JO

Journal of the American College of Cardiology

The Journal of the American College of Cardiology (JACC) is a leading cardiovascular journal program featuring original research, editorials, statistics reports, clinical cases, position statements, and state-of-the-art reviews across the full spectrum of cardiology, including basic, translational, and clinical science. The JACC family of journals encompasses multiple specialized, peer-reviewed titles dedicated to heart health and disease, supporting clinicians, researchers, and other professionals with impactful scientific insights and education.

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Subject Cardiac & Cardiovascular Systems
Impact Factor 22.3
Quartile Q1
Open Access Type Hybrid
ISSN 0735-1097
eISSN 1558-3597
Invitation Only No
Cost Range An open access fee of $7,525 for Original Research publications is payable by authors or on their behalf; rates for other article types are available from the editorial office.

Submission Instructions

Journal of the American College of Cardiology accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter Cover letter must include a statement of ethical approval and, if applicable, any request and rationale for expedited review; it must also disclose any use of artificial intelligence programs in the work.
Abstract Original Research articles must include a structured abstract of no more than 350 words with the headings: Background, Objectives, Methods, Results, Conclusions. A condensed, unstructured abstract of no more than 100 words stressing clinical implications is also required.
Manuscript Original Research manuscripts must not exceed 5,000 words including text from introduction through conclusion, references, and figure legends, and excluding abstract, clinical perspectives, and tables.
References Personal communications, manuscripts in preparation, preprints, and other unpublished data must not be used as numbered references; websites must be cited as references and abstracts older than 2 years should not be cited.
Figures & Tables The main manuscript file must include tables but not figures; figures and supplemental material must be uploaded separately, and any previously published figures or tables require written permission and a cited source in the legend or footnote.
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State-Of-The-Art Review

Cover Letter No specific cover letter requirements are specified.
Abstract An unstructured abstract is required and must not exceed 350 words.
Manuscript Manuscript length must not exceed 10,000 words, excluding references, figure legends, and tables; no specific section structure is specified.
References There is no limit on the number of references, and no specific reference style is specified.
Figures & Tables Up to 6 tables and/or figures (including the Central Illustration) are allowed, and initial submissions may combine text, figures, and tables in a single Word or PDF file with figures and tables placed within the text.
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Meta-analysis

Cover Letter No specific cover letter requirements are specified, including whether a cover letter is required.
Abstract A structured abstract (max 350 words) is required with the headings: Background, Objectives, Methods, Results, Conclusions. An unstructured abstract of up to 100 words, stressing clinical implications must also be provided.
Manuscript Manuscript length must not exceed 5,000 words, excluding references and figure legends; a Key Points section is required, and the article subtitle must include the phrase “A Meta-analysis.”
References There is no limit on the number of references, and no specific reference style is specified.
Figures & Tables Up to 6 tables and/or figures are allowed in total (including the Central Illustration); initial submissions may combine text, figures, and tables in a single Word or PDF file with figures and tables placed within the text.
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Systematic Review

Cover Letter No specific cover letter requirements are specified for this article type.
Abstract An unstructured abstract is required and must not exceed 350 words. An unstructured condensed abstract of up to 100 words, stressing clinical implications must also be provided.
Manuscript Maximum manuscript length is 10,000 words, excluding references, figure legends, and tables; no specific section structure is specified for this article type.
References There is no limit on the number of references, and no specific reference style is specified.
Figures & Tables Up to 6 total tables and/or figures are allowed, including the Central Illustration; initial submissions may combine text, figures, and tables in a single Word or PDF file with figures and tables placed within the text.
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Recent Publications

The Opening Gambit: Thrombectomy to Guide Strategy in STEMI

Ziad A. Ali

10.1016/j.jacc.2026.08.033
View Publication

Stent Retriever Thrombectomy in Patients With Myocardial Infarction The Open-label, Multicenter NATURE Superiority trial

Marco Valgimigli, Enrico Frigoli, Antonio Landi, Marco Covani, Simone Biscaglia, Florim Cuculi, Andrea Erriquez, Matthias Bossard, Antonio Mangieri, Martijn Meuwissen, Juan F. Iglesias, Giuseppe Sangiorgi, Erik Lipšic, Jacopo Andrea Oreglia, Jonas D. Häner, Valeria Paradies, Anna Giulia Pavon, Laura Anna Leo, Felice Gragnano, Federico Fuentes, Vincenzo Viccaro, Antonio Colombo, Sanda Branca, Sergio Leonardi, Hector M. Garcia-Garcia

10.1016/j.jacc.2026.08.034
View Publication

Short-Term Anticoagulant Therapy and Subclinical Leaflet Thickening in Transcatheter Aortic Valves

Troels Højsgaard Jørgensen, Andreas Fuchs Larsen, Jesper Møller Jensen, Rebekka Vibjerg Jensen, Yannick Willemen, Aekapat Phoksiri, Arif Khokhar, Jani Thuraiaiyah, Kamilla Bech Pedersen, Gintautas Bieliauskas, Christian Juhl Terkelsen, Lars Søndergaard, Klaus Fuglsang Kofoed, Bjarne Linde Nørgaard, Ole De Backer, Ole De Backer, Troels Højsgaard Jørgensen, Bjarne Linde Nørgaard, Ole De Backer, Andreas Fuchs, Klaus Kofoed, Ole De Backer

10.1016/j.jacc.2026.08.023
View Publication

Cumulative Benefit With Evolocumab in Patients With No Prior Myocardial Infarction or Stroke in the VESALIUS-CV Study

Jose C. Nicolau, Sabina A. Murphy, Robert P. Giugliano, Lawrence A. Leiter, Gaetano M. De Ferrari, Jeong-Gun Park, Julia Kuder, Lyrica Liu, Huei Wang, Vineet Shastri-Kumar, Oleg Averkov, Vladimir Blaha, Andrej Dzupina, Jorge Ferreira, Johanna Kuusisto, Jose Lopez-Sendon, Alberto J. Lorenzatti, Stephen Nicholls, Daniel Pella, Rimvydas Slapikas, Lale Tokgozoglu, Dragos Vinereanu, Marcoli Cyrille, Marc S. Sabatine, Erin A. Bohula

10.1016/j.jacc.2026.08.015
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Transcatheter Aortic Valve Replacement or Medical Treatment for Paradoxical Low-Flow, Low-Gradient Aortic Valve Stenosis

Julinda Mehilli, Julius Steffen, Tanja Rudolph, Magda Haum, Christina Giannini, Konstantin Stark, Hüseyin Ince, Lenard Conradi, Michael Joner, Andreas Schäfer, Ann-Katrin Karcher, Martin Landt, Matti Adam, Holger Thiele, Tobias Geisler, David Jochheim, Christian Hagl, Uwe Zeymer, Stephan Windecker, Steffen Massberg, Matti Adam, Christof Burgdorf, Lenard Conradi, Christian Frerker, Fernando Gatto, Tobias Geisler, Hüseyin Ince, Michael Joner, Markus Kasel, Jörg Kempfert, Won-Keun Kim, Martin Landt, Norman Mangner, Steffen Massberg, Julinda Mehilli, Helge Möllmann, Margit Niethammer, Anna Sonia Petronio, Thomas Pilgrim, Bernhard Reimers, Jürgen Rothe, Tanja Rudolph, Jörg W. Schröder, Mohammad Sherif, Corrado Tamburino, Giuseppe Tarantini, Holger Thiele, Constantin von zur Mühlen, Alexander Wolf, Uwe Zeymer, Steffen Massberg

10.1016/j.jacc.2026.08.017
View Publication

Frequently asked questions

How long does it take to publish?

Editorial assessment and peer review are designed for rapid decision-making, with only a small percentage of submissions sent for full peer review and accepted articles published online ahead of issue assignment.

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Is a cover letter required?

A cover letter is optional; authors may include one with information they wish the editors to know, and may also request expedited review for appropriate submissions in the cover letter.

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What are the publication costs?

Subscription and pay-per-view options are available for access to many JACC journal articles, alongside selected free access content across the JACC family of journals.

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Research Topics

Cardiac Imaging and Diagnostics Coronary Interventions and Diagnostics Cardiac Valve Diseases and Treatments Cardiovascular Function and Risk Factors Cardiac Arrhythmias and Treatments

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