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Value In Health

Value in Health is ISPOR’s health economics and outcomes research journal. It publishes papers that advance the science of HEOR globally, including new methods, best practice guidelines, innovative research, and ISPOR Good Practices Reports intended to influence healthcare decision making worldwide.

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Impact Factor 6
Quartile Q1
Open Access Type Hybrid
ISSN 1098-3015
eISSN 1524-4733
Invitation Only No
Cost Range Gold open access is available for a fee, with possible institutional coverage or discounts for ISPOR members; subscription publication is also available, and all content becomes open archive 1 year after publication.

Submission Instructions

Value In Health accepts the following article types. Click on an article type to view submission instructions.

Systematic Literature Reviews

Cover Letter A cover letter is required. Cover letter must briefly describe the article, explain its interest to readers and contribution to the literature, note any themed section submission, provide the full title and subtitle in no more than 25 words, state whether the data, models, or methodology are proprietary, disclose financial and material support and grant numbers, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include Objectives, Methods, Results, and Conclusions headings.
Manuscript Manuscript must not exceed 4000 words. Manuscript should review empirical studies consistent with Cochrane Collaboration methods and follow PRISMA 2020 reporting guidelines. Manuscript must include 3 to 6 keywords after the abstract, 3 highlight statements with a combined total of no more than 120 words, and a disclosure stating whether artificial intelligence or AI-assisted technologies were used and how they were used.
References References must use AMA style. References must be cited with superscript Arabic numerals and numbered consecutively in order of citation, and for references with 6 or more authors only the first 3 should be listed followed by et al.
Figures & Tables Figures must be submitted as separate image files and not embedded in the text, and tables must not be embedded in the main document and must be submitted in an editable format such as Word or Excel. Figures and tables must be numbered, figures must include titles and legends with each legend on a separate page, and each table must have a title on a separate page.
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Original Research

Cover Letter A cover letter is required. The cover letter must briefly describe the article, explain its interest to readers and contribution to the literature, note any themed section submission, provide the full title and subtitle in no more than 25 words, state whether data/models/methodology are proprietary, disclose all financial and material support including grant numbers, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include Objectives, Methods, Results, and Conclusions.
Manuscript Original Research manuscripts must not exceed 4000 words, excluding the abstract, references, figure legends, tables, and appendices or supplemental materials. The manuscript body should be divided into Introduction, Methods, Results, Discussion, and Conclusions sections as appropriate. The manuscript must include 3 to 6 keywords after the abstract, 3 highlight statements with a combined total of no more than 120 words, a patient engagement statement if applicable, an AI-use disclosure if applicable, and sensitivity analysis for modeling papers.
References References must use AMA style. References must be cited in the text with superscript Arabic numerals and listed consecutively in citation order, with only the first 3 authors named followed by et al when a reference has 6 or more authors.
Figures & Tables Figures and tables must not be embedded in the main document and must be submitted separately, with figures as separate image files and tables in an editable format. Figures and tables must be numbered and cited consecutively in Arabic numerals, figures must include a brief title and a separate double-spaced legend page, and each table must have a title on a separate page.
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Economic Evaluations

Cover Letter A cover letter addressed to the editors-in-chief is required. Cover letter must briefly describe the article, explain its interest to readers and contribution to the literature, indicate any themed section, provide the full title and subtitle within 25 words, state whether data, models, or methodology are proprietary, disclose all financial and material support and grant numbers, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include Objectives, Methods, Results, and Conclusions.
Manuscript No article-type-specific manuscript word or page limit is stated. Manuscript body should be divided into Introduction, Methods, Results, Discussion, and Conclusions sections as appropriate. Manuscript must include 3 to 6 keywords after the abstract, 3 highlight statements with a combined maximum of 120 words, a patient involvement statement if applicable, and a disclosure of any artificial intelligence or AI-assisted technologies used and how they were used.
References References must use AMA style. References must be cited in the text with superscript Arabic numerals and listed consecutively in citation order, and references with 6 or more authors must list the first 3 followed by et al.
Figures & Tables Figures and tables must not be embedded in the manuscript and must be submitted separately, with figures as separate image files and tables in an editable format such as Word or Excel. Figures and tables must be numbered and titled, figure legends must be provided on a separate page, and all abbreviations or symbols used must be explained in the legend or below the table.
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Patient-Reported Outcomes

Cover Letter A cover letter is required. The cover letter must briefly describe the article, explain its interest and contribution to the literature, state any themed section submission, provide the full title and subtitle in no more than 25 words, disclose whether data/models/methodology are proprietary, disclose all financial and material support including grant numbers, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include the headings Objectives, Methods, Results, and Conclusions.
Manuscript The manuscript body should be divided into Introduction, Methods, Results, Discussion, and Conclusions sections as appropriate. The manuscript must include 3 to 6 keywords after the abstract, 3 highlight statements with a combined maximum of 120 words, a statement explaining how patients were involved if the research engaged patients, and a disclosure of whether AI or AI-assisted technologies were used and how they were used.
References References must use AMA style. References must be cited in the text with superscript Arabic numerals, listed consecutively in citation order, and for works with 6 or more authors only the first 3 authors should be listed followed by et al.
Figures & Tables Figures and tables must not be embedded in the manuscript and must be submitted separately, with figures as separate image files and tables in an editable format such as Word or Excel. Figures and tables must be numbered and cited consecutively in the text, figures must include titles and legends on a separate page, and each table must have a title on a separate page.
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Preference-Based Assessments

Cover Letter A cover letter addressed to the editors-in-chief is required. Cover letter must briefly describe the article, explain its interest to readers and contribution to the literature, state whether it is for a themed section, provide the full title and subtitle in no more than 25 words, disclose whether the data, models, or methodology are proprietary, list all financial and material support and grant numbers, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include Objectives, Methods, Results, and Conclusions.
Manuscript Manuscript body should be divided into Introduction, Methods, Results, Discussion, and Conclusions sections as appropriate. Manuscript must include 3 to 6 keywords after the abstract, 3 highlight statements with a combined maximum of 120 words, a patient-engagement statement if applicable, an AI-use disclosure if applicable, and for Preference-Based Assessments a copy of the survey instrument used to generate the preference data translated into English if originally in another language and uploaded as a Supplemental File for Review if not intended for publication.
References References must use AMA style. References must be cited with superscript Arabic numerals and listed consecutively in citation order, and references with 6 or more authors must list the first 3 followed by et al.
Figures & Tables Figures must be submitted as separate image files and not embedded in the text, and tables must not be embedded in the main document and must be submitted in an editable format such as Word or Excel. Figures and tables must be numbered and cited consecutively, each figure must have a brief title and a separate legend page, and each table must have a title on a separate page.
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Brief Reports

Cover Letter A cover letter is required. Cover letter must briefly describe the article, explain its interest to readers and contribution to the literature, note any themed section submission, provide the full title and subtitle in no more than 25 words, state whether the data, models, or methodology are proprietary, disclose financial and material support including funders and grant numbers, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must include Objectives, Methods, Results, and Conclusions.
Manuscript Brief Reports must not exceed 2500 words. Manuscript body should be divided into Introduction, Methods, Results, Discussion, and Conclusions sections as appropriate. Manuscript must include 3 to 6 keywords after the abstract, 3 highlight statements with a combined total of no more than 120 words, and a disclosure stating whether artificial intelligence or AI-assisted technologies were used and how they were used.
References References must use AMA style. References must be cited in the text with superscript Arabic numerals, listed consecutively in the order cited, and for references with 6 or more authors only the first 3 authors should be listed followed by et al.
Figures & Tables Figures and tables must not be embedded in the main document and must be submitted separately, with figures as separate image files and tables in an editable format such as Word or Excel. Figures and tables must be numbered, figures must have brief titles and separate legends, and tables must each have a title on a separate page.
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Letters To The Editor

Cover Letter A cover letter addressed to the editors-in-chief is required. The cover letter must briefly describe the article, explain its interest to readers and contribution to the literature, state whether it is for a themed section, provide the full title and subtitle in no more than 25 words, indicate whether the data, models, or methodology are proprietary, disclose all financial and material support including grant numbers where applicable, state that publication was not contingent on sponsor approval or censorship, and give the corresponding author's full name, degree, department, institution, and email address.
Abstract An abstract is not required for Letters To The Editor.
Manuscript Letters To The Editor must not exceed 1500 words. The submission must include 3 to 6 keywords, 3 highlight statements with a combined maximum of 120 words, and a disclosure of whether artificial intelligence or AI-assisted technologies were used and how they were used.
References References must use AMA style. References must be cited in the text with superscript Arabic numerals, listed consecutively in citation order, and for references with 6 or more authors only the first 3 should be listed followed by et al.
Figures & Tables Figures and tables must not be embedded in the manuscript and must be submitted separately, with figures as separate image files and tables in an editable format such as Word or Excel. Figures and tables must be numbered and cited consecutively in the text, figures must include titles and legends on a separate page, and tables must have a title on a separate page.
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Recent Publications

Modelling Approaches to the Economic Evaluation of Micro-Elimination strategies for HCV in High-Risk Populations: A Systematic Review

Ying Chen, Yun Bao, Yueting Chen, Mengxia Yan, Kaijie Yao, Wen Li, Bin Wu

10.1016/j.jval.2026.03.2248
View Publication

Evaluating Policy Options for New Treatments Under Uncertain External Evidence

Yizhi Liang, Boshen Jiao

10.1016/j.jval.2026.03.2240
View Publication

Impact of Smoothing and Modeling Approach on Quality-Adjusted Life Expectancy Estimates

Hosein Ameri, Thomas G. Poder

10.1016/j.jval.2026.03.2241
View Publication

A systematic review of quantitative health preference methods to support value clarification and shared-decision making: A report of an ISPOR special interest group.

Janine van Til, Holly L. Peay, Ahmed Osman, Angie Botto-van Bemden, Caitlin Thomas, Carina Oedingen, Caroline Vass, Elise Schoefs, Laurie Batchelder, Semra Ozdemir, Christine Poulos

10.1016/j.jval.2026.03.2243
View Publication

Validation and Clinical Meaningfulness of the 18-item National Comprehensive Cancer Network-Functional Assessment of Cancer Therapy (NCCN-FACT) Lymphoma Symptom Index (NFLymSI-18) in Patients with Lymphoma

Kimberly A. Webster, Anne R. Zola, Maria Corona, Elijah A. Patten, Reem Karmali, Leo Gordon, Shuo Ma, Jane N. Winter, Alexander Upton, John Devin Peipert, David Cella

10.1016/j.jval.2026.03.2244
View Publication

Frequently asked questions

How long does it take to publish?

Median 21 days from acceptance to first online publication.

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Is a cover letter required?

A cover letter is required and should be addressed to the editors-in-chief. It should include a brief description of the article, why it is of interest to the journal's readership, any themed section submission, contribution to the literature, title, statement on proprietary data, funding/support, role of sponsor, and corresponding author contact information.

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What are the publication costs?

Gold open access is available for a fee. Subscription publication is available without an open access fee, and all published content becomes freely accessible 1 year after publication.

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Research Topics

Health Systems, Economic Evaluations, Quality of Life Pharmaceutical Economics and Policy Economic and Financial Impacts of Cancer Healthcare Policy and Management Pharmaceutical studies and practices Medication Adherence and Compliance Pharmaceutical Practices and Patient Outcomes Biosimilars and Bioanalytical Methods Global Health Care Issues Diabetes Treatment and Management Chronic Disease Management Strategies Diabetes Management and Research Healthcare Systems and Reforms Healthcare cost, quality, practices Statistical Methods in Clinical Trials Rheumatoid Arthritis Research and Therapies Hepatitis C virus research Biomedical Ethics and Regulation Lung Cancer Treatments and Mutations Chronic Lymphocytic Leukemia Research Vaccine Coverage and Hesitancy Pharmaceutical industry and healthcare Innovation Policy and R&D Healthcare Systems and Public Health Cardiac, Anesthesia and Surgical Outcomes