IL

Immunology Letters

Immunology Letters is the official journal of the European Federation of Immunological Societies (EFIS), published by Elsevier. It publishes experimental papers, mini-reviews, reviews, letters to the editor, and commentaries addressing molecular, cellular, and clinical immunology, with emphasis on clarity, experimental soundness, novelty, and work of immediate importance to investigators.

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Subject Immunology
Impact Factor 2.8
Quartile Q3
Open Access Type Hybrid
ISSN 0165-2478
eISSN 1879-0542
Invitation Only No
Cost Range USD 3290 APC for open access articles; no open access publication fee for subscription publication.

Submission Instructions

Immunology Letters accepts the following article types. Click on an article type to view submission instructions.

Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A concise and factual abstract is required. The abstract should be unstructured and able to stand alone.
Manuscript Research Articles have no page limit but may be returned for shortening at the editors' discretion. Articles must be divided into clearly defined and numbered sections. Manuscripts must include highlights of 3 to 5 bullet points in a separate editable file, a maximum of 6 keywords immediately after the abstract, a competing interests statement, and an AI-use disclosure section before the references if generative AI was used in manuscript preparation.
References References in the text must be indicated by number in square brackets. References must be numbered in the order they appear in the text, and journal names should be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Each illustration must be submitted as a separate file, and all figures and tables must be uploaded with figure captions provided separately and tables including titles, descriptions, and footnotes. Figures must be numbered according to their sequence in the text, and tables must be submitted as editable text and numbered consecutively in accordance with their appearance in the text.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A concise and factual abstract is required. The abstract should be unstructured and able to stand alone.
Manuscript Articles must be divided into clearly defined and numbered sections with numbered subsections. Manuscripts must include highlights consisting of 3 to 5 bullet points of no more than 85 characters each, up to 6 keywords after the abstract, a declaration of interest statement, and an AI-use disclosure section before the references if generative AI was used.
References References must be cited by number in square brackets. References must be numbered in the order of appearance in the text, every reference list entry must be cited in the text and vice versa, and journal names should be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Each figure must be uploaded as a separate file with its caption provided separately, and all tables must be uploaded with titles, descriptions, and footnotes. Figures and tables must be numbered consecutively according to their order in the text, tables must be editable text rather than images, and figure and table citations in the text must match the files provided.
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Current Views

Cover Letter All authors must approve the submission, and any use of generative AI tools in manuscript preparation must be declared upon submission.
Abstract A concise and factual abstract is required. The abstract must be unstructured and able to stand alone.
Manuscript Articles must be divided into clearly defined and numbered sections. Manuscripts must include highlights of 3 to 5 bullet points, a maximum of 6 keywords after the abstract, a declaration of interest statement, and an AI-use disclosure section before the references if generative AI was used.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance in the text, and journal names should be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Figures and tables must be uploaded as separate files with captions or titles and cited in the text. Each illustration and table must be numbered consecutively according to its appearance in the text, and tables must be submitted as editable text rather than images.
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Correspondence

Cover Letter Cover Letter requirements are not specified.
Abstract A concise and factual abstract is required. Abstract should be unstructured and able to stand alone.
Manuscript Correspondence should normally not exceed 800 words. Articles must be divided into clearly defined and numbered sections. Manuscripts must include highlights of 3 to 5 bullet points in a separate editable file, a maximum of 6 keywords after the abstract, a competing interests statement, and an AI-use disclosure section before the references if generative AI tools were used.
References References must be cited by number in square brackets. References must be numbered in the order they appear in the text, and journal names should be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Each illustration must be submitted as a separate file, and figures and tables must be uploaded with matching citations in the text. Each figure must have a separate caption, and tables must be submitted as editable text rather than images.
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Perspectives

Cover Letter Cover Letter requirements are not specified.
Abstract A concise and factual abstract is required.
Manuscript Perspectives should generally be 2,000 to 5,000 words. Articles must be divided into clearly defined and numbered sections. Manuscripts must include highlights consisting of 3 to 5 bullet points submitted in a separate editable file, provide keywords immediately after the abstract with a maximum of 6, and include an AI-use disclosure section before the references if generative AI tools were used in manuscript preparation.
References References in the text must be indicated by numbers in square brackets and listed in the order of appearance. References must be numbered in the order they appear in the text, all listed references must be cited in the text and vice versa, and journal names should be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables All figures and all tables must be uploaded, with each illustration submitted as a separate file and captions provided separately for illustrations. Figures must be numbered according to their sequence in the text and include captions, and tables must be submitted as editable text, numbered consecutively, and include titles, descriptions, and footnotes.
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Recent Publications

No expansion of MIS-c associated TCR Vβ 21.3+ T-cells in pediatric Post-COVID condition

Adam J. Tulling, Marloes G. Holierhoek, Savannah N. van der Kroft, Monique M. van Ostaijen-ten Dam, Marlies A. van Houten, Suzanne W.J. Terheggen-Lagro, Gertjan Lugthart, Emilie P. Buddingh

10.1016/j.imlet.2026.107196
View Publication

Characterization of innate immune cells with regulatory functions in subjects with a remote history of Kawasaki disease who lack natural regulatory T cell specificities

Jaeyoon Song, Ruben E. Ruedas Montero, Sophia Y. Hernandez, Adriana H. Tremoulet, Jane C. Burns, Alessandra Franco

10.1016/j.imlet.2026.107197
View Publication

Could bradykinin pathway inhibition change the course of severe hantavirus disease?

Marina Weerheim, Faiz Karim

10.1016/j.imlet.2026.107201
View Publication

Lactate-related diagnostic signature in rheumatoid arthritis: WGCNA and LASSO analysis with experimental validation

Yu Jiang, Cheng Sun, Qiuxia Yu, Hao Liu, YangYang Ding

10.1016/j.imlet.2026.107200
View Publication

Cardiac surgery modulates leucocyte subsets and inflammatory mediators

Alexis J Perros, Kelly Rooks, Fenny Chong, Sanne Engkilde-Pedersen, Arlanna Esguerra-Lallen, Elise Hewlett, Helen M Faddy, Rishendran Naidoo, John-Paul Tung, John F Fraser, Peter Tesar, Marc Ziegenfuss, Susan E Smith, Robert L Flower, Melinda M Dean

10.1016/j.imlet.2026.107187
View Publication

Frequently asked questions

How long does it take to publish?

18 days submission to first decision; 78 days submission to decision after review; 137 days submission to acceptance; 1 day acceptance to online publication

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What are the publication costs?

Open access APC: USD 3290 excluding taxes. Subscription publication: no open access publication fee.

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Research Topics

Immune Cell Function and Interaction T-cell and B-cell Immunology Immunotherapy and Immune Responses Monoclonal and Polyclonal Antibodies Research Immune Response and Inflammation Glycosylation and Glycoproteins Research Cell Adhesion Molecules Research HIV Research and Treatment Immunodeficiency and Autoimmune Disorders Cytokine Signaling Pathways and Interactions CAR-T cell therapy research Diabetes and associated disorders Immune cells in cancer Asthma and respiratory diseases Systemic Lupus Erythematosus Research RNA Interference and Gene Delivery Cancer Immunotherapy and Biomarkers Cytomegalovirus and herpesvirus research Chemokine receptors and signaling Reproductive System and Pregnancy Complement system in diseases Toxin Mechanisms and Immunotoxins vaccines and immunoinformatics approaches Blood groups and transfusion NF-κB Signaling Pathways

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