AP

Acta Pharmacologica Sinica

Acta Pharmacologica Sinica is a pharmacology journal published on the Nature platform that publishes research articles and review articles and includes both subscription and open access content.

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Subject Pharmacology & Pharmacy
Impact Factor 8.4
Quartile Q1
Open Access Type Hybrid
ISSN 1671-4083
eISSN 1745-7254
Invitation Only No
Cost Range £2990.00/$4590.00/€3890.00 APC for open access; no APC under the traditional publishing model.

Submission Instructions

Acta Pharmacologica Sinica accepts the following article types. Click on an article type to view submission instructions.

Review Article

Cover Letter Cover letter is required. Cover letter must state that the material is not under consideration elsewhere and must provide the corresponding author's name, full postal address, and e-mail address.
Abstract Abstract is required. Abstract must be non-structured and must not exceed 350 words. Abstract must be non-structured.
Manuscript Manuscript must not exceed 8000 words excluding references. Manuscript should generally be divided into Title page, Abstract, Keywords, Introduction, Material and methods, Results, Discussion, Acknowledgements, Author contribution, References, Tables, Figures, and Supplementary information. Manuscript must include 3–6 keywords below the abstract and an author contribution section.
References References must be numbered consecutively in the text as superscripts and listed individually at the end, with journal titles abbreviated in MEDLINE style and up to six authors listed before using et al. for seven or more authors.
Figures & Tables Tables should be supplied as separate electronic files in Word or Excel format. Tables and figures must be labeled sequentially, tables must have at least two columns with headings, and each figure must be self-explanatory.
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Article

Cover Letter A cover letter is required. The cover letter must state that the material is not under consideration elsewhere and must provide the corresponding author’s name, full postal address, and e-mail address.
Abstract An abstract is required. Abstract must be non-structured and less than 350 words. Abstract must be unstructured.
Manuscript Manuscript should generally be divided into Title page, Abstract, Keywords, Introduction, Material and methods, Results, Discussion, Acknowledgements, Author contribution, References, Tables, Figures, and Supplementary information. Manuscript must include 3–6 keywords below the abstract, an author contribution statement, any trial registry number where applicable, and the chemical structure of new compounds or a citation to the published structure.
References References must be numbered consecutively in the text as superscripts and listed individually at the end, with journal titles abbreviated in MEDLINE style and up to six authors listed in full or the first six followed by et al. for seven or more authors.
Figures & Tables Tables should be supplied as separate electronic files in Word or Excel format. Tables and figures must be labeled sequentially, each figure must be self-explanatory, and figure legends must begin on a separate page.
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Brief Communication

Cover Letter A cover letter is required. Cover letter must state that the material is not under consideration elsewhere and provide the corresponding author’s name, full postal address, and e-mail address.
Abstract An abstract is required. Abstract must not exceed 350 words. Abstract must be unstructured.
Manuscript Brief Communications are not required to divide the text into sections. The manuscript must include 3–6 keywords below the abstract and an author contribution statement.
References References must be numbered consecutively in the text as superscripts and listed numerically at the end, with journal titles abbreviated in MEDLINE style and up to six authors listed before using et al.
Figures & Tables Tables should be supplied as separate electronic files in Word or Excel format. Tables and figures must be numbered sequentially, and each figure must be self-explanatory.
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Correspondence

Cover Letter A cover letter is required. Cover letter must state that the material is not under consideration elsewhere and must provide the corresponding author's name, full postal address, and e-mail address.
Abstract Abstract is not required.
Manuscript Correspondence must contain no more than 1000 words of text.
References Correspondence may include a maximum of 10 references. References must be numbered consecutively in the text as superscripts and listed individually at the end, with up to six authors named in full or the first six followed by et al. for seven or more authors.
Figures & Tables Correspondence may contain one display item in total, either one figure or one table. Tables should be supplied as separate electronic files in Word or Excel format.
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Recent Publications

Metabolic checkpoint blockade of IL4I1 by ZY-MY-111 reactivates CD8+ T cell immunity and suppresses tumor growth

Ju-fei Li, Hao Wang, Ling Kang, Cheng-cheng Xu, Yuan-chun Liu, Zi-xuan Li, Shao-hao Lin, Ming-zhi Wang, Xiao-min Xu, Pei-pei Wang, Wan-chao Yin, Yu-bo Zhou, Yu Zhou, Jia Li

10.1038/s41401-026-01843-4
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Repurposing atorvastatin for uterine leiomyosarcoma: mevalonate pathway inhibition yields preclinical antitumor efficacy

Fang-liang Zhou, Yi-bin Wu, Wen Wang, Bin-jie Yan, Ying-chun He, Xi-Long Zheng

10.1038/s41401-026-01823-8
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Time-resolved proteomic and phosphoproteomic analysis reveals convergent and divergent biological perturbations induced by FDA-approved CDK4/6 inhibitors in hormone receptor-positive breast cancers

Shi-yu Duan, Lin-hui Zhai, Wei Zhang, Luo-yi Chen, Rui-xi Zhao, Xun Zou, Jia-hui Ni, Xing-long Jia, Tian-yu Liu, Hang Fu, Min Huang, Min-jia Tan, Cheng-yu Chu, Yi-ting Jin

10.1038/s41401-026-01858-x
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ApoE impairs microglial efferocytosis by targeting Gas6/MerTK in a mouse model of acute seizure

Bo Gao, Si-min Cheng, Yu-yan Zhang, Hui-xia Yang, Ming-ming Hu, Yu Wang, Jian-ming Han, Li Yu, Shun-zhi Cao, Kun Dong, Hua Kong, Wen-ning Wu

10.1038/s41401-026-01842-5
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Echoes in the powerhouse: mito-lncRNAs contribution to cardiac function and disease

Abdallah Iddy Chaurembo, Na Xing, Zi-feng Huang, Baraka Simon Mayamba, Francis Chanda, Yun-tao Liang, Yong-fang Lin, Wen-hui Deng, Jian-yuan Huang, Zeng-yu He, Zheng Tan, Chi Shu, Han-bin Lin

10.1038/s41401-026-01830-9
View Publication

Frequently asked questions

How long does it take to publish?

25 days from submission to the first decision; 30 days from acceptance to online publication.

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What are the publication costs?

Open access APC: £2990.00/$4590.00/€3890.00, subject to VAT or local taxes where applicable. Traditional publishing model: no APC.

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Research Topics

Autophagy in Disease and Therapy Ion channel regulation and function Neuroscience and Neuropharmacology Research Receptor Mechanisms and Signaling Neuroinflammation and Neurodegeneration Mechanisms Traditional Chinese Medicine Analysis Cell death mechanisms and regulation Cardiac electrophysiology and arrhythmias Drug Transport and Resistance Mechanisms Cancer, Hypoxia, and Metabolism Ubiquitin and proteasome pathways Neuropeptides and Animal Physiology Neurotransmitter Receptor Influence on Behavior Liver Disease Diagnosis and Treatment Immune Response and Inflammation Cardiac Ischemia and Reperfusion Nicotinic Acetylcholine Receptors Study MicroRNA in disease regulation Endoplasmic Reticulum Stress and Disease Pharmacogenetics and Drug Metabolism Inflammasome and immune disorders Nitric Oxide and Endothelin Effects Computational Drug Discovery Methods Protein Kinase Regulation and GTPase Signaling Ginseng Biological Effects and Applications

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