter to the Editor must be limited to 1500 words. Letter to the Editor must include the author's name, address, and contact details.
References Letter to the Editor must contain no more than 15 references. References must follow the journal's NLM reference guide. One reference must be the article under discussion.
Figures & Tables Letter to the Editor must not contain figures or tables.
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Drug Evaluation Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order.
Manuscript Manuscript should use headings, sub-headings, and title paragraphs with Arabic numerals to indicate hierarchy. Manuscript must include 5-8 keywords, funding details, and a disclosure statement.
References References must follow the journal's NLM reference guide. References identifying papers or patents of interest must be marked with one or two asterisks and annotated with a brief sentence explaining their significance.
Figures & Tables A maximum of five figures and five tables is permitted. Tables must present new information, be interpretable without reference to the text, and be supplied as editable files.
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Recent Publications

Therapeutic targeting of DNA repair pathway dysregulation in aging, cancer, and neurodegeneration

Vipin Kumar, Mohmmad Kashif, Vivek Singh, Rahul Singh Rawat, Aamir Khan, Gautam Chandra Sarkar, Misba Majood

10.1080/14728222.2026.2683686
View Publication

Insights into the therapeutic targeting of ASIC3 in pain: hurdles for clinical development

Chih-Hung Chi, Cheng-Han Lee, Chih-Cheng Chen

10.1080/14728222.2026.2682785
View Publication

RNA-centric approaches in amyotrophic lateral sclerosis: prospects for future therapeutics

Valentina La Cognata, Giulia Gentile, Giovanna Morello, Maria Guarnaccia, Sebastiano Cavallaro

10.1080/14728222.2026.2682782
View Publication

Investigating metabotropic glutamate receptors as molecular targets for next-generation pharmacotherapies for alcohol use disorder

Dominic Obraitis, Jason Barry, Dawei Li

10.1080/14728222.2026.2675555
View Publication

Targeting the OPA1 pathway in Autosomal Dominant Optic Atrophy (ADOA): 25 years from gene discovery to therapeutic strategy

Marcel V. Alavi

10.1080/14728222.2026.2671678
View Publication

Frequently asked questions

How long does it take to publish?

Accepted Author Version published online in 3 days provided the copyright form has been received. Accelerated Publication Plus offers a final decision in as little as 3 weeks from submission, first proofs within 5 working days, and online publication usually 1-2 weeks after acceptance. Accelerated Publication offers a final decision in as little as 9 weeks from submission, first proofs within 5 working days, and online publication usually 2-3 weeks after acceptance.

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Is a cover letter required?

A covering letter is required for complete submission. It should include corresponding author contact details, originality and exclusive submission statements, author approval statements, ethical approval information, and disclosure of financial or other declarable relationships.

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What are the publication costs?

Institutional subscription: USD 9,941.00 online only or USD 14,556.00 print and online; local tax added as applicable.

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Research Topics

Cytokine Signaling Pathways and Interactions MicroRNA in disease regulation PI3K/AKT/mTOR signaling in cancer Ion channel regulation and function Peptidase Inhibition and Analysis Epigenetics and DNA Methylation Cell death mechanisms and regulation Histone Deacetylase Inhibitors Research Angiogenesis and VEGF in Cancer Protein Kinase Regulation and GTPase Signaling Neuropeptides and Animal Physiology Neuroscience and Neuropharmacology Research Cancer, Hypoxia, and Metabolism Cancer Cells and Metastasis Cancer-related Molecular Pathways Ubiquitin and proteasome pathways Protease and Inhibitor Mechanisms Cancer Mechanisms and Therapy Receptor Mechanisms and Signaling Protein Degradation and Inhibitors HER2/EGFR in Cancer Research Nuclear Receptors and Signaling T-cell and B-cell Immunology Monoclonal and Polyclonal Antibodies Research Tryptophan and brain disorders