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Immunity & Ageing

Immunity & Ageing explores all aspects of ageing from an immunological point of view. It specializes in the impact of ageing on immune systems, the influence of aged immune systems on organismal well-being and longevity, age-associated diseases with at least partial immune etiology, and potential immune interventions to increase health span.

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Subject Geriatrics & Gerontology, Immunology
Impact Factor 5.6
Quartile Q1
Open Access Type Open
ISSN 1742-4933
eISSN 1742-4933
Invitation Only No
Cost Range APC: £2590.00 GBP / $3390.00 USD / €2890.00 EUR, plus VAT or local taxes where applicable.

Submission Instructions

Immunity & Ageing accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter A cover letter is required with the submission. The cover letter must declare any potential competing interests and confirm that all authors approved the manuscript for submission.
Abstract An abstract is required for Research Articles. Abstract must not exceed 350 words. Abstract must be structured. Abstract must include the headings Background, Results, and Conclusions.
Manuscript Manuscript must include the sections Background, Methods, Results, Discussion, Conclusions, and a Declarations section. Manuscript must include three to ten keywords, the Declarations subheadings Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and Authors' information (optional), use 'Not applicable' for any irrelevant Declarations section, and document any use of a Large Language Model in the Methods section or a suitable alternative part if no Methods section is available.
References References must use Vancouver style. Web links and URLs must be cited with a reference number and listed in full in the reference list, and unpublished abstracts, unpublished data, and personal communications must not be included in the reference list.
Figures & Tables Tables less than one page may be placed within the manuscript, tables larger than one page may be placed at the end of the text file, and figure titles and legends must be provided in the main manuscript rather than in the graphic file. Figures and tables must be numbered in the order they are cited in the text, tables must not be embedded as figures or spreadsheet files, and tables must be created using the word processor's Table object function.
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Review Articles

Cover Letter A cover letter is required, and unsolicited review submissions must include evidence of the authors' high-level expertise. The cover letter must declare any potential competing interests, confirm that all authors approved the submission, confirm the manuscript has not been published or submitted elsewhere, name the special issue if applicable, and for unsolicited reviews include 5 to 10 relevant publications with links.
Abstract An abstract is required for review articles. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include Background, Main body of the abstract, and short Conclusion.
Manuscript Review articles must not exceed 20 typeset pages, including figures, tables and references. The manuscript must include Background, Main text, Conclusions, and a Declarations section. The manuscript must include 3 to 10 keywords, a list of abbreviations if abbreviations are used, and under Declarations the headings Ethics approval and consent to participate, Consent for publication, Availability of data and materials, Competing interests, Funding, Authors' contributions, Acknowledgements, and optional Authors' information, with 'Not applicable' used for any non-relevant declaration section.
References References must follow Vancouver style. Only articles, clinical trial registration records, and abstracts that are published, in press, or publicly available as e-prints or preprints may be cited, unpublished abstracts, unpublished data, and personal communications must be excluded from the reference list, journal abbreviations must follow Index Medicus/MEDLINE, and web links or URLs must be numbered and included in the reference list.
Figures & Tables Tables shorter than one page may be placed within the manuscript, larger tables may be placed at the end of the text file, tables too wide for a landscape page may be uploaded as additional files, and figure titles and legends must appear in the main manuscript rather than in the graphic file. Figures and tables must be numbered in the order cited, multi-panel figures must be submitted as a single composite file, tables must not be embedded as figures or spreadsheet files, and tables must be created using the word processor's table function.
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Correspondence

Cover Letter A cover letter is required with the submission. The cover letter must declare any potential competing interests and confirm that all authors approved the manuscript for submission.
Abstract An abstract is required for Correspondence manuscripts. Abstract must not exceed 250 words. The abstract is unstructured.
Manuscript Main text should contain the body of the article and may be divided into subsections with short informative headings, and the manuscript must include a Declarations section with the required subheadings. The manuscript must include three to ten keywords, a Declarations section containing the required subheadings with 'Not applicable' where relevant, a list of abbreviations if abbreviations are used, and documentation of any Large Language Model use in the Methods section or another suitable section if no Methods section is available.
References References must use the Vancouver style. Web links and URLs must be cited with a reference number and included in the reference list in full with the site title, URL, and access date.
Figures & Tables Tables shorter than one page may be placed within the manuscript, while longer tables may be placed at the end of the text file and figures must be provided separately with titles and legends in the main manuscript. Figures and tables must be numbered in the order cited in the text, and tables must not be embedded as figures or spreadsheet files.
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Brief Reports

Cover Letter A cover letter is required. Cover letter must declare any potential competing interests and confirm that all authors approved the submission.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract should be unstructured and briefly summarize the aim, findings, or purpose of the article. null
Manuscript null Manuscript must include a title page and a Declarations section with the subheadings 'Ethics approval and consent to participate', 'Consent for publication', 'Availability of data and materials', 'Competing interests', 'Funding', 'Authors' contributions', and 'Acknowledgements'. Manuscript must include three to ten keywords, a list of abbreviations if abbreviations are used, and documentation of any Large Language Model use in the Methods section or suitable alternative section.
References null References must follow Vancouver style. Web links and URLs must be assigned a reference number and included in the reference list in full with the site title, URL, and access date.
Figures & Tables null Tables shorter than one page may be placed within the manuscript, while larger tables may be placed at the end of the text file or uploaded separately if too wide. Figure titles and table titles must not exceed 15 words, and figure legends and table legends must not exceed 300 words.
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Comment

Cover Letter A cover letter is required with the submission. The cover letter must declare any potential competing interests and confirm that all authors have approved the manuscript for submission.
Abstract An abstract is required. The abstract must not exceed 350 words. The abstract must be structured. The abstract must include background, main body of the abstract, and short conclusion.
Manuscript Comments must include Background, Main text, Conclusions, and a Declarations section with all required subheadings. Comments must include three to ten keywords and all Declarations subheadings, with any non-relevant sections retained and marked 'Not applicable'.
References References must follow the Vancouver reference style. Web links and URLs must be assigned a reference number and included in the reference list rather than in the text.
Figures & Tables Tables less than one page may be placed in the manuscript, while larger tables may be placed at the end of the text file. Figures and tables must be numbered in the order cited in the text, with figure titles and legends provided in the main manuscript.
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Recent Publications

CD8+ effector memory and regulatory T cell dynamics predict subclinical atherosclerotic plaque formation in healthy aging

Christopher Weyh, Vincent Größer, Luciele Guerra Minuzzi, Torsten Frech, Kristina Gebhardt, Svenja Nolte, Theresa Regine Dombrowski, Tim Böttrich, Manuela Andrea Hoffmann, Natascha Sommer, Robert Ringseis, Klaus Eder, Samuel Sossalla, Pascal Bauer, Karsten Krüger

10.1186/s12979-026-00588-2
View Publication

JUND-DNAJB1-p21 axis drives fibroblast senescence to recruit CD4⁺ T cells in salivary gland pathogenesis of Sjögren’s disease

Yingliang Shi, Yi Guo, Hanlin Tu, Jiaqi Yue, Zhongyang Zou, Yuyan He, Jing Zhou, Xiang Li, Sangang He, Guoliang Sa

10.1186/s12979-026-00590-8
View Publication

Hyperbaric oxygen therapy modulates immune aging in a personalized manner: a linear mixed-effects analysis

Hai-Tao Chu, Hang Zhao, Shan-Shan Wang, Xin Meng, Di Wang, Xiao-Bo Zhu, Yang Wang, Xue-Wei Yang

10.1186/s12979-026-00587-3
View Publication

Macrophage senescence and senescence-like states in senile osteoporosis: cellular cross-talk and therapeutic perspectives

Qinfeng Zhou, Kaixuan Wang, Xiaoxian Sun, Jingyue Fu, Lei Wang, Qing Wang, Yong Ma, Yang Guo

10.1186/s12979-026-00586-4
View Publication

Exaggerated thymic involution in late-onset myasthenia gravis: clinical and immunological evidence

Yu-Xin Wang, Tong Du, Heng Li, Peng-Xi Han, Chang Liu, Jia-Meng Lu, Xiao-Li Li, Bin Liu, Yu-Yao Zhai, Xin-Hua Zhao, Guang-You Duan, Rui-Sheng Duan, Min Zhang

10.1186/s12979-026-00589-1
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 4 days.

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Is a cover letter required?

Unsolicited reviews may be considered from authors active in the field, and contacting the editors before submission is preferred.

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What are the publication costs?

Research Topics

Immune Cell Function and Interaction T-cell and B-cell Immunology Neuroinflammation and Neurodegeneration Mechanisms Cytomegalovirus and herpesvirus research Immune Response and Inflammation Adipokines, Inflammation, and Metabolic Diseases Tryptophan and brain disorders Immune cells in cancer Immunotherapy and Immune Responses Diabetes and associated disorders COVID-19 Clinical Research Studies SARS-CoV-2 and COVID-19 Research Influenza Virus Research Studies Long-Term Effects of COVID-19 Alzheimer's disease research and treatments Immune responses and vaccinations Genetics, Aging, and Longevity in Model Organisms Telomeres, Telomerase, and Senescence Neutrophil, Myeloperoxidase and Oxidative Mechanisms IL-33, ST2, and ILC Pathways Nutrition and Health in Aging Atherosclerosis and Cardiovascular Diseases Single-cell and spatial transcriptomics Frailty in Older Adults Gut microbiota and health

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