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npj Digital Medicine

npj Digital Medicine is part of the npj Series, published in partnership with Seoul National University Bundang Hospital, and publishes open access research in digital medicine.

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Subject Health Care Sciences & Services, Medical Informatics
Impact Factor 15.1
Quartile Q1
Open Access Type Open
ISSN 2398-6352
eISSN 2398-6352
Invitation Only No
Cost Range Article processing charges apply; current APCs and waiver information are available via the journal's open access section.

Submission Instructions

npj Digital Medicine accepts the following article types. Click on an article type to view submission instructions.

Article

Cover Letter A cover letter is required with the submission. The cover letter must include the corresponding author's affiliation and contact information.
Abstract An abstract is required. Abstract must not exceed 150 words. Abstract must be unstructured and contain no subheadings.
Manuscript Manuscript must include an Introduction without subheadings, Results with subheadings, a Discussion without subheadings or separate limitations or conclusions sections, and a Methods section with subheadings, with all Methods reported in the main manuscript file. The manuscript must include Data availability, Author contributions, and Competing Interests sections, and must document any use of a large language model in the Methods section or another suitable section if no Methods section is available.
References References are limited to 60. References must use Nature referencing style. References must be numbered sequentially in order of appearance, list all authors unless there are more than five authors in which case only the first author followed by 'et al.' should be given, and include only one publication per reference number.
Figures & Tables At initial submission, figures should be incorporated into the main article file, while tables must be submitted at the end of the text document and figure legends must be placed in the main manuscript after the references. Figure legends must be no more than 350 words per figure, and multi-panel figures must be presented as a single page or file with panels labeled a), b), c).
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Review

Cover Letter A cover letter is required. The cover letter must include the corresponding author’s affiliation and contact information.
Abstract An abstract is required. Abstract must be no more than 70 words. Abstract must be unstructured and contain no subheadings.
Manuscript Main text is typically 3,000–4,000 words in length. Main text may include subheadings. An Author contributions statement naming all authors by initials and a Competing Interests statement declaring each author’s financial and non-financial interests must be included, and any use of a large language model must be documented in the Methods section or another suitable section if no Methods section is available.
References References are limited to 60. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, list all authors unless there are more than five authors in which case the first author is followed by 'et al.', and include only one publication per reference number.
Figures & Tables At initial submission, figures should be incorporated into the main article file and tables should be submitted at the end of the text document, while figure legends must appear in the main manuscript after the references. Figure legends are limited to 350 words per figure, and multi-panel figures must be presented on a single page with panels labeled a), b), c), and so on.
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Brief Communication

Cover Letter A cover letter is required. Cover letter should include the corresponding author's affiliation and contact information.
Abstract An abstract is required. Abstract must be no longer than 70 words. Abstract must be unstructured and contain no subheadings.
Manuscript Main text should be 1,000-1,500 words excluding the abstract, methods, references, and figure legends. Main text must not contain subheadings, while the Methods section should use subheadings and all Methods must appear in the main manuscript file. A Data availability section and an Author contributions statement are mandatory, a Code availability section should be included where applicable, competing interests must be declared, funding should be declared in the Acknowledgments, and use of a large language model must be documented in the Methods section or a suitable alternative section.
References Brief Communications should include around 20 references. References must use Nature style. References must be numbered sequentially in order of appearance, use one publication per reference number, and list all authors unless there are more than five, in which case the first author should be followed by 'et al.'.
Figures & Tables At initial submission, figures should be incorporated into the main article file and tables should be placed at the end of the text document, while for final submission each complete figure must be uploaded as a separate file. Figure legends are limited to 350 words per figure, and multi-panel figures must be presented as a single file on one page with panels labeled a), b), c), and so on.
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Matters Arising

Cover Letter A cover letter must accompany the submission. The cover letter must include the corresponding author's affiliation and contact information and indicate if attempts to contact the original authors were unsuccessful.
Abstract An abstract is required and is provided by the opening summary paragraph. The abstract must not exceed 70 words. The abstract must be unstructured.
Manuscript The main text must not exceed 1,200 words. The contribution must begin with a brief non-specialist summary paragraph that serves as the abstract for submission purposes. An Author contributions statement naming all authors by initials, a Competing Interests statement for each author, and disclosure of large language model use in the manuscript are required.
References The contribution may include up to 15 references. References must use Nature article style. The original research article under discussion must be the first citation, references must be numbered sequentially, and all authors should be listed unless there are more than five, in which case the first author is followed by 'et al.'.
Figures & Tables The article should ideally require only one or two small figures or tables. At submission, figures should be included in the main article file and supplied separately if they cannot be shown clearly there. Figure legends are limited to 350 words per figure, multi-panel figures must be presented on a single page, and panels must be labeled a), b), c).
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Comment

Cover Letter A cover letter is required. Cover letter should include the corresponding author's affiliation and contact information.
Abstract An abstract is required. Abstract must be no longer than 70 words. Abstract must be unstructured and contain no subheadings.
Manuscript Main text is typically 1,000–2,000 words in length. Subheadings are permitted in the main text. Manuscript must include an Author contributions statement naming all authors by their initials, a Competing Interests statement for each author including financial and non-financial interests or a statement of none, and documentation of any large language model use in the manuscript.
References References typically do not exceed 25. References must use standard Nature referencing style. References must be numbered sequentially as they appear, list all authors unless there are more than five in which case the first author is followed by 'et al.', and include only one publication per reference number.
Figures & Tables At initial submission, figures should be incorporated into the main article file and tables must be placed at the end of the text document, while separate figure files are required for final submission. Figure legends are limited to 350 words per figure, and multi-panel figures should appear on a single page with panels labeled a), b), c).
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Editorial

Cover Letter A cover letter must accompany the submission. Cover letter must include the corresponding author's affiliation and contact information.
Abstract An abstract is required. Abstract must be no longer than 70 words. Abstract must be unstructured and contain no subheadings.
Manuscript Main text may use subheadings. Manuscript must include an Author contributions statement identifying each author by initials, a Competing Interests statement declaring financial and non-financial interests for each author or stating none, and documentation of any large language model use in a suitable section of the manuscript.
References References are limited to 60. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, use one publication per reference number, and list all authors unless there are more than five, in which case the first author is followed by 'et al.'.
Figures & Tables At initial submission, figures may be incorporated into the main article file, while tables must be placed at the end of the text document. Figure legends must not exceed 350 words per figure, and multi-panel figures must appear on a single page with panels labeled a), b), c).
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Recent Publications

Delays between CE mark and FDA regulatory approval of AI-enabled software for radiology

Yijun Ren, Daniel Windecker, Isaac Shiri, Christoph Gräni, Alan G. Fraser, Enrico G. Caiani, George CM Siontis

10.1038/s41746-026-03165-5
View Publication

Implementing telemedicine under polycrisis: a mixed-methods case study from Myanmar using the RE-AIM framework

Min Thant Thaw, Kaung Khant Tin, Aung Thura Htoo, Min Zeya, Hein Thu

10.1038/s41746-026-03166-4
View Publication

Clinical decision support in nasopharyngeal carcinoma: comparative evaluation of large reasoning and language models

Lihong Wang, Luxun Wu, Feng Jiang, Yang Yang, Senxiang Yan, Danfang Yan

10.1038/s41746-026-03167-3
View Publication

Integrative metabolic and inflammatory phenotyping identifies cancer cachexia independent of weight history

Zhenyu Huo, Feifei Chong, Siyu Luo, Na Li, Ning Tong, Shiqiao Chen, Zongliang Lu, Yi Tang, Muli Shi, Jing Guo, Ling Zhang, Xin Lin, Mengyuan Zhang, Hongmei Zhang, Xiumei He, Jiuwei Cui, Chunhua Song, Hanping Shi, Hongxia Xu, Wei Li, Chang Wang, Li Deng, Pingping Jia, Kaiying Yu, Dongdong Huang, Min Weng, Zengqing Guo, Jiami Yu, Mei Yang, Fuxiang Zhou, Zhenming Fu, Yuan Lin, Suyi Li, Yi Ba, Ming Liu, Chunling Zhou, Wen Hu, Lan Zhou, Hu Ma, Qinghua Yao, Yi Lu, Minghua Cong, Jiahua Lyu, Xiaoli Tang, Zhikang Chen, Zihua Chen, Gongyan Chen, Qingchuan Zhao, Jipeng Li, Zengning Li, Huiqing Yu, Ying He, Jing Wu, Jin Zheng, Junqiang Chen, Xianghua Wu, Chengle Zhuang, Aiguo Xu, Quanjun Lyu, Min Wang, Xianxu Su, Hui Wang, Ning Lin, Dong Tang, Yaying Yu, Liangyu Yin

10.1038/s41746-026-03123-1
View Publication

Cohort-aware CT-first modeling for clinically oriented pulmonary lesion characterization and prognosis

Jie Peng, Xian Liu, Yaping Quan, Zhongjun Huang, Minfang Wang, Hongyan Luo, Shengxing Liang, Hongbo Zhu, Lushan Xiao

10.1038/s41746-026-03159-3
View Publication

Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 10 days. Median time from submission to acceptance is 144 days.

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Is a cover letter required?

A cover letter is required for all submissions.

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What are the publication costs?

Research Topics

Artificial Intelligence in Healthcare and Education Machine Learning in Healthcare Digital Mental Health Interventions Mobile Health and mHealth Applications AI in cancer detection Radiomics and Machine Learning in Medical Imaging Telemedicine and Telehealth Implementation COVID-19 diagnosis using AI Retinal Imaging and Analysis Electronic Health Records Systems Topic Modeling Mental Health Research Topics Artificial Intelligence in Healthcare Non-Invasive Vital Sign Monitoring Ethics in Clinical Research Sepsis Diagnosis and Treatment Health Systems, Economic Evaluations, Quality of Life Biomedical Text Mining and Ontologies Heart Rate Variability and Autonomic Control ECG Monitoring and Analysis Clinical Reasoning and Diagnostic Skills Explainable Artificial Intelligence (XAI) Parkinson's Disease Mechanisms and Treatments Sleep and related disorders Biomedical and Engineering Education

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