JO

Journal of Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma is an international, peer-reviewed, open access journal that publishes clinical, translational, and basic research on hepatocellular carcinoma. It covers topics including cell signalling pathways, molecular tumor classification and prognostication, new drugs and therapies, radiology approaches, epidemiology, surveillance, prevention, psychosocial aspects, and quality of life, and welcomes original research manuscripts, reviews, clinical trial reports, expert opinions, and commentaries.

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Subject Oncology
Impact Factor 3.4
Quartile Q2
Open Access Type Open
eISSN 2253-5969
Invitation Only No
Cost Range Publication processing fee applies; invited reviews are exempted from paying any publication processing fee.

Submission Instructions

Journal of Hepatocellular Carcinoma accepts the following article types. Click on an article type to view submission instructions.

Original Research Manuscripts

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 300 words. Abstract must be structured.
Manuscript Manuscript typically includes Abstract, Introduction, Methods, Results, Discussion, and Conclusion sections. Manuscript must include 3–6 keywords and acknowledge the use of AI.
References References must follow American Medical Association (AMA) style. References must be listed numerically in the order cited, use PubMed journal abbreviations, list all authors if there are six or fewer, and list the first three authors followed by "et al." if there are more than six.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included within the manuscript or uploaded as separate files. Tables must be editable rather than images, and figures must not be pasted into the manuscript.
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Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words. Abstract is commonly unstructured and presented in a single paragraph.
Manuscript Reviews are usually structured to provide a summary of existing literature, analysis, and comparison. Manuscript must include 3–6 keywords, and papers must acknowledge the use of AI.
References References must follow American Medical Association (AMA) style. References must be numbered in citation order and should provide a fair and balanced overview without bias toward a particular research group, organization, or journal.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included within the manuscript or uploaded as separate files. Tables must be editable rather than images.
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Clinical Trial Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words.
Manuscript Manuscript must include the clinical trial number and registration date, usually in the abstract and methods sections. Manuscript must include 3–6 keywords and a data sharing statement describing whether deidentified individual participant data will be shared, what data and related documents will be available, how they can be accessed, and when and for how long they will be available.
References References must follow American Medical Association (AMA) style. References must be cited as superscript numerals, listed numerically in order of citation, use PubMed journal abbreviations, list all authors when there are six or fewer, and list the first three authors followed by "et al." when there are more than six.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included within the manuscript or uploaded as separate files. Tables must be supplied in editable format rather than as images.
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Expert Opinions

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words.
Manuscript Each major section of the manuscript should have a heading. Manuscript must include 3–6 keywords, and papers must acknowledge the use of AI.
References References must follow American Medical Association (AMA) style. References must be listed numerically in citation order with superscript numeral citations, list all authors when there are six or fewer, list the first three followed by "et al." when there are more than six, abbreviate journal names according to PubMed, and for Expert Opinions the references must be relevant, fair, balanced, and not unfairly biased toward any research group, organization, or journal.
Figures & Tables Figures must be provided separate from the manuscript, while tables may be included in the manuscript or uploaded as separate files. Tables must be editable and not images, and the manuscript must not contain pasted figures.
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Commentaries

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 300 words.
Manuscript Major sections of the manuscript should each have a heading. Manuscript must include 3–6 keywords and acknowledge the use of AI.
References References must follow AMA style. References must be numbered in citation order, cited in the text as superscript numerals after punctuation, use PubMed journal abbreviations, list all authors when there are six or fewer, list the first three authors followed by "et al." when there are more than six, and for Commentaries be relevant, fair, balanced, and not unfairly biased toward a particular research group, organization, or journal.
Figures & Tables Figures must be uploaded separate from the manuscript, while tables may be included within the manuscript or uploaded as separate files. Tables must be editable and not submitted as images, and figures must not be pasted into the manuscript.
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Recent Publications

Histone Methylation: A Pivotal Epigenetic Driver of the Malignant Transformation of MASLD-HCC

Yan Zhang, Tong Chen, Zhanjie Chang, Xinlei Qi, Ruijuan Yan, Haibo Zhang, Xi Guan, Shuguang Yan, Jingtao Li, Junzhe Jiao

10.2147/jhc.s598429
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When Resectability Emerges After Systemic Therapy in Hepatocellular Carcinoma: A Proposed Response-Guided Consolidation Framework

Yuan Cheng, Kunlin Xie

10.2147/jhc.s613934
View Publication

Impact of Microwave Ablation on Growth Kinetics of Residual versus Synchronous Untreated Hepatocellular Carcinoma: A Retrospective Cohort Study

Wenqi Yi, Chuan Pang, Jingwen Xue, Yi Zhang, Xi Chen, Ting Luo, Dongyun Zhang, Xiaopeng Gao, Jie Yu, Ping Liang

10.2147/jhc.s603442
View Publication

Post-Treatment Prognostic Nutritional Index Outperforms Baseline Index as an Independent Prognostic Biomarker in Advanced Hepatocellular Carcinoma Receiving Immune-Based Systemic Therapy

Xiaochun Chen, Xinkun Guo, Meixia Wang, Guobin Chen, Susu Zheng, Hong Chen, Zhenzhen Zhang, Boheng Zhang

10.2147/jhc.s606554
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Comparable Long-Term Survival After Curative Hepatectomy for Solitary Large (5–10 cm) versus Giant (≥10 cm) Hepatocellular Carcinoma: A Retrospective Study

Kunyuan Jiang, Jingfei Li, Dongli Zhang, Weiping Wang, Jun Chang

10.2147/jhc.s607722
View Publication

Frequently asked questions

How long does it take to publish?

Speed to first decision, speed to first post-review decision, and speed from acceptance to online publication are reported as median numbers of days. Speed metrics cover the previous six months and are updated in February and July. F1000Research publishes submitted articles online in a fully citable format in 14 days.

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Is a cover letter required?

A point-by-point covering letter is required when submitting a revised manuscript after peer review.

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What are the publication costs?

Publication processing fee applies; invited reviews are exempted from paying any publication processing fee.

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Research Topics

Hepatocellular Carcinoma Treatment and Prognosis Cholangiocarcinoma and Gallbladder Cancer Studies Liver Disease Diagnosis and Treatment Ferroptosis and cancer prognosis Cancer Immunotherapy and Biomarkers Radiomics and Machine Learning in Medical Imaging Inflammatory Biomarkers in Disease Prognosis Cancer Mechanisms and Therapy Cancer, Hypoxia, and Metabolism Hepatitis B Virus Studies Cancer, Lipids, and Metabolism Organ Transplantation Techniques and Outcomes Pancreatic and Hepatic Oncology Research Liver Disease and Transplantation Immune cells in cancer Cancer Research and Treatment Hepatitis C virus research Liver physiology and pathology MRI in cancer diagnosis Cancer-related molecular mechanisms research Intraperitoneal and Appendiceal Malignancies Immunotherapy and Immune Responses Cancer Research and Treatments Endoplasmic Reticulum Stress and Disease RNA modifications and cancer

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