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Pharmacology & Therapeutics

Pharmacology & Therapeutics publishes lucid, critical, and authoritative reviews on important topics in pharmacology, including drug actions and the exploitation of drug targets. Disease pathophysiology is covered when it forms part of a narrative around drug actions or new drug targets. Founded in 1976, the journal is among the top 10 most cited journals in pharmacology.

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Impact Factor 12.5
Quartile Q1
Open Access Type Hybrid
ISSN 0163-7258
eISSN 1879-016X
Invitation Only Yes
Cost Range Open access APC: USD 5380 excl. taxes for all articles; subscription publication has no open access publication fee.

Submission Instructions

Pharmacology & Therapeutics is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words.
Manuscript Articles should be divided into clearly defined and numbered sections. The manuscript must include 1 to 7 English keywords and, if generative AI was used in manuscript preparation, a declaration in a separate section before the references list.
References Citations in the text must follow American Psychological Association style. The reference list must be arranged alphabetically and then chronologically, with same-author same-year entries distinguished by letters such as a, b, and c.
Figures & Tables Tables must be placed next to the relevant text or on separate pages at the end of the article, and figures must be supplied as separate files along with the manuscript. Tables must be submitted as editable text rather than images.
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Recent Publications

Novel therapeutic targets and drug discovery strategies in chronic obstructive pulmonary disease

Jiejie Hao, Zhengxin Liu, Yupeng Zhi, Ling Lu, Ximing Xu, Fang Lu, Xinglong Dai

10.1016/j.pharmthera.2026.109040
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Advances in iron-based chemodynamic anti-cancer therapy

Yuying Dai, Lu An

10.1016/j.pharmthera.2026.109028
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The aftermath of alcohol misuse: Linking cellular damage, suboptimal micronutrient nutrition, and organ dysfunction

Janos Paloczi, Lauri O. Byerley, Stefany D. Primeaux

10.1016/j.pharmthera.2026.109038
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The role of MyD88 in the nervous system: Neuronal functions, implications in neurological diseases, and therapeutic potential

Hai-Li Pan, Jia-Yi Ge, Zi-Ang Zhang, Jia-Huan Xu, Jia-Ni Wu, Yi Ju, Xi-Yu Zhang, Zuo-Jie Jiang, Yong Chen, Yun-Zhao Xu, Xing-Jun Liu

10.1016/j.pharmthera.2026.109016
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Autophagy–exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities

Samin Sedighi, Teng Guan, Federica Michetti, Marco Cordani, Amir Barzegar Behrooz, Farzaneh Sabouni, Mehdi Eshraghi, Ayesha Saleem, Saeid Ghavami, Mohamad-Reza Aghanoori

10.1016/j.pharmthera.2026.109025
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Frequently asked questions

How long does it take to publish?

9 days from submission to first decision; 56 days from submission to decision after review; 146 days from submission to acceptance; 4 days from acceptance to online publication.

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What are the publication costs?

Open access APC: USD 5380 excl. taxes for all articles. Subscription publication has no open access publication fee.

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Research Topics

Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology Research Diverse Scientific and Economic Studies Human auditory perception and evaluation Educational Robotics and Engineering Pharmacogenetics and Drug Metabolism Neuropeptides and Animal Physiology Ion channel regulation and function Neurotransmitter Receptor Influence on Behavior Drug Transport and Resistance Mechanisms Asthma and respiratory diseases Cardiac electrophysiology and arrhythmias Eicosanoids and Hypertension Pharmacology Nitric Oxide and Endothelin Effects Nicotinic Acetylcholine Receptors Study Monoclonal and Polyclonal Antibodies Research Computational Drug Discovery Methods Epigenetics and DNA Methylation Adenosine and Purinergic Signaling Protein Kinase Regulation and GTPase Signaling Cancer, Hypoxia, and Metabolism Biochemical and Molecular Research Cannabis and Cannabinoid Research Tryptophan and brain disorders Pain Mechanisms and Treatments