GR

Genome Research

Genome Research is an international, continuously published, peer-reviewed journal that features original research providing novel insights into the genome biology of all organisms, including advances in genomic medicine. The journal also publishes reviews and perspectives and reports computational biology and high-throughput methodologies.

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Subject Genetics & Heredity
Impact Factor 5.5
Quartile Q1
Open Access Type Hybrid
ISSN 1088-9051
eISSN 1549-5469
Invitation Only No

Submission Instructions

Genome Research accepts the following article types. Click on an article type to view submission instructions.

Research

Cover Letter A cover letter is required. Cover letter must highlight the main points and suitability of the work, state the status of any personal communications or other permissions, describe databank submission of data, and assure that gene and protein names and symbols follow approved nomenclature guidelines.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract structure is not specified.
Manuscript Manuscript length must be between two and 12 journal pages. Manuscript must be ordered as Title Page, Abstract, Introduction, Results, Discussion, Methods, Data Access, Competing Interest Statement, Acknowledgments, and References, and Results and Discussion must not be combined. Methods must include a Software availability section as appropriate, Data Access must include accession numbers for newly generated data or reviewer links when accessions are not yet public, and Author Contributions must appear at the end of Acknowledgments.
References References must use a name-date style. References must be listed alphabetically, cited in text as surname-date with et al. for more than two authors, include all authors up to 10 and the first 10 followed by et al. for more than 10, and journal references must be formatted as surname and initials, year, article title, abbreviated journal title, volume, and full page range.
Figures & Tables Initial submissions must embed all figures and tables in the main document near their first citation, with figure legends adjacent to the relevant figure. Tables essential for reproduction but not understanding and lengthy tables should be submitted as Supplemental Material.
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Methods

Cover Letter A cover letter is required. The cover letter must include a paragraph highlighting the main points of the work and its suitability, the status of any personal communication or permission statements, a statement regarding databank submission of data, and assurance that gene and protein names and symbols follow approved nomenclature guidelines.
Abstract An abstract is required. Abstract cannot exceed 250 words.
Manuscript Paper length must be between two and 12 journal pages. Manuscript sections must be ordered as Title Page, Abstract, Introduction, Results, Discussion, Methods, Data Access, Competing Interest Statement, Acknowledgments, and References, and Results and Discussion may not be combined. Methods must include a Software availability section at the end as appropriate, Data Access must include public database accession numbers for newly generated data or reviewer links when accessions are not yet public, and Author Contributions must appear at the end of Acknowledgments.
References References must use a name-date style. Article and book references must be cited in text as name-date, the reference list must be in alphabetical order, references with 10 or fewer authors must list all authors, and references with more than 10 authors must list the first 10 followed by et al.
Figures & Tables For first submission, all figures and tables must be embedded near the place of first citation within the main document, with figure legends adjacent to the relevant figure. Tables essential for reproducing the work but not essential for understanding the paper and lengthy tables should be submitted as Supplemental Material.
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Resource

Cover Letter A cover letter is required. Cover letter must highlight the main points of the work and its suitability, state the status of any personal communications or other permissions, include a statement regarding databank submission of data, and assure approved gene and protein nomenclature is used.
Abstract An abstract is required. Abstract must not exceed 250 words.
Manuscript Paper length must be between two and 12 journal pages, and Resource articles are expected to be much more succinct. Manuscript sections must be ordered as Title Page, Abstract, Introduction, Results, Discussion, Methods, Data Access, Competing Interest Statement, Acknowledgments, and References, with Results and Discussion kept separate. Methods must include a Software availability section as appropriate, Data Access must include accession numbers or reviewer links as applicable, and Author Contributions must appear at the end of Acknowledgments.
References References must use name-date citation style. Reference list must be in alphabetical order, include all authors when there are 10 or fewer or the first 10 followed by et al. when there are more than 10, and format journal references with surname and initials, year, article title, abbreviated journal title, volume, and complete page range.
Figures & Tables For initial submission, all figures and tables must be embedded near their first citation within the main document, with figure legends adjacent to the relevant figure. Tables essential for reproduction but not understanding and lengthy tables should be submitted as Supplemental Material.
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Recent Publications

Knowledge-driven interpretable neural networks for mechanistic insight

Yan Ke, Tianwei Yu

10.1101/gr.281686.125
View Publication

Fast and memory efficient partial order alignment with minipoa

Haodong Liu, Pinglu Zhang, Yanming Wei, Qinzhong Tian, Yixiao Zhai, Quan Zou, Mengting Niu

10.1101/gr.282046.126
View Publication

Jim Watson (1928–2025): a genomics visionary

Aravinda Chakravarti, Evan E. Eichler, Anne C. Ferguson-Smith, Richard A. Gibbs, Eric D. Green, John R. Inglis, Kateryna D. Makova, Richard M. Myers, Hillary E. Sussman

10.1101/gr.282580.126
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Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI

Peimeng Zhen, Han Shu, Bingtao Wang, Yongtian Wang, Jialu Hu, Jiajie Peng, Xuequn Shang, Tao Wang, Jing Chen

10.1101/gr.281568.125
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Multisource omic alignment and biological feature discovery with Performer encoder and triplet networks

Zihuan Du, Xiaoyu Zhang, Qiang Zhang, Jing Li, Zhijie Cao, Ge Gao, Tao Lin, Dong Wang, Shuai Gao

10.1101/gr.281629.125
View Publication

Frequently asked questions

How long does it take to publish?

Is a cover letter required?

A cover letter is required and must include a paragraph highlighting the main points of the work and its suitability for Genome Research, the status of personal communications or other permissions, a statement regarding databank submission of data, and assurance that gene and protein names and symbols adhere to approved nomenclature guidelines. Related manuscripts in press, submitted, or in preparation must be disclosed.

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What are the publication costs?

Open access publishing is available.

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Research Topics

Genomics and Phylogenetic Studies RNA and protein synthesis mechanisms Genomics and Chromatin Dynamics Chromosomal and Genetic Variations RNA Research and Splicing RNA modifications and cancer CRISPR and Genetic Engineering Epigenetics and DNA Methylation Genomic variations and chromosomal abnormalities Molecular Biology Techniques and Applications Gene expression and cancer classification Genetic Mapping and Diversity in Plants and Animals Bioinformatics and Genomic Networks Genetic diversity and population structure Cancer Genomics and Diagnostics Single-cell and spatial transcriptomics Cancer-related molecular mechanisms research Genetic Associations and Epidemiology Genomics and Rare Diseases Fungal and yeast genetics research Animal Genetics and Reproduction Bacteriophages and microbial interactions DNA Repair Mechanisms Machine Learning in Bioinformatics Evolution and Genetic Dynamics

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