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Annals of Hepatology

Annals of Hepatology is an international open access journal in hepatology published bi-monthly with funds from Fundación Clínica Médica Sur. It is the official journal of the Mexican Association of Hepatology, the Latin American Association for the Study of the Liver, the Canadian Association for the Study of the Liver, and the Czech Society of Hepatology, and publishes editorials, opinions, concise reviews, original articles, brief reports, letters to the editor, news from affiliated associations, clinical practice guidelines, and summaries of congresses focused on liver disease and translational research.

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Subject Gastroenterology & Hepatology
Impact Factor 4.4
Quartile Q1
Open Access Type Open
ISSN 1665-2681
eISSN 1665-2681
Invitation Only No
Cost Range Article Publishing Charge: USD 500 for Case Reports; USD 1000 for Original Articles, Reviews, and Practice Guidelines under the stated funding plan; 33.33% discount offered for eligible submissions.

Submission Instructions

Annals of Hepatology accepts the following article types. Click on an article type to view submission instructions.

Concise Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 250 words.
Manuscript Manuscript must be no longer than 5,000 words. Manuscript must be divided into clearly defined sections using headings. Manuscript must include 1 to 6 keywords in English, and any use of generative AI in manuscript preparation must be declared in a new section before the references list.
References References must not exceed 150. Citations must use superscript numbers in the text, references must be numbered in order of appearance, references with more than 6 authors must list the first 6 followed by et al., and journal names must be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Tables must be included in the anonymized manuscript, while figures and other artwork must be supplied as separate files along with the manuscript. Tables must be submitted as editable text with captions and cited in the manuscript text, and all artwork must have captions and be cited in the manuscript text.
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Original Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A concise factual abstract is required. Abstract must not exceed 250 words.
Manuscript Original Articles must not exceed 4,000 words excluding references. Manuscripts must be divided into clearly defined sections using headings. Manuscripts must include 1 to 6 keywords in English, and any use of generative AI in manuscript preparation must be declared in a new section placed before the references list.
References Original Articles must include no more than 50 references. References must be cited in the text using superscript numbers and listed in numerical order of appearance, with more than 6 authors shortened to the first 6 followed by et al.
Figures & Tables Tables must be included in the anonymized manuscript, while figures and other artwork must be supplied as separate files. Tables must be editable text with captions and consecutive numbering, and all figures and artwork must be cited in the text, numbered in order, and accompanied by captions.
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Brief Reports

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract must be concise and factual.
Manuscript Brief Reports must not exceed 1,500 words. Brief Reports must use the same sections, format, and guidelines as Original Articles, and the manuscript must be divided into clearly defined sections using headings. Manuscript must include 1 to 6 keywords in English and, if generative AI tools were used in manuscript preparation, a declaration statement must be added in a new section before the references list.
References References must be cited in the text using superscript numbers and listed in numerical order of appearance, with more than 6 authors shortened to the first 6 followed by et al.
Figures & Tables Tables must be included in the anonymized manuscript, while figures and other artwork must be supplied as separate files along with the manuscript. Tables must be editable text with captions and consecutive numbering, and all figures and tables must be cited in the manuscript text.
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Clinical Letters

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not be included.
Manuscript Manuscript must not exceed 1,500 words excluding title page information, references, and any figure or table legends. Manuscript must be divided into clearly defined sections using headings. Manuscript must include 1 to 6 keywords in English, and any use of generative AI in manuscript preparation must be declared in a new section before the references list at initial submission.
References Reference list must contain no more than 4 references. References must be cited with superscript numbers in the text and listed in numerical order, with more than 6 authors shortened to the first 6 followed by et al.
Figures & Tables No more than 2 figures or tables combined may be included. Tables must appear in the anonymized manuscript, while figures, images, diagrams, and other artwork must be uploaded as separate files. Tables must be submitted as editable text with captions and all figures and tables must be cited and numbered consecutively.
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Correspondence

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Correspondence must contain no more than 500 words. Manuscripts must be divided into clearly defined sections using headings. Manuscripts must include 1 to 6 keywords in English and, if generative AI tools were used in preparation, an AI declaration section must be added before the references list.
References Correspondence must include a minimum of 15 references. References must be cited as superscript numbers in the text and listed in numerical order of appearance, with more than 6 authors shortened to the first 6 followed by et al.
Figures & Tables Tables must be included in the anonymized manuscript, while figures and other artwork must be supplied as separate files. Tables must be editable text with captions and consecutive numbering, and all figures and artwork must have captions and be numbered in order of appearance.
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Clinical Practice Guidelines

Cover Letter Cover Letter requirements are not specified.
Abstract A non-structured abstract is required for this article type. Abstract must not exceed 200 words. Abstract must be non-structured.
Manuscript Main text must not exceed 6,000 words, excluding the abstract, references, tables, and figures. Manuscript must report the methodology used to generate the recommendations, as well as the levels of evidence and strength of recommendation if applicable. Manuscript must include 1 to 6 keywords in English and, if generative AI tools were used in manuscript preparation, a declaration statement in a new section before the references list.
References References must be cited with superscript numbers and listed in numerical order of first appearance, with more than 6 authors shortened to the first 6 followed by et al.
Figures & Tables Tables must be included in the anonymized manuscript, while figures and other artwork must be uploaded as separate files. Tables must be editable text with captions and consecutive numbering, and all figures and artwork must be cited in the text and supplied with captions.
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Position Papers

Cover Letter Cover Letter requirements are not specified.
Abstract A non-structured abstract is required for Position Papers. Abstract must not exceed 200 words. Abstract must be non-structured.
Manuscript Main text must not exceed 6,000 words, excluding abstract, references, tables, and figures. Manuscript must report the methodology used to generate the recommendations, as well as the levels of evidence and strength of the recommendation if applicable. The anonymized manuscript must include 1 to 6 keywords in English and, if generative AI tools were used in manuscript preparation, a declaration statement must be added in a new section before the references list.
References References must be cited with superscript numbers and listed in numerical order of appearance, with more than 6 authors shortened to the first 6 followed by et al.
Figures & Tables Tables must be included in the anonymized manuscript, while figures and other artwork must be uploaded as separate files. Tables must be submitted as editable text with captions and figures must each have a caption and be cited in the text.
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Recent Publications

Impact of metabolic dysfunction-associated steatotic liver disease on the development of hepatocellular carcinoma after HCV cure

Eiichi Ogawa, Akira Kawano, Motoyuki Kohjima, Toshimasa Koyanagi, Kazufumi Dohmen, Aritsune Ooho, Takeaki Satoh, Kazuhiro Takahashi, Norihiro Furusyo, Eiji Kajiwara, Koichi Azuma, Yasunori Ichiki, Rie Sugimoto, Hiromasa Amagase, Masatake Tanaka, Hideyuki Nomura, Jun Hayashi

10.1016/j.aohep.2026.102455
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Mapping the preclinical therapeutic landscape of cirrhotic portal hypertension: a systematic evidence map

Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Verónica Arreaza-Gil, Jordi Gracia-Sancho

10.1016/j.aohep.2026.102463
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Beyond portal pressure reduction: Interpreting the survival benefit of statin add-on therapy in portal hypertension

Yun Liao, Lihua Feng

10.1016/j.aohep.2026.102462
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Endoscopy timing in managing acute esophagogastric variceal bleeding: a multicenter retrospective study

Xinhui Li, Chunying Wang, Qun Li, Yuchen Lu, Wenbo Li, Minghui Wang, Yueyue Li, Yong Chen, Shuang Zhao, Qianqian Dong, Feifei Fan, Jing Wang, Xiaofeng Liu

10.1016/j.aohep.2026.102459
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Antimicrobial resistance in invasive infections among patients with cirrhosis in Latin America: A multicenter registry

Emilse Daniela Diaz Lobo, Gonzalo Gómez Perdiguero, Astrid Smud, María Dolores Murga, Ana Palazzo, Esteban González Ballerga, Ilse Sorena Pardo Ivirico, María Daniela Pérez, Lorena Notari, Josefina Pages, Manuel Mendizabal, Camila María Briz, Agustín Di Santo, Julia Brutti, Brenda Osso Sánchez, Margarita Anders, Pablo Calzetta, Alina Zerega, Angelo Z. Mattos, Laura R. Maboni, Maximiliano Castro, Fernando Cairo, Lucia Navarro, Martin Elizondo, Gisela Gualano, Maria Laura Garrido, Diego Hernan Giunta, Diego Arufe, Marcelo Valverde, Agostina Romero, Natalie Vilcinskas, Jorge Garavito Rentería, Javier Diaz Ferrer, Rommel Zambrano Huailla, Laura Tenorio Castillo, Karla Aquino Vargas, Esther Veramendi Shult, Melisa Dirchowlf, Jesica Tomatis, Adrián Gadano, Sebastián Marciano

10.1016/j.aohep.2026.102461
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Frequently asked questions

How long does it take to publish?

8 days from submission to first decision.

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What are the publication costs?

Article Publishing Charge: USD 500 for Case Reports; USD 1000 for Original Articles, Reviews, and Practice Guidelines under the stated funding plan; 33.33% discount offered for eligible submissions.

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Research Topics

Liver Disease Diagnosis and Treatment Liver Disease and Transplantation Hepatitis C virus research Hepatitis B Virus Studies Organ Transplantation Techniques and Outcomes Liver Diseases and Immunity Hepatocellular Carcinoma Treatment and Prognosis Drug-Induced Hepatotoxicity and Protection Alcohol Consumption and Health Effects Liver physiology and pathology Hepatitis Viruses Studies and Epidemiology Pediatric Hepatobiliary Diseases and Treatments Gallbladder and Bile Duct Disorders Diet, Metabolism, and Disease Cholangiocarcinoma and Gallbladder Cancer Studies Pancreatitis Pathology and Treatment Drug Transport and Resistance Mechanisms Renal Transplantation Outcomes and Treatments Diabetes, Cardiovascular Risks, and Lipoproteins Nutrition and Health in Aging Diet and metabolism studies Diverse Scientific and Economic Studies COVID-19 Clinical Research Studies Folate and B Vitamins Research Human auditory perception and evaluation

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