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Frontiers in Neurology

Frontiers in Neurology is an open access journal focused on neurological illness, advancing diagnosis, treatment, and prevention of brain and nervous system disorders to improve patient care.

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Subject Clinical Neurology, Neurosciences
Impact Factor 2.8
Quartile Q2
Open Access Type Open
ISSN 1664-2295
eISSN 1664-2295
Invitation Only No
Cost Range CHF 3,150 for A Type Articles; CHF 2,500 for B Type Articles.

Submission Instructions

Frontiers in Neurology accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must be structured and presented as a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion, or field-appropriate equivalents, with no subheadings in the Introduction. Manuscript must include 5 to 8 keywords, indicate the word count and number of figures and tables on the first page, and acknowledge any use of generative AI in the acknowledgements and in the Methods section if applicable.
References References must include all works cited in the text, list the first six authors followed by et al. with authors’ given names abbreviated to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, while tables must be inserted directly at the end of the manuscript in editable source form rather than submitted as figures. All figures and tables must be cited in the text in numerical order, figure panels must be labeled clearly, and all figures or images must include alternative text.
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for Systematic Review articles. The abstract must be structured and no longer than a single paragraph.
Manuscript The manuscript must not exceed 12,000 words. The manuscript should be organized as Abstract, Introduction, Methods, Results, and Discussion, with Methods including study design, participants, interventions, comparators, systematic review protocol, search strategy, data sources, study selection and data extraction, and data analysis, Results including a flow diagram of studies retrieved, study selection and characteristics, synthesized findings, and assessment of risk of bias, and Discussion including summary of main findings, limitations, and conclusions. The manuscript must clearly define the research question using PICOS, include funding information, and acknowledge any use of generative AI in the acknowledgements and methods section if applicable with the name, version, model, and source of the tool.
References References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and must not include unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Figures must be submitted individually, while tables must be inserted directly into the manuscript at the end in editable form and not submitted as figures. Figure captions must appear at the end of the manuscript, tables must be provided in editable source form, and all figures or images must include alternative text.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for review articles. The abstract must be structured and no longer than a single paragraph.
Manuscript Review articles must not exceed 12,000 words. Review articles must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. The manuscript must indicate the number of words and the number of figures and tables on the first page, include 5 to 8 keywords, and acknowledge any use of generative AI in the acknowledgements and in the methods section if applicable with the name, version, model, and source.
References References must include all works cited in the text, list the first six authors followed by et al. with authors’ given names abbreviated to initials, include the DOI when available, and exclude unpublished material, personal communications, and works not published or accepted.
Figures & Tables Figures must be submitted individually, while tables must be directly inserted at the end of the manuscript in editable source form and not submitted as figures. Each figure and table must be cited in numerical order in the text, figure captions must be placed at the end of the manuscript, and large multi-page tables must be published as supplementary material.
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Policy And Practice Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured and presented as a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be organized as Abstract, Introduction, sections on assessment of policy or guidelines options and implications, Actionable Recommendations, and Discussion. The first page must indicate the manuscript word count and the number of figures and tables, the manuscript must include 5 to 8 keywords, and any use of generative AI must be acknowledged in the acknowledgements and methods section if applicable with the name, version, model, and source of the tool.
References References must include the first six authors followed by et al. and the DOI when available, with authors’ given names abbreviated to initials.
Figures & Tables Figures must be submitted individually, while tables must be inserted directly into the manuscript at the end. All figures or images must include alternative text, figure captions must be placed at the end of the manuscript, and tables must be provided in editable source form rather than as figures.
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Clinical Trial

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. The abstract must be structured and presented as a single paragraph. The abstract must include the clinical trial registry number, the trial unique identifier, and the URL of the publicly accessible trial registry website.
Manuscript The manuscript must not exceed 12,000 words. The manuscript should be organized as Abstract, Introduction, Materials and Methods, Results, and Discussion. The manuscript must acknowledge any use of generative AI in the acknowledgements and in the methods section if applicable, and a flow diagram must be included in Materials and Methods when applicable.
References References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually, while tables must be inserted directly into the manuscript at the end in editable source form and not submitted as figures. All figures or images must include alternative text, and randomized clinical trials must include a CONSORT flow diagram in the figures or supplementary material.
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must be structured and limited to a single paragraph.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must be organized as Abstract, Introduction, subject-relevant subsections, and Discussion. Manuscript should discuss different schools of thought or controversies, current research gaps, potential future developments, include 5 to 8 keywords, and acknowledge any use of generative AI in the acknowledgements and methods section if applicable.
References References must include only published or accepted works, list the first six authors followed by et al. with authors’ given names abbreviated to initials, include DOI when available, and exclude unpublished material or personal communications.
Figures & Tables Manuscript may include no more than 2 figures or tables in total. Figures must be submitted individually, while tables must be inserted directly at the end of the manuscript in editable form. All figures must include alternative text, be cited in numerical order in the text, and captions for figures and tables must use the appropriate labels with figure captions placed at the end of the manuscript.
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Case Report

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required for Case Reports. The abstract must be structured and presented as a single paragraph.
Manuscript The manuscript must not exceed 3,000 words. Case Reports should be organized as Abstract, Introduction, Case description, a figure or table presenting a care timeline, Diagnostic assessment with details on the therapeutic intervention, follow-up and outcomes, Discussion, and Patient perspective. The manuscript must include 5 to 8 keywords, indicate the word count and number of figures and tables on the first page, acknowledge any use of generative AI in the acknowledgements and methods if applicable, and use the title format "Case Report: 'area of focus'".
References References must list the first six authors followed by et al., abbreviate given names to initials, include DOIs when available, and ensure all in-text citations appear in the reference list and vice versa.
Figures & Tables Case Reports may include no more than 4 display items in total, including figures, tables, or videos. Figures must be submitted individually, while tables must be inserted directly into the manuscript at the end. The manuscript should include a figure or table showing a timeline with relevant data from the episode of care, and all figures must include alternative text.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. The abstract must be structured and presented as a single paragraph.
Manuscript The manuscript must not exceed 4,000 words. The manuscript should be organized as Abstract, Introduction, Method, Results, and Discussion. The first page must indicate the manuscript word count and the number of figures and tables, include 5 to 8 keywords, and acknowledge any use of generative AI in the acknowledgements and in the methods section if applicable with the tool name, version, model, and source.
References References must include all cited items only, list the first six authors followed by et al. when applicable, abbreviate given names to initials, include the DOI when available, and use 'in press' for accepted unpublished works.
Figures & Tables No more than 4 figures or tables may be included. Figures must be submitted individually, while tables must be inserted directly into the manuscript at the end in editable source form and not submitted as figures. All figures and tables must be cited in the text in numerical order, figure captions must appear at the end of the manuscript, table captions must appear immediately before each table, and figures should include alternative text.
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Technology And Code

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured and presented as a single paragraph.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized as Abstract, Introduction, Method, Results, and Discussion. Manuscript must include the project link, operating system, programming language, any restrictions for non-academic use, code description in the Method section, examples of use and limitations in the Results section, scalability and limitations in the Discussion section, and an acknowledgment of any generative AI use in the acknowledgements and methods if applicable.
References References must list the first six authors followed by et al. and include the DOI when available.
Figures & Tables Figures must be submitted individually, and tables must be inserted directly into the manuscript at the end in editable source form. All figures or images must include alternative text.
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Recent Publications

Angiography-derived fractional flow and clinical outcomes in symptomatic intracranial atherosclerotic stenosis

Wanning Zheng, Rong Zou, Ming Wang, Jiahao Tang, Ruilin Chen, Chaobo Zheng, Jie Gong, Yuhai Gao, Ning Wang, Yuning Lu, Jiong Wu, Jens Fiehler, Adnan H. Siddiqui, Jianping Xiang, Shu Wan

10.3389/fneur.2026.1944177
View Publication

Metagenomic next-generation sequencing confirmed pseudorabies virus encephalitis complicated with central visual impairment: a case report

Yonghu Zhang, Xiaojing Zhang, Xue Wei, Wenwen Yu, Ning Ma, Weihai Liu, Yafeng Zheng, Hongyu Jia

10.3389/fneur.2026.1954544
View Publication

Latent class analysis identifies three biologically distinct phenotypes among patients undergoing endovascular thrombectomy: a derivation and temporal validation study

Li-Li Yang, Chao Chen, Li-Li Sun, Meng-Xia Li, Li Han

10.3389/fneur.2026.1855033
View Publication

Deep learning–accelerated contrast-enhanced 3D MRI for acute optic neuritis: faster acquisition and improved lesion conspicuity

Ying Liu, Weiyin Vivian Liu, Zhi Wen, Min Lu, Changsheng Liu, Liang Li, Ting Chen, Renjie Yang, Yunfei Zha

10.3389/fneur.2026.1954788
View Publication

A facet joint landmark-guided approach for multi-segmental DRG injection with limited bone removal in mice

Ruohan Yan, Sike Sun, Zipeng Zhou, Lei Ma, Junhao Deng, Jinhui Zhang

10.3389/fneur.2026.1956927
View Publication

Frequently asked questions

How long does it take to publish?

Is a cover letter required?

A traditional cover letter is not allowed. Authors must instead prepare a 200-word contribution-to-the-field statement.

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What are the publication costs?

Article processing charges are CHF 3,150 for A Type Articles and CHF 2,500 for B Type Articles. Discounts or full or partial support may be available through institutional partnerships and author support programs.

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Research Topics

Acute Ischemic Stroke Management Stroke Rehabilitation and Recovery Traumatic Brain Injury and Neurovascular Disturbances Parkinson's Disease Mechanisms and Treatments Vestibular and auditory disorders Intracerebral and Subarachnoid Hemorrhage Research Cerebrovascular and Carotid Artery Diseases Neurological disorders and treatments Epilepsy research and treatment Traumatic Brain Injury Research Intracranial Aneurysms: Treatment and Complications Multiple Sclerosis Research Studies Functional Brain Connectivity Studies Transcranial Magnetic Stimulation Studies Botulinum Toxin and Related Neurological Disorders Hearing, Cochlea, Tinnitus, Genetics Dementia and Cognitive Impairment Research Migraine and Headache Studies Peripheral Neuropathies and Disorders Neuroinflammation and Neurodegeneration Mechanisms Balance, Gait, and Falls Prevention Genetic Neurodegenerative Diseases Cerebral Palsy and Movement Disorders Advanced Neuroimaging Techniques and Applications EEG and Brain-Computer Interfaces

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