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Frontiers In Synaptic Neuroscience

Frontiers in Synaptic Neuroscience is part of a neuroscience journal series and publishes research advancing understanding of synaptic structure, function, plasticity, and alterations in disease.

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Subject Neurosciences
Impact Factor 4.1
Quartile Q1
Open Access Type Open
ISSN 1663-3563
eISSN 1663-3563
Invitation Only No
Cost Range CHF 3,150 for A-Type Articles; CHF 2,500 for B-Type Articles.

Submission Instructions

Frontiers In Synaptic Neuroscience accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured as a single paragraph, for example following IMRAD.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be formatted with the sections Abstract, Introduction, Materials and Methods, Results, and Discussion, or field-appropriate equivalents. Manuscript must include 5 to 8 keywords, and any use of generative AI for written or visual content must be acknowledged in the acknowledgements with the name, version, model, and source.
References References must follow either Harvard or Vancouver style, according to the journal. References must list the first six authors followed by et al., abbreviate given names to initials, and include the DOI when available.
Figures & Tables Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Each figure and table must be mentioned in the text, and figure panels should be labeled with capital letters such as (A), (B), and (C).
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Systematic Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript should be formatted with the sections Abstract, Introduction, Methods, Results, and Discussion, and it must clearly define the research question in terms of PICOS. Manuscript must include at least five and no more than eight keywords, acknowledge any generative AI use in the acknowledgements with the tool name, version, model, and source, include funding information, and indicate the manuscript word count on the first page.
References References must adhere to either Harvard or Vancouver style, according to the journal. References must list the first six authors followed by et al. and include the DOI when available, and Systematic Review articles must not cite unpublished material, submitted manuscripts, or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in an editable format. Each figure and table must be mentioned in the text, and all figures or images should include alternative text.
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Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be formatted with the sections Abstract, Introduction, subject-relevant subsections, and Discussion. Manuscript must include 5 to 8 keywords and acknowledge any written or visual content produced by or edited using generative AI in the acknowledgements section with the tool name, version, model, and source.
References References must follow either Harvard or Vancouver style, according to the journal. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and must not include unpublished material or personal communications.
Figures & Tables Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text, and large tables covering several pages must be published as supplementary material.
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Mini Review

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph.
Manuscript Manuscript must not exceed 3,000 words. Manuscript must be formatted with the sections Abstract, Introduction, subject-relevant subsections, and Discussion. Manuscript must include 5 to 8 keywords and acknowledge any use of generative AI in the acknowledgements section with the tool name, version, model, and source.
References References must follow either Harvard or Vancouver style, according to the journal. References must list the first six authors followed by et al., include author initials and DOI when available, and must not include unpublished material or personal communications.
Figures & Tables Mini Review articles may include no more than 2 figures or tables. Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text.
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Data Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract should be structured in a single paragraph, for example following IMRAD format.
Manuscript Manuscript must not exceed 3,000 words. Manuscript should include Introduction and Methods used to collect the data with relevant subsections, and it must not include Results or Discussion sections. Manuscript must include the dataset name, the database or repository where it has been submitted, the confidential peer-review link to the dataset, at least five and no more than eight keywords, and an acknowledgements statement disclosing any generative AI use with the tool name, version, model, and source.
References References must follow either Harvard or Vancouver style, according to the journal. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and include deposited datasets with version and unique identifier when available.
Figures & Tables Data Report articles may include no more than 2 figures or tables in total. Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Each figure and table must be mentioned in the text, and figures or images must include alternative text.
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Brief Research Report

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be a single paragraph and should be structured, for example according to the IMRAD format.
Manuscript Manuscript must not exceed 4,000 words. Manuscript should be formatted with the sections Abstract, Introduction, Method, Results, and Discussion. Manuscript must include 5 to 8 keywords, indicate the total word count on the first page, and acknowledge any use of generative AI in the acknowledgements section with the tool name, version, model, and source.
References References must follow either Harvard or Vancouver style. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and include only works that are published or accepted.
Figures & Tables Brief Research Report articles may contain no more than 4 figures or tables. Figures must be submitted individually with captions placed at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. All figures or images must include alternative text, and each figure and table must be mentioned in the text.
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Fair² Data

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be structured in a single paragraph, for example following the IMRAD format.
Manuscript Manuscript must not exceed 12,000 words. Manuscript must be organized by headings and subheadings. Manuscript must include at least 5 and no more than 8 keywords, acknowledge any generative AI use in the acknowledgements with the tool name, version, model, and source, and indicate the manuscript word count on the first page.
References References must follow either Harvard or Vancouver style, according to the journal. References must list the first six authors followed by et al., abbreviate given names to initials, include the DOI when available, and include only published or accepted works.
Figures & Tables Fair² Data articles may include up to 15 figures or tables. Figures must be submitted individually with captions at the end of the manuscript, and tables must be inserted at the end of the manuscript in editable format. Figures and tables must each be mentioned in the text, and figure panels must be labeled with letters such as (A), (B), and (C).
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Recent Publications

NMDA receptor mediated tonic excitatory currents are elicited by EAAT inhibition on human neocortical pyramidal neurons

Béla Márton, Levente Ecsedi, Krisztina Pocsai, Abdennour Douida, Karri Lamsa, Gábor Hutóczki, Álmos Klekner, Balázs Pál

10.3389/fnsyn.2026.1844197
View Publication

Suicidality as a potential risk and therapeutic target during widespread GLP-1 receptor agonists use: implications of inflammation

Milica M. Borovcanin, Ivica Petrovic

10.3389/fnsyn.2026.1869086
View Publication

Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture

John Carl Begley, Harald Prüss, Paul Turko, Camin Dean

10.3389/fnsyn.2026.1832103
View Publication

Synaptosomes isolated from cryopreserved MND motor cortex reveal altered calcium handling and reduced complex IV–linked respiration

Sean D. Morrison, Lotten Ragnarsson, Sarah O. Cook, Joseph A. Rothnagel, Ernst Wolvetang, Bahaa Al-mhanawi, Mohammed R. Shaker, Thomas Robertson, Peter R. Dodd, Peter G. Noakes

10.3389/fnsyn.2026.1760254
View Publication

Experience-dependent critical period for synaptic plasticity in the rat olfactory amygdala

Belén Aburto-Ponce, Pedro Fernández-Aburto, Jorge Mpodozis, Juan Bacigalupo, Magdalena Sanhueza

10.3389/fnsyn.2026.1779075
View Publication

Frequently asked questions

How long does it take to publish?

Average 90 days from submission to acceptance and 12 days from acceptance to the final typeset document.

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Is a cover letter required?

A traditional cover letter is not accepted. Authors must instead prepare a 200-word statement describing the manuscript’s contribution to the field.

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What are the publication costs?

Article processing charges are CHF 3,150 for A-Type Articles and CHF 2,500 for B-Type Articles. APC support or discounts may be available through institutional partnerships and for eligible authors with insufficient funding.

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Research Topics

Neuroscience and Neuropharmacology Research Neural dynamics and brain function Photoreceptor and optogenetics research Cellular transport and secretion Neuroscience and Neural Engineering Memory and Neural Mechanisms Advanced Memory and Neural Computing Lipid Membrane Structure and Behavior Receptor Mechanisms and Signaling Neurotransmitter Receptor Influence on Behavior Ion channel regulation and function Neuroinflammation and Neurodegeneration Mechanisms Neurogenesis and neuroplasticity mechanisms Genetics and Neurodevelopmental Disorders Retinal Development and Disorders Nicotinic Acetylcholine Receptors Study Advanced Fluorescence Microscopy Techniques Mitochondrial Function and Pathology Alzheimer's disease research and treatments Autism Spectrum Disorder Research Neurobiology and Insect Physiology Research Nerve injury and regeneration Hearing, Cochlea, Tinnitus, Genetics Neurological disorders and treatments Stress Responses and Cortisol

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