Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Nature Reviews Cardiology publishes Reviews, Research Highlights, News & Views, Comments, Journal Club articles, Tools of the Trade articles, Milestones and related content focused on cardiovascular medicine and research.
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Subject
Cardiac & Cardiovascular Systems
Impact Factor
44.2
Quartile
Q1
Open Access Type
Hybrid
ISSN
1759-5002
eISSN
1759-5010
Invitation Only
Yes
Cost Range
Subscription publication route only; no immediate gold open access option.
Submission Instructions
Nature Reviews Cardiology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:
Review
Cover Letter
Cover Letter requirements are not specified.
Abstract
A 200-word abstract is required for the synopsis, and the article abstract must be unstructured. The abstract should ideally be no more than 200 words. The abstract must be unstructured.
Manuscript
The synopsis must include a brief description of the main article sections, the introduction must be presented without subheadings, and the article must end with a brief concluding summary section without subheadings. The synopsis must include a list of key references and the list of authors with their affiliations, the manuscript must document any LLM use in the Methods section or another suitable section if no Methods section is available, and Review articles in Nature Reviews Cardiology must include 4–6 key point bullet points of 30 words or fewer each.
References
References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers in the order of main text, tables, figures and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
Display items are limited to 7 or fewer tables, figures and boxes in total. Tables must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Display items must be cited in the main text in the format (FIG. 1), tables and boxes must have a short title, and figures must be fully labelled with a short title and a concise legend.
Perspective
Cover Letter
Cover Letter requirements are not specified.
Abstract
A 200-word unstructured abstract is required for the synopsis and the abstract must not contain references or display item citations. The abstract must be 200 words. The abstract must be unstructured.
Manuscript
The main text should follow word count recommendations discussed with the editor. The article must begin with an introduction without subheadings that ends with a guiding paragraph and must end with a brief concluding section without subheadings. Competing interests must be included in the manuscript file, and any use of an LLM must be documented in a suitable part of the manuscript if no Methods section is available.
References
References should be approximately 25 references per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers and listed in the order of main text, tables, figures, and then boxes, with six or more authors shortened to the first author followed by 'et al.'.
Figures & Tables
No more than 5 display items, including tables, figures and boxes, are allowed. Tables and boxes should be provided as part of the article document, while tables containing graphical content should be provided as separate image files. Tables must have a short title, no legend, entries in all cells, and defined abbreviations, and figures must be fully labelled with concise legends that include a short title, descriptions of all components, and definitions of all abbreviations.
Consensus Statement
Cover Letter
Cover Letter requirements are not specified.
Abstract
A 200-word unstructured abstract is required in the synopsis. Abstract must be 200 words. Abstract must be unstructured.
Manuscript
Manuscript must include an introductory section without subheadings, a Methods section describing methodology and stakeholders, and a brief concluding summary section without subheadings. The synopsis must include a brief description of the main article sections, a list of key references, and the list of authors and their affiliations, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript.
References
References should be approximately 25 per 1,000 words, and highlighted key references should comprise 5–10% of the total references. References must use Nature Reviews style. References must be cited as superscript numbers in sequential order through the main text, tables, figures, and boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
Display items are limited to 7 total tables, figures, and boxes. Tables must be provided as part of the article document, whereas tables containing graphical content must be provided as separate image files. Tables must have a short title with entries in all cells and defined abbreviations, figures must be fully labelled with a short title and concise legend, and tables must have no legend.
Evidence-Based Guidelines
Cover Letter
Cover Letter requirements are not specified.
Abstract
A 200-word unstructured abstract is required in the synopsis. Abstract must be 200 words. Abstract must be unstructured.
Manuscript
Manuscript must include an introduction without subheadings, a Methods section describing methodology and stakeholders, and a brief concluding summary section without subheadings. Synopsis must include a brief description of the main article sections, a list of key references, and the list of authors and their affiliations, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript.
References
References should be approximately 25 per 1,000 words. References must use Nature Reviews style. References must be cited as sequential superscript numbers, and if a reference has six or more authors only the first author should be listed followed by 'et al.'.
Figures & Tables
Display items are limited to 7 total tables, figures, and boxes. Tables must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title, no legend, entries in all cells, and defined abbreviations, and each figure must be fully labelled with a short title and a concise legend defining all abbreviations.
News & Views
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract requirements are not specified.
Manuscript
Main text should be around 1,000 words, and the main body plus one display item must fit on 2 print pages. Article must begin with a standfirst of up to 50 words and contain no headings. Only one simple and concise display item may be included, and competing interests must be declared within the article text.
References
Manuscript may include a maximum of 10 references. References must use Nature Reviews style. References must be cited as sequential superscript numbers in the order of main text, tables, figures, and then boxes, and works with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
Only one simple and concise display item may be included. Tables and boxes should be provided as part of the article document, whereas tables containing graphical content must be supplied as separate image files. Figures must be fully labelled with concise legends, and tables must be clear, simple, titled, contain entries in all cells, include definitions for all abbreviations, and have no legend.
Correspondence
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract requirements are not specified.
Manuscript
Main text must not exceed 500 words. No more than two levels of headings are allowed, and the first paragraph must cite the original article. Competing interests must be declared within the text of the article, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References
References must not exceed 10. References must use Nature Reviews reference style. References must be cited as superscript numbers in sequential order through the main text, tables, figures and boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
Only one display item can be included. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title, all cells must contain an entry, abbreviations must be defined, and tables must not include a legend, while each figure must be fully labelled and include a short title and concise legend defining all abbreviations.
Comment
Cover Letter
Cover Letter requirements are not specified.
Abstract
A 200-word abstract is required as part of the submission synopsis. The abstract must be 200 words.
Manuscript
The main text should usually be around 500–600 words or around 1,000–1,200 words. The synopsis must include a brief description of the main article sections, and the Comment itself may use only one level of heading. Comments must include a standfirst of no more than 50 words, and any use of an LLM must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References
Comments may include a maximum of 10 references. References must use Nature Reviews reference style. References must be cited as superscript numbers in sequential order through the main text, tables, figures and then boxes, and references with six or more authors should list only the first author followed by 'et al.'.
Figures & Tables
Only one simple and concise display item may be included, and a single display item or supplementary information may be included at the editor’s discretion. Tables and boxes must be provided as part of the article document, while tables containing graphical content must be provided as separate image files. Tables must have a short title, no legend, at least three columns of data, entries in all cells, and definitions for all abbreviations, while figures must be fully labelled with a short title and a concise legend.
Recent Publications
Fractional flow reserve estimated from the invasive angiogram: limitations and next steps
Nils P. Johnson
10.1038/s41569-026-01302-x
View Publication
CD8+ T cells in atherosclerosis and coronary artery disease
Ishita Tandon, Mohamed Yosri, Hadeer Soliman, Alaa M. Khalifa, Klaus Ley, Hossam A. Abdelsamed
10.1038/s41569-026-01295-7
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Digital screening and decision-support tools in equitable preventive cardiology
Dang Nguyen, Tuan Vinh
10.1038/s41569-026-01299-3
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Base editing and silencing of PCSK9 shows clinical promise in humans
Archna Bajaj, Daniel J. Rader
10.1038/s41569-026-01297-5
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Local calcium dynamics and signalling in cardiomyocytes
Jean-Pierre Benitah, Laetitia Pereira, Romain Perrier, Jean-Jacques Mercadier, Jessica Sabourin, Ana María Gómez
10.1038/s41569-026-01286-8
View Publication
Frequently asked questions
How long does it take to publish?
Accepted manuscripts may be self-archived for public release 6 months after first publication.
Reformat to Nature Reviews Cardiology using Livewrite PremiumWhat are the publication costs?
Subscription journal.
Reformat to Nature Reviews Cardiology using Livewrite PremiumResearch Topics
Atrial Fibrillation Management and Outcomes
Cardiac Imaging and Diagnostics
Cardiovascular Function and Risk Factors
Coronary Interventions and Diagnostics
Cardiac Arrhythmias and Treatments
Lipoproteins and Cardiovascular Health
Cardiac Valve Diseases and Treatments
Antiplatelet Therapy and Cardiovascular Diseases
Cardiac electrophysiology and arrhythmias
Cardiac pacing and defibrillation studies
Acute Myocardial Infarction Research
Heart Failure Treatment and Management
Venous Thromboembolism Diagnosis and Management
Blood Pressure and Hypertension Studies
Atherosclerosis and Cardiovascular Diseases
Cardiomyopathy and Myosin Studies
Diabetes, Cardiovascular Risks, and Lipoproteins
Cerebrovascular and Carotid Artery Diseases
Mechanical Circulatory Support Devices
Cardiac Fibrosis and Remodeling
Cardiac, Anesthesia and Surgical Outcomes
Heart Rate Variability and Autonomic Control
Cardiac Arrest and Resuscitation
Infective Endocarditis Diagnosis and Management
Cardiac Structural Anomalies and Repair