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Frontiers in Genome Editing

Frontiers in Genome Editing is an open-access journal that explores the applications of genome and epigenome editing technologies and their implications across wide-ranging areas of research.

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Subject Genetics & Heredity
Impact Factor 4.4
Quartile Q1
Open Access Type Open
eISSN 2673-3439
Invitation Only No
Cost Range Article processing charges (APCs) apply to articles that are accepted for publication.

Submission Instructions

Frontiers in Genome Editing accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph, for example following IMRAD.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion, with a succinct Introduction containing no subheadings. Manuscript must include 5 to 8 keywords, indicate the word count and number of figures and tables on the first page, acknowledge any generative AI use in the acknowledgements and methods section if applicable, and include all funding sources in a funding section.
References References must include only published or accepted works, list the first six authors followed by et al., abbreviate given names to initials, provide the DOI when available, and use 'in press' for accepted unpublished works.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be inserted directly into the manuscript. All figures or images must include alternative text, be cited in numerical order and mentioned in the text, and graphs must label each axis with units.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph. Abstract is required as part of the article format and should precede Introduction, Methods, Results, and Discussion.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Methods, Results, and Discussion, with Methods and Results including the specified systematic review subcomponents. Funding information must be included, and any use of generative AI must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source of the tool.
References References should list the first six authors followed by et al., include the DOI when available, and must not include unpublished material or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted into the manuscript. All figures or images should include alternative text and each figure and table must be mentioned in the text in numerical order.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. The first page must state the manuscript word count and number of figures and tables, include 5 to 8 keywords, and acknowledge any generative AI use in the acknowledgements and methods section if applicable.
References References must include only published or accepted works, list the first six authors followed by et al., provide DOIs when available, abbreviate given names to initials, use 'in press' for accepted unpublished works, and Review articles must not cite unpublished material or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted directly into the manuscript at the end in editable form. All figures and images must include alternative text, figures must be cited in numerical order with labeled panels where applicable, and tables must be cited in numerical order.
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured as a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. The first page must indicate the manuscript word count and number of figures and tables, the manuscript must include 5 to 8 keywords, and any use of generative AI must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source.
References References must list the first six authors followed by et al., include the DOI when available, and Mini Reviews must not cite unpublished material including submitted manuscripts or personal communications.
Figures & Tables Mini Review articles may include no more than 2 figures and/or tables in total. Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted directly into the manuscript at the end in editable form. All figures and images must include alternative text, figures must be cited in numerical order, and graphs must include self-explanatory axis labels with units.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph.
Manuscript Manuscript must not exceed 4,000 words. Manuscript should be organized as Abstract, Introduction, Method, Results, and Discussion. The first page must indicate the manuscript word count and the number of figures and tables, the manuscript must include 5 to 8 keywords, and any use of generative AI content must be acknowledged in the acknowledgements section and in the methods section if applicable with the name, version, model, and source listed.
References References must list the first six authors followed by et al., include DOI when available, use initials for given names, include only published or accepted works, and use 'in press' for accepted but unpublished works.
Figures & Tables Brief Research Reports may include no more than 4 figures and tables in total. Figures must be submitted individually with captions at the end of the manuscript, and tables must be directly inserted into the manuscript. All figures and images must include alternative text, each figure and table must be cited in the text in numerical order, and large tables spanning several pages must be published as supplementary material.
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Clinical Trial Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example according to the IMRAD format. Abstract must include the unique trial identifier and the URL of the publicly accessible trial registry website.
Manuscript Manuscript must include 5 to 8 keywords and acknowledge any use of generative AI in the acknowledgements section and in the methods section if applicable, including the name, version, model, and source of the tool.
References References must list the first six authors followed by et al., abbreviate given names to initials, provide the DOI when available, and ensure every in-text citation appears in the reference list and vice versa.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be directly inserted into the manuscript. All figures or images must include alternative text, and each figure and table must be mentioned in the text in numerical order.
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Recent Publications

CRISPR and Fanzor in sickle cell disease: current progress and future prospects

Aisha Yousef Alhumoudi, Aminah Ghazi Alotaibi, Nada Fahad Alosaimi, Abdulrahman Alshalani, Saad M. Alqahtani, Sarah M. Alsaab, Basem Jahz Almutiri, Mohammed M. H. Albariqi

10.3389/fgeed.2026.1774014
View Publication

A high-throughput, streamlined cloning protocol to generate guide RNAs for CRISPR activation

Shusen Zhu, Aura A. Tamez González, Abdelrahman Alokda, Jeremy M. Van Raamsdonk

10.3389/fgeed.2026.1787203
View Publication

Reconstructing the complex architecture of the genome with molecular scissors: applying genome editing technology in precision medicine

Md Nur Amin Khan, Rohit Das, Pooja Barik, Somasundaram Arumugam, Shiladitya Chattopadhyay

10.3389/fgeed.2026.1762449
View Publication

Commentary: CRISPR-Cas9 mediated editing of starch branching enzyme, SBE2 gene in potato for enhanced resistant starch for health benefits

Ling Yin

10.3389/fgeed.2026.1803282
View Publication

Advances in gene editing for legume improvement: technologies, progress, and prospects

Shallu Thakur, Shalini Pareek, G. P. Dixit, Geoffrey Meru, Alok Das

10.3389/fgeed.2026.1789952
View Publication

Frequently asked questions

How long does it take to publish?

Is a cover letter required?

What are the publication costs?

Article processing charges (APCs) apply to articles that are accepted for publication.

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Research Topics

CRISPR and Genetic Engineering Plant Virus Research Studies Virus-based gene therapy research Chromosomal and Genetic Variations Insect symbiosis and bacterial influences Animal Genetics and Reproduction Plant tissue culture and regeneration Genetically Modified Organisms Research RNA and protein synthesis mechanisms RNA regulation and disease Innovation and Socioeconomic Development Pluripotent Stem Cells Research RNA Interference and Gene Delivery Transgenic Plants and Applications Mosquito-borne diseases and control Advanced biosensing and bioanalysis techniques Genetics, Aging, and Longevity in Model Organisms CAR-T cell therapy research Photosynthetic Processes and Mechanisms Hemoglobinopathies and Related Disorders Cytomegalovirus and herpesvirus research Insect Resistance and Genetics Viral Infections and Immunology Research Retinal Development and Disorders Viral Infectious Diseases and Gene Expression in Insects

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